Levodopa - epgonline.org
Levodopa - epgonline.org
Levodopa - epgonline.org
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ENT416_NURSES LEAVEPIECE.qxd 2/10/06 14:08 Page 14<br />
Upgrading to Stalevo ®<br />
• Patients can be switched directly to an equivalent dose of levodopa if<br />
they are:<br />
– Experiencing symptom re-emergence<br />
– Taking ≤ 800 mg/day levodopa<br />
– Experiencing no dyskinesia<br />
• When initiating Stalevo in a patient currently treated with<br />
levodopa/benserazide, discontinue dosing of levodopa/benserazide the<br />
previous night and start Stalevo the next morning<br />
<strong>Levodopa</strong>/carbidopa Switch Stalevo dose<br />
50 mg<br />
50 mg<br />
100 mg<br />
100 mg<br />
+ 150 mg<br />
150 mg<br />
Stalevo comes in three convenient dose strengths<br />
• Each strength has a 4:1 ratio of levodopa to carbidopa, plus 200 mg of<br />
entacapone<br />
• The only way to provide dopa-decarboxylase and catechol-Omethyltransferace<br />
inhibition in a single tablet formulation<br />
• When initiating Stalevo in a patient currently treated with<br />
levodopa/benserazide, discontinue dosing of levodopa/benserazide the<br />
previous night and start Stalevo the next morning