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Levodopa - epgonline.org

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ENT416_NURSES LEAVEPIECE.qxd 2/10/06 14:08 Page 14<br />

Upgrading to Stalevo ®<br />

• Patients can be switched directly to an equivalent dose of levodopa if<br />

they are:<br />

– Experiencing symptom re-emergence<br />

– Taking ≤ 800 mg/day levodopa<br />

– Experiencing no dyskinesia<br />

• When initiating Stalevo in a patient currently treated with<br />

levodopa/benserazide, discontinue dosing of levodopa/benserazide the<br />

previous night and start Stalevo the next morning<br />

<strong>Levodopa</strong>/carbidopa Switch Stalevo dose<br />

50 mg<br />

50 mg<br />

100 mg<br />

100 mg<br />

+ 150 mg<br />

150 mg<br />

Stalevo comes in three convenient dose strengths<br />

• Each strength has a 4:1 ratio of levodopa to carbidopa, plus 200 mg of<br />

entacapone<br />

• The only way to provide dopa-decarboxylase and catechol-Omethyltransferace<br />

inhibition in a single tablet formulation<br />

• When initiating Stalevo in a patient currently treated with<br />

levodopa/benserazide, discontinue dosing of levodopa/benserazide the<br />

previous night and start Stalevo the next morning

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