Febrile Neutropenia

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Granulocyte colony-stimulating factor (G-CSF) and neutrophil production Endogenous G-CSF 324" 234" 34" Stem cells Neutrophil progenitors Precursor cells Post-mitotic cells Response is greater and more rapid than seen with endogenous G-CSF alone Therapeutic G-CSF 4 !$(% ( ++& +D+
G-CSF reduces FN incidence 7%5'$1!"#$ $ $ ! "8 "! "#'0 - "# " ! "#'0 - - - - %"!/0%,1 +2 3 ' """!/0%,1 + 23 %"!/0%,1 + 23 - - - - - - '4 55! ")6 #5! ")6+ ## ") ") %"!! "!!" !$(69 2 69 2& )' & /
Page 1 and 2: Febrile Neutropenia An ‘A-Z’ of
Page 3 and 4: Grading neutropenia !) * +
Page 6 and 7: Clinical presentation of infection
Page 8 and 9: Impact on chemotherapy delivery: Do
Page 10 and 11: Summary Neutropenia is a common
Page 12 and 13: Risk factors for FN Treatmentrelate
Page 14 and 15: Patient-related and other risk fact
Page 18 and 19: Side effects of G-CSFsG Mild/mode
Page 20 and 21: Febrile neutropenia Managing febril
Page 22 and 23: The impact of infection in patients
Page 24 and 25: Vital signs of SIRS Two or more of
Page 26 and 27: Clinical pathway to manage neutrope
Page 28 and 29: The goal is to minimise risk of inf
Page 30 and 31: Patient and family education: Focus
Page 32: Summary Febrile Neutropenia is

Febrile Neutropenia

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