Febrile Neutropenia

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The impact of infection in patients with cancer Severe sepsis 9.8% higher risk for sepsis than non-cancer patients Incidence higher in haematological malignancies Hospital mortality is higher Accounts for up to 10% of cancer deaths ( local data) Accounts for 4.9% of cancer hospitalisations but 14% of costs Implications for management of FN Implications for prevention of FN 5 &F("
$ ! SIRS Sepsis Systemic Inflammatory Response Syndrome (SIRS), the body’s response to a variety of severe clinical insults which may not be infection Systemic inflammatory response to infection "$"" $% "%7 Sepsis with acute organ dysfunction or hypoperfusion, or hypotension 1 A subset of severe sepsis with hypotension despite adequate fluid resuscitation along with the presence of perfusion abnormalities that may include lactic acidosis, oliguria, or alteration of mental status 1 5
Page 1 and 2: Febrile Neutropenia An ‘A-Z’ of
Page 3 and 4: Grading neutropenia !) * +
Page 6 and 7: Clinical presentation of infection
Page 8 and 9: Impact on chemotherapy delivery: Do
Page 10 and 11: Summary Neutropenia is a common
Page 12 and 13: Risk factors for FN Treatmentrelate
Page 14 and 15: Patient-related and other risk fact
Page 16 and 17: Granulocyte colony-stimulating fact
Page 18 and 19: Side effects of G-CSFsG Mild/mode
Page 20 and 21: Febrile neutropenia Managing febril
Page 24 and 25: Vital signs of SIRS Two or more of
Page 26 and 27: Clinical pathway to manage neutrope
Page 28 and 29: The goal is to minimise risk of inf
Page 30 and 31: Patient and family education: Focus
Page 32: Summary Febrile Neutropenia is

Febrile Neutropenia

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