Standard Annual Report - Neonatal European Information System

EuroNeoNet Annual Report for VLGAI 

& 

Individual Report for Each Unit Practicipating 

in the EuroNeoNet Project 

YEAR 2010 

October 2012

EuroNeoNet 

Annual Report for VLGAI 

INDEX 

1 METHODOLOGICAL INTRODUCTION. ..................................................... 3 

2 DATABASE ELIGIBILITY CRITERIA. ......................................................... 7 

3 INTRODUCTION. ........................................................................................ 8 

4 GENERAL DATA. ..................................................................................... 10 

4.1 ENS Project Participating Units. ......................................................... 10 

4.2 Sample Size ....................................................................................... 11 

5 RESULTS .................................................................................................. 12 

5.1 Deaths in Delivery Room description ................................................. 12 

5.2 2010 Cohort General Description: Admitted babies. .......................... 21 

6 RESULTS. ................................................................................................. 32 

6.1 Multiple Gestation Rate ...................................................................... 32 

6.2 Prenatal Steroids Rate. ...................................................................... 38 

6.3 Caesarean section Rate. .................................................................... 43 

6.4 Resuscitation in Delivery Room rate. ................................................. 48 

6.5 Surfactant at any Time Rate. ............................................................. 53 

6.6 Surfactant within the First hour of Life Rate. ...................................... 58 

6.7 RDS Rate. .......................................................................................... 63 

6.8 Early Sepsis Rate............................................................................... 69 

6.9 Pneumothorax Rate. .......................................................................... 75 

6.10 PIVH (Grades III or IV) Rate. ............................................................. 81 

6.11 NEC Rate. .......................................................................................... 87 

6.12 Focal Gastrointestinal Perforation Rate. ............................................ 93 

6.13 ROP (Grades >=3)Rate. .................................................................... 99 

6.14 O 2 on day 28 Rate. ........................................................................... 105 

6.15 O 2 on week 36 Rate. ........................................................................ 111 

6.16 Late Bacterial Sepsis Rate. .............................................................. 117 

6.17 Steroids for CLD Rate. ..................................................................... 123 

6.18 Cystic PVL Rate. .............................................................................. 128 

6.19 Mortality Rate. .................................................................................. 134 

7 LENGTH OF STAY ANALYSIS FOR VLGAI DISCHARGED TO HOME. 143 

7.1 Sample Size ..................................................................................... 143 

7.2 Lenght of stay (days) description ..................................................... 144 

8 ANNEX .................................................................................................... 147 

8.1 Delivery Room Deaths Description .................................................. 148 

8.2 Demographic Individual Data ........................................................... 149 

8.3 Main Results .................................................................................... 156 

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1 METHODOLOGICAL INTRODUCTION. 

A fundamental base for the individual analysis of Neonatology Units is the 

comparison of basic indicators. The objective is to identify areas that could 

improve, help to set priorities and document different results in health, between 

two or more Units. 

Crude mortality or morbidity or other event rates, are useful general measures 

in the comparative analysis raised above. On the other hand, its use can be 

inappropriate when the different populations studied are not comparable by 

reason of gestational age, birth weight, sex, socio-economic status or other 

factors that can influence the crude rates magnitude and its interpretation. This 

type of phenomenon is called confounding effect (1,2,3). 

To deal with the confounding effect, the use of specific rates determined by 

well-defined subgroups is a procedure widely spread in this type of 

comparisons. However, although these specific rates permit study the 

behaviour of health events and compare different Units in a more accurate way, 

the problem appears when the number of subgroups defined is big (4). In these 

cases, to calculate the specific rates spends a lot of time because of the 

number of operations needed. If sample size for each group is small the specific 

rates con become imprecise. 

Standardisation of rates is a classic epidemiological method that minimises the 

confounding effect of factors that are assumed to behave in a different way in 

each population studied. It also provides a summary measure, which is easily 

understood, and in particular, helpful to those who need a health situation 

synthetic index. 

In our case the factor most frequently used, is birth weight. Standardisation can 

be used when mortality comparisons between Units are done, because birth 

weight structure has a huge impact on the absolute risk a baby has. 

There are two main approaches to standardisation. The first uses as the 

standard a population distribution (direct method), and the second, a set of 

specific rates (indirect method). 

In the direct method, the expected rate for the Units studied is calculated 

assuming its distribution is the same to an established one according to the 

confounding item. The population used is called “Standard” and its subgroups 

correspond to the confounding item. The expected rate per Unit is calculated by 

applying the specific rate for the subgroups of the Standard population to the 

Units populations. 

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Indirect Method. 

The approach in the indirect method is completely different to the one in the 

direct method. Instead of using a standard population, Standard specific rates 

(or reference rates) are applied to the populations compared, according to the 

confusor item. The result of this is the expected number of cases for each Unit 

and subgroup. If the observed number of cases is divided by the expected 

number of cases in each Unit and subgroup, the Standardised 

Mortality/Morbidity Rate (SMR) is obtained. 

This rate permits the comparison between each Unit studied with the population 

whose specific rates have been considered as standard. 

Conclusions can be made only by calculating and observing the SMR. If this 

rate is above 1 (o 100 if is treated as a percentage) the mortality risk in the 

observed population is greater than the one in the standard population 

supposing the same experience and risk for the observed population than for 

the standard one. On the other hand, if the SMR is under 1 (o 100), the 

mortality risk in the observed population is lower than the expected in the 

reference population. 

In addition indirect method adjusted rates can be calculated multiplying the row 

rate of each population by its SMR (4). As in the direct method, a unique value 

is obtained for each population so differences in the population distributions are 

considered. 

SMR are easily calculated and provide relative risk estimation between the 

standard population and the one studied. These are frequently used in 

epidemiology to compare different groups. 

However, we have to take in account that in some situations these comparisons 

are not suitable. For instance: when the rates in the studied groups and the 

standard groups according to the classes of the confusor item are not 

homogeneous (7). Above this, the comparisons between each group and the 

reference population is always is outstanding. 

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In the next table an example using the indirect standardisation method is 

shown. 

Example. 

Crude mortality rate in the NU (Neonatal Unit) was of 16,4 per 100 VLBWI. The 

aim is to study if the differences in mortality (o mortality risk) between the Unit 

studied and the whole set according to the indirect method are statistically 

significant. For this, the following data are needed. 

 

 

 

The mortality specific rates according to the subgroups in the 

confusor item in the standard population. 

The UN population divided by groups of birth weight (confounding 

item). 

The total observed number of deaths in the UN. 

First, the expected number of deaths must be calculated multiplying the 

standard rates to the number of cases in each subgroup of the UN population. 

(Column (3) = (1) * (2)/100). Then we must add all the expected deaths 

calculated for each subgroup, and also the observed deaths. 

The SMR is obtained by dividing the total number of observed deaths by the 

total number of expected deaths. 

Mortality specific rates 

according to birth 

weight groups (1) 

NU population (i) 

(2) 

Observed Deaths 

(3) 

Expected deaths in (i) 

< 501 g 75 - - - 

501 - 750 g 52,1 10 6 5,21 

751 - 1000 g 23,4 18 4 4,21 

1001 - 1250 g 9,9 21 1 2,08 

1251 - 1500 g 4,9 24 1 1,18 

Total 73 12 12,68 

SMR for UN = 12/12,68 = 0,95. 

SMR (%) for UN = (12/12,68) * 100 = 95%. 

The value of the SMR (95%) means that the mortality risk in the Unit 

studied is a 5% less than the expected, had the studied Unit had the 

standard population specific mortality rates across the different strata of 

birth weight (confounder in this case). In conlcusion the Unit has a 

sloghtly lower standardised mortality rate than expected, Ussually 95% CI 

are estimated for the SMR as a measure of its precision and to check 

whether the "null value" (SMR=1) is included in the interval. 

The 95% CI permit us say, that there is a 95% of probability that the SMR 

is between 0,41 and 1,49. As the "null value" (1) is included we have no 

evidence that this Unit's SMR is significantly different fromn the reference 

population's SMR. 

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As neonates’ population is affected not only by birth weight, it has been 

considered to apply more than one confounding item, and therefore try to solve 

the homogeinity problem. At least standardization has been done by birth 

weight, gestational age and gender. For some of the outcomes predictive items 

resulting form a logistic regression over more than 30.000 thousand registers 

have been used as confounding items. 

To resume, adjusted rates permit more valid comparisons between populations, 

which will help stablishing priorities between groups. 

Furthermore, this report not only intends to allow comaprisons between units 

studied, but to draw a picture of the general performing of the unit in realtion to 

the whole set of units. 

A way of establishing the position that a Unit has inside the set of Units studied 

is to calculate the percentile corresponding to each Unit according to the 

studied item. This percentile shows the position but not the difference in 

magnitude between Units in the item. A 95 percentile in mortality is a negative 

result. If differences between units are very small, that is, there is very small 

variability; the SMR that is in position 95 probably differs from the previous one 

in only some decimals. 

To be able to quantify the position reached by each Unit, the typified score for 

SMR is calculated. In this report, these are calculated in such a way that a 

result above 0 is a positive result and the intensity of it is given by the score 

itself. The length of the bar shows how positive/negative the result is. The 

bigger the score is, the better the result is; and the smaller (negative score), the 

worse is. If the stick crosses the discontinuous line (+/- 1.96), the result will be 

statistically significant. 

References: 

1. Last J. Dictionary of Epidemiology, Fourth Edition. New York, New York: Oxford University 

Press. 2001 

2. Jenicek M, Cléroux R. Epidemiología: Principios, Técnicas y Aplicaciones. Barcelona, 

España: Salvat Editores. 1987. 

3. Gordis L. Epidemiology. Philadelphia, PA: W.B. Saunders Company. 1996. 

4. Pagano M, Gauvreau K. Principles of Biostatistics. Belmont, California: Wadsworth, Inc. 

1993. 

5. Kramer S. Clinical Epidemiology and Biostatistics. A primer for Clinical Investigators and 

Decision-makers. Berlin Heidelberg, German: Springer_verlag. 1998. 

6. Waterhouse J et al. (eds.). Cancer incidence in five continents. Lyon, France: IARC. 1976. 

7. Szklo M, Nieto J. Epidemiology, Bwyond the basics. Gaithersburg, MD: Aspen Publishers 

Inc. 2000 

8. http:// www.paho.org/Spanish/SHA/be_v23n3-cover.htm 

Tomado del Boletín Epidemiológico, Vol. 23 No. 3, septiembre 2002. 

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2 DATABASE ELIGIBILITY CRITERIA. 

Any infant born alive at your hospital, whether or not was admitted to your 

NICU, should be reported if his/her: 

Birth Weight (BW) is less than 1501 g 

OR 

Gestational Age (GA) is less than 32 wks (31 + 6 days inclusive). 

All livebirths must be reported, no matter if his/her gestational age is below 22 

weeks or the birth weight is below 401g. 

All outborn infants of same BW and GA as above, admitted to any location in 

your hospital within 28 days of birth should also be included, only if the baby 

has never been discharged home. 

Outborn babies admitted to the Neonatal Unit after the 28th day of life, should 

not be included in the Database, since by international definitions those babies 

are no longer “newborn” but “infants”. 

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3 INTRODUCTION. 

A statistical analysis of the VLBW/VLGA infants cohort data (defined in 

protocol), for the cases sent before September of 2012 is performed in this 

report. These cases correspond to babies born in Units shown in Table 4.1. 

The Report consists on two main parts. The first part is common to every unit 

that has collaborated with data for the cohort analysed (Sections 5 to 7). The 

second part (Section 8) changes form unit to unit. Each unit will receive an 

analyses only for their own data (condifentiallity is assured). 

The common part is divided in three sections, a general descriptive analysis 

section (#5), a benchmarking section (#6) and a length of stay analysis section 

(#7). 

General descritptive analysis includes a description of babies died in the 

delivery room (section 5.1) in terms of counts and percentatges, means, 

medians, standards deviations and percentiles depending on the nature of the 

item described. All items collected for babies died in deliver room are described 

including major birth defects description and possible causes of death. (After this 

section, babies died in delivery room are excluded from the rest of the analyses done in 

the report). 

The main population is also decribed in section 5.2, including perinatal risks 

factors, interventions, diagnoses and morbi-mortality outcomes. At the end of 

the section row global rates and stratified rates by birth weight groups and 

gestational age gropus for several items have been calculated. 

Once the population has been described, a univariate analysis of each item has 

been done. These analyses permit to establish the position that each Unit 

occupies compared with the other Units, and also the position in relation to the 

whole set (Point 6: Benchmarking). The statistical procedure has been 

described in the Methodological Introduction (Point 1). 

The analysis done in previous sections, shows which is the position that a Unit 

occupies in relation to the whole set of Units for items considered relevant. In 

the next section (Point 7), the total stay of VLBW/VLGA inafants that were 

discharged to home have been analysed. 

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Finally, once all the items considered relevant according to the study objectives 

have been analysed, a more accurate description of these and other items for 

each Unit separately, has been done (Point 8: Annex.). Firstly demographic 

items are described, including prenatal care, Bag/Mask in delivery room and so 

on… Secondly, in the next section, items related with Morbimortality have been 

analysed, and finally, a section called Main Results has been included. This 

section gives a global view of which is the position of each Unit inside the whole 

set of Units. On the one hand, this analysis shows the position of the Unit (Point 

8.3.1), and on the other hand, it quantifies this position (Point 8.3.2). This 

section tries to provide a summarised picture of the Unit's condition so just 

taking a short look to the graph you can get a grasp of the global results for the 

studied Unit. 

To distinguish one Unit from another, a code has been assigned to each. We 

will provide each Unit ONLY its code at the same time as this report is 

delivered. This way the confidentiality of data is preserved. 

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4 GENERAL DATA. 

4.1 ENS Project Participating Units. 

The following list corresponds to the Units that have sent complete and verified 

data for the year 2010, before May the 31 st of 2012. 

Table 4.1 

Type Unit Responsible for the Project Country City 

Associated Klinische Abteilung für Neonatologie Berndt Urlesberger Austria Graz 

Collaborative LKH Klagenfurt Raimund Kraschl Austria Klagenfurt 

Collaborative General Hospital of Leoben Anna Trinkl Austria Leoben 

Collaborative Chirec (Edith Ravell) Mark Flansh Belgium Bruxelles 

Collaborative CHU Saint Luc Christian Debauche Belgium Bruxelles 

Collaborative CHU Saint Pierre Dominique Haumont Belgium Bruxelles 

Collaborative CHU de Chraleroi Eric Cavatorta Belgium Charleroi 

Collaborative CHU Saint Vincent Pierre Maton Belgium Chetien 

Collaborative CHU Ziekenhuis Oost-Limburg Claire Theyskens Belgium Genk 

Collaborative CHU de la Citadelle Jacques Rijo Belgium Liége 

Collaborative CHU Tivoli Genevieve Malfilatre Belgium Tivoli 

Collaborative General Faculty Hospital in Prague Richard Plavka Czech Republic Bohemia 

Associated Oulu University Hospital Mikko N. Hallman Finland Oulu 

Collaborative Hospital Edouart Heriot Olivier Claris France Lyon 

Collaborative Hospital de la Concepcion Umberto Simeoni France Marseille 

Associated University Children's Hospital Helmut Hummler Germany Ulm 

Collaborative Ginekologiczno Polozniczy Szipital Kliniczny Janusz Gadzinowski Poland Poznan 

Collaborative Portugal Neonatal Network Alexandra Almeida Portugal Portugal 

Associated Spanish Neonatal Network (SEN 1500) Josep Figueras Spain Spain 

Collaborative Swedish National Network (PNQ) Gunnar Sjörs/Stellan Hakansson Sweden Sweden 

Collaborative Hospital of Aarau --- Switzerland Aarau 

Collaborative Hospital of Basel --- Switzerland Basel 

Collaborative Inselspital Children Hospital Olaf Ahrens Switzerland Berne 

Collaborative Hospital of Chur --- Switzerland Chur 

Collaborative Hospital of Geneva --- Switzerland Geneve 

Collaborative Hospital of Lausane --- Switzerland Lausane 

Collaborative Hospital of Luzern Thomas Berger Switzerland Luzern 

Collaborative Hospital of St. Gallen --- Switzerland St. Gallen 

Collaborative Neonatology Clinic Hans Ulrich Bucher Switzerland Zurick 

Collaborative Meral Medical Faculty Rahmi Ors Turkey Selcuk 

Associated Liverpool Womens Hospital Michael Weindling UK Liverpool 

Associated North Ireland Network Stan Craig UK UK 

To preserve units’ confidentiality the number of cases and percentage that each 

unit represent inside the total of infants born in 2010 is not described. 

Each year, more units, regional and national networks are interested in the 

project. This means that the number of units collaborating by country is 

increasing, being mandatory the need to describe each country’s 

representatitvity. 

For 2010 data, a 33.5% of infants were born in Spain, a 14.6% in Portugal, a 

10.7% in Switzerland, a 9.2% in Sweden, a 8.1% in the UK, a 7.1% in Belgium 

and the remaining 16.8% in the other ENN countries. 

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4.2 Sample Size 

The total number of cases received for 2010 VLGAI cohort for Units that have 

sent complete and verified data were 7,540. 

2011 Cohort 

Sample Size 

N = 7,540 

Died in DR 

N = 103 

(1.4%) 

Admitted to the NICU 

N = 7,437 (98.6%) 

Home 

N = 4,903 

(65.9%) 

Trasnferred 

N = 1,748 

(23.5%) 

Died 

N = 766 

(10.3%) 

Still 

Hospitalized 

N = 20 (0.3%) 

The purpose of this report is to help units to perform better by comparing results 

to other units pertaining the network and to the whole set of data. Therefore, 

comparisons must be done over reliable data and moreover, restrictions must 

be applied, if not results would be meaningless. 

For that reason, data is divided, firstly, in babies died in delivery room and 

babies admitted to the NICU. 

In 2010 cohort a 1.4% of babies died in delivery room. That is, 103 babies. 

These, will be analysed in the following section, separately from babies 

admitted to the NICU. (Section 5.1 Deaths in delivery room description). 

General analysis (benchmarking) will be performed over admitted babies in 

Section 6. A 65.9% of babies admitted to the NICU were discharged home. 

Length of stay will be analysed globaly and for each unit for those babies in 

Secion 7. 

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5 RESULTS 

5.1 Deaths in Delivery Room description 

Data recorded for deaths in delivery room is smaller than for admitted babies. 

Birth weight, gestational age, birth length, birth head circumference, Prenatal 

Care, Prenatal Steroids, Mode of delivery, Gender, Multiple birth, Major Birth 

Defects, Apgar Scores, delivery room resuscitation and need for surfactant are 

recorded, together with information on death. All these information is described 

for dead in delivery room babies below. 

Birth Weight 

Mean birth weight for 2010 cohort babies died in delivery room has been of 

640.1 g. Extreme values are those under 307 g., and above 1,392. (Percentile 5 

and Percentile 95). 

Birth weight 

Mean (SD) 640.1 (273.4) 

95% CI (Mean) (586.6;693.5) 

Med [Q 1 ,Q 3 ] 580 [480;710] 

Min-Max 212 – 1,800 

P 5 -P 95 307-1,392 

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Note: Only analysed deaths in Delivery Room.

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Gestational Age 

Median gestational age for 2010 cohort babies died in delivery room has been 

of 23 weeks. Extreme values are those under 21 weeks, and above 30.8 weeks 

(Percentile 5 and Percentile 95). 


Mean (SD) 23.9 (2.6) 

95% CI (Mean) (23.4;24.4) 

Med [Q1,Q3] 23 [22 ; 24] 

Min-Max 20-33 

P5-P95 21-30.8 


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Birth Length and Birth Head Cirumference 

Median birth length for 2010 cohort babies dien in delivery room has been of 

3.31 cm. Extreme values are those under 26.8 cm, and above 37.9 cm 

(Percentile 5 and Percentile 95). 

For birth head circumference median was of 22.6 cm. Extreme values are those 

under 19.3 cm, and above 27 cm (Percentile 5 and Percentile 95). 

Birth length 

Birth head 

circumference 

Mean (SD) 31.3(3.3) 22.6 (2.1) 

95% CI (Mean) (30.2;32.5) (21.9;23.3) 

Med [Q 1 ,Q 3 ] 31 (29.2;32) 22.5(21-23.5) 

Min-Max 26-43 19-27 

P 5 -P 95 26.8-37.9 19.3-27 


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Apgar Scores 

For babies died in delivery room, 1-min Apgar Score mean has been of 1.6, and 

5-min score mean of 1.4. None of them scored more than 5. 

1-min Apgar 

Score 

5-min Apgar 

Score 

Mean (SD) 1.6 (1.4) 1.4 (1.5) 

95% CI (Mean) (1.3;1.9) (1.1 , 1.8) 

Med [Q 1 ,Q 3 ] 1 [1;2] 1 [1,2] 

Min-Max 0 -7 0 – 9 

P 5 -P 95 0 -5 0 - 5 


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Perinatal Factors 

For died in delivery room population, more than half were male (54.9%). A 

23.3% of babies were born by caesarean section, a 18.4% were multiple, a 

23.5% of all babies received some prenatal steroids and a 98.7% received 

prenatal care. 

N % 

Male 56 54.9 

Multiple Gestation 19 18.4 

Caesarean Section 24 23.3 

Prenatal Steroids (Inc. + Compl.) 20 23.5 

Prenatal Care 75 98.7 

Gender 

54.9% 

Multiple Gestation 

18.4% 

Caesarean Section 

23.3% 

Prenatal Steroids (Inc. + Compl.) 

23.5% 

Prenatal Care 

98.7% 


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Resuscitation in Delivery Room 

A 21.6% of babies died in delivery room needed some kind of resuscitation 

(excluding oxygen). Oxygen rate was of 24.5%. 

Delivery Room Resuscitation N % 

Oxygen 25 24.5 

Any Non Aggressive Positive Ventilation 18 17.6 

Endotracheal Intubation 17 16.7 

Adrenaline/Epinephrine 7 6.9 

Cardiac Compression 7 6.9 

Any Resuscitation in Delivery Room (ex. O 2 ) 22 21.6 

Oxygen 

24.5% 

Non Aggressive Positive Ventilation 

17.6% 

Endotracheal Intubation 

16.7% 

Adrenaline/Epinephrine 

6.9% 

Cardiac Compression 

6.9% 

Any Resuscitation in DR (Ex. O 2 ) 

21.6% 


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Major Birth Defects 

A 21.4% of babies died in delivery room had a major birth defect; a 91.7% had 

one and an 8.3% two. These 22 babies summed 24 congenital abnormalities. 

Most common birth defect was skeletal dysplasia (12.5%). 

Major Birth Defect N % 

Skeletal dysplasia 3 12,5 

Anencephaly and similar malformations 2 8,3 

Bilateral renal agenesis 2 8,3 

Down s syndrome 2 8,3 

Hydranencephaly 2 8,3 

Hypoplastic left heart syndrome 2 8,3 

Double outlet right ventricle 1 4,2 

Edwards' syndrome and Patau's syndrome 1 4,2 

Holoprosencephaly 1 4,2 

Meningomyelocele 1 4,2 

Transposition of the great vessels 1 4,2 

Other CNS Defects 2 8,3 

Other GI Defects 2 8,3 

Other defects of metabolism and other origin 1 4,2 

Other GU Defects 1 4,2 

Total 24 100 

Need for Surfactant 

Only two babies that died in delivery room needed surfactant. One of them 

received one surfactant dose at 5 minutes of life, and the other a single dose at 

3 hours and 40 minutes of life. 


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Cause of death 

Cause of death was only specified for 59 babies of 103 that died in delivery 

room. Most frequent cause was Extreme Prematurity (28.8%), followed by 

Congenital Malformations (27.1%). 

Cause of Death N % 

Extreme Prematurity 17 28,8 

Congenital Malformation 16 27,1 

Respiratory Failure 7 11,9 

Sepsis 2 3,4 

Severe Pulmonary Immaturity 2 3,4 

Chorioamnionitis 1 1,7 

Fetal Ascites Hydrops 1 1,7 

Neurological 1 1,7 

Unknown 1 1,7 

Other 11 18,6 

Total 59 100 

Extreme Prematurity 28.8% 

Congenital Malformations 27.1% 

Respiratory Failure 11.9% 

Sepsis 3.4% 

Severe Pulmonary Immaturity 3.4% 

Chorioamnionitis 1.7% 

Feta Ascites Hydrops 1.7% 

Neurological 1.7% 

Unknown 1.7% 

Other 18.6% 


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An autopsy was done to 49.3% of babies and therapeutic efforts were limited to 

an 88.9% of babies died in delivery room. 

N % 

Autopsy 37 49.3 

Therapeutic efforts limited 72 88.9 


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5.2 2010 Cohort General Description: Admitted babies. 

Total number of admitted babies in EuroNeoNet NICU’s for 2010 cohort, has 

been of 7,437. 

5.2.1 Perinatal Risk Factors 

Birth Weight 

Mean birth weight for 2010 babies admitted to the NICU has been of 1,179.3 g. 

Extreme values are those under 613.6 g., and above 1,720g. (Percentile 5 and 

Percentile 95). 

Birth weight 

Mean (SD) 1,179.3 (342.2) 

95% CI (Mean) (1,171.5;1,1187) 

Med [Q 1 ,Q 3 ] 1,200 [920;1,420] 

Min-Max 227 -3,064 

P 5 -P 95 613.6 - 1,720 


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Note: Excluded babies died in Delivery Room. Analyzed population: Admitted babies.

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5.2.2 Gestational Age 

Median gestational age for 2010 cohort has been of 29 weeks. Extreme values 

are those under 24 weeks, and above 33 weeks (Percentile 5 and Percentile 

95). 


Mean (SD) 29.1 (2.7) 

95% CI (Mean) (29 , 29.1) 

Med [Q1,Q3] 29 [27 ; 31] 

Min-Max 21 - 41 

P5-P95 24 - 33 


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5.2.3 Apgar Scores 

1-min Apgar Score mean has been of 6.2, and 5-min score mean of 8. 

1-min Apgar 

Score 

5-min Apgar 

Score 

Mean (SD) 6.2 (2.5) 8 (2) 

95% CI (Mean) (6.13 , 6.24) (7.93 , 8.02) 

Med [Q 1 ,Q 3 ] 7 [5;8] 8 [7,9] 

Min-Max 0 – 10 0 – 10 

P 5 -P 95 1 – 9 4 - 10 


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5.2.4 Perinatal Factors 

More than half of the population were male (51.4%). A 70.8% of babies were 

born by caesarean section and a 33.1% were multiple. 

Regarding to prenatal care and prenatal steroids, a 85.6% of babies received 

prenatal care and a 84.5% received prenatal steroids (incomplete or complete). 

N % 

Male 3,819 51.4 

Multiple Birth 2,458 33.1 

Caesarean Section 5,257 70.8 

Prenatal Steroids 6,203 84.5 

Prenatal Care 5,049 85.6 

Gender 

51.4% 

Multiple Birth 

33.1% 

Caesarean Section 

70.8% 

Prenatal Steroids 

84.5% 

Prenatal Care 

85.6% 


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5.2.5 Respiratory System 

A 64.6% of babies admitted to the NICU received some kind of resuscitation in 

Delivery Room, excluding Oxygen. 

Need for surfactant rate was of 48.3% and surfactant was administrated within 

the first hour of life in a 27.5% of babies. 

Respiratory Distress syndrome was diagnosed in a 65.1% of babies admitted to 

the NICU. 

N % 

Resuscitatin in DR 4,790 64.6 

Surfactant at any time 3,590 48.3 

Surfactant within the first hour of life 1,985 27.5 

RDS Diagnose 4,752 65.1 

Resuscitation in Delivery Room 

64.6% 

Surfactant at any time 

48.3% 

Surfactant within the 1 st hour of life 

48.3% 

RDS 

65.1% 

0 20 40 60 80 


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5.2.6 Early Bacterial Sepsis 

Early Bacterial Sepsis was diagnosed in a 3.4% of babies admitted to the NICU. 

Most frequent pathogen was Escherichia coli (22.7%), followed by Group betahemolytic 

streptococcus (13.3%). Pathogen type wasn’t specified for 45 of 

babies that had an early bacterial sepsis. 

N % 

Early Bacterial Sepsis 248 3.4 

Early Bacterial Sepsis Pathogen N % 

Escherichia coli 46 22,7 

Group B beta-hemolytic streptococcus 27 13,3 

Staphylococcus epidermidis 25 12,3 

Enterococcus faecalis (Streptococcus faecalis) 17 8,4 

Staphylococcus aureus 12 5,9 

Listeria monocytogenes 9 4,4 

Klebsiella pneumoniae 7 3,4 

Cándida albicans 4 2 

Serratia marcescens 4 2 

Citrobacter species 3 1,5 

Enterobacter cloacae 1 0,5 

Moraxella spp 1 0,5 

Neisseria meningitidis 1 0,5 

Ralstonia species 1 0,5 

Stenotrophomonas maltophilia 1 0,5 

Streptococcus pneumoniae 1 0,5 

Ureaplasma urealiticum 1 0,5 

Other Candida spp (C.parapsilosis and othyer) 1 0,5 

Other Streptococcus spp (S. group A, S. group D and other) 3 1,5 

Other Virus 1 0,5 

Other 37 18,2 

Total 203 100 


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5.2.7 Diagnoses 

A 3.6% of babies admitted to the NICU were diagnosed of Pneumothorax, a 

5.5% of NEC and a 1.8% of Focal Gastrintestinal Perforation. 

N % 

Pneumothorax Diagnose 270 3.6 

NEC Diagnose 404 5.5 

Focal Gastrointestinal Diagnose 129 1.8 

Pneumothorax 

3.6 % 

Necrotizing Enterocholitis 

5.5% 

Focal Gastrointestinal Perforation 

1.8% 


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5.2.8 Morbi-Mortality 

Mortality rate for babies admitted to the NICU was of a 10.3%. 

BPD was diagnosed in a 16.8%, severe PIVH in a 7.8%, Cystic PVL in a 4.4% 

and a 23.3% had a late bacterial sepsis. 

N % 

Severe PIVH (Grades III-IV) 520 7.8 

Oxygen on week 36 (BPD) 640 16.8 

Late Bacterial Sepsis 1,721 23.3 

Cystic PVL 285 4.4 

Overall Mortality 766 10.3 

PIVH(Grades III or IV) 

7.8% 

Oxygen on week 36 (BPD) 

16.8% 

Late Bacterial Sepsis 

23.3% 

Cystic PVL 

4.4% 

Mortality 

10.3% 


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From the 1,721 babies that had a late bacterial sepsis, only a 57.6% (992) 

registered which pathogen caused the infection. 

Number of Infections’ episode N % 

One episode 809 81.6 

Two episodes 128 12.9 

Three episodes 55 5.5 

An 81.6% had only one sepsis episode, a 12.9% two and a 5.5% three. That 

sums 1,230 late sepsis episodes. The most frequent pathogen was 

Staphylococcus epidermidis (45.9%) followed by Stahylococcus aureus (8.8%). 

Late Bacterial Sepsis Pathogen N % 

Staphylococcus epidermidis 565 45,9 

Staphylococcus aureus 108 8,8 

Klebsiella pneumoniae 98 8 

Escherichia coli 71 5,8 

Enterococcus faecalis (Streptococcus faecalis) 64 5,2 

Enterobacter cloacae 49 4 

Serratia marcescens 38 3,1 

Group B beta-hemolytic streptococcus 29 2,4 

Pseudomonas aeruginosa 29 2,4 

Cándida albicans 28 2,3 

Candida parapsilopsis 10 0,8 

Proteus mirabilis 5 0,4 

Other Streptococcus spp 5 0,4 

Stenotrophomonas maltophilia 5 0,4 

Acinetobacter spp 4 0,3 

Other Enterococcus spp 4 0,3 

Other Serratia spp 4 0,3 

Other Pseudomonas 2 0,2 

Oher virus 2 0,2 

Citrobacter species 1 0,1 

Ureaplasma urealiticum 1 0,1 

Clamidia 1 0,1 

Clostridium spp 1 0,1 

Other Klebsiella spp 18 1,5 

Other Candida spp 7 0,6 

Other Enterobacter spp 1 0,1 

Other Proteus spp 1 0,1 

Other 79 6,4 

Total 1230 100 


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5.2.9 Global Results Summary: Risk factors, interventions and general results. 

5.2.9.1 By Birth Weight 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 1251 - 1500 gr. 

> 1500 gr. TOTAL 

Nº % Nº % Nº % Nº % Nº % Nº % Nº % 

Nº of babies recalled 108 1,5 866 11,6 1405 18,9 1709 23 2409 32,4 940 12,6 7437 100 

Male 47 43,5 397 45,8 716 51 864 50,6 1240 51,5 555 59 3819 51,4 

Multiple Gestation 27 25 235 27,1 443 31,6 551 32,2 886 36,8 316 33,6 2458 33,1 

Prenatal Steroids 81 77,1 742 86,9 1206 87,3 1453 86,1 1933 81,4 788 84,1 6203 84,5 

Caesarean Section 66 61,1 540 62,4 1017 72,6 1286 75,3 1775 73,7 573 61 5257 70,8 

Resuscitation in Delivery Area (1) 91 84,3 785 90,9 1149 82 1098 64,5 1164 48,6 503 53,7 4790 64,6 

Surfactant at any time 78 72,2 728 84,2 1027 73,1 821 48,1 697 28,9 239 25,4 3590 48,3 

Surfactant within the first hour of life 57 53,8 512 61,8 631 47,2 431 26 269 11,4 85 9,1 1985 27,5 

RDS Diagnose (2) 83 77,6 740 88,3 1126 82,4 1112 66,8 1152 48,4 539 57,3 4752 65,1 

Early Sepsis 4 3,8 48 5,8 64 4,7 65 3,9 46 1,9 21 2,3 248 3,4 

Mortality 55 50,9 303 35 222 15,8 94 5,5 70 2,9 22 2,3 766 10,3 

Pneumothorax (2) 5 4,6 49 5,7 70 5 44 2,6 72 3 30 3,2 270 3,6 

PIVH (Grades > 0) (3) 32 39 353 45,6 453 35,4 359 23,2 300 14 132 16,2 1629 24,5 

PIVH (Grades III or IV) (3) 12 14,6 163 21,1 162 12,6 99 6,4 62 2,9 22 2,7 520 7,8 

NEC (2) 12 11,2 110 13 116 8,5 91 5,4 55 2,3 20 2,1 404 5,5 

FGP (2) 7 6,5 32 3,8 51 3,7 23 1,4 14 0,6 2 0,2 129 1,8 

ROP (Grades > 0) (4) 22 48,9 282 53,7 371 34,3 219 16,1 135 8,1 22 4 1051 20,1 

Oxygen on day 28 (5) 43 91,5 443 85,4 618 60,1 362 28,6 163 11,2 25 5,9 1654 34,9 

Oxygen on week 36 (6) 15 46,9 203 48,8 222 27,8 123 12,6 64 4,9 13 4,8 640 16,8 

Steroids for CLD (2) 16 17,2 159 20,6 143 11,3 53 3,4 25 1,1 14 1,8 410 6,2 

Cystic PVL (2) 3 3,2 39 4,8 73 5,4 71 4,3 66 2,9 33 3,7 285 4 

Late Sepsis (2) 29 27,9 358 42,1 544 39,1 392 23,1 318 13,3 80 8,6 1721 23,3 

(1) Excluding Oxygen in Delivery Area. (3) Exluded Babies Died in Delivery Room and Without Cranial Imaging Done. (5) Excluded Babies Dischraged Before Day 28 of Life 

(2) Deaths in Delivery Room Excluded. (4) Excluded Babies Died in Delivery Room and Without Retinal Exam Done (6) Excluded Babies Discharged Before Week 36 Adjusted to Gestational Age. 

RDS: Respiratory Distress Syndrome. 

NEC: Necrotizing Enterocholitis 

ROP: Retinopathy of Prematurity. 

PIVH: Periventricular-Intraventricular Haemorrhage. 

FGP: Focal Gastrointestinal Perforation. 

PVL: Periventricual Leukomalacia. 


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5.2.9.2 By Gestational Age. 

< 24 wk. 24 - 25 wk. 26 - 27 wk. 28 - 29 wk. 30 - 31 wk. 

> 31 wk. TOTAL 

Nº % Nº % Nº % Nº % Nº % Nº % Nº % 

Nº of babies recalled 116 1,6 738 9,9 1260 16,9 1732 23,3 2453 33 1138 15,3 7437 100 

Male 63 54,3 387 52,4 655 52 954 55,1 1251 51 509 44,8 3819 51,4 

Multiple Gestation 33 28,4 208 28,2 373 29,6 531 30,7 919 37,5 394 34,6 2458 33,1 

Prenatal Steroids 67 59,8 621 85,2 1078 87,3 1508 87,8 2110 86,6 819 73,7 6203 84,5 

Caesarean Section 23 19,8 355 48,2 877 69,9 1244 71,9 1763 71,9 995 87,4 5257 70,8 

Resuscitation in Delivery Area (1) 101 87,8 704 95,4 1060 84,1 1201 69,6 1298 53,1 426 37,8 4790 64,6 

Surfactant at any time 92 79,3 670 90,8 1000 79,5 996 57,5 753 30,7 79 6,9 3590 48,3 

Surfactant within the first hour of life 71 62,3 508 71,9 643 53,7 472 28,3 260 10,8 31 2,7 1985 27,5 

RDS Diagnose (2) 88 76,5 654 91,7 1083 88 1283 76,2 1378 56,9 266 23,5 4752 65,1 

Early Sepsis 9 8,3 58 8,1 68 5,5 59 3,5 46 1,9 8 0,7 248 3,4 

Mortality 83 71,6 282 38,2 199 15,8 102 5,9 69 2,8 31 2,7 766 10,3 

Pneumothorax (2) 6 5,2 62 8,4 52 4,1 64 3,7 75 3,1 11 1 270 3,6 

PIVH (Grades > 0) (3) 53 63,1 364 55,1 419 36,4 369 23,3 320 14,7 104 10,6 1629 24,5 

PIVH (Grades III or IV) (3) 33 39,3 185 28 149 12,9 91 5,7 48 2,2 14 1,4 520 7,8 

NEC (2) 13 11,3 83 11,6 118 9,6 101 6 64 2,6 25 2,2 404 5,5 

FGP (2) 3 2,6 36 5 46 3,7 23 1,4 18 0,7 3 0,3 129 1,8 

ROP (Grades > 0) (4) 19 65,5 258 60 370 38,1 252 18 129 7,5 23 3,4 1051 20,1 

Oxygen on day 28 (5) 26 96,3 369 88,5 661 72,2 441 33,8 128 8,6 29 5 1654 34,9 

Oxygen on week 36 (6) 8 61,5 142 47,8 238 35,3 145 16,6 71 6,4 36 4,3 640 16,8 

Steroids for CLD (2) 15 12,9 143 21,8 148 13,1 61 4 35 1,6 8 0,8 410 6,2 

Cystic PVL (2) 3 3,3 38 5,5 79 6,5 69 4,1 78 3,3 18 1,7 285 4 

Late Sepsis (2) 33 30 310 42,9 510 40,8 418 24,3 319 13,1 131 11,5 1721 23,3 

(1) Excluding Oxygen in Delivery Area. (3) Exluded Babies Died in Delivery Room and Without Cranial Imaging Done. (5) Excluded Babies Dischraged Before Day 28 of Life 

(2) Deaths in Delivery Room Excluded. (4) Excluded Babies Died in Delivery Room and Without Retinal Exam Done (6) Excluded Babies Discharged Before Week 36 Adjusted to Gestational Age. 

RDS: Respiratory Distress Syndrome. 

NEC: Necrotizing Enterocholitis 

ROP: Retinopathy of Prematurity. 

PIVH: Periventricular-Intraventricular Haemorrhage. 

FGP: Focal Gastrointestinal Perforation. 

PVL: Periventricual Leukomalacia. 


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Annual Report for VLBWI 

6 RESULTS. 

6.1 Multiple Gestation Rate 

Definition: any birth involving more than one infant. 

6.1.1 Multiple Gestation Rate by Birth Weight per Unit. 

The global multiple gestation rate for 2010 cohort has been of 33.1%, with a 

variation of 15.4% and 68.4% within units. 

Unit 

Code 

Multiple Gestation Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

N % N % N % N % N % N % N % 

1 1 100 5 62,5 4 26,7 7 33,3 12 38,7 7 36,8 36 37,9 

2 --- --- --- --- --- --- 1 20 3 42,9 2 22,2 6 24 

3 --- --- 4 25 4 17,4 14 37,8 9 25 10 23,8 41 26,5 

4 2 66,7 2 25 --- --- 3 18,8 8 38,1 4 28,6 19 27,1 

5 1 33,3 6 28,6 7 23,3 11 34,4 9 23,1 11 26,2 45 26,9 

6 1 11,1 4 25 13 38,2 11 40,7 15 34,1 14 33,3 58 33,7 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 16,7 1 11,1 4 80 6 27,3 

9 --- --- --- --- --- --- 3 30 2 13,3 1 14,3 6 16,7 

10 1 100 3 42,9 2 28,6 3 18,8 5 35,7 10 62,5 24 39,3 

11 --- --- 4 30,8 10 40 12 36,4 13 27,7 5 19,2 44 30,3 

12 --- --- 13 23,2 22 27,2 33 33,3 65 41,9 29 33,3 162 33,7 

13 --- --- --- --- --- --- --- --- 4 33,3 --- --- 4 16 

14 1 33,3 5 15,2 10 21,3 29 43,3 48 39 18 35,3 111 34,3 

15 --- --- --- --- 3 13,6 2 28,6 9 25 2 18,2 16 19,3 

16 --- --- --- --- 2 50 2 50 8 42,1 3 27,3 15 37,5 

17 --- --- 3 33,3 5 35,7 7 26,9 13 46,4 6 46,2 34 37,8 

18 --- --- --- --- 2 28,6 7 30,4 8 36,4 4 30,8 21 30,4 

19 --- --- 1 12,5 1 16,7 3 20 5 26,3 6 33,3 16 23,9 

20 --- --- 1 20 6 33,3 2 12,5 9 37,5 7 46,7 25 31,6 

21 --- --- 3 100 1 20 3 27,3 8 44,4 --- --- 15 36,6 

22 --- --- 2 40 4 36,4 4 33,3 4 21,1 5 31,3 19 29,7 

23 --- --- 8 25,8 15 29,4 15 26,3 9 18,8 7 25,9 54 25,1 

24 --- --- 7 26,9 19 33,9 18 36,7 18 43,9 --- --- 62 36 

25 --- --- --- --- --- --- 3 30 4 33,3 --- --- 7 28 

26 --- --- 7 36,8 5 35,7 8 57,1 15 68,2 --- --- 35 50,7 

27 --- --- --- --- 3 25 5 55,6 8 38,1 --- --- 16 33,3 

28 --- --- --- --- 6 75 1 50 6 66,7 --- --- 13 68,4 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 5 50 5 25 7 63,6 12 36,4 --- --- 29 39,2 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 50 2 33,3 1 14,3 4 50 2 22,2 --- --- 10 31,3 

33 1 25 7 38,9 16 51,6 17 50 25 48,1 1 100 67 47,9 

34 1 100 1 16,7 3 25 2 20 9 69,2 --- --- 16 38,1 

35 --- --- 3 50 3 37,5 1 33,3 --- --- --- --- 7 28 

36 --- --- 5 62,5 9 75 6 33,3 13 41,9 --- --- 33 47,8 

37 --- --- --- --- --- --- 2 18,2 4 19 --- --- 6 15,4 

38 --- --- 3 60 3 37,5 4 40 6 33,3 --- --- 16 38,1 

39 --- --- 2 40 6 33,3 3 25 4 18,2 1 50 16 27,1 

40 --- --- 2 50 1 20 4 50 7 53,8 --- --- 14 45,2 

41 --- --- 1 9,1 3 25 4 26,7 4 19 --- --- 12 20 

42 --- --- 1 50 3 50 4 22,2 1 12,5 --- --- 9 26,5 

43 --- --- 1 50 6 66,7 4 36,4 18 60 --- --- 29 55,8 

44 --- --- --- --- 5 55,6 6 50 15 60 --- --- 26 50 

45 --- --- --- --- 2 28,6 3 25 4 25 --- --- 9 22,5 

TOTAL 

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Unit 

Code 

Multiple Gestation Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 1251 - 1500 gr. > 1500 gr. TOTAL 

N % N % N % N % N % N % N % 

46 --- --- 1 50 --- --- 2 40 3 100 --- --- 6 54,5 

47 --- --- --- --- 1 25 2 33,3 3 20 --- --- 6 21,4 

48 --- --- --- --- --- --- 1 25 10 52,6 --- --- 11 37,9 

49 --- --- 1 33,3 4 80 1 10 2 50 --- --- 8 36,4 

50 --- --- 1 25 7 87,5 3 42,9 4 50 --- --- 15 55,6 

51 --- --- 4 36,4 6 26,1 7 20 9 32,1 6 27,3 32 26,4 

52 1 33,3 6 31,6 10 23,8 9 24,3 20 40,8 --- --- 46 30,7 

53 --- --- 3 50 --- --- 3 60 4 30,8 --- --- 10 33,3 

54 --- --- --- --- --- --- 2 100 4 57,1 --- --- 6 46,2 

55 --- --- --- --- 15 41,7 22 36,7 35 50,7 --- --- 72 38,9 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- 1 12,5 1 9,1 3 25 6 26,1 --- --- 11 20,4 

58 --- --- 2 50 2 15,4 4 22,2 8 30,8 --- --- 16 26,2 

59 --- --- --- --- --- --- 1 33,3 2 28,6 --- --- 3 21,4 

60 --- --- --- --- 2 28,6 3 23,1 2 12,5 --- --- 7 17,5 

61 --- --- 3 33,3 5 55,6 5 35,7 6 46,2 --- --- 19 42,2 

62 --- --- 5 71,4 1 16,7 1 11,1 3 30 --- --- 10 30,3 

63 --- --- 3 37,5 2 8,3 17 42,5 15 30,6 --- --- 37 30,6 

64 --- --- --- --- 2 40 1 8,3 7 30,4 --- --- 10 24,4 

65 --- --- --- --- --- --- 3 30 3 21,4 --- --- 6 15,8 

66 --- --- 1 20 8 32 7 33,3 8 47,1 --- --- 24 34,8 

67 --- --- 7 38,9 12 40 8 25 21 47,7 1 100 49 39,2 

68 --- --- 2 18,2 6 50 2 11,1 3 20 --- --- 13 23,2 

69 --- --- 1 33,3 --- --- 3 50 3 25 --- --- 7 31,8 

70 --- --- 1 16,7 11 44 10 50 19 50 19 70,4 60 51,7 

71 --- --- 5 62,5 4 66,7 2 33,3 9 75 --- --- 20 62,5 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- --- --- 2 40 4 30,8 --- --- --- --- 6 24 

74 1 50 7 41,2 9 37,5 7 30,4 7 26,9 14 48,3 45 37,2 

75 --- --- 7 58,3 4 33,3 13 46,4 8 29,6 8 40 40 40 

76 --- --- 8 38,1 12 42,9 7 23,3 14 42,4 7 23,3 48 32,9 

77 1 33,3 7 77,8 --- --- 5 38,5 12 50 3 37,5 28 41,2 

78 --- --- --- --- --- --- 7 50 7 53,8 3 30 17 35,4 

79 --- --- --- --- --- --- 4 23,5 8 30,8 5 27,8 17 21 

80 --- --- 1 33,3 7 63,6 2 33,3 10 62,5 1 33,3 21 53,8 

81 --- --- 5 50 5 23,8 3 13,6 16 38,1 9 39,1 38 31,7 

82 --- --- 1 20 4 36,4 3 25 5 26,3 4 26,7 17 27 

83 5 71,4 7 28 9 31 12 37,5 17 39,5 22 57,9 72 41,4 

84 --- --- 1 11,1 7 38,9 3 18,8 19 45,2 --- --- 30 34,1 

85 --- --- --- --- 4 50 --- --- 2 15,4 --- --- 6 17,6 

86 --- --- 3 60 7 38,9 1 16,7 7 46,7 4 66,7 22 44 

87 2 100 1 33,3 --- --- 7 35 7 30,4 7 43,8 24 35,3 

88 --- --- 8 29,6 9 34,6 10 28,6 13 33,3 5 19,2 45 29 

89 --- --- --- --- --- --- 5 38,5 7 58,3 5 31,3 17 37 

90 --- --- --- --- 3 33,3 4 36,4 8 32 8 36,4 23 32,4 

91 --- --- --- --- --- --- 3 33,3 5 31,3 3 25 11 23,4 

92 1 100 9 25,7 19 45,2 22 43,1 24 40,7 1 50 76 40 

93 4 28,6 6 15,8 8 22,9 8 17 19 31,7 13 25,5 58 23,7 

94 1 9,1 6 23,1 15 38,5 13 43,3 10 40 3 20 48 32,9 

95 1 100 --- --- 4 33,3 2 28,6 5 29,4 6 54,5 18 31 

96 --- --- --- --- 6 35,3 4 30,8 5 22,7 2 12,5 17 24,3 

TOTAL 27 25 235 27,1 443 31,6 551 32,2 886 36,8 316 33,6 2458 33,1 



EuroNeoNet 


6.1.2 Multiple Gestation Rate by Gestational Age per Unit. 

Table 6.1.2 shows the multiple gestation distribution according to gestational 

age for each Unit. 

Unit 

Code 

Multiple Gestation Rate against Gestational Age by Participating Unit 

< 24 wk. 24 - 25 wk. 26 - 27 wk. 28 - 29 wk. 30 - 31 wk. > 31 wk. TOTAL 

N % N % N % N % N % N % N % 

1 1 50 3 30 8 47,1 6 27,3 11 33,3 7 63,6 36 37,9 

2 --- --- --- --- --- --- --- --- 3 21,4 3 60 6 24 

3 --- --- 2 14,3 8 42,1 9 27,3 19 27,1 3 21,4 41 26,5 

4 2 66,7 2 25 --- --- 1 7,1 10 37 4 57,1 19 27,1 

5 2 22,2 --- --- 11 27,5 12 42,9 17 25 3 27,3 45 26,9 

6 3 37,5 5 26,3 9 31 14 35,9 22 35,5 5 33,3 58 33,7 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- 6 46,2 --- --- 6 27,3 

9 --- --- --- --- 2 33,3 --- --- 4 30,8 --- --- 6 16,7 

10 --- --- 4 57,1 2 50 2 14,3 13 46,4 3 42,9 24 39,3 

11 --- --- 4 30,8 11 57,9 6 16,2 12 23,1 11 45,8 44 30,3 

12 --- --- 9 24,3 17 25,4 35 30,2 69 39,2 32 38,1 162 33,7 

13 --- --- --- --- --- --- 3 42,9 --- --- 1 16,7 4 16 

14 --- --- --- --- 12 34,3 27 33,3 51 40,5 21 32,3 111 34,3 

15 --- --- 1 25 --- --- 1 5,9 9 36 5 22,7 16 19,3 

16 --- --- --- --- 2 50 2 50 4 22,2 7 58,3 15 37,5 

17 --- --- 2 66,7 3 18,8 9 39,1 13 41,9 7 41,2 34 37,8 

18 --- --- --- --- 2 18,2 10 62,5 4 15,4 5 41,7 21 30,4 

19 --- --- 1 12,5 --- --- 2 12,5 11 39,3 2 18,2 16 23,9 

20 --- --- 2 25 4 23,5 2 20 14 45,2 3 23,1 25 31,6 

21 --- --- 2 66,7 2 40 2 33,3 7 33,3 2 33,3 15 36,6 

22 --- --- 4 57,1 2 22,2 6 40 4 17,4 3 30 19 29,7 

23 1 100 9 31 11 27,5 15 24,2 17 25,8 1 5,9 54 25,1 

24 --- --- 2 13,3 17 34,7 24 40,7 19 39,6 --- --- 62 36 

25 --- --- --- --- --- --- 2 16,7 1 25 4 57,1 7 28 

26 1 50 4 40 5 33,3 6 42,9 14 73,7 5 55,6 35 50,7 

27 --- --- --- --- 2 16,7 10 50 4 50 --- --- 16 33,3 

28 --- --- --- --- 4 80 2 50 3 50 4 100 13 68,4 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 6 50 5 31,3 2 20 10 55,6 6 37,5 29 39,2 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- 4 57,1 1 14,3 2 28,6 --- --- 3 60 10 31,3 

33 --- --- 5 29,4 14 50 11 45,8 27 54 10 50 67 47,9 

34 --- --- 2 33,3 2 16,7 4 50 5 71,4 3 33,3 16 38,1 

35 --- --- 2 66,7 3 42,9 --- --- 2 33,3 --- --- 7 28 

36 --- --- 6 75 4 50 9 56,3 8 42,1 6 33,3 33 47,8 

37 --- --- --- --- --- --- --- --- 4 26,7 2 20 6 15,4 

38 --- --- 3 100 2 28,6 2 18,2 6 54,5 3 30 16 38,1 

39 --- --- --- --- 7 46,7 6 37,5 1 10 2 14,3 16 27,1 

40 1 100 --- --- 1 33,3 3 30 6 60 3 42,9 14 45,2 

41 --- --- --- --- 4 44,4 2 11,8 4 33,3 2 13,3 12 20 

42 --- --- --- --- 5 55,6 1 12,5 2 22,2 1 16,7 9 26,5 

43 --- --- 2 33,3 --- --- 3 50 11 64,7 13 65 29 55,8 

44 --- --- 2 50 2 25 3 25 4 44,4 15 78,9 26 50 

45 --- --- --- --- --- --- 5 29,4 1 14,3 3 30 9 22,5 



EuroNeoNet 


Unit 

Code 

Multiple Gestation Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 1 100 --- --- --- --- 2 40 2 66,7 1 100 6 54,5 

47 --- --- --- --- 2 40 1 14,3 2 25 1 16,7 6 21,4 

48 --- --- --- --- --- --- 4 40 5 71,4 2 28,6 11 37,9 

49 --- --- 1 100 2 25 2 33,3 3 42,9 --- --- 8 36,4 

50 --- --- 2 50 4 66,7 4 57,1 3 42,9 2 66,7 15 55,6 

51 2 50 3 20 7 38,9 --- --- 12 30,8 8 47,1 32 26,4 

52 2 100 5 18,5 4 16,7 9 28,1 17 44,7 9 33,3 46 30,7 

53 --- --- 2 66,7 2 25 --- --- 6 66,7 --- --- 10 33,3 

54 --- --- --- --- --- --- --- --- 4 80 2 50 6 46,2 

55 --- --- --- --- 19 37,3 19 43,2 17 40,5 17 53,1 72 38,9 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- 1 20 --- --- 2 15,4 5 50 3 21,4 11 20,4 

58 --- --- 2 40 2 25 3 27,3 5 25 4 25 16 26,2 

59 --- --- --- --- --- --- --- --- 1 25 2 40 3 21,4 

60 --- --- --- --- 3 60 1 12,5 3 20 --- --- 7 17,5 

61 --- --- 1 20 4 50 2 22,2 8 50 4 57,1 19 42,2 

62 --- --- 3 60 4 44,4 --- --- 1 12,5 2 28,6 10 30,3 

63 --- --- 2 28,6 2 8,3 12 48 11 31,4 10 33,3 37 30,6 

64 --- --- --- --- 1 14,3 2 22,2 3 25 4 33,3 10 24,4 

65 --- --- --- --- --- --- 4 33,3 2 50 --- --- 6 15,8 

66 1 50 2 18,2 --- --- 13 52 5 38,5 3 42,9 24 34,8 

67 --- --- 8 44,4 8 34,8 16 40 12 44,4 5 29,4 49 39,2 

68 --- --- --- --- 7 41,2 2 14,3 3 21,4 1 20 13 23,2 

69 --- --- --- --- 1 25 1 33,3 2 50 3 30 7 31,8 

70 --- --- 6 50 6 35,3 6 26,1 31 70,5 11 55 60 51,7 

71 --- --- 5 71,4 2 33,3 3 75 6 75 4 57,1 20 62,5 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- --- --- 2 33,3 2 25 2 28,6 --- --- 6 24 

74 --- --- 5 38,5 11 45,8 12 34,3 17 34,7 --- --- 45 37,2 

75 --- --- 8 66,7 2 15,4 8 36,4 17 44,7 5 33,3 40 40 

76 --- --- 7 36,8 9 37,5 5 19,2 19 33,9 8 38,1 48 32,9 

77 --- --- 6 54,5 3 33,3 6 30 11 55 2 25 28 41,2 

78 --- --- --- --- --- --- 6 37,5 8 42,1 3 60 17 35,4 

79 --- --- --- --- --- --- 6 30 8 26,7 3 25 17 21 

80 --- --- --- --- 6 60 4 57,1 4 44,4 7 58,3 21 53,8 

81 --- --- 5 62,5 3 16,7 6 20 16 35,6 8 42,1 38 31,7 

82 --- --- --- --- 4 36,4 5 33,3 8 30,8 --- --- 17 27 

83 6 66,7 --- --- 13 38,2 15 35,7 36 54,5 2 18,2 72 41,4 

84 --- --- 4 36,4 4 26,7 2 15,4 16 45,7 4 33,3 30 34,1 

85 --- --- 2 33,3 2 40 --- --- 2 16,7 --- --- 6 17,6 

86 --- --- 3 42,9 4 36,4 4 44,4 10 58,8 1 20 22 44 

87 3 100 --- --- --- --- 2 16,7 16 48,5 3 33,3 24 35,3 

88 1 25 9 39,1 7 23,3 8 25,8 15 32,6 5 23,8 45 29 

89 --- --- --- --- --- --- 4 40 11 47,8 2 25 17 37 

90 --- --- 2 40 2 18,2 2 15,4 16 43,2 1 20 23 32,4 

91 --- --- --- --- --- --- 2 14,3 6 33,3 3 60 11 23,4 

92 1 20 12 36,4 15 34,1 20 41,7 18 48,6 10 43,5 76 40 

93 4 19 6 23,1 5 16,1 12 25 21 24,1 10 31,3 58 23,7 

94 --- --- 7 21,9 11 34,4 20 57,1 7 22,6 3 27,3 48 32,9 

95 1 25 1 11,1 1 50 4 30,8 9 47,4 2 18,2 18 31 

96 --- --- --- --- 5 38,5 6 35,3 5 16,1 1 14,3 17 24,3 

TOTAL 33 28,4 208 28,2 373 29,6 531 30,7 919 37,5 394 34,6 2458 33,1 



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6.1.3 Multiple Gestation Standardized Rate by Perintal Risk Factors. 

Graph 6.1.3, corresponds to the 95% CI for the standardised multiple 

gestation adjusted rate. 

The general interpretation for graphs like 6.1.3 is the following: 

 

 

 

If the standardised rate is under 1, the male rate in the Unit studied is below the 

one expected in the standard population. Moreover, if the complete CI for the 

standardised rate is under 1, this rate will be below the standard population rate 

with a 95% confidence, for any sample of the studied Unit. 

If number 1 is inside the 95% CI, sometimes the rate will be below the standard 

population rate or above it. 

On the other hand, when the 95% CI is completely above number one, the rate 

for the Unit studied will be above the standard population rate in any sample 

you choose for that Unit with a 95% confidence. 



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Graph 6.1.3 

The explanation for Unit 19 is the following: 

 

The standardised multiple gestation rate is under 1, so the multiple gestation rate in the studied Unit is lower than the rate in the 

standard population. However, number one is inside the 95% CI, so with a 95% confidence level the standardised multiple gestation rate 

will sometimes be under and above one. Therefore there is no statistical significant evidence that the multiple gestation rate for Unit 19 

is different to the standard's population rate. 

The results for Units 9, 13, 15, 23, 37, 41, 60, 65, 79, 85 and 93 reached statistical significant relevance, being the multiple 

gestation rate for these Units significantly smaller than the one expected according to the standard’s population multiple 

gestation distribution. On the other hand, Units 26, 33, 43, 70 and 71 had a bigger significant multiple gestation rate than 

the one expected according to the standard’s population multiple gestation distribution. 

Units 29, 31 and 56 didn’t register multiple gestations. 

Note 1: Standardization items: Birth weight Z-Score by gestational age and gender. 

Note 2: Units with 5 or less babies admitted have not been analyzed in this section. 



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6.2 Prenatal Steroids Rate. 

Definition: Betamethasone, dexamethasone or hydrocortisone given prior to delivery 

(Incomplete and Complete administration). 

6.2.1 Prenatal Steroids Rate by Birth Weight. 

The global prenatal steroids (Inc. + Compl.) rate for 2010 cohort has been of 

84.5%, with a variation of 13.8% and 100% within units. 

Unit 

Code 

Prenatal Steroids Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 1 100 8 100 13 86,7 17 81 22 71 19 100 80 84,2 

2 --- --- 1 100 3 100 3 60 5 71,4 9 100 21 84 

3 1 100 11 68,8 19 82,6 26 70,3 30 83,3 34 81 121 78,1 

4 3 100 5 62,5 7 87,5 14 87,5 17 81 11 78,6 57 81,4 

5 2 66,7 16 76,2 27 90 28 87,5 28 71,8 28 66,7 129 77,2 

6 6 66,7 15 93,8 31 91,2 26 96,3 29 65,9 36 85,7 143 83,1 

7 --- --- --- --- --- --- --- --- --- --- 1 100 1 33,3 

8 --- --- --- --- 2 100 6 100 4 57,1 3 60 15 75 

9 --- --- --- --- 2 66,7 6 60 12 80 6 85,7 26 72,2 

10 1 100 7 100 7 100 12 75 12 85,7 13 81,3 52 85,2 

11 1 100 12 92,3 25 100 29 87,9 39 83 24 92,3 130 89,7 

12 3 100 52 92,9 72 88,9 87 87,9 136 88,3 75 86,2 425 88,5 

13 --- --- 1 100 4 80 1 50 12 100 5 100 23 92 

14 3 100 30 90,9 42 89,4 60 89,6 104 84,6 47 92,2 286 88,3 

15 1 100 5 83,3 21 95,5 6 85,7 35 97,2 10 90,9 78 94 

16 --- --- 1 50 3 75 3 75 16 84,2 7 63,6 30 75 

17 --- --- 8 88,9 14 100 23 88,5 25 89,3 12 92,3 82 91,1 

18 --- --- 2 50 6 85,7 16 69,6 19 86,4 9 69,2 52 75,4 

19 1 100 7 87,5 4 66,7 12 80 17 89,5 18 100 59 88,1 

20 1 100 5 100 14 77,8 14 87,5 15 62,5 12 80 61 77,2 

21 --- --- 2 66,7 2 40 9 81,8 15 83,3 2 50 30 73,2 

22 1 100 5 100 11 100 11 91,7 15 78,9 12 75 55 85,9 

23 1 100 30 96,8 43 84,3 50 87,7 47 97,9 22 81,5 193 89,8 

24 --- --- 24 92,3 49 86 42 85,7 37 90,2 --- --- 152 87,9 

25 --- --- --- --- 3 100 9 90 9 75 --- --- 21 84 

26 --- --- 16 84,2 11 78,6 14 100 19 90,5 --- --- 60 88,2 

27 --- --- 5 83,3 11 91,7 8 88,9 14 66,7 --- --- 38 79,2 

28 --- --- --- --- 8 100 2 100 9 100 --- --- 19 100 

29 1 100 1 100 1 33,3 2 66,7 7 77,8 --- --- 12 70,6 

30 --- --- 8 80 16 88,9 9 90 26 92,9 --- --- 59 89,4 

31 --- --- --- --- 3 100 1 50 5 100 --- --- 9 90 

32 1 50 5 83,3 7 100 8 100 7 77,8 --- --- 28 87,5 

33 3 75 15 83,3 26 83,9 31 91,2 47 90,4 1 100 123 87,9 

34 1 100 5 83,3 9 100 9 90 11 100 --- --- 35 94,6 

35 1 100 6 100 8 100 3 100 7 100 --- --- 25 100 

36 --- --- 7 87,5 9 75 11 61,1 19 61,3 --- --- 46 66,7 

37 --- --- 3 100 3 100 11 100 17 81 --- --- 34 87,2 

38 1 100 5 100 7 87,5 9 90 10 58,8 --- --- 32 78 

39 --- --- 5 100 13 72,2 11 91,7 16 72,7 2 100 47 79,7 

40 --- --- 2 66,7 1 100 5 62,5 11 91,7 1 100 20 80 

41 --- --- 8 72,7 10 83,3 15 100 14 70 1 100 48 81,4 

42 --- --- 2 100 5 83,3 14 77,8 4 50 --- --- 25 73,5 

43 --- --- 1 50 9 100 10 90,9 23 76,7 --- --- 43 82,7 

44 --- --- 6 100 8 88,9 11 100 19 76 --- --- 44 86,3 

45 --- --- 4 80 7 100 11 91,7 12 75 --- --- 34 85 



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Unit 

Code 

Prenatal Steroids Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

46 1 100 2 100 --- --- 4 80 2 100 --- --- 9 90 

47 --- --- 2 66,7 3 75 5 83,3 9 60 --- --- 19 67,9 

48 --- --- 1 100 4 80 3 75 17 89,5 --- --- 25 86,2 

49 --- --- 3 100 5 100 10 100 4 100 --- --- 22 100 

50 --- --- 3 75 8 100 6 100 7 87,5 --- --- 24 92,3 

51 2 100 10 90,9 21 91,3 30 85,7 26 92,9 22 100 111 91,7 

52 2 100 18 100 35 87,5 32 86,5 35 71,4 --- --- 122 83,6 

53 --- --- 6 100 6 100 2 66,7 11 84,6 --- --- 25 89,3 

54 1 100 3 100 --- --- 1 50 5 71,4 --- --- 10 76,9 

55 --- --- 18 90 31 86,1 47 87 62 89,9 --- --- 158 88,3 

56 --- --- --- --- 4 100 6 100 6 85,7 --- --- 16 94,1 

57 --- --- 7 87,5 11 100 12 100 18 78,3 --- --- 48 88,9 

58 --- --- 3 75 9 81,8 13 81,3 19 79,2 --- --- 44 80 

59 --- --- 2 100 2 100 2 66,7 4 57,1 --- --- 10 71,4 

60 --- --- 3 75 6 85,7 10 76,9 12 75 --- --- 31 77,5 

61 --- --- 7 77,8 9 100 11 78,6 13 100 --- --- 40 88,9 

62 1 100 5 100 6 100 9 100 6 60 --- --- 27 87,1 

63 --- --- 7 87,5 19 86,4 35 89,7 36 81,8 --- --- 97 85,8 

64 --- --- 1 100 5 100 11 91,7 19 86,4 --- --- 36 90 

65 --- --- 4 66,7 7 87,5 9 90 12 85,7 --- --- 32 84,2 

66 1 100 4 80 22 91,7 21 100 15 88,2 --- --- 63 92,6 

67 --- --- 15 83,3 27 90 29 90,6 33 75 1 100 105 84 

68 --- --- 10 90,9 11 91,7 14 77,8 12 80 --- --- 47 83,9 

69 --- --- 3 100 1 100 6 100 10 83,3 --- --- 20 90,9 

70 --- --- 6 100 22 88 17 85 30 78,9 19 70,4 94 81 

71 --- --- 8 100 6 100 6 100 11 91,7 --- --- 31 96,9 

72 --- --- --- --- --- --- 1 100 1 100 --- --- 2 100 

73 1 100 3 100 5 100 9 69,2 2 66,7 --- --- 20 80 

74 2 100 17 100 16 66,7 18 78,3 24 92,3 20 69 97 80,2 

75 --- --- 9 75 9 75 24 85,7 20 74,1 19 95 81 81 

76 4 100 21 100 26 92,9 27 90 30 90,9 29 96,7 137 93,8 

77 3 100 9 100 10 90,9 10 76,9 19 79,2 6 75 57 83,8 

78 1 100 5 83,3 4 100 14 100 13 100 10 100 47 97,9 

79 1 100 10 90,9 8 100,0 17 100 23 88,5 13 72,2 72 88,9 

80 --- --- 3 100 9 81,8 5 83,3 14 87,5 2 66,7 33 84,6 

81 2 100 10 100 18 85,7 17 77,3 34 81 23 100 104 86,7 

82 1 100 5 100 10 90,9 11 91,7 14 73,7 15 100 56 88,9 

83 5 71,4 19 76 20 69 21 65,6 26 60,5 26 68,4 117 67,2 

84 3 100 5 55,6 16 88,9 15 93,8 32 76,2 --- --- 71 80,7 

85 1 100 4 100 4 50 3 60 5 38,5 1 33,3 18 52,9 

86 --- --- 4 80 16 88,9 6 100 13 86,7 5 83,3 44 88 

87 --- --- 2 66,7 4 100 20 100 22 95,7 16 100 64 94,1 

88 2 100 25 92,6 26 100 33 94,3 35 89,7 24 92,3 145 93,5 

89 --- --- 2 100 3 100 12 92,3 11 91,7 14 87,5 42 91,3 

90 --- --- 4 100 9 100 9 81,8 19 76 21 95,5 62 87,3 

91 --- --- 2 40 4 80 9 100 14 87,5 12 100 41 87,2 

92 1 100 29 85,3 35 83,3 44 86,3 49 87,5 2 100 160 86 

93 1 8,3 25 75,8 25 89,3 32 78 40 74,1 38 79,2 161 74,5 

94 11 100 24 100 36 94,7 27 93,1 21 87,5 13 86,7 132 93,6 

95 --- --- 1 10 1 8,3 2 28,6 1 5,9 3 27,3 8 13,8 

96 --- --- 2 100 16 94,1 11 84,6 20 90,9 14 87,5 63 90 

TOTAL 81 77,1 742 86,9 1206 87,3 1453 86,1 1933 81,4 788 84,1 6203 84,5 



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6.2.2 Prenatal Steroids Rate by Gestational Age. 

Table 6.2.2 shows the Prenatal Steroids distribution according to GA for each 

Unit. 

Unit 

Code 

Prenatal Steroids Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 2 100 9 90 15 88,2 20 90,9 29 87,9 5 45,5 80 84,2 

2 --- --- 2 100 --- --- 4 100 14 100 1 20 21 84 

3 4 80 13 92,9 13 68,4 24 72,7 57 81,4 10 71,4 121 78,1 

4 2 66,7 6 75 9 81,8 13 92,9 23 85,2 4 57,1 57 81,4 

5 7 77,8 9 81,8 34 85 24 85,7 48 70,6 7 63,6 129 77,2 

6 5 62,5 18 94,7 27 93,1 34 87,2 51 82,3 8 53,3 143 83,1 

7 --- --- --- --- --- --- --- --- 1 50 --- --- 1 33,3 

8 --- --- --- --- --- --- 2 100 10 76,9 3 60 15 75 

9 --- --- 2 100 3 50 7 77,8 11 84,6 3 60 26 72,2 

10 1 100 7 100 4 100 11 78,6 22 78,6 7 100 52 85,2 

11 --- --- 12 92,3 19 100 31 83,8 48 92,3 20 83,3 130 89,7 

12 1 100 31 83,8 58 86,6 106 91,4 158 89,8 71 85,5 425 88,5 

13 --- --- --- --- 1 50 7 100 9 100 6 100 23 92 

14 --- --- 12 75 33 94,3 75 92,6 116 92,1 50 76,9 286 88,3 

15 --- --- 2 50 15 100 17 100 24 96 20 90,9 78 94 

16 --- --- 1 100 4 100 4 100 13 72,2 8 66,7 30 75 

17 --- --- 3 100 15 93,8 21 91,3 28 90,3 15 88,2 82 91,1 

18 --- --- 2 50 7 63,6 15 93,8 18 69,2 10 83,3 52 75,4 

19 --- --- 5 62,5 4 100 14 87,5 27 96,4 9 81,8 59 88,1 

20 --- --- 6 75 15 88,2 9 90 23 74,2 8 61,5 61 77,2 

21 --- --- 3 100 1 20 4 66,7 17 81 5 83,3 30 73,2 

22 --- --- 6 85,7 9 100 15 100 19 82,6 6 60 55 85,9 

23 1 100 26 89,7 36 90 55 88,7 61 92,4 14 82,4 193 89,8 

24 --- --- 13 86,7 43 87,8 53 88,3 43 89,6 --- --- 152 87,9 

25 --- --- --- --- 1 50 12 100 3 75 5 71,4 21 84 

26 1 50 8 80 13 86,7 13 92,9 19 100 6 75 60 88,2 

27 --- --- 1 50 11 91,7 16 80 7 87,5 3 50 38 79,2 

28 --- --- --- --- 5 100 4 100 6 100 4 100 19 100 

29 --- --- 1 50 2 100 3 50 3 75 3 100 12 70,6 

30 2 100 11 91,7 9 69,2 9 100 17 100 11 84,6 59 89,4 

31 --- --- --- --- 1 100 2 100 2 66,7 4 100 9 90 

32 1 100 5 71,4 7 100 7 100 5 100 3 60 28 87,5 

33 --- --- 15 88,2 25 89,3 21 87,5 44 88 18 90 123 87,9 

34 --- --- 6 100 9 90 6 85,7 7 100 7 100 35 94,6 

35 --- --- 3 100 7 100 5 100 6 100 4 100 25 100 

36 --- --- 6 75 5 62,5 10 62,5 14 73,7 11 61,1 46 66,7 

37 --- --- 3 100 4 100 5 71,4 15 100 7 70 34 87,2 

38 --- --- 3 100 6 85,7 9 81,8 10 90,9 4 44,4 32 78 

39 1 50 1 50 12 80 15 93,8 10 100 8 57,1 47 79,7 

40 --- --- --- --- 2 100 6 75 6 85,7 6 85,7 20 80 

41 --- --- 5 71,4 6 66,7 15 88,2 11 91,7 11 78,6 48 81,4 

42 --- --- 2 100 7 77,8 7 87,5 8 88,9 1 16,7 25 73,5 

43 --- --- 5 83,3 2 66,7 6 100 15 88,2 15 75 43 82,7 

44 --- --- 4 100 7 87,5 11 91,7 8 88,9 14 77,8 44 86,3 

45 --- --- 2 66,7 3 100 17 100 5 71,4 7 70 34 85 



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Unit 

Code 

Prenatal Steroids Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 1 100 --- --- 1 100 4 80 3 100 --- --- 9 90 

47 --- --- 1 50 4 80 5 71,4 7 87,5 2 33,3 19 67,9 

48 --- --- --- --- 5 100 8 80 6 85,7 6 85,7 25 86,2 

49 --- --- 1 100 8 100 6 100 7 100 --- --- 22 100 

50 --- --- 3 75 6 100 7 100 5 83,3 3 100 24 92,3 

51 3 75 13 86,7 16 88,9 25 89,3 38 97,4 16 94,1 111 91,7 

52 2 100 23 92 21 91,3 30 93,8 32 86,5 14 51,9 122 83,6 

53 --- --- 3 100 6 100 4 80 7 77,8 5 100 25 89,3 

54 --- --- 3 100 1 100 --- --- 3 60 3 75 10 76,9 

55 2 100 13 92,9 38 77,6 40 95,2 39 97,5 26 81,3 158 88,3 

56 --- --- 3 100 2 100 5 100 3 100 3 75 16 94,1 

57 2 66,7 5 100 9 100 12 92,3 9 90 11 78,6 48 88,9 

58 --- --- 4 80 4 80 11 100 19 95 6 46,2 44 80 

59 --- --- 1 100 1 100 3 100 4 100 1 20 10 71,4 

60 --- --- 3 75 3 60 6 75 12 80 7 87,5 31 77,5 

61 --- --- 3 60 8 100 8 88,9 14 87,5 7 100 40 88,9 

62 --- --- 5 100 7 100 4 100 7 87,5 4 57,1 27 87,1 

63 --- --- 4 66,7 21 91,3 22 88 30 90,9 20 76,9 97 85,8 

64 --- --- 1 100 7 100 9 100 12 100 7 63,6 36 90 

65 --- --- 3 60 7 77,8 11 91,7 4 100 7 87,5 32 84,2 

66 2 100 8 80 10 90,9 25 100 13 100 5 71,4 63 92,6 

67 --- --- 15 83,3 21 91,3 35 87,5 22 81,5 12 70,6 105 84 

68 1 100 5 100 14 82,4 11 78,6 12 85,7 4 80 47 83,9 

69 1 100 --- --- 4 100 3 100 4 100 8 80 20 90,9 

70 --- --- 12 100 15 88,2 22 95,7 35 79,5 10 50 94 81 

71 --- --- 7 100 6 100 4 100 8 100 6 85,7 31 96,9 

72 --- --- --- --- --- --- 1 100 1 100 --- --- 2 100 

73 --- --- 2 100 5 83,3 6 75 5 71,4 2 100 20 80 

74 --- --- 12 92,3 20 83,3 25 71,4 40 81,6 --- --- 97 80,2 

75 --- --- 8 66,7 9 69,2 21 95,5 32 84,2 11 73,3 81 81 

76 --- --- 19 100 24 100 24 92,3 53 94,6 17 81 137 93,8 

77 --- --- 11 100 8 88,9 17 85 16 80 5 62,5 57 83,8 

78 --- --- 1 50 6 100 16 100 19 100 5 100 47 97,9 

79 --- --- 8 100 10 90,9 19 95 24 80 11 91,7 72 88,9 

80 --- --- 1 100 9 90 6 85,7 8 88,9 9 75 33 84,6 

81 --- --- 7 87,5 16 88,9 25 83,3 42 93,3 14 73,7 104 86,7 

82 --- --- 7 100 10 90,9 14 93,3 24 92,3 1 25 56 88,9 

83 4 44,4 9 75 25 73,5 28 66,7 46 69,7 5 45,5 117 67,2 

84 2 100 6 54,5 14 93,3 10 76,9 32 91,4 7 58,3 71 80,7 

85 1 100 5 83,3 2 40 3 37,5 7 58,3 --- --- 18 52,9 

86 1 100 5 71,4 10 90,9 9 100 15 88,2 4 80 44 88 

87 --- --- 1 100 10 100 12 100 33 100 8 88,9 64 94,1 

88 2 50 23 100 30 100 27 87,1 45 97,8 18 85,7 145 93,5 

89 --- --- 2 100 3 100 10 100 19 82,6 8 100 42 91,3 

90 --- --- 5 100 9 81,8 11 84,6 33 89,2 4 80 62 87,3 

91 --- --- 1 25 5 100 13 92,9 18 100 4 80 41 87,2 

92 5 100 27 84,4 35 81,4 43 89,6 30 85,7 20 87 160 86 

93 4 23,5 20 87 22 84,6 34 85 65 78,3 16 59,3 161 74,5 

94 5 100 31 100 29 96,7 33 97,1 25 83,3 9 81,8 132 93,6 

95 1 25 --- --- --- --- 3 23,1 4 21,1 --- --- 8 13,8 

96 --- --- 2 100 13 100 14 82,4 28 90,3 6 85,7 63 90 

TOTAL 67 59,8 621 85,2 1078 87,3 1508 87,8 2110 86,6 819 73,7 6203 84,5 



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6.2.3 Prenatal Steroids Standardized Rate by Perinatal Risk Factors. 

Graph 6.2.3 

The results for Units 83, 85, 93 and 95 reached statistical significant relevance, being the multiple gestation rate for these 

Units significantly smaller than the one expected according to the standard’s population multiple gestation distribution. 





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6.3 Caesarean section Rate. 

Definition: any caesarean delivery (elective or emergency). 

6.3.1 Caesarean Section Rate by Birth Weight. 

The global Caesarean Section rate for 2010 cohort has been of 70.8%, with a 

variation of 46.6% and 100% within units. 

Unit 

Code 

Caesarean Section Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- 4 50 10 66,7 18 85,7 19 61,3 9 47,4 60 63,2 

2 --- --- 1 100 2 66,7 5 100 6 85,7 2 22,2 16 64 

3 1 100 10 62,5 19 82,6 31 83,8 30 83,3 20 47,6 111 71,6 

4 1 33,3 5 62,5 7 87,5 9 56,3 17 81 9 64,3 48 68,6 

5 3 100 16 76,2 25 83,3 22 68,8 29 74,4 25 59,5 120 71,9 

6 5 55,6 9 56,3 25 73,5 14 51,9 23 52,3 23 54,8 99 57,6 

7 --- --- --- --- --- --- --- --- 2 100 1 100 3 100 

8 --- --- --- --- 2 100 6 100 9 100 1 20 18 81,8 

9 --- --- --- --- 1 33,3 7 70 12 80 2 28,6 22 61,1 

10 1 100 5 71,4 6 85,7 12 75 9 64,3 14 87,5 47 77 

11 1 100 7 53,8 19 76 23 69,7 35 74,5 17 65,4 102 70,3 

12 1 33,3 36 64,3 62 76,5 82 82,8 107 69 52 59,8 340 70,7 

13 --- --- 1 100 5 100 --- --- 11 91,7 1 20 18 72 

14 3 100 23 69,7 35 74,5 56 83,6 100 81,3 29 56,9 246 75,9 

15 1 100 5 83,3 18 81,8 3 42,9 30 83,3 --- --- 57 68,7 

16 --- --- 1 50 3 75 3 75 15 78,9 6 54,5 28 70 

17 --- --- 9 100 13 92,9 24 92,3 23 82,1 12 92,3 81 90 

18 --- --- 3 75 3 42,9 13 56,5 15 68,2 6 46,2 40 58 

19 1 100 5 62,5 4 66,7 14 93,3 14 73,7 11 61,1 49 73,1 

20 --- --- 5 100 12 66,7 14 87,5 19 79,2 13 86,7 63 79,7 

21 --- --- 1 33,3 1 20 9 81,8 13 72,2 1 25 25 61 

22 1 100 2 40 7 63,6 7 58,3 10 52,6 5 31,3 32 50 

23 1 100 13 41,9 39 78 37 64,9 34 70,8 19 70,4 143 66,8 

24 --- --- 20 80 43 79,6 40 85,1 30 75 --- --- 133 80,1 

25 --- --- --- --- 2 66,7 3 30 7 58,3 --- --- 12 48 

26 --- --- 13 68,4 8 57,1 11 78,6 14 63,6 --- --- 46 66,7 

27 --- --- 3 50 9 75 8 88,9 19 90,5 --- --- 39 81,3 

28 --- --- --- --- 6 75 --- --- 7 77,8 --- --- 13 68,4 

29 1 100 1 100 2 66,7 3 100 8 88,9 --- --- 15 88,2 

30 --- --- 5 50 10 50 10 90,9 21 63,6 --- --- 46 62,2 

31 --- --- --- --- 2 66,7 2 100 5 83,3 --- --- 9 81,8 

32 1 50 2 33,3 4 57,1 3 37,5 5 55,6 --- --- 15 46,9 

33 3 75 5 27,8 21 67,7 23 67,6 35 67,3 1 100 88 62,9 

34 1 100 4 66,7 4 33,3 8 80 9 69,2 --- --- 26 61,9 

35 1 100 3 50 4 50 3 100 4 57,1 --- --- 15 60 

36 --- --- 5 62,5 7 58,3 13 72,2 29 93,5 --- --- 54 78,3 

37 --- --- 3 100 3 100 8 72,7 17 81 --- --- 31 79,5 

38 1 100 5 100 6 75 10 100 17 94,4 --- --- 39 92,9 

39 --- --- 4 80 15 83,3 9 75 15 68,2 2 100 45 76,3 

40 --- --- 2 50 5 100 8 100 12 92,3 1 100 28 90,3 

41 --- --- 8 72,7 10 83,3 13 86,7 17 81 1 100 49 81,7 

42 --- --- 2 100 6 100 13 72,2 8 100 --- --- 29 85,3 

43 --- --- 1 50 6 66,7 8 72,7 25 83,3 --- --- 40 76,9 

44 --- --- 5 83,3 7 77,8 7 58,3 15 60 --- --- 34 65,4 



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Unit 

Code 

Caesarean Section Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

45 --- --- 4 80 6 85,7 10 83,3 10 62,5 --- --- 30 75 

46 1 100 1 50 --- --- 5 100 3 100 --- --- 10 90,9 

47 --- --- 1 33,3 3 75 4 66,7 10 66,7 --- --- 18 64,3 

48 --- --- 1 100 4 80 3 75 14 73,7 --- --- 22 75,9 

49 --- --- 1 33,3 5 100 7 70 3 75 --- --- 16 72,7 

50 --- --- 3 75 7 87,5 6 85,7 7 87,5 --- --- 23 85,2 

51 2 100 7 63,6 20 87 22 62,9 20 71,4 14 63,6 85 70,2 

52 2 66,7 13 68,4 31 73,8 31 83,8 36 73,5 --- --- 113 75,3 

53 --- --- 6 100 3 50 5 100 9 69,2 --- --- 23 76,7 

54 1 100 1 33,3 --- --- 2 100 7 100 --- --- 11 84,6 

55 --- --- 14 70 30 83,3 52 86,7 54 78,3 --- --- 150 81,1 

56 --- --- --- --- --- --- 1 16,7 7 100 --- --- 8 47,1 

57 --- --- 2 25 8 72,7 11 91,7 13 56,5 --- --- 34 63 

58 --- --- 1 25 9 69,2 11 61,1 16 61,5 --- --- 37 60,7 

59 --- --- 2 100 2 100 2 66,7 5 71,4 --- --- 11 78,6 

60 --- --- 3 75 5 71,4 10 76,9 11 68,8 --- --- 29 72,5 

61 --- --- 7 77,8 9 100 13 92,9 12 92,3 --- --- 41 91,1 

62 1 100 2 28,6 6 100 5 55,6 7 70 --- --- 21 63,6 

63 --- --- 3 37,5 11 45,8 32 80 36 73,5 --- --- 82 67,8 

64 --- --- 1 100 3 60 9 75 17 73,9 --- --- 30 73,2 

65 --- --- 3 50 1 12,5 7 70 10 71,4 --- --- 21 55,3 

66 1 100 3 60 14 56 17 81 10 58,8 --- --- 45 65,2 

67 --- --- 13 72,2 18 60 21 65,6 26 59,1 1 100 79 63,2 

68 --- --- 10 90,9 11 91,7 8 44,4 11 73,3 --- --- 40 71,4 

69 --- --- 1 33,3 1 100 5 83,3 11 91,7 --- --- 18 81,8 

70 --- --- 1 16,7 20 80 12 60 26 68,4 17 63 76 65,5 

71 --- --- 6 75 3 50 4 66,7 8 66,7 --- --- 21 65,6 

72 --- --- --- --- --- --- --- --- 1 100 --- --- 1 50 

73 --- --- 2 66,7 5 100 8 61,5 2 66,7 --- --- 17 68 

74 2 100 14 82,4 20 83,3 17 73,9 11 42,3 20 69 84 69,4 

75 1 100 4 33,3 11 91,7 17 60,7 15 55,6 14 70 62 62 

76 3 75 16 76,2 23 82,1 26 86,7 29 87,9 19 63,3 116 79,5 

77 3 100 9 100 11 100 12 92,3 23 95,8 7 87,5 65 95,6 

78 1 100 5 83,3 3 75 12 85,7 10 76,9 7 70 38 79,2 

79 1 100 10 90,9 7 87,5 17 100 19 73,1 13 72,2 67 82,7 

80 --- --- 3 100 11 100 6 100 15 93,8 2 66,7 37 94,9 

81 1 50 6 60 11 52,4 16 72,7 30 71,4 17 73,9 81 67,5 

82 1 100 5 100 11 100 12 100 17 89,5 12 80 58 92,1 

83 5 71,4 17 68 23 79,3 30 93,8 40 93 33 86,8 148 85,1 

84 3 100 8 88,9 17 94,4 14 87,5 39 92,9 --- --- 81 92 

85 1 100 4 100 8 100 5 100 12 92,3 2 66,7 32 94,1 

86 --- --- 4 80 14 77,8 6 100 12 80 5 83,3 41 82 

87 --- --- 1 33,3 2 50 16 80 15 65,2 6 37,5 40 58,8 

88 1 50 19 70,4 15 57,7 29 82,9 32 82,1 20 76,9 116 74,8 

89 --- --- 2 100 3 100 12 92,3 6 50 9 56,3 32 69,6 

90 --- --- 4 100 6 66,7 7 63,6 20 80 12 54,5 49 69 

91 --- --- 2 40 1 20 7 77,8 9 56,3 3 25 22 46,8 

92 --- --- 11 31,4 30 71,4 32 62,7 29 49,2 1 50 103 54,2 

93 --- --- 17 44,7 20 58,8 26 55,3 40 66,7 31 60,8 134 54,9 

94 7 63,6 11 42,3 14 35,9 15 50 13 52 8 53,3 68 46,6 

95 --- --- 2 20 8 66,7 6 85,7 17 100 11 100 44 75,9 

96 --- --- 2 100 15 88,2 11 84,6 19 86,4 6 37,5 53 75,7 

TOTAL 66 61,1 540 62,4 1017 72,6 1286 75,3 1775 73,7 573 61 5257 70,8 



EuroNeoNet 


6.3.2 Caesarean Section Rate by Gestational Age 

Table 6.3.2 shows the Caesarean Section distribution according to Gestational 

Age for each Unit. 

Caesarean Section Rate against Gestational Age by Participating Unit 

Unit 

Code 


1 --- --- 4 40 13 76,5 15 68,2 18 54,5 10 90,9 60 63,2 

2 --- --- 1 50 --- --- 2 50 8 57,1 5 100 16 64 

3 2 40 7 50 18 94,7 25 75,8 46 65,7 13 92,9 111 71,6 

4 1 33,3 5 62,5 8 72,7 6 42,9 21 77,8 7 100 48 68,6 

5 4 44,4 10 90,9 29 72,5 20 71,4 46 67,6 11 100 120 71,9 

6 1 12,5 12 63,2 20 69 21 53,8 36 58,1 9 60 99 57,6 

7 --- --- --- --- --- --- --- --- 2 100 1 100 3 100 

8 --- --- --- --- --- --- 2 100 9 69,2 7 100 18 81,8 

9 --- --- 1 50 3 50 4 44,4 9 69,2 5 100 22 61,1 

10 --- --- 6 85,7 3 75 9 64,3 22 78,6 7 100 47 77 

11 --- --- 2 15,4 15 78,9 24 64,9 38 73,1 23 95,8 102 70,3 

12 --- --- 16 43,2 46 68,7 88 75,9 121 68,8 69 82,1 340 70,7 

13 --- --- 1 100 1 50 6 85,7 4 44,4 6 100 18 72 

14 --- --- 4 25 29 82,9 62 76,5 90 71,4 61 93,8 246 75,9 

15 --- --- 1 25 12 80 12 70,6 11 44 21 95,5 57 68,7 

16 1 100 --- --- 3 75 3 75 10 55,6 11 91,7 28 70 

17 --- --- 3 100 14 87,5 23 100 25 80,6 16 94,1 81 90 

18 --- --- --- --- 7 63,6 10 62,5 15 57,7 8 66,7 40 58 

19 --- --- 3 37,5 4 100 11 68,8 21 75 10 90,9 49 73,1 

20 --- --- 3 37,5 15 88,2 10 100 23 74,2 12 92,3 63 79,7 

21 --- --- --- --- 2 40 3 50 14 66,7 6 100 25 61 

22 --- --- 3 42,9 5 55,6 10 66,7 7 30,4 7 70 32 50 

23 --- --- 10 35,7 26 65 42 67,7 50 75,8 15 88,2 143 66,8 

24 --- --- 9 60 36 80 48 84,2 40 83,3 --- --- 133 80,1 

25 --- --- --- --- 1 50 5 41,7 1 25 5 71,4 12 48 

26 --- --- 5 50 11 73,3 12 85,7 10 52,6 8 88,9 46 66,7 

27 --- --- 1 50 7 58,3 18 90 8 100 5 83,3 39 81,3 

28 --- --- --- --- 3 60 3 75 4 66,7 3 75 13 68,4 

29 --- --- 1 50 2 100 6 100 4 100 2 66,7 15 88,2 

30 --- --- 6 50 7 43,8 6 60 12 66,7 15 93,8 46 62,2 

31 --- --- --- --- --- --- 2 100 2 66,7 5 100 9 81,8 

32 --- --- 3 42,9 2 28,6 3 42,9 3 60 4 80 15 46,9 

33 --- --- 3 17,6 15 53,6 16 66,7 36 72 18 90 88 62,9 

34 --- --- 2 33,3 5 41,7 7 87,5 5 71,4 7 77,8 26 61,9 

35 --- --- --- --- 3 42,9 3 60 5 83,3 4 100 15 60 

36 --- --- 5 62,5 3 37,5 11 68,8 17 89,5 18 100 54 78,3 

37 --- --- 3 100 2 50 3 42,9 13 86,7 10 100 31 79,5 

38 --- --- 3 100 5 71,4 11 100 10 90,9 10 100 39 92,9 

39 --- --- 2 100 12 80 11 68,8 9 90 11 78,6 45 76,3 

40 --- --- --- --- 2 66,7 10 100 10 100 6 85,7 28 90,3 

41 --- --- 3 42,9 8 88,9 16 94,1 9 75 13 86,7 49 81,7 

42 --- --- 2 100 8 88,9 5 62,5 8 88,9 6 100 29 85,3 

43 --- --- 2 33,3 1 33,3 5 83,3 12 70,6 20 100 40 76,9 

44 --- --- 3 75 5 62,5 9 75 6 66,7 11 57,9 34 65,4 

45 --- --- 2 66,7 2 66,7 11 64,7 5 71,4 10 100 30 75 



EuroNeoNet 


Caesarean Section Rate against Gestational Age by Participating Unit 

Unit 

Code 


46 --- --- --- --- 1 100 5 100 3 100 1 100 10 90,9 

47 --- --- --- --- 4 80 3 42,9 5 62,5 6 100 18 64,3 

48 --- --- --- --- 4 80 7 70 5 71,4 6 85,7 22 75,9 

49 --- --- 1 100 5 62,5 5 83,3 5 71,4 --- --- 16 72,7 

50 --- --- 3 75 5 83,3 5 71,4 7 100 3 100 23 85,2 

51 3 75 9 60 13 72,2 18 64,3 26 66,7 16 94,1 85 70,2 

52 --- --- 17 63 18 75 25 78,1 31 81,6 22 81,5 113 75,3 

53 --- --- 3 100 5 62,5 4 80 7 77,8 4 80 23 76,7 

54 --- --- 1 33,3 1 100 --- --- 5 100 4 100 11 84,6 

55 --- --- 7 50 40 78,4 39 88,6 34 81 30 93,8 150 81,1 

56 --- --- --- --- --- --- 1 20 3 100 4 100 8 47,1 

57 --- --- --- --- 8 88,9 12 92,3 3 30 11 78,6 34 63 

58 --- --- 1 20 4 50 7 63,6 11 55 14 87,5 37 60,7 

59 --- --- 1 100 1 100 2 66,7 2 50 5 100 11 78,6 

60 --- --- 2 50 4 80 3 37,5 12 80 8 100 29 72,5 

61 --- --- 4 80 7 87,5 9 100 15 93,8 6 85,7 41 91,1 

62 --- --- 2 40 4 44,4 2 50 6 75 7 100 33 63,6 

63 --- --- --- --- 12 50 15 60 28 80 27 90 82 67,8 

64 --- --- --- --- 4 57,1 8 88,9 8 66,7 10 83,3 30 73,2 

65 --- --- 1 20 2 22,2 10 83,3 2 50 6 75 21 55,3 

66 --- --- 5 45,5 6 54,5 17 68 10 76,9 7 100 45 65,2 

67 --- --- 11 61,1 8 34,8 30 75 17 63 13 76,5 79 63,2 

68 --- --- 5 100 13 76,5 7 50 11 78,6 4 80 40 71,4 

69 --- --- --- --- 3 75 1 33,3 4 100 10 100 18 81,8 

70 --- --- 5 41,7 12 70,6 15 65,2 29 65,9 15 75 76 65,5 

71 --- --- 3 42,9 4 66,7 3 75 7 87,5 4 57,1 21 65,6 

72 --- --- --- --- --- --- --- --- 1 100 --- --- 1 50 

73 --- --- --- --- 5 83,3 4 50 6 85,7 2 100 17 68 

74 --- --- 9 69,2 20 83,3 24 68,6 31 63,3 --- --- 84 69,4 

75 --- --- 3 25 12 92,3 14 63,6 22 57,9 11 73,3 62 62 

76 --- --- 13 68,4 18 75 22 84,6 42 75 21 100 116 79,5 

77 --- --- 11 100 9 100 19 95 19 95 7 87,5 65 95,6 

78 --- --- 1 50 6 100 9 56,3 17 89,5 5 100 38 79,2 

79 --- --- 7 87,5 10 90,9 18 90 22 73,3 10 83,3 67 82,7 

80 --- --- 1 100 10 100 7 100 8 88,9 11 91,7 37 94,9 

81 --- --- 6 75 7 38,9 18 60 36 80 14 73,7 81 67,5 

82 --- --- 7 100 11 100 14 93,3 22 84,6 4 100 58 92,1 

83 6 66,7 5 41,7 28 82,4 37 88,1 62 93,9 10 90,9 148 85,1 

84 2 100 10 90,9 13 86,7 13 100 31 88,6 12 100 81 92 

85 1 100 6 100 5 100 8 100 10 83,3 2 100 32 94,1 

86 --- --- 5 71,4 10 90,9 8 88,9 13 76,5 5 100 41 82 

87 --- --- --- --- 6 60 5 41,7 22 66,7 7 77,8 40 58,8 

88 --- --- 13 56,5 23 76,7 22 71 39 84,8 19 90,5 116 74,8 

89 --- --- 2 100 3 100 7 70 14 60,9 6 75 32 69,6 

90 --- --- 3 60 7 63,6 8 61,5 26 70,3 5 100 49 69 

91 --- --- --- --- 3 60 8 57,1 7 38,9 4 80 22 46,8 

92 --- --- 8 24,2 28 63,6 25 52,1 22 59,5 20 87 103 54,2 

93 --- --- 4 15,4 16 53,3 29 60,4 60 69 25 78,1 134 54,9 

94 2 40 10 31,3 12 37,5 19 54,3 20 64,5 5 45,5 68 46,6 

95 --- --- 2 22,2 2 100 11 84,6 19 100 10 90,9 44 75,9 

96 --- --- 1 50 12 92,3 13 76,5 21 67,7 6 85,7 53 75,7 

TOTAL 23 19,8 355 48,2 877 69,9 1244 71,9 1763 71,9 995 87,4 5257 70,8 



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6.3.3 Caesarean Section Srandardized Rate by Perinatal Risk Factors 

Graph 6.3.3 corresponds to the 95% CI for the standardised caesarean section adjusted rate. 

Graph 6.3 

The results for Units 91, 92, 93 and 94 reached statistical significant relevance, being the caesarean section rate for these 

Units significantly smaller than the one expected according to the standard’s population caesarean section distribution. 

On the other hand, Units 17, 77, 82 and 84 had a bigger significant caesarean section rate than the one expected according 

to the standard’s population multiple gestation distribution. 





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6.4 Resuscitation in Delivery Room rate. 

Definition: Any respiratory support given in the delivery area. Resuscitation in Delivery Room 

rate does not consider Oxygen in Delivery Room. 

6.4.1 Resuscitation in Delivery Room Rate By Birth Weight. 

The global resuscitation in delivery room rate for 2010 cohort has been of 


Resuscitation in Delivery Area Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 1 100 7 87,5 12 80 13 61,9 10 32,3 10 52,6 53 55,8 

2 --- --- 1 100 2 66,7 1 20 6 85,7 4 44,4 14 56 

3 1 100 14 87,5 15 65,2 22 59,5 14 38,9 7 16,7 73 47,1 

4 3 100 7 87,5 7 87,5 6 37,5 5 23,8 5 35,7 33 47,1 

5 3 100 18 85,7 25 83,3 19 59,4 14 35,9 15 35,7 94 56,3 

6 4 44,4 13 81,3 24 70,6 11 40,7 9 20,5 10 23,8 71 41,3 

7 --- --- --- --- --- --- --- --- 1 50 --- --- 1 33,3 

8 --- --- --- --- 1 50 2 33,3 3 33,3 1 20 7 31,8 

9 --- --- --- --- 3 100 5 50 7 46,7 2 28,6 17 47,2 

10 1 100 7 100 5 71,4 9 56,3 2 14,3 3 18,8 27 44,3 

11 1 100 12 92,3 20 80 16 48,5 14 29,8 14 53,8 77 53,1 

12 3 100 51 91,1 62 76,5 52 52,5 55 35,5 37 42,5 260 54,1 

13 --- --- --- --- 5 100 2 100 7 58,3 1 20 15 60 

14 3 100 27 81,8 30 63,8 30 44,8 58 47,2 23 45,1 171 52,8 

15 1 100 4 66,7 20 90,9 5 71,4 29 80,6 6 54,5 65 78,3 

16 --- --- 2 100 3 75 3 75 11 57,9 11 100 30 75 

17 --- --- 9 100 14 100 24 92,3 20 71,4 11 84,6 78 86,7 

18 --- --- 1 25 5 71,4 12 52,2 8 36,4 6 46,2 32 46,4 

19 1 100 8 100 5 83,3 10 66,7 8 42,1 13 72,2 45 67,2 

20 1 100 5 100 18 100 15 93,8 17 70,8 10 66,7 66 83,5 

21 --- --- 3 100 3 60 6 54,5 7 38,9 1 25 20 48,8 

22 1 100 4 80 9 81,8 2 16,7 6 31,6 4 25 26 40,6 

23 1 100 29 93,5 39 76,5 33 57,9 21 44,7 9 33,3 132 61,7 

24 --- --- 14 53,8 28 49,1 17 34,7 18 43,9 --- --- 77 44,5 

25 --- --- --- --- 1 33,3 5 50 5 41,7 --- --- 11 44 

26 --- --- 16 84,2 12 85,7 7 50 7 31,8 --- --- 42 60,9 

27 --- --- 6 100 8 66,7 5 55,6 12 57,1 --- --- 31 64,6 

28 --- --- --- --- 4 50 1 50 --- --- --- --- 5 26,3 

29 1 100 1 100 1 33,3 2 66,7 7 77,8 --- --- 12 70,6 

30 --- --- 10 100 16 80 6 54,5 18 54,5 --- --- 50 67,6 

31 --- --- --- --- 2 66,7 2 100 1 16,7 --- --- 5 45,5 

32 2 100 6 100 7 100 7 87,5 4 44,4 --- --- 26 81,3 

33 3 75 14 77,8 20 64,5 21 61,8 24 46,2 1 100 83 59,3 

34 1 100 6 100 11 91,7 6 75 6 46,2 --- --- 30 75 

35 --- --- 5 83,3 6 75 2 66,7 4 57,1 --- --- 17 68 

36 --- --- 8 100 10 83,3 8 44,4 8 25,8 --- --- 34 49,3 

37 --- --- 2 66,7 3 100 6 54,5 8 38,1 1 100 20 51,3 

38 1 100 5 100 8 100 5 50 8 44,4 --- --- 27 64,3 

39 --- --- 5 100 17 94,4 10 83,3 11 50 1 50 44 74,6 

40 --- --- 3 75 2 40 4 50 1 7,7 --- --- 10 32,3 

41 --- --- 9 81,8 10 83,3 11 73,3 9 42,9 1 100 40 66,7 

42 --- --- 2 100 6 100 13 72,2 5 62,5 --- --- 26 76,5 

43 --- --- 2 100 6 66,7 7 63,6 8 26,7 --- --- 23 44,2 

44 --- --- 4 66,7 7 77,8 6 50 8 32 --- --- 25 48,1 

45 --- --- 5 100 6 85,7 7 58,3 4 25 --- --- 22 55 

46 1 100 2 100 --- --- 4 80 2 66,7 --- --- 9 81,8 



EuroNeoNet 


Resuscitation in Delivery Area Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

47 --- --- 3 100 4 100 2 33,3 7 46,7 --- --- 16 57,1 

48 --- --- 1 100 4 80 2 50 9 47,4 --- --- 16 55,2 

49 --- --- 3 100 5 100 10 100 1 25 --- --- 19 86,4 

50 --- --- 4 100 6 75 6 85,7 4 50 --- --- 20 74,1 

51 2 100 11 100 22 95,7 30 85,7 18 64,3 15 68,2 98 81 

52 1 33,3 18 94,7 28 66,7 17 45,9 21 42,9 --- --- 85 56,7 

53 --- --- 4 66,7 5 83,3 3 60 7 53,8 --- --- 19 63,3 

54 1 100 3 100 --- --- 1 50 1 14,3 --- --- 6 46,2 

55 --- --- 20 100 32 88,9 45 75 22 32,4 --- --- 119 64,7 

56 --- --- --- --- 4 100 2 33,3 1 14,3 --- --- 7 41,2 

57 --- --- 7 87,5 9 81,8 6 50 15 65,2 --- --- 37 68,5 

58 --- --- 4 100 13 100 14 77,8 15 57,7 --- --- 46 75,4 

59 --- --- 2 100 1 50 1 33,3 3 42,9 --- --- 7 50 

60 --- --- 4 100 7 100 9 69,2 5 31,3 --- --- 25 62,5 

61 --- --- 7 77,8 5 55,6 11 78,6 7 53,8 --- --- 30 66,7 

62 1 100 5 71,4 3 50 3 33,3 2 20 --- --- 14 42,4 

63 --- --- 7 87,5 18 75 24 60 23 46,9 --- --- 72 59,5 

64 --- --- 1 100 3 60 7 58,3 5 21,7 --- --- 16 39 

65 --- --- 4 66,7 5 62,5 6 60 5 35,7 --- --- 20 52,6 

66 1 100 4 80 22 88 13 61,9 9 52,9 --- --- 49 71 

67 --- --- 14 77,8 27 90 23 71,9 20 45,5 1 100 85 68 

68 --- --- 11 100 12 100 9 50 8 53,3 --- --- 40 71,4 

69 --- --- 3 100 1 100 3 60 5 41,7 --- --- 12 57,1 

70 --- --- 6 100 24 96 17 85 23 60,5 20 74,1 90 77,6 

71 --- --- 8 100 4 66,7 4 66,7 2 16,7 --- --- 18 56,3 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 1 100 3 100 5 100 6 46,2 --- --- --- --- 15 60 

74 2 100 17 100 23 95,8 23 100 26 100 29 100 120 99,2 

75 1 100 12 100 10 83,3 19 67,9 24 88,9 14 70 80 80 

76 4 100 20 95,2 28 100 23 76,7 22 66,7 17 56,7 114 78,1 

77 3 100 9 100 10 90,9 11 84,6 19 79,2 7 87,5 59 86,8 

78 --- --- 3 50 2 50 3 21,4 3 23,1 5 50 16 33,3 

79 1 100 11 100 8 100 15 88,2 23 88,5 16 88,9 74 91,4 

80 --- --- 3 100 8 72,7 5 83,3 4 25 3 100 23 59 

81 2 100 9 90 14 66,7 16 72,7 17 40,5 12 52,2 70 58,3 

82 1 100 5 100 11 100 5 41,7 4 21,1 6 40 32 50,8 

83 7 100 25 100 25 86,2 27 84,4 27 62,8 20 52,6 131 75,3 

84 3 100 9 100 18 100 16 100 39 92,9 --- --- 85 96,6 

85 1 100 4 100 8 100 3 60 7 53,8 --- --- 23 67,6 

86 --- --- 5 100 17 94,4 3 50 12 80 4 66,7 41 82 

87 2 100 3 100 4 100 15 75 14 60,9 9 56,3 47 69,1 

88 2 100 27 100 26 100 32 91,4 25 64,1 21 80,8 133 85,8 

89 --- --- 2 100 3 100 8 61,5 5 41,7 6 37,5 24 52,2 

90 --- --- 4 100 8 88,9 8 72,7 15 60 11 50 46 64,8 

91 --- --- 5 100 5 100 7 77,8 11 68,8 6 50 34 72,3 

92 1 100 34 97,1 42 100 45 88,2 35 59,3 1 50 158 83,2 

93 8 57,1 37 100 35 100 45 95,7 54 90 49 96,1 228 93,4 

94 11 100 26 100 31 79,5 18 60 8 32 3 20 97 66,4 

95 1 100 9 100 9 100 4 100 7 100 8 100 38 100 

96 --- --- 2 100 17 100 12 92,3 15 68,2 13 81,3 59 84,3 

TOTAL 91 84,3 785 90,9 1149 82 1098 64,5 1164 48,6 503 53,7 4790 64,6 



EuroNeoNet 


6.4.2 Resuscitation in Delivery Room Rate by Gestational Age. 

Table 6.4.2 shows the Resuscitation in Delivery Room distribution according 

to GA for each Unit. 

Resuscitation in Delivery Area Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 2 100 10 100 14 82,4 9 40,9 15 45,5 3 27,3 53 55,8 

2 --- --- 2 100 --- --- 3 75 7 50 2 40 14 56 

3 5 100 13 92,9 14 73,7 18 54,5 21 30 2 14,3 73 47,1 

4 3 100 8 100 6 54,5 5 35,7 11 40,7 --- --- 33 47,1 

5 8 88,9 11 100 34 85 14 50 23 33,8 4 36,4 94 56,3 

6 3 37,5 17 89,5 21 72,4 16 41 11 17,7 3 20 71 41,3 

7 --- --- --- --- --- --- --- --- 1 50 --- --- 1 33,3 

8 --- --- --- --- --- --- 1 50 5 38,5 1 14,3 7 31,8 

9 --- --- 2 100 4 66,7 5 55,6 5 38,5 1 20 17 47,2 

10 1 100 7 100 4 100 9 64,3 6 21,4 --- --- 27 44,3 

11 --- --- 13 100 13 68,4 20 54,1 24 46,2 7 29,2 77 53,1 

12 1 100 36 97,3 56 83,6 77 66,4 67 38,1 23 27,4 260 54,1 

13 --- --- 1 100 2 100 6 85,7 4 44,4 2 33,3 15 60 

14 1 100 14 87,5 29 82,9 48 59,3 54 42,9 25 38,5 171 52,8 

15 --- --- 4 100 13 86,7 16 94,1 18 72 14 63,6 65 78,3 

16 1 100 1 100 3 75 2 50 14 77,8 9 75 30 75 

17 --- --- 3 100 16 100 23 100 27 87,1 9 52,9 78 86,7 

18 --- --- 2 50 8 72,7 6 37,5 13 50 3 25 32 46,4 

19 --- --- 8 100 3 75 14 87,5 17 60,7 3 27,3 45 67,2 

20 --- --- 8 100 17 100 9 90 24 77,4 8 61,5 66 83,5 

21 --- --- 3 100 3 60 4 66,7 10 47,6 --- --- 20 48,8 

22 --- --- 7 100 6 66,7 5 33,3 6 26,1 2 20 26 40,6 

23 1 100 29 100 34 85 33 53,2 29 44,6 6 35,3 132 61,7 

24 1 100 15 100 18 36,7 27 45 16 33,3 --- --- 77 44,5 

25 --- --- --- --- 2 100 6 50 1 25 2 28,6 11 44 

26 2 100 10 100 13 86,7 8 57,1 7 36,8 2 22,2 42 60,9 

27 --- --- 2 100 10 83,3 14 70 4 50 1 16,7 31 64,6 

28 --- --- --- --- 3 60 2 50 --- --- --- --- 5 26,3 

29 --- --- 1 50 2 100 5 83,3 3 75 1 33,3 12 70,6 

30 2 100 12 100 12 75 6 60 9 50 9 56,3 50 67,6 

31 --- --- --- --- --- --- 2 100 2 66,7 1 20 5 45,5 

32 1 100 7 100 7 100 7 100 3 60 1 20 26 81,3 

33 --- --- 14 82,4 20 71,4 16 66,7 27 54 6 30 83 59,3 

34 --- --- 6 100 12 100 4 57,1 6 85,7 2 25 30 75 

35 --- --- 3 100 6 85,7 3 60 5 83,3 --- --- 17 68 

36 --- --- 8 100 7 87,5 10 62,5 6 31,6 3 16,7 34 49,3 

37 --- --- 1 33,3 3 75 4 57,1 7 46,7 5 50 20 51,3 

38 --- --- 3 100 7 100 8 72,7 8 72,7 1 10 27 64,3 

39 2 100 2 100 14 93,3 11 68,8 8 80 7 50 44 74,6 

40 1 100 --- --- 2 66,7 4 40 2 20 1 14,3 10 32,3 

41 --- --- 7 100 6 66,7 13 76,5 8 66,7 6 40 40 66,7 

42 --- --- 2 100 9 100 8 100 4 44,4 3 50 26 76,5 

43 --- --- 6 100 2 66,7 5 83,3 6 35,3 4 20 23 44,2 

44 --- --- 3 75 5 62,5 5 41,7 2 22,2 10 52,6 25 48,1 

45 --- --- 3 100 2 66,7 11 64,7 2 28,6 4 40 22 55 

46 1 100 --- --- 1 100 4 80 3 100 --- --- 9 81,8 



EuroNeoNet 


Resuscitation in Delivery Area Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

47 --- --- 2 100 4 80 4 57,1 4 50 2 33,3 16 57,1 

48 --- --- --- --- 4 80 6 60 3 42,9 3 42,9 16 55,2 

49 --- --- 1 100 8 100 6 100 4 57,1 --- --- 19 86,4 

50 --- --- 4 100 6 100 5 71,4 5 71,4 --- --- 20 74,1 

51 4 100 15 100 17 94,4 25 89,3 27 69,2 10 58,8 98 81 

52 2 100 23 85,2 19 79,2 17 53,1 14 36,8 10 37 85 56,7 

53 --- --- 3 100 6 75 5 100 3 33,3 2 40 19 63,3 

54 --- --- 3 100 1 100 --- --- 1 20 1 25 6 46,2 

55 2 100 14 100 50 98 29 67,4 20 47,6 4 12,5 119 64,7 

56 --- --- 3 100 1 50 3 60 --- --- --- --- 7 41,2 

57 2 66,7 5 100 9 100 9 69,2 5 50 7 50 37 68,5 

58 1 100 5 100 8 100 8 72,7 16 80 8 50 46 75,4 

59 --- --- 1 100 1 100 2 66,7 1 25 2 40 7 50 

60 --- --- 4 100 5 100 3 37,5 10 66,7 3 37,5 25 62,5 

61 --- --- 5 100 3 37,5 8 88,9 12 75 2 28,6 30 66,7 

62 --- --- 4 80 3 33,3 3 75 3 37,5 1 14,3 14 42,4 

63 --- --- 6 85,7 19 79,2 21 84 14 40 12 40 72 59,5 

64 --- --- 1 100 5 71,4 4 44,4 3 25 3 25 16 39 

65 --- --- 2 40 7 77,8 9 75 1 25 1 12,5 20 52,6 

66 2 100 9 81,8 10 90,9 19 76 6 46,2 3 42,9 49 71 

67 --- --- 15 83,3 22 95,7 30 75 12 44,4 6 35,3 85 68 

68 1 100 5 100 15 88,2 8 57,1 7 50 4 80 40 71,4 

69 1 100 --- --- 4 100 1 33,3 2 66,7 4 40 12 57,1 

70 --- --- 12 100 15 88,2 22 95,7 32 72,7 9 45 90 77,6 

71 --- --- 6 85,7 6 100 1 25 4 50 1 14,3 18 56,3 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- 2 100 5 83,3 6 75 2 28,6 --- --- 15 60 

74 --- --- 13 100 23 95,8 35 100 49 100 --- --- 120 99,2 

75 --- --- 12 100 11 84,6 16 72,7 28 73,7 13 86,7 80 80 

76 --- --- 19 100 23 95,8 25 96,2 37 66,1 10 47,6 114 78,1 

77 --- --- 11 100 9 100 18 90 16 80 5 62,5 59 86,8 

78 --- --- 1 50 2 33,3 9 56,3 4 21,1 --- --- 16 33,3 

79 --- --- 8 100 11 100 20 100 28 93,3 7 58,3 74 91,4 

80 --- --- 1 100 8 80 4 57,1 6 66,7 4 33,3 23 59 

81 --- --- 8 100 14 77,8 17 56,7 23 51,1 8 42,1 70 58,3 

82 --- --- 7 100 10 90,9 7 46,7 8 30,8 --- --- 32 50,8 

83 9 100 12 100 32 94,1 32 76,2 38 57,6 8 72,7 131 75,3 

84 2 100 11 100 15 100 13 100 35 100 9 75 85 96,6 

85 1 100 6 100 5 100 8 100 3 25 --- --- 23 67,6 

86 1 100 7 100 10 90,9 8 88,9 13 76,5 2 40 41 82 

87 3 100 1 100 9 90 9 75 21 63,6 4 44,4 47 69,1 

88 4 100 23 100 30 100 30 96,8 37 80,4 9 42,9 133 85,8 

89 --- --- 2 100 3 100 7 70 9 39,1 3 37,5 24 52,2 

90 --- --- 5 100 11 100 9 69,2 19 51,4 2 40 46 64,8 

91 1 100 4 100 4 80 12 85,7 9 50 4 80 34 72,3 

92 5 100 33 100 44 100 42 87,5 25 67,6 9 39,1 158 83,2 

93 16 76,2 25 96,2 31 100 46 97,9 84 96,6 26 81,3 228 93,4 

94 5 100 30 93,8 24 75 26 74,3 9 29 3 27,3 97 66,4 

95 3 100 9 100 2 100 10 100 12 100 2 100 38 100 

96 --- --- 2 100 13 100 17 100 23 74,2 4 57,1 59 84,3 

TOTAL 101 87,8 704 95,4 1060 84,1 1201 69,6 1298 53,1 426 37,8 4790 64,6 



EuroNeoNet 


6.4.3 Resuscitation in Delivery Room Rate by Perinatal Risk Factors 

Graph 6.4.3, corresponds to the 95% CI for the standardised resuscitation in delivery room adjusted rate. 

Graph 6.4.3 

The results for Units 3, 6, 8, 10, 12, 14, 22, 24, 28, 40, 64 and 78 reached statistical significant relevance, being the 

resuscitation in delivery room rate for these Units significantly smaller than the one expected according to the standard’s 

population resuscitation in delivery room distribution. On the other hand, Units 17, 51, 74, 77, 79, 84, 88, 92 and 93 had a 

bigger significant resuscitation in delivery room rate than the one expected according to the standard’s population 

resuscitation in delivery room distribution. 





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6.5 Surfactant at any Time Rate. 

Definition: exogenous surfactant given to the infant at any time. 

6.5.1 Surfactant at any time Rate by Birth Weight. 

The global surfactant at any time rate for 2010 cohort has been of 48.3%, with a 

variation of 18% and 81.5% within units. 

Unit 

Code 

Surfactant at Any Time Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 1 100 6 75 11 73,3 8 38,1 5 16,1 5 26,3 36 37,9 

2 --- --- 1 100 1 33,3 1 20 1 14,3 2 22,2 6 24 

3 1 100 14 87,5 15 65,2 15 40,5 7 19,4 3 7,1 55 35,5 

4 3 100 8 100 5 62,5 4 25 2 9,5 1 7,1 23 32,9 

5 3 100 17 81 24 80 15 46,9 5 12,8 2 4,8 66 39,5 

6 5 55,6 12 75 17 50 4 14,8 7 15,9 1 2,4 46 26,7 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- 2 100 3 50 2 22,2 --- --- 7 31,8 

9 1 100 --- --- 3 100 10 100 6 40 2 28,6 22 61,1 

10 1 100 7 100 6 85,7 11 68,8 4 28,6 6 37,5 35 57,4 

11 1 100 11 84,6 19 76 8 24,2 14 29,8 2 7,7 55 37,9 

12 3 100 54 96,4 64 79 53 53,5 55 35,5 34 39,1 263 54,7 

13 --- --- --- --- 4 80 2 100 2 16,7 1 20 9 36 

14 3 100 29 87,9 31 66 36 53,7 33 26,8 15 29,4 147 45,4 

15 1 100 5 83,3 17 77,3 1 14,3 11 30,6 5 45,5 40 48,2 

16 --- --- 2 100 3 75 1 25 5 26,3 3 27,3 14 35 

17 --- --- 9 100 8 57,1 12 46,2 8 28,6 7 53,8 44 48,9 

18 --- --- --- --- 4 57,1 10 43,5 9 40,9 4 30,8 27 39,1 

19 1 100 6 75 5 83,3 4 26,7 4 21,1 5 27,8 25 37,3 

20 --- --- 5 100 11 61,1 6 37,5 8 33,3 7 46,7 37 46,8 

21 --- --- 3 100 5 100 7 63,6 10 55,6 2 50 27 65,9 

22 1 100 4 80 8 72,7 8 66,7 5 26,3 7 43,8 33 51,6 

23 1 100 31 100 41 82 42 73,7 22 45,8 10 37 147 68,7 

24 --- --- 24 92,3 42 73,7 27 55,1 16 39 --- --- 109 63 

25 --- --- --- --- 2 66,7 5 50 1 8,3 --- --- 8 32 

26 --- --- 16 84,2 14 100 4 28,6 5 22,7 --- --- 39 56,5 

27 --- --- 5 83,3 10 83,3 6 66,7 14 66,7 --- --- 35 72,9 

28 --- --- --- --- 5 62,5 --- --- --- --- --- --- 5 26,3 

29 1 100 1 100 1 33,3 --- --- 3 33,3 --- --- 6 35,3 

30 --- --- 9 90 14 70 1 9,1 6 18,2 --- --- 30 40,5 

31 --- --- --- --- 1 33 1 50 --- --- --- --- 2 18,2 

32 2 100 6 100 4 57,1 6 75 1 11,1 --- --- 19 59,4 

33 3 75 15 83,3 18 58,1 12 35,3 14 26,9 --- --- 62 44,3 

34 1 100 5 83,3 12 100 4 40 1 7,7 --- --- 23 54,8 

35 1 100 6 100 8 100 1 33,3 2 28,6 --- --- 18 72 

36 --- --- 8 100 9 75 10 55,6 10 32,3 --- --- 37 53,6 

37 --- --- 3 100 1 33,3 4 36,4 5 23,8 1 100 14 35,9 

38 1 100 5 100 6 75 6 60 4 22,2 --- --- 22 52,4 

39 --- --- 5 100 15 83,3 6 50 2 9,1 1 50 29 49,2 

40 --- --- 3 75 2 40 5 62,5 2 15,4 1 100 13 41,9 

41 --- --- 4 36,4 9 75 6 40 5 23,8 1 100 25 41,7 

42 --- --- --- --- 6 100 8 44,4 1 12,5 --- --- 15 44,1 

43 --- --- 1 50 4 44,4 3 27,3 3 10 --- --- 11 21,2 

44 --- --- 6 100 6 66,7 2 16,7 5 20 --- --- 19 36,5 

45 --- --- 5 100 4 57,1 6 50 2 12,5 --- --- 17 42,5 

46 1 100 2 100 --- --- 3 60 2 66,7 --- --- 8 72,7 



EuroNeoNet 


Unit 

Code 

Surfactant at Any Time Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

47 --- --- 3 100 2 50 4 66,7 5 33,3 --- --- 14 50 

48 --- --- 1 100 3 60 2 50 6 31,6 --- --- 12 41,4 

49 --- --- 3 100 4 80 6 60 2 50 --- --- 15 68,2 

50 --- --- 4 100 8 100 3 42,9 3 37,5 --- --- 18 66,7 

51 2 100 11 100 22 95,7 17 48,6 9 32,1 7 31,8 68 56,2 

52 2 66,7 16 84,2 29 69 15 40,5 18 36,7 --- --- 80 53,3 

53 --- --- 4 66,7 5 83,3 1 20 4 30,8 --- --- 14 46,7 

54 1 100 3 100 --- --- 1 50 2 28,6 --- --- 7 53,8 

55 --- --- 20 100 33 91,7 42 70 19 27,5 --- --- 114 61,6 

56 --- --- --- --- 4 100 6 100 3 42,9 --- --- 13 76,5 

57 --- --- 8 100 8 72,7 6 50 9 39,1 --- --- 31 57,4 

58 --- --- 2 50 4 30,8 2 11,1 3 11,5 --- --- 11 18 

59 --- --- 2 100 1 50 --- --- 1 14,3 --- --- 4 28,6 

60 --- --- 3 75 6 85,7 6 46,2 6 37,5 --- --- 21 52,5 

61 --- --- 3 33,3 5 55,6 7 50 6 46,2 --- --- 21 46,7 

62 1 100 5 71,4 4 66,7 4 44,4 --- --- --- --- 14 42,4 

63 --- --- 8 100 20 83,3 20 50 18 36,7 --- --- 66 54,5 

64 --- --- --- --- 2 40 4 33,3 3 13 --- --- 9 22 

65 --- --- 3 50 6 75 4 40 4 28,6 --- --- 17 44,7 

66 1 100 5 100 24 96 18 85,7 7 41,2 --- --- 55 79,7 

67 --- --- 9 50 21 70 4 12,5 13 29,5 1 100 48 38,4 

68 --- --- 11 100 11 91,7 10 55,6 11 73,3 --- --- 43 76,8 

69 --- --- 3 100 1 100 1 16,7 2 16,7 --- --- 7 31,8 

70 --- --- 3 50 10 40 3 15 8 21,1 3 11,1 27 23,3 

71 --- --- 5 62,5 3 50 4 66,7 3 25 --- --- 15 46,9 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 1 100 3 100 5 100 9 69,2 --- --- --- --- 18 72 

74 1 50 14 82,4 17 70,8 12 52,2 9 34,6 8 27,6 61 50,4 

75 1 100 8 66,7 8 66,7 3 10,7 7 25,9 2 10 29 29 

76 4 100 18 85,7 20 71,4 15 50 7 21,2 8 26,7 72 49,3 

77 3 100 6 66,7 7 63,6 5 38,5 5 20,8 --- --- 26 38,2 

78 --- --- 5 83,3 2 50 3 21,4 3 23,1 1 10 14 29,2 

79 1 100 9 81,8 8 100 8 47,1 12 46,2 9 50 47 58 

80 --- --- 3 100 9 81,8 3 50 6 37,5 1 33,3 22 56,4 

81 1 50 7 70 13 61,9 8 36,4 8 19 5 21,7 42 35 

82 1 100 5 100 9 81,8 6 50 7 36,8 1 6,7 29 46 

83 4 57,1 19 76 13 44,8 20 62,5 13 30,2 7 18,4 76 43,7 

84 3 100 8 88,9 16 88,9 9 56,3 13 31 --- --- 49 55,7 

85 1 100 3 75 7 87,5 3 60 8 61,5 --- --- 22 64,7 

86 --- --- 4 80 13 72,2 3 50 4 26,7 --- --- 24 48 

87 2 100 3 100 4 100 10 50 3 13 2 12,5 24 35,3 

88 2 100 27 100 26 100 26 74,3 10 25,6 12 46,2 103 66,5 

89 --- --- 2 100 3 100 6 46,2 2 16,7 6 37,5 19 41,3 

90 --- --- 4 100 8 88,9 4 36,4 8 32 5 22,7 29 40,8 

91 --- --- 5 100 3 60 5 55,6 6 37,5 3 25 22 46,8 

92 1 100 31 88,6 40 95,2 43 86 37 62,7 2 100 154 81,5 

93 --- --- 30 81,1 18 51,4 22 46,8 15 25 12 23,5 97 39,8 

94 9 81,8 16 61,5 20 51,3 8 26,7 9 36 4 26,7 66 45,2 

95 --- --- 8 80 8 66,7 2 28,6 6 35,3 6 54,5 30 51,7 

96 --- --- 2 100 17 100 10 76,9 5 22,7 6 37,5 40 57,1 

TOTAL 78 72,2 728 84,2 1027 73,1 821 48,1 697 28,9 239 25,4 3590 48,3 



EuroNeoNet 


6.5.2 Surfactant at any time Rate by Gestational Age. 

Table 6.5.2 shows the Surfactant at any Time distribution according to 

gestational age for each Unit. 

Unit 

Code 

Surfactant at Any Time Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 2 100 10 100 12 70,6 5 22,7 7 21,2 --- --- 36 37,9 

2 --- --- 2 100 --- --- 1 25 3 21,4 --- --- 6 24 

3 5 100 13 92,9 14 73,7 15 45,5 8 11,4 --- --- 55 35,5 

4 3 100 8 100 7 63,6 1 7,1 4 14,8 --- --- 23 32,9 

5 8 88,9 11 100 32 80 8 28,6 7 10,3 --- --- 66 39,5 

6 3 37,5 17 89,5 12 41,4 13 33,3 1 1,6 --- --- 46 26,7 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 2 100 5 38,5 --- --- 7 31,8 

9 1 100 2 100 6 100 8 88,9 5 38,5 --- --- 22 61,1 

10 1 100 7 100 4 100 14 100 9 32,1 --- --- 35 57,4 

11 --- --- 13 100 11 57,9 20 54,1 8 15,4 3 12,5 55 37,9 

12 1 100 36 97,3 63 94 90 77,6 67 38,1 6 7,1 263 54,7 

13 --- --- 1 100 2 100 2 28,6 4 44,4 --- --- 9 36 

14 1 100 16 100 31 88,6 50 61,7 42 33,3 7 10,8 147 45,4 

15 --- --- 4 100 13 86,7 11 64,7 12 48 --- --- 40 48,2 

16 1 100 1 100 2 50 2 50 5 27,8 3 25 14 35 

17 --- --- 3 100 13 81,3 17 73,9 10 32,3 1 5,9 44 48,9 

18 --- --- 2 50 6 54,5 8 50 11 42,3 --- --- 27 39,1 

19 --- --- 6 75 3 75 9 56,3 6 21,4 1 9,1 25 37,3 

20 --- --- 7 87,5 12 70,6 4 40 13 41,9 1 7,7 37 46,8 

21 --- --- 3 100 5 100 5 83,3 14 66,7 --- --- 27 65,9 

22 --- --- 6 85,7 7 77,8 10 66,7 9 39,1 1 10 33 51,6 

23 1 100 29 100 37 94,9 38 61,3 33 50 9 52,9 147 68,7 

24 1 100 15 100 41 83,7 42 70 10 20,8 --- --- 109 63 

25 --- --- --- --- 2 100 6 50 --- --- --- --- 8 32 

26 2 100 10 100 15 100 6 42,9 6 31,6 --- --- 39 56,5 

27 --- --- 2 100 11 91,7 17 85 5 62,5 --- --- 35 72,9 

28 --- --- --- --- 4 80 --- --- 1 16,7 --- --- 5 26,3 

29 --- --- 2 100 1 50 2 33,3 1 25 --- --- 6 35,3 

30 2 100 12 100 10 62,5 4 40 2 11,1 --- --- 30 40,5 

31 --- --- --- --- --- --- 1 50 1 33,3 --- --- 2 18,2 

32 1 100 7 100 5 71,4 4 57,1 1 20 1 20 19 59,4 

33 1 100 16 94,1 18 64,3 10 41,7 15 30 2 10 62 44,3 

34 --- --- 6 100 11 91,7 4 50 1 14,3 1 11,1 23 54,8 

35 --- --- 3 100 7 100 4 80 4 66,7 --- --- 18 72 

36 --- --- 8 100 8 100 7 43,8 13 68,4 1 5,6 37 53,6 

37 --- --- 3 100 2 50 4 57,1 4 26,7 1 10 14 35,9 

38 --- --- 3 100 7 100 6 54,5 6 54,5 --- --- 22 52,4 

39 2 100 2 100 14 93,3 8 50 2 20 1 7,1 29 49,2 

40 1 100 --- --- 2 66,7 7 70 2 20 1 14,3 13 41,9 

41 --- --- 3 42,9 7 77,8 10 58,8 3 25 2 13,3 25 41,7 

42 --- --- 2 100 6 66,7 5 62,5 2 22,2 --- --- 15 44,1 

43 --- --- 5 83,3 1 33,3 2 33,3 2 11,8 1 5 11 21,2 

44 --- --- 4 100 6 75 5 41,7 4 44,4 --- --- 19 36,5 

45 --- --- 3 100 3 100 10 58,8 --- --- 1 10 17 42,5 



EuroNeoNet 


Unit 

Code 

Surfactant at Any Time Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 1 100 --- --- 1 100 3 60 3 100 --- --- 8 72,7 

47 --- --- 2 100 4 80 5 71,4 3 37,5 --- --- 14 50 

48 --- --- --- --- 4 80 5 50 3 42,9 --- --- 12 41,4 

49 --- --- 1 100 7 87,5 5 83,3 2 28,6 --- --- 15 68,2 

50 --- --- 4 100 6 100 5 71,4 3 42,9 --- --- 18 66,7 

51 3 75 15 100 17 94,4 16 57,1 16 41 1 5,9 68 56,2 

52 2 100 24 88,9 19 79,2 13 40,6 18 47,4 4 14,8 80 53,3 

53 --- --- 3 100 5 62,5 3 60 2 22,2 1 20 14 46,7 

54 --- --- 3 100 1 100 --- --- 1 20 2 50 7 53,8 

55 2 100 14 100 48 94,1 31 70,5 18 42,9 1 3,1 114 61,6 

56 --- --- 3 100 2 100 5 100 2 66,7 1 25 13 76,5 

57 3 100 5 100 9 100 7 53,8 5 50 2 14,3 31 57,4 

58 1 100 3 60 3 37,5 2 18,2 2 10 --- --- 11 18 

59 --- --- 1 100 1 100 1 33,3 1 25 --- --- 4 28,6 

60 --- --- 4 100 5 100 2 25 10 66,7 --- --- 21 52,5 

61 --- --- 2 40 5 62,5 7 77,8 6 37,5 1 14,3 21 46,7 

62 --- --- 3 60 7 77,8 3 75 1 12,5 --- --- 14 42,4 

63 --- --- 7 100 22 91,7 20 80 13 37,1 4 13,3 66 54,5 

64 --- --- 1 100 4 57,1 2 22,2 2 16,7 --- --- 9 22 

65 --- --- 3 60 7 77,8 6 50 --- --- 1 12,5 17 44,7 

66 2 100 11 100 11 100 23 92 8 61,5 --- --- 55 79,7 

67 --- --- 13 72,2 13 56,5 16 40 6 22,2 --- --- 48 38,4 

68 1 100 5 100 16 94,1 11 78,6 9 64,3 1 20 43 76,8 

69 1 100 --- --- 4 100 1 33,3 1 25 --- --- 7 31,8 

70 --- --- 6 50 6 35,3 9 39,1 6 13,6 --- --- 27 23,3 

71 --- --- 5 71,4 3 50 4 100 2 25 1 14,3 15 46,9 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- 2 100 5 83,3 7 87,5 4 57,1 --- --- 18 72 

74 --- --- 11 84,6 20 83,3 17 48,6 13 26,5 --- --- 61 50,4 

75 --- --- 8 66,7 8 61,5 7 31,8 6 15,8 --- --- 29 29 

76 --- --- 19 100 18 75 15 57,7 18 32,1 2 9,5 72 49,3 

77 --- --- 9 81,8 6 66,7 7 35 4 20 --- --- 26 38,2 

78 --- --- 1 50 4 66,7 6 37,5 3 15,8 --- --- 14 29,2 

79 --- --- 8 100 10 90,9 15 75 14 46,7 --- --- 47 58 

80 --- --- 1 100 10 100 4 57,1 6 66,7 1 8,3 22 56,4 

81 --- --- 6 75 15 83,3 12 40 9 20 --- --- 42 35 

82 --- --- 7 100 10 90,9 9 60 3 11,5 --- --- 29 46 

83 9 100 10 83,3 21 61,8 21 50 14 21,2 1 9,1 76 43,7 

84 2 100 11 100 13 86,7 9 69,2 14 40 --- --- 49 55,7 

85 1 100 5 83,3 4 80 7 87,5 5 41,7 --- --- 22 64,7 

86 1 100 7 100 8 72,7 3 33,3 4 23,5 1 20 24 48 

87 3 100 1 100 9 90 4 33,3 7 21,2 --- --- 24 35,3 

88 4 100 23 100 30 100 29 93,5 17 37 --- --- 103 66,5 

89 --- --- 2 100 2 66,7 7 70 8 34,8 --- --- 19 41,3 

90 --- --- 5 100 9 81,8 6 46,2 9 24,3 --- --- 29 40,8 

91 1 100 4 100 4 80 8 57,1 5 27,8 --- --- 22 46,8 

92 5 100 32 97 41 95,3 45 93,8 27 73 4 17,4 154 81,5 

93 7 33,3 23 88,5 21 67,7 20 42,6 25 28,7 1 3,1 97 39,8 

94 5 100 23 71,9 14 43,8 14 40 7 22,6 3 27,3 66 45,2 

95 1 25 9 100 2 100 8 61,5 9 47,4 1 9,1 30 51,7 

96 --- --- 2 100 13 100 13 76,5 11 35,5 1 14,3 40 57,1 

TOTAL 92 79,3 670 90,8 1000 79,5 996 57,5 753 30,7 79 6,9 3590 48,3 



EuroNeoNet 


6.5.3 Surfactant at any time Standardized Rate by Perinatal Risk Factors. 

Graph 6.5.3, corresponds to the 95% CI for the standardised surfactant at any time adjusted rate. 

Graph 6.5.3 

The results for Units 2, 3, 4, 6, 31, 43, 58, 64, 70, 75, 78 and 81 reached statistical significant relevance, being the surfactant 

at any time rate for these Units significantly smaller than the one expected according to the standard’s population 

surfactant at any time distribution. On the other hand, Units 23, 24, 27, 55, 66, 68, 88 and 92 had a bigger significant 

surfactant at any time rate than the one expected according to the standard’s population surfactant at any time 

distribution. 





EuroNeoNet 


6.6 Surfactant within the First hour of Life Rate. 

Definition: Surfactant administrated within the first hour of life. No surfactant administration was 

considered as a NO. 

Note: In this section Units NOT RECORDING time of administration have been 

excluded. 

6.6.1 Surfactant within the First hour of Life Rate By Birth Weight. 

The global surfactant within the first hour of life rate for 2010 cohort has been of 

27.5%, with a variation of 1% and 77.2% within units. 

Unit 

Code 

Surfactant within the First Hour of Life Rate against 

Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 1 100 6 75 8 53,3 5 23,8 2 6,5 3 15,8 25 26,3 

2 --- --- 1 100 1 33,3 --- --- 1 14,3 --- --- 3 12 

3 1 100 11 68,8 12 52,2 10 27 3 8,3 2 4,8 39 25,2 

4 3 100 7 87,5 3 37,5 1 6,3 --- --- --- --- 14 20 

5 3 100 16 76,2 19 63,3 12 37,5 3 7,7 --- --- 53 31,7 

6 3 33,3 9 56,3 13 38,2 2 7,4 3 6,8 1 2,4 31 18 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- 2 100 2 33,3 --- --- --- --- 4 18,2 

9 --- --- --- --- --- --- 5 50 2 13,3 2 28,6 9 25 

10 1 100 4 57,1 4 57,1 9 56,3 --- --- 1 6,3 19 31,1 

11 --- --- 6 46,2 9 36 1 3 4 8,5 --- --- 20 13,8 

12 2 66,7 39 70,9 36 46,8 26 26,5 16 10,7 15 17,6 134 28,6 

13 --- --- --- --- 2 40 --- --- --- --- --- --- 2 8 

14 2 66,7 20 60,6 18 38,3 14 20,9 17 13,8 4 8 75 23,2 

15 --- --- 4 66,7 10 45,5 --- --- 1 2,8 --- --- 15 18,1 

16 --- --- 2 100 --- --- --- --- --- --- 1 9,1 3 7,5 

17 --- --- 7 77,8 7 50 6 23,1 5 17,9 1 7,7 26 28,9 

18 --- --- --- --- 2 28,6 3 13 --- --- --- --- 5 7,2 

19 1 100 5 62,5 4 66,7 4 26,7 4 21,1 4 22,2 22 32,8 

20 --- --- 1 20 3 16,7 --- --- 1 4,2 1 6,7 6 7,6 

21 --- --- 3 100 5 100 4 36,4 7 38,9 1 25 20 48,8 

22 1 100 4 80 5 45,5 1 8,3 1 5,3 2 12,5 14 21,9 

23 1 100 29 96,7 33 66 28 50 12 25 4 14,8 107 50,5 

24 --- --- 9 34,6 17 29,8 17 34,7 7 17,1 --- --- 50 28,9 

25 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 4 

26 --- --- 7 50 6 50 2 14,3 1 5 --- --- 16 26,7 

27 --- --- --- --- 2 33,3 2 25 7 41,2 --- --- 11 34,4 

28 --- --- --- --- 3 37,5 --- --- --- --- --- --- 3 15,8 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 7 70 8 40 1 9,1 3 9,1 --- --- 19 25,7 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 2 100 2 33,3 3 42,9 1 12,5 --- --- --- --- 8 25,8 

33 3 75 14 77,8 15 48,4 5 14,7 8 15,4 --- --- 45 32,1 

34 --- --- 4 80 9 75 2 22,2 1 7,7 --- --- 16 41 

35 --- --- 6 100 6 75 1 33,3 1 14,3 --- --- 14 56 

36 --- --- 2 100 1 20 3 27,3 1 4,5 --- --- 7 17,5 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 --- --- 5 100 4 50 2 20 2 11,1 --- --- 13 31 

39 --- --- 3 75 10 71,4 6 50 1 4,8 1 50 21 39,6 

40 --- --- 1 25 1 20 3 37,5 1 7,7 --- --- 6 20 

41 --- --- 3 27,3 1 11,1 --- --- 1 5 --- --- 5 9,3 

42 --- --- --- --- 1 20 --- --- --- --- --- --- 1 3,3 

43 --- --- 1 50 3 33,3 2 18,2 2 6,7 --- --- 8 15,4 

44 --- --- 4 66,7 2 22,2 --- --- --- --- --- --- 6 11,5 



EuroNeoNet 


Unit 

Code 

Surfactant within the First Hour of Life Rate against 

Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

45 --- --- 1 33,3 2 28,6 3 27,3 --- --- --- --- 6 17,1 

46 1 100 1 50 --- --- 1 20 --- --- --- --- 3 27,3 

47 --- --- 1 33,3 --- --- 1 16,7 --- --- --- --- 2 7,1 

48 --- --- --- --- --- --- --- --- 2 10,5 --- --- 2 6,9 

49 --- --- 3 100 2 40 3 30 --- --- --- --- 8 36,4 

50 --- --- 3 75 7 87,5 2 28,6 2 25 --- --- 14 51,9 

51 2 100 11 100 19 82,6 13 37,1 7 25 5 22,7 57 47,1 

52 --- --- 11 57,9 9 26,5 3 8,3 4 8,5 --- --- 27 19,4 

53 --- --- 2 33,3 3 50 --- --- --- --- --- --- 5 16,7 

54 --- --- 1 33,3 --- --- 1 50 1 14,3 --- --- 3 23,1 

55 --- --- 17 94,4 27 84,4 26 54,2 8 12,1 --- --- 78 47,6 

56 --- --- --- --- 4 100 5 83,3 3 42,9 --- --- 12 70,6 

57 --- --- 4 50 7 63,6 2 16,7 5 21,7 --- --- 18 33,3 

58 --- --- 2 50 2 15,4 2 11,1 --- --- --- --- 6 9,8 

59 --- --- 1 50 1 50 --- --- --- --- --- --- 2 14,3 

60 --- --- 3 75 5 71,4 6 46,2 1 6,3 --- --- 15 37,5 

61 --- --- 3 33,3 --- --- 2 18,2 2 20 --- --- 7 19,4 

62 1 100 3 42,9 2 33,3 1 11,1 --- --- --- --- 7 21,2 

63 --- --- 3 50 13 65 12 30,8 9 19,1 --- --- 37 33 

64 --- --- --- --- 2 40 3 27,3 --- --- --- --- 5 13,5 

65 --- --- 1 16,7 --- --- 2 20 1 7,1 --- --- 4 10,5 

66 1 100 1 20 10 40 7 33,3 2 11,8 --- --- 21 30,4 

67 --- --- 3 21,4 10 47,6 1 3,3 5 12,5 --- --- 19 18,1 

68 --- --- 7 63,6 9 75 8 47,1 2 16,7 --- --- 26 50 

69 --- --- 2 66,7 1 100 --- --- 1 8,3 --- --- 4 18,2 

70 --- --- 1 16,7 4 16 3 15 4 10,5 3 11,1 15 12,9 

71 --- --- 5 62,5 2 33,3 1 16,7 1 8,3 --- --- 9 28,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 1 100 1 100 4 100 4 50 --- --- --- --- 10 58,8 

74 1 50 7 41,2 8 38,1 4 17,4 --- --- 2 6,9 22 18,6 

75 --- --- --- --- --- --- --- --- --- --- 1 5 1 1 

76 4 100 17 81 17 60,7 10 33,3 5 15,2 5 16,7 58 39,7 

77 3 100 6 66,7 4 36,4 2 15,4 4 17,4 --- --- 19 28,4 

78 --- --- 1 16,7 1 25 --- --- --- --- --- --- 2 4,2 

79 --- --- 9 81,8 7 100 7 41,2 10 38,5 6 33,3 39 49,4 

80 --- --- 2 66,7 4 40 1 16,7 --- --- --- --- 7 18,4 

81 --- --- 1 10 7 33,3 4 18,2 1 2,4 --- --- 13 10,8 

82 1 100 5 100 7 63,6 3 25 4 21,1 1 6,7 21 33,3 

83 4 57,1 15 60 6 20,7 11 34,4 2 4,7 1 2,6 39 22,4 

84 3 100 8 88,9 10 55,6 5 31,3 5 11,9 --- --- 31 35,2 

85 1 100 3 75 3 37,5 --- --- 3 23,1 --- --- 10 29,4 

86 --- --- 4 80 8 44,4 1 16,7 3 20 --- --- 16 32 

87 1 50 3 100 4 100 6 30 --- --- --- --- 14 20,6 

88 2 100 24 88,9 23 88,5 17 48,6 5 12,8 3 12 74 48,1 

89 --- --- 1 50 3 100 3 23,1 --- --- 1 6,3 8 17,4 

90 --- --- 4 100 5 62,5 4 36,4 2 8 2 9,1 17 24,3 

91 --- --- 3 60 1 20 2 22,2 2 12,5 2 16,7 10 21,3 

92 1 100 31 88,6 39 92,9 41 82 32 54,2 2 100 146 77,2 

93 --- --- 21 60 12 36,4 9 20 8 13,3 2 3,9 52 21,8 

94 6 54,5 5 19,2 5 12,8 --- --- --- --- --- --- 16 11 

95 --- --- 7 70 7 58,3 1 14,3 1 5,9 4 36,4 20 34,5 

96 --- --- 2 100 16 94,1 8 61,5 4 18,2 2 12,5 32 45,7 

TOTAL 57 53,8 512 61,8 631 47,2 431 26 269 11,4 85 9,1 1985 27,5 



EuroNeoNet 


6.6.2 Surfactant within the First hour of Life Rate by Gestational Age. 

Table 6.6.2 shows the surfactant within the first hour of life distribution 

according to gestational age for each Unit. 

Unit 

Code 

Surfactant Within the First Hour of Life Rate against 

Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 2 100 10 100 8 47,1 1 4,5 4 12,1 --- --- 25 26,3 

2 --- --- 2 100 --- --- --- --- 1 7,1 --- --- 3 12 

3 4 80 12 85,7 12 63,2 8 24,2 3 4,3 --- --- 39 25,2 

4 3 100 8 100 3 27,3 --- --- --- --- --- --- 14 20 

5 7 77,8 11 100 28 70 3 10,7 4 5,9 --- --- 53 31,7 

6 3 37,5 12 63,2 9 31 6 15,4 1 1,6 --- --- 31 18 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 2 100 2 15,4 --- --- 4 18,2 

9 --- --- --- --- 5 83,3 1 11,1 3 23,1 --- --- 9 25 

10 1 100 4 57,1 4 100 8 57,1 2 7,1 --- --- 19 31,1 

11 --- --- 9 69,2 5 26,3 4 10,8 --- --- 2 8,3 20 13,8 

12 1 100 31 83,8 35 54,7 45 40,9 20 11,6 2 2,4 134 28,6 

13 --- --- 1 100 1 50 --- --- --- --- --- --- 2 8 

14 1 100 11 68,8 21 60 23 28,4 14 11,2 5 7,7 75 23,2 

15 --- --- 4 100 8 53,3 3 17,6 --- --- --- --- 15 18,1 

16 1 100 1 100 --- --- --- --- 1 5,6 --- --- 3 7,5 

17 --- --- 3 100 12 75 10 43,5 1 3,2 --- --- 26 28,9 

18 --- --- --- --- 5 45,5 --- --- --- --- --- --- 5 7,2 

19 --- --- 5 62,5 2 50 9 56,3 5 17,9 1 9,1 22 32,8 

20 --- --- 2 25 3 17,6 --- --- 1 3,2 --- --- 6 7,6 

21 --- --- 3 100 5 100 4 66,7 8 38,1 --- --- 20 48,8 

22 --- --- 5 71,4 5 55,6 2 13,3 2 8,7 --- --- 14 21,9 

23 1 100 28 100 34 87,2 28 45,9 13 19,7 3 17,6 107 50,5 

24 --- --- 11 73,3 15 30,6 19 31,7 5 10,4 --- --- 50 28,9 

25 --- --- --- --- 1 50 --- --- --- --- --- --- 1 4 

26 --- --- 7 87,5 5 45,5 2 15,4 2 11,1 --- --- 16 26,7 

27 --- --- --- --- 2 50 8 47,1 1 20 --- --- 11 34,4 

28 --- --- --- --- 3 60 --- --- --- --- --- --- 3 15,8 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 2 100 8 66,7 6 37,5 2 20 1 5,6 --- --- 19 25,7 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 100 4 57,1 2 28,6 1 14,3 --- --- --- --- 8 25,8 

33 1 100 15 88,2 14 50 6 25 8 16 1 5 45 32,1 

34 --- --- 3 75 10 83,3 2 28,6 --- --- 1 11,1 16 41 

35 --- --- 3 100 6 85,7 2 40 3 50 --- --- 14 56 

36 --- --- 2 100 --- --- --- --- 5 45,5 --- --- 7 17,5 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 --- --- 3 100 5 71,4 4 36,4 1 9,1 --- --- 13 31 

39 1 50 1 100 10 83,3 7 46,7 2 20 --- --- 21 39,6 

40 1 100 --- --- --- --- 5 50 --- --- --- --- 6 20 

41 --- --- 2 28,6 1 14,3 2 14,3 --- --- --- --- 5 9,3 

42 --- --- 1 50 --- --- --- --- --- --- --- --- 1 3,3 

43 --- --- 4 66,7 1 33,3 1 16,7 1 5,9 1 5 8 15,4 

44 --- --- 2 50 4 50 --- --- --- --- --- --- 6 11,5 

45 --- --- 1 50 1 33,3 4 28,6 --- --- --- --- 6 17,1 

46 --- --- --- --- 1 100 1 20 1 33,3 --- --- 3 27,3 

47 --- --- 1 50 1 20 --- --- --- --- --- --- 2 7,1 

48 --- --- --- --- --- --- 2 20 --- --- --- --- 2 6,9 

49 --- --- 1 100 6 75 1 16,7 --- --- --- --- 8 36,4 

50 --- --- 4 100 5 83,3 4 57,1 1 14,3 --- --- 14 51,9 



EuroNeoNet 


Unit 

Code 

Surfactant Within the First Hour of Life Rate against 

Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

51 3 75 15 100 14 77,8 12 42,9 12 30,8 1 5,9 57 47,1 

52 2 100 11 50 7 33,3 2 6,7 3 8,1 2 7,4 27 19,4 

53 --- --- 1 33,3 3 37,5 1 20 --- --- --- --- 5 16,7 

54 --- --- 1 33,3 --- --- --- --- 1 20 1 25 3 23,1 

55 1 100 14 100 38 86,4 17 50 8 20,5 --- --- 78 47,6 

56 --- --- 3 100 2 100 5 100 1 33,3 1 25 12 70,6 

57 --- --- 5 100 7 77,8 4 30,8 1 10 1 7,1 18 33,3 

58 1 100 3 60 1 12,5 --- --- 1 5 --- --- 6 9,8 

59 --- --- 1 100 1 100 --- --- --- --- --- --- 2 14,3 

60 --- --- 4 100 4 80 2 25 5 33,3 --- --- 15 37,5 

61 --- --- 2 40 --- --- 3 50 2 14,3 --- --- 7 19,4 

62 --- --- 3 60 1 11,1 2 50 1 12,5 --- --- 7 21,2 

63 --- --- 4 66,7 12 60 15 62,5 5 15,2 1 3,4 37 33 

64 --- --- 1 100 3 50 1 12,5 --- --- --- --- 5 13,5 

65 --- --- --- --- 3 33,3 1 8,3 --- --- --- --- 4 10,5 

66 --- --- 7 63,6 6 54,5 6 24 2 15,4 --- --- 21 30,4 

67 --- --- 7 50 5 31,3 4 12,1 3 12 --- --- 19 18,1 

68 1 100 3 60 13 81,3 5 41,7 4 30,8 --- --- 26 50 

69 1 100 --- --- 3 75 --- --- --- --- --- --- 4 18,2 

70 --- --- 2 16,7 2 11,8 6 26,1 5 11,4 --- --- 15 12,9 

71 --- --- 5 71,4 3 50 --- --- --- --- 1 14,3 9 28,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 2 100 5 83,3 2 66,7 1 25 --- --- 10 58,8 

74 --- --- 6 46,2 10 47,6 4 11,4 2 4,1 --- --- 22 18,6 

75 --- --- --- --- --- --- --- --- 1 2,6 --- --- 1 1 

76 --- --- 19 100 14 58,3 12 46,2 11 19,6 2 9,5 58 39,7 

77 --- --- 8 72,7 5 55,6 4 20 2 10,5 --- --- 19 28,4 

78 --- --- --- --- 1 16,7 1 6,3 --- --- --- --- 2 4,2 

79 --- --- 8 100 9 90 12 63,2 10 33,3 --- --- 39 49,4 

80 --- --- 1 100 4 40 2 28,6 --- --- --- --- 7 18,4 

81 --- --- 2 25 7 38,9 2 6,7 2 4,4 --- --- 13 10,8 

82 --- --- 7 100 8 72,7 4 26,7 2 7,7 --- --- 21 33,3 

83 9 100 6 50 13 38,2 8 19 3 4,5 --- --- 39 22,4 

84 2 100 11 100 9 60 4 30,8 5 14,3 --- --- 31 35,2 

85 1 100 2 33,3 4 80 3 37,5 --- --- --- --- 10 29,4 

86 1 100 6 85,7 4 36,4 1 11,1 3 17,6 1 20 16 32 

87 2 66,7 1 100 8 80 2 16,7 1 3 --- --- 14 20,6 

88 4 100 23 100 27 90 15 48,4 5 11,1 --- --- 74 48,1 

89 --- --- 2 100 2 66,7 4 40 --- --- --- --- 8 17,4 

90 --- --- 5 100 8 80 2 15,4 2 5,4 --- --- 17 24,3 

91 1 100 2 50 2 40 3 21,4 2 11,1 --- --- 10 21,3 

92 5 100 32 97 41 95,3 43 89,6 22 59,5 3 13 146 77,2 

93 3 14,3 16 69,6 15 50 11 24,4 7 8 --- --- 52 21,8 

94 3 60 12 37,5 1 3,1 --- --- --- --- --- --- 16 11 

95 1 25 8 88,9 1 50 7 53,8 2 10,5 1 9,1 20 34,5 

96 --- --- 2 100 13 100 10 58,8 7 22,6 --- --- 32 45,7 

TOTAL 71 62,3 508 71,9 643 53,7 472 28,3 260 10,8 31 2,7 1985 27,5 



EuroNeoNet 


6.6.3 Surfactant within the First hour of Life Standardized Rate by Perinatal Risk Factors. 

Graph 6.6.3 corresponds to the 95% CI for the standardised surfactant within the first hour of life adjusted rate. 

Graph 6.6.3 

The results for Units 2, 6, 11, 13, 15, 16, 18, 20, 25, 36, 41, 42, 43, 44, 45, 47, 48, 52, 58, 61, 64, 65, 67, 70, 74, 75, 78, 81 and 94 

reached statistical significant relevance, being the surfactant within the first hour of life rate for these Units significantly 

smaller than the one expected according to the standard’s population surfactant within the first hour of life distribution. On 

the other hand, Units 23, 51, 55, 56, 68, 76, 79, 88, 92 and 96 had a bigger significant surfactant within the first hour of life rate 

than the one expected according to the standard’s population surfactant within the first hour of life distribution. 

Units 29, 31 and 37 didn’t register surfactant within the first hour of life. 





EuroNeoNet 


6.7 RDS Rate. 

Definition: RDS defined as: 

A: A PaO2 6.6 Kpa). 

AND 

B: A chest radiogram consistent with RDS (low lung volumes and reticulogranular appearance 

of lung fields, with or without air bronchograms). 

6.7.1 RDS Rate by Birth Weight. 

The global RDS rate for 2010 cohort has been of 65.1%, with a variation of 16% 

and 94.2% within units. 

RDS Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 1 100 7 87,5 12 80 10 47,6 12 38,7 9 47,4 51 53,7 

2 --- --- 1 100 2 66,7 2 40 2 28,6 2 22,2 9 36 

3 1 100 13 81,3 19 82,6 20 54,1 18 50 6 14,3 77 49,7 

4 3 100 7 87,5 8 100 14 87,5 4 19 7 50 43 61,4 

5 3 100 20 95,2 21 70 21 65,6 8 20,5 16 38,1 89 53,3 

6 6 66,7 12 75 22 64,7 12 44,4 16 36,4 12 28,6 80 46,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- 1 50 4 66,7 5 55,6 2 40 12 54,5 

9 1 100 --- --- 3 100 10 100 8 53,3 3 42,9 25 69,4 

10 1 100 7 100 6 85,7 12 75 7 50 8 50 41 67,2 

11 1 100 11 84,6 24 96 18 54,5 20 42,6 6 23,1 80 55,2 

12 3 100 55 98,2 76 93,8 89 89,9 104 67,1 71 81,6 398 82,7 

13 --- --- --- --- 5 100 2 100 7 58,3 4 80 18 72 

14 3 100 32 97 42 89,4 57 85,1 75 61 40 78,4 249 76,9 

15 1 100 6 100 22 100 7 100 25 69,4 9 81,8 70 84,3 

16 --- --- 2 100 4 100 2 50 10 52,6 6 54,5 24 60 

17 --- --- 9 100 13 92,9 19 73,1 14 50 10 76,9 65 72,2 

18 --- --- 4 100 5 71,4 16 69,6 16 72,7 7 53,8 48 69,6 

19 1 100 7 87,5 5 83,3 8 53,3 6 31,6 7 38,9 34 50,7 

20 --- --- 5 100 16 88,9 13 81,3 15 62,5 10 66,7 59 74,7 

21 --- --- 3 100 5 100 9 81,8 11 61,1 3 75 31 75,6 

22 1 100 5 100 10 90,9 10 83,3 7 36,8 9 56,3 42 65,6 

23 --- --- 2 50 9 69,2 9 69,2 15 75 24 88,9 59 76,6 

24 --- --- 26 100 57 100 45 91,8 35 85,4 --- --- 163 94,2 

25 --- --- --- --- 2 66,7 5 50 3 25 --- --- 10 40 

26 --- --- 17 94,4 14 100 8 57,1 15 68,2 --- --- 54 79,4 

27 --- --- 5 83,3 12 100 7 77,8 15 71,4 --- --- 39 81,3 

28 --- --- --- --- 5 62,5 --- --- --- --- --- --- 5 26,3 

29 1 100 1 100 2 66,7 1 33,3 5 55,6 --- --- 10 58,8 

30 --- --- 9 90 14 70 6 54,5 10 30,3 --- --- 39 52,7 

31 --- --- --- --- 1 33,3 1 50 --- --- --- --- 2 18,2 

32 2 100 5 83,3 3 42,9 6 75 1 11,1 --- --- 17 53,1 

33 2 50 17 94,4 17 54,8 13 38,2 11 21,2 --- --- 60 42,9 

34 1 100 5 83,3 12 100 7 70 2 15,4 --- --- 27 64,3 

35 1 100 --- --- 1 12,5 1 33,3 1 14,3 --- --- 4 16 

36 --- --- 8 100 10 83,3 11 61,1 12 38,7 --- --- 41 59,4 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

37 --- --- 3 100 2 66,7 7 63,6 9 42,9 1 100 22 56,4 

38 1 100 5 100 7 87,5 7 70 5 27,8 --- --- 25 59,5 

39 --- --- 4 80 11 61,1 5 41,7 3 13,6 1 50 24 40,7 

40 --- --- 4 100 4 80 8 100 3 23,1 1 100 20 64,5 

41 --- --- 10 90,9 11 91,7 11 73,3 12 57,1 1 100 45 75 

42 --- --- 1 50 6 100 13 72,2 2 25 --- --- 22 64,7 

43 --- --- 2 100 6 66,7 7 63,6 8 26,7 --- --- 23 44,2 

44 --- --- 6 100 5 55,6 --- --- 4 16 --- --- 15 28,8 

45 --- --- 5 100 3 42,9 5 41,7 2 12,5 --- --- 15 37,5 

46 1 100 2 100 --- --- 3 60 2 66,7 --- --- 8 72,7 

47 --- --- 3 100 2 50 4 66,7 5 33,3 --- --- 14 50 

48 --- --- 1 100 3 60 2 50 11 57,9 --- --- 17 58,6 

49 --- --- 3 100 4 80 6 60 2 50 --- --- 15 68,2 

50 --- --- 4 100 8 100 3 42,9 3 37,5 --- --- 18 66,7 

51 2 100 11 100 23 100 21 60 11 39,3 6 27,3 74 61,2 

52 2 66,7 16 84,2 30 71,4 15 40,5 20 40,8 --- --- 83 55,3 

53 --- --- 5 83,3 6 100 3 60 7 53,8 --- --- 21 70 

54 1 100 3 100 --- --- 1 50 4 57,1 --- --- 9 69,2 

55 --- --- 20 100 36 100 52 86,7 45 65,2 --- --- 153 82,7 

56 --- --- --- --- 4 100 1 16,7 1 14,3 --- --- 6 35,3 

57 --- --- 7 87,5 8 72,7 6 50 8 34,8 --- --- 29 53,7 

58 --- --- 4 100 5 38,5 6 33,3 5 19,2 --- --- 20 32,8 

59 --- --- 2 100 1 50 --- --- 1 14,3 --- --- 4 28,6 

60 --- --- 3 75 6 85,7 6 46,2 5 31,3 --- --- 20 50 

61 --- --- 6 66,7 8 88,9 8 57,1 6 46,2 --- --- 28 62,2 

62 1 100 6 85,7 3 50 4 44,4 --- --- --- --- 14 42,4 

63 --- --- 8 100 21 87,5 20 50 21 42,9 --- --- 70 57,9 

64 --- --- 1 100 1 20 6 50 5 21,7 --- --- 13 31,7 

65 --- --- 5 83,3 6 75 4 40 5 35,7 --- --- 20 52,6 

66 --- --- 5 100 24 96 17 81 7 41,2 --- --- 53 76,8 

67 --- --- 13 72,2 24 80 11 34,4 17 38,6 1 100 66 52,8 

68 --- --- 11 100 11 91,7 11 61,1 11 73,3 --- --- 44 78,6 

69 --- --- 3 100 1 100 1 16,7 3 25 --- --- 8 36,4 

70 --- --- 4 66,7 14 56 8 40 13 34,2 6 22,2 45 38,8 

71 --- --- 4 50 3 50 4 66,7 2 16,7 --- --- 13 40,6 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 1 100 3 100 5 100 8 61,5 1 33,3 --- --- 18 72 

74 2 100 17 100 22 91,7 18 78,3 22 84,6 28 96,6 109 90,1 

75 1 100 12 100 12 100 28 100 22 81,5 18 90 93 93 

76 3 75 21 100 27 96,4 23 76,7 25 75,8 19 63,3 118 80,8 

77 3 100 9 100 11 100 12 92,3 18 75 8 100 61 89,7 

78 --- --- 6 100 4 100 6 42,9 5 38,5 3 30 24 50 

79 1 100 11 100 8 100 13 76,5 21 80,8 16 88,9 70 86,4 

80 --- --- 3 100 10 90,9 4 66,7 11 68,8 2 66,7 30 76,9 

81 2 100 8 80 15 71,4 17 77,3 29 69 17 73,9 88 73,3 

82 1 100 5 100 10 90,9 12 100 12 63,2 11 73,3 51 81 

83 7 100 25 100 24 82,8 31 96,9 26 60,5 30 78,9 143 82,2 

84 3 100 9 100 18 100 14 87,5 28 66,7 --- --- 72 81,8 

85 1 100 3 75 8 100 5 100 9 69,2 --- --- 26 76,5 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

86 --- --- 5 100 17 94,4 3 50 14 93,3 4 66,7 43 86 

87 2 100 3 100 4 100 18 90 14 60,9 10 62,5 51 75 

88 2 100 26 96,3 26 100 30 85,7 19 48,7 16 61,5 119 76,8 

89 --- --- 2 100 3 100 10 76,9 10 83,3 15 93,8 40 87 

90 --- --- 4 100 9 100 9 81,8 13 52 14 63,6 49 69 

91 --- --- 5 100 5 100 7 77,8 12 75 11 91,7 40 85,1 

92 1 100 35 100 42 100 42 82,4 27 45,8 2 100 149 78,4 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 11 100 25 96,2 36 92,3 26 86,7 18 72 11 73,3 127 87 

95 1 100 10 100 9 75 4 57,1 8 47,1 9 81,8 41 70,7 

96 --- --- 2 100 14 82,4 10 76,9 5 22,7 7 43,8 38 54,3 

TOTAL 83 77,6 740 88,3 1126 82,4 1112 66,8 1152 48,4 539 57,3 4752 65,1 



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6.7.2 RDS Rate by Gestational Age. 

Table 6.7.2 shows the RDS distribution according to gestational age for each 

Unit. 

RDS Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 2 100 10 100 16 94,1 12 54,5 10 30,3 1 9,1 51 53,7 

2 --- --- 2 100 --- --- 3 75 4 28,6 --- --- 9 36 

3 5 100 14 100 16 84,2 22 66,7 18 25,7 2 14,3 77 49,7 

4 3 100 7 87,5 11 100 9 64,3 13 48,1 --- --- 43 61,4 

5 9 100 11 100 30 75 14 50 23 33,8 2 18,2 89 53,3 

6 3 37,5 17 89,5 22 75,9 23 59 15 24,2 --- --- 80 46,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 50 8 61,5 3 42,9 12 54,5 

9 1 100 2 100 6 100 8 88,9 7 53,8 1 20 25 69,4 

10 1 100 7 100 4 100 14 100 14 50 1 14,3 41 67,2 

11 --- --- 13 100 15 78,9 29 78,4 17 32,7 6 25 80 55,2 

12 1 100 36 97,3 66 98,5 111 95,7 135 76,7 49 58,3 398 82,7 

13 --- --- 1 100 2 100 5 71,4 8 88,9 2 33,3 18 72 

14 1 100 16 100 34 97,1 76 93,8 95 75,4 27 41,5 249 76,9 

15 --- --- 4 100 15 100 17 100 23 92 11 50 70 84,3 

16 1 100 1 100 3 75 4 100 11 61,1 4 33,3 24 60 

17 --- --- 3 100 16 100 21 91,3 24 77,4 1 5,9 65 72,2 

18 --- --- 4 100 10 90,9 15 93,8 15 57,7 4 33,3 48 69,6 

19 --- --- 7 87,5 3 75 13 81,3 10 35,7 1 9,1 34 50,7 

20 --- --- 8 100 16 94,1 8 80 23 74,2 4 30,8 59 74,7 

21 --- --- 3 100 5 100 5 83,3 18 85,7 --- --- 31 75,6 

22 --- --- 7 100 9 100 12 80 13 56,5 1 10 42 65,6 

23 --- --- 3 75 6 60 10 71,4 30 83,3 10 76,9 59 76,6 

24 1 100 15 100 49 100 56 93,3 42 87,5 --- --- 163 94,2 

25 --- --- --- --- 2 100 7 58,3 --- --- 1 14,3 10 40 

26 2 100 10 100 15 100 12 92,3 14 73,7 1 11,1 54 79,4 

27 --- --- 2 100 12 100 18 90 6 75 1 16,7 39 81,3 

28 --- --- --- --- 4 80 --- --- 1 16,7 --- --- 5 26,3 

29 --- --- 2 100 1 50 4 66,7 2 50 1 33,3 10 58,8 

30 2 100 11 91,7 12 75 6 60 5 27,8 3 18,8 39 52,7 

31 --- --- --- --- --- --- 1 50 1 33,3 --- --- 2 18,2 

32 1 100 5 71,4 5 71,4 4 57,1 1 20 1 20 17 53,1 

33 1 100 17 100 17 60,7 12 50 11 22 2 10 60 42,9 

34 --- --- 6 100 12 100 5 62,5 1 14,3 3 33,3 27 64,3 

35 --- --- --- --- --- --- 1 20 3 50 --- --- 4 16 

36 --- --- 8 100 8 100 10 62,5 15 78,9 --- --- 41 59,4 

37 --- --- 3 100 3 75 4 57,1 10 66,7 2 20 22 56,4 

38 --- --- 3 100 7 100 6 54,5 9 81,8 --- --- 25 59,5 

39 2 100 2 100 10 66,7 7 43,8 2 20 1 7,1 24 40,7 

40 1 100 --- --- 3 100 9 90 5 50 2 28,6 20 64,5 

41 --- --- 6 85,7 9 100 15 88,2 11 91,7 4 26,7 45 75 

42 --- --- 2 100 9 100 6 75 4 44,4 1 16,7 22 64,7 

43 --- --- 6 100 3 100 4 66,7 8 47,1 2 10 23 44,2 

44 --- --- 4 100 5 62,5 4 33,3 2 22,2 --- --- 15 28,8 

45 --- --- 3 100 3 100 8 47,1 --- --- 1 10 15 37,5 

46 1 100 --- --- 1 100 3 60 3 100 --- --- 8 72,7 



EuroNeoNet 


RDS Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

47 --- --- 2 100 4 80 5 71,4 3 37,5 --- --- 14 50 

48 --- --- --- --- 4 80 8 80 4 57,1 1 14,3 17 58,6 

49 --- --- 1 100 7 87,5 5 83,3 2 28,6 --- --- 15 68,2 

50 --- --- 4 100 6 100 5 71,4 3 42,9 --- --- 18 66,7 

51 3 75 15 100 17 94,4 20 71,4 18 46,2 1 5,9 74 61,2 

52 2 100 25 92,6 19 79,2 13 40,6 20 52,6 4 14,8 83 55,3 

53 --- --- 3 100 8 100 5 100 4 44,4 1 20 21 70 

54 --- --- 3 100 1 100 --- --- 3 60 2 50 9 69,2 

55 2 100 14 100 51 100 43 97,7 33 78,6 10 31,3 153 82,7 

56 --- --- 3 100 1 50 1 20 1 33,3 --- --- 6 35,3 

57 3 100 5 100 9 100 7 53,8 4 40 1 7,1 29 53,7 

58 1 100 4 80 6 75 5 45,5 4 20 --- --- 20 32,8 

59 --- --- 1 100 1 100 1 33,3 1 25 --- --- 4 28,6 

60 --- --- 4 100 5 100 2 25 9 60 --- --- 20 50 

61 --- --- 5 100 7 87,5 7 77,8 8 50 1 14,3 28 62,2 

62 --- --- 4 80 7 77,8 3 75 --- --- --- --- 14 42,4 

63 --- --- 7 100 22 91,7 20 80 17 48,6 4 13,3 70 57,9 

64 --- --- 1 100 2 28,6 6 66,7 4 33,3 --- --- 13 31,7 

65 --- --- 4 80 8 88,9 7 58,3 --- --- 1 12,5 20 52,6 

66 2 100 10 90,9 11 100 22 88 8 61,5 --- --- 53 76,8 

67 --- --- 14 77,8 21 91,3 23 57,5 8 29,6 --- --- 66 52,8 

68 1 100 5 100 16 94,1 11 78,6 10 71,4 1 20 44 78,6 

69 1 100 --- --- 4 100 1 33,3 2 50 --- --- 8 36,4 

70 --- --- 9 75 10 58,8 13 56,5 12 27,3 1 5 45 38,8 

71 --- --- 5 71,4 3 50 3 75 2 25 --- --- 13 40,6 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- 2 100 5 83,3 7 87,5 4 57,1 --- --- 18 72 

74 --- --- 12 92,3 24 100 31 88,6 42 85,7 --- --- 109 90,1 

75 --- --- 12 100 13 100 22 100 35 92,1 11 73,3 93 93 

76 --- --- 18 94,7 24 100 25 96,2 42 75 9 42,9 118 80,8 

77 --- --- 11 100 9 100 20 100 18 90 3 37,5 61 89,7 

78 --- --- 1 50 6 100 9 56,3 8 42,1 --- --- 24 50 

79 --- --- 8 100 11 100 19 95 27 90 5 41,7 70 86,4 

80 --- --- 1 100 10 100 7 100 7 77,8 5 41,7 30 76,9 

81 --- --- 7 87,5 16 88,9 26 86,7 33 73,3 6 31,6 88 73,3 

82 --- --- 7 100 11 100 14 93,3 18 69,2 1 25 51 81 

83 9 100 12 100 33 97,1 37 88,1 48 72,7 4 36,4 143 82,2 

84 2 100 11 100 15 100 12 92,3 30 85,7 2 16,7 72 81,8 

85 1 100 5 83,3 5 100 8 100 7 58,3 --- --- 26 76,5 

86 1 100 7 100 11 100 8 88,9 14 82,4 2 40 43 86 

87 3 100 1 100 10 100 11 91,7 21 63,6 5 55,6 51 75 

88 4 100 23 100 30 100 30 96,8 27 58,7 5 23,8 119 76,8 

89 --- --- 2 100 3 100 10 100 22 95,7 3 37,5 40 87 

90 --- --- 5 100 11 100 9 69,2 23 62,2 1 20 49 69 

91 1 100 4 100 5 100 14 100 13 72,2 3 60 40 85,1 

92 5 100 33 100 43 97,7 40 83,3 22 59,5 6 26,1 149 78,4 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 5 100 32 100 30 93,8 31 88,6 22 71 7 63,6 127 87 

95 4 100 9 100 2 100 10 76,9 13 68,4 3 27,3 41 70,7 

96 --- --- 2 100 11 84,6 12 70,6 12 38,7 1 14,3 38 54,3 

TOTAL 88 76,5 654 91,7 1083 88 1283 76,2 1378 56,9 266 23,5 4752 65,1 



EuroNeoNet 


6.7.3 RDS Standardized Rate by Perinatal Risk Factors. 

Graph 6.7.3, corresponds to the 95% CI for the standardised RDS adjusted rate. 

Graph 6.7.3 

The results for Units 2, 6, 23, 28, 31, 33, 35, 39, 44, 45, 58, 59, 64, 69 and 70 reached statistical significant relevance, being 

the RDS rate for these Units significantly smaller than the one expected according to the standard’s population RDS 

distribution. On the other hand, Units 12, 14, 15, 24, 55, 74, 75, 76, 77, 79, 83, 84 and 94 had a bigger significant RDS rate 

than the one expected according to the standard’s population RDS distribution. 

Unit 93 didn’t register RDS. 





EuroNeoNet 


6.8 Early Sepsis Rate. 

Definition: if a bacterial pathogen from the list in Appendix I (ENS Manual) was recovered from 

a blood and/or cerebrospinal fluid culture obtained before day 3 of life. 

6.8.1 Early Sepsis Rate by Birth Weight. 

The global Early sepsis rate for 2010 cohort has been of 3.4%, with a variation 

of 0.7% and 20.5% within units. 

Early Bacterial Sepsis Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- --- --- 1 6,7 2 9,5 1 3,2 1 5,3 5 5,3 

2 --- --- --- --- --- --- --- --- --- --- 1 11,1 1 4 

3 --- --- --- --- 3 13 2 5,4 --- --- 1 2,4 6 3,9 

4 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,4 

5 1 33,3 2 9,5 1 3,3 --- --- --- --- --- --- 4 2,4 

6 --- --- --- --- 1 2,9 --- --- --- --- 1 2,4 2 1,2 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

11 --- --- --- --- --- --- --- --- --- --- 1 3,8 1 0,7 

12 --- --- 3 5,4 1 1,2 --- --- 3 1,9 1 1,1 8 1,7 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- --- --- 2 4,3 1 1,5 1 0,8 1 2 5 1,5 

15 --- --- 1 16,7 5 22,7 --- --- 4 11,1 1 9,1 11 13,3 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- --- --- 1 3,6 --- --- 1 1,1 

18 --- --- --- --- 1 14,3 6 26,1 --- --- 1 7,7 8 11,6 

19 --- --- 1 12,5 --- --- --- --- 1 5,3 --- --- 2 3 

20 --- --- --- --- 1 5,6 --- --- --- --- --- --- 1 1,3 

21 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 4,9 

22 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 1,6 

23 --- --- 10 32,3 6 11,8 11 19,3 5 10,4 --- --- 32 14,9 

24 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- 1 16,7 2 16,7 --- --- --- --- --- --- 3 6,3 

28 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 1 10 --- --- --- --- --- --- --- --- 1 1,4 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- 1 16,7 1 14,3 --- --- --- --- --- --- 2 6,3 

33 --- --- 1 5,6 --- --- 1 2,9 --- --- --- --- 2 1,4 

34 --- --- --- --- 2 16,7 --- --- --- --- --- --- 2 4,8 

35 --- --- 1 16,7 1 12,5 --- --- --- --- --- --- 2 8 

36 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 1,4 

37 --- --- 1 33,3 --- --- 1 9,1 2 9,5 --- --- 4 10,3 

38 --- --- --- --- --- --- 1 10 --- --- --- --- 1 2,4 

39 --- --- --- --- 2 11,1 1 8,3 --- --- --- --- 3 5,1 

40 --- --- --- --- --- --- 2 25 1 7,7 1 100 4 12,9 

41 --- --- --- --- 1 8,3 1 6,7 --- --- --- --- 2 3,3 

42 --- --- --- --- 1 16,7 2 11,1 1 12,5 --- --- 4 11,8 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

43 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

44 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,9 

45 --- --- --- --- --- --- 3 25 --- --- --- --- 3 7,5 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 3,6 

48 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 3,4 

49 --- --- --- --- 1 20 1 10 --- --- --- --- 2 9,1 

50 --- --- 1 25 --- --- --- --- --- --- --- --- 1 3,7 

51 --- --- --- --- 1 4,3 --- --- --- --- --- --- 1 0,8 

52 --- --- --- --- --- --- 1 2,7 --- --- --- --- 1 0,7 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 4 20 6 17,1 5 8,5 1 1,4 --- --- 16 8,7 

56 --- --- --- --- --- --- --- --- 2 28,6 --- --- 2 11,8 

57 --- --- --- --- --- --- --- --- 1 4,3 --- --- 1 1,9 

58 --- --- --- --- 1 7,7 --- --- 1 3,8 --- --- 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- 2 15,4 1 6,3 --- --- 3 7,7 

61 --- --- 1 11,1 --- --- --- --- 1 7,7 --- --- 2 4,4 

62 --- --- 1 14,3 1 16,7 1 11,1 --- --- --- --- 3 9,1 

63 --- --- --- --- --- --- 3 7,5 1 2 --- --- 4 3,3 

64 --- --- --- --- --- --- 1 8,3 --- --- --- --- 1 2,4 

65 --- --- --- --- --- --- 1 10 1 7,1 --- --- 2 5,3 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- --- --- 3 10 4 12,5 1 2,3 1 100 9 7,2 

68 --- --- --- --- --- --- 1 5,6 --- --- --- --- 1 1,8 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- --- --- 1 4 --- --- --- --- --- --- 1 0,9 

71 --- --- --- --- --- --- --- --- 1 8,3 --- --- 1 3,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- 3 23,1 --- --- --- --- 3 12 

74 --- --- 1 5,9 --- --- --- --- 1 3,8 3 10,3 5 4,1 

75 --- --- 1 8,3 --- --- --- --- 2 7,4 2 10 5 5 

76 --- --- --- --- 1 3,6 --- --- --- --- 2 6,7 3 2,1 

77 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- 1 3,8 --- --- 1 1,2 

80 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 2,6 

81 --- --- --- --- --- --- 1 4,5 1 2,4 --- --- 2 1,7 

82 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

83 1 14,3 2 8 --- --- --- --- 2 4,7 1 2,6 6 3,4 

84 1 33,3 7 77,8 3 16,7 4 25 3 7,1 --- --- 18 20,5 

85 --- --- --- --- 3 37,5 --- --- 1 7,7 --- --- 4 11,8 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

86 --- --- 1 20 4 22,2 --- --- --- --- 1 16,7 6 12 

87 --- --- 1 33,3 1 25 --- --- --- --- --- --- 2 2,9 

88 --- --- 1 3,8 2 7,7 --- --- --- --- --- --- 3 1,9 

89 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,2 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- --- --- --- --- 1 5,9 1 3,4 --- --- 2 2,4 

93 --- --- 1 2,8 --- --- 1 2,1 --- --- --- --- 2 0,8 

94 1 9,1 --- --- --- --- 1 3,3 --- --- --- --- 2 1,4 

96 --- --- --- --- --- --- --- --- --- --- 1 6,3 1 1,4 

TOTAL 4 3,8 48 5,8 64 4,7 65 3,9 46 1,9 21 2,3 248 3,4 



EuroNeoNet 


6.8.2 Early Sepsis Rate by Gestational Age. 

Table 6.8.2 shows the Early Bacterial Sepsis distribution according to 


Unit 

Code 

Early Bacterial Sepsis Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- --- --- 2 11,8 2 9,1 1 3 --- --- 5 5,3 

2 --- --- --- --- --- --- --- --- 1 7,1 --- --- 1 4 

3 --- --- 2 14,3 --- --- 4 12,1 --- --- --- --- 6 3,9 

4 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,4 

5 1 11,1 1 9,1 2 5 --- --- --- --- --- --- 4 2,4 

6 --- --- 1 5,3 --- --- --- --- 1 1,6 --- --- 2 1,2 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

11 --- --- --- --- --- --- --- --- 1 1,9 --- --- 1 0,7 

12 --- --- 4 10,8 --- --- 1 0,9 3 1,7 --- --- 8 1,7 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- --- --- 2 5,7 1 1,2 2 1,6 --- --- 5 1,5 

15 --- --- 2 50 4 26,7 3 17,6 2 8 --- --- 11 13,3 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- 1 4,3 --- --- --- --- 1 1,1 

18 --- --- 1 25 3 27,3 2 12,5 2 7,7 --- --- 8 11,6 

19 --- --- 1 12,5 --- --- --- --- 1 3,6 --- --- 2 3 

20 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,3 

21 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 4,9 

22 --- --- --- --- --- --- --- --- 1 4,3 --- --- 1 1,6 

23 --- --- 11 37,9 11 27,5 9 14,5 1 1,5 --- --- 32 14,9 

24 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- 1 50 2 16,7 --- --- --- --- --- --- 3 6,3 

28 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 1 8,3 --- --- --- --- --- --- --- --- 1 1,4 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 100 --- --- 1 14,3 --- --- --- --- --- --- 2 6,3 

33 --- --- 1 5,9 --- --- --- --- 1 2 --- --- 2 1,4 

34 --- --- --- --- 2 16,7 --- --- --- --- --- --- 2 4,8 

35 --- --- --- --- 2 28,6 --- --- --- --- --- --- 2 8 

36 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 1,4 

37 --- --- 1 33,3 --- --- 1 14,3 1 6,7 1 10 4 10,3 

38 --- --- --- --- 1 14,3 --- --- --- --- --- --- 1 2,4 

39 --- --- --- --- 2 13,3 1 6,3 --- --- --- --- 3 5,1 

40 --- --- --- --- --- --- 2 20 2 20 --- --- 4 12,9 

41 --- --- --- --- 1 11,1 --- --- 1 8,3 --- --- 2 3,3 

42 --- --- 1 50 1 11,1 2 25 --- --- --- --- 4 11,8 

43 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

44 --- --- 1 25 --- --- --- --- --- --- --- --- 1 1,9 

45 --- --- --- --- --- --- 3 17,6 --- --- --- --- 3 7,5 



EuroNeoNet 


Unit 

Code 

Early Bacterial Sepsis Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- 1 12,5 --- --- 1 3,6 

48 --- --- --- --- --- --- 1 10 --- --- --- --- 1 3,4 

49 --- --- --- --- 1 12,5 1 16,7 --- --- --- --- 2 9,1 

50 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,7 

51 --- --- 1 6,7 --- --- --- --- --- --- --- --- 1 0,8 

52 --- --- --- --- --- --- 1 3,1 --- --- --- --- 1 0,7 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 4 28,6 7 13,7 5 11,6 --- --- --- --- 16 8,7 

56 --- --- --- --- --- --- --- --- 1 33,3 1 25 2 11,8 

57 --- --- --- --- --- --- --- --- 1 10 --- --- 1 1,9 

58 --- --- --- --- --- --- 1 9,1 --- --- 1 6,3 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- 2 25 1 6,7 --- --- 3 7,7 

61 --- --- --- --- 1 12,5 1 11,1 --- --- --- --- 2 4,4 

62 --- --- 1 20 --- --- 2 50 --- --- --- --- 3 9,1 

63 --- --- --- --- 2 8,3 1 4 1 2,9 --- --- 4 3,3 

64 --- --- --- --- --- --- --- --- --- --- 1 8,3 1 2,4 

65 --- --- --- --- --- --- 1 8,3 --- --- 1 12,5 2 5,3 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- 2 11,1 2 8,7 3 7,5 2 7,4 --- --- 9 7,2 

68 --- --- --- --- 1 5,9 --- --- --- --- --- --- 1 1,8 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 8,3 --- --- --- --- --- --- --- --- 1 0,9 

71 --- --- --- --- --- --- --- --- --- --- 1 14,3 1 3,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- 1 12,5 2 28,6 --- --- 3 12 

74 --- --- 1 7,7 --- --- --- --- 4 8,2 --- --- 5 4,1 

75 --- --- 1 8,3 --- --- 2 9,1 2 5,3 --- --- 5 5 

76 --- --- --- --- 1 4,2 --- --- 2 3,6 --- --- 3 2,1 

77 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- 1 3,3 --- --- 1 1,2 

80 --- --- --- --- 1 10 --- --- --- --- --- --- 1 2,6 

81 --- --- --- --- 1 5,6 1 3,3 --- --- --- --- 2 1,7 

82 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

83 3 33,3 --- --- --- --- 2 4,8 1 1,5 --- --- 6 3,4 

84 2 100 8 72,7 3 20 1 7,7 3 8,6 1 8,3 18 20,5 

85 --- --- 1 16,7 2 40 --- --- 1 8,3 --- --- 4 11,8 

86 --- --- 2 28,6 3 27,3 --- --- 1 5,9 --- --- 6 12 

87 --- --- 1 100 1 10 --- --- --- --- --- --- 2 2,9 

88 1 25 1 4,3 1 3,4 --- --- --- --- --- --- 3 1,9 

89 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,2 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- --- --- 1 4,2 1 7,7 --- --- --- --- 2 2,4 

93 1 4,8 --- --- 1 3,3 --- --- --- --- --- --- 2 0,8 

94 --- --- 1 3,1 --- --- --- --- --- --- 1 9,1 2 1,4 

96 --- --- --- --- --- --- --- --- 1 3,2 --- --- 1 1,4 

TOTAL 9 8,3 58 8,1 68 5,5 59 3,5 46 1,9 8 0,7 248 3,4 



EuroNeoNet 


6.8.3 Early Sepsis Standardized Rate by Perinatal Risk Factors. 

Graph 6.8.3, corresponds to the 95% CI for the standardised early bacterial sepsis adjusted rate. 

Graph 6.8.3 

The results for Units 6, 11, 12, 14, 17, 20, 33, 51, 52, 70, 79, 81, 92, 93 and 94 reached statistical significant relevance, being 

the early bacterial sepsis rate for these Units significantly smaller than the one expected according to the standard’s 

population early bacterial sepsis distribution. On the other hand, Units 15, 23, 55 and 84 had a bigger significant early 

bacterial sepsis rate than the one expected according to the standard’s population early bacterial sepsis distribution. 

Units 8, 9, 10, 13, 16, 24, 25, 26, 28, 29, 31, 43, 46, 53, 54, 59, 66, 69, 77, 78, 82, 90 and 91 didn’t register early bacterial sepsis. 





EuroNeoNet 


6.9 Pneumothorax Rate. 

Definition: if the infant had extrapleural air diagnosed by chest radiograph or needle aspiration 

(thoracentesis). 

For infants who had thoracic surgery and a chest tube was placed at the time of surgery OR if 

free air was only present on a Chest Radiograph taken immediately after thoracic surgery and 

was not treated with a chest tube, check NO. 

For infants who had thoracic surgery and then later developed extrapleural air diagnosed by 

Chest Radiograph or needle thoracentesis, check YES. 

6.9.1 Pneumothorax Rate by Birth Weight. 

Table 6.9.1 shows the Pneumothorax distribution according to birth weight 

groups for each Unit. 

The global pneumothorax rate for 2010 cohort has been of 3.6%, with a 


Unit 

Code 

NTX Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- --- --- --- --- --- --- 1 3,2 1 5,3 2 2,1 

2 --- --- 1 100 --- --- --- --- --- --- 1 11,1 2 8 

3 --- --- --- --- 3 13 --- --- 2 5,6 --- --- 5 3,2 

4 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 1,4 

5 --- --- --- --- 1 3,3 --- --- 3 7,7 3 7,1 7 4,2 

6 --- --- --- --- --- --- --- --- --- --- 1 2,4 1 0,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- --- --- 1 14,3 --- --- 3 21,4 2 12,5 6 9,8 

11 --- --- --- --- 1 4 --- --- 1 2,1 --- --- 2 1,4 

12 1 33,3 7 12,5 6 7,4 4 4 4 2,6 4 4,6 26 5,4 

13 --- --- --- --- 1 20 --- --- --- --- --- --- 1 4 

14 --- --- --- --- 2 4,3 3 4,5 6 4,9 2 3,9 13 4 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- 1 3,8 --- --- 1 7,7 2 2,2 

18 --- --- --- --- --- --- 1 4,3 --- --- --- --- 1 1,4 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- --- --- 1 5,6 --- --- 2 8,3 --- --- 3 3,8 

21 --- --- --- --- --- --- --- --- --- --- 1 25 1 2,4 

22 --- --- 1 20 --- --- --- --- --- --- --- --- 1 1,6 

23 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

24 --- --- --- --- 2 3,5 --- --- --- --- --- --- 2 1,2 

25 --- --- --- --- --- --- 1 10 --- --- --- --- 1 4 

26 --- --- 1 5,3 2 14,3 --- --- 1 4,5 --- --- 4 5,8 

27 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 2,1 

28 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 5,3 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- --- --- 3 15 --- --- 1 3 --- --- 4 5,4 

31 --- --- --- --- --- --- --- --- 1 16,7 --- --- 1 9,1 

32 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

33 --- --- 2 11,1 --- --- --- --- 1 1,9 --- --- 3 2,1 

34 --- --- 2 33,3 1 8,3 --- --- --- --- --- --- 3 7,1 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- 1 12,5 --- --- 1 5,6 2 6,5 --- --- 4 5,8 

37 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 2,6 

38 1 100 --- --- --- --- --- --- --- --- --- --- 1 2,4 

39 --- --- --- --- 2 11,1 --- --- --- --- --- --- 2 3,4 

40 --- --- 1 25 --- --- 1 12,5 --- --- --- --- 2 6,5 

41 --- --- --- --- 1 8,3 --- --- --- --- 1 100 2 3,4 

42 --- --- 1 50 --- --- 1 5,6 --- --- --- --- 2 5,9 

43 --- --- --- --- 1 11,1 --- --- 1 3,3 --- --- 2 3,8 

44 --- --- --- --- --- --- --- --- 2 8 --- --- 2 3,8 

45 --- --- --- --- --- --- --- --- 1 6,3 --- --- 1 2,5 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- 1 20 --- --- 1 5,3 --- --- 2 6,9 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- --- --- 1 12,5 --- --- 1 3,7 

51 1 50 1 9,1 6 26,1 2 5,7 5 17,9 --- --- 15 12,4 

52 --- --- 1 5,3 2 4,8 1 2,7 --- --- --- --- 4 2,7 

53 --- --- 1 16,7 --- --- --- --- 1 7,7 --- --- 2 6,7 

54 1 100 1 33,3 --- --- --- --- --- --- --- --- 2 15,4 

55 --- --- --- --- 2 5,6 --- --- 1 1,4 --- --- 3 1,6 

56 --- --- --- --- 1 25 --- --- --- --- --- --- 1 5,9 

57 --- --- 1 12,5 --- --- 2 16,7 --- --- --- --- 3 5,6 

58 --- --- --- --- --- --- 1 5,6 1 3,8 --- --- 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- --- --- 4 25 --- --- 4 10 

61 --- --- 2 22,2 --- --- --- --- 1 7,7 --- --- 3 6,7 

62 --- --- 2 28,6 1 16,7 1 11,1 --- --- --- --- 4 12,1 

63 --- --- 1 12,5 2 8,3 1 2,5 --- --- --- --- 4 3,3 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

66 --- --- 1 20 2 8 1 4,8 --- --- --- --- 4 5,8 

67 --- --- 5 27,8 8 26,7 2 6,3 3 6,8 --- --- 18 14,4 

68 --- --- 1 9,1 --- --- --- --- --- --- --- --- 1 1,8 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 16,7 --- --- 1 5 1 2,6 3 11,1 6 5,2 

71 --- --- 1 12,5 --- --- 1 16,7 --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 8 

74 --- --- 3 17,6 3 12,5 2 8,7 2 7,7 --- --- 10 8,3 

75 --- --- 1 8,3 1 8,3 2 7,1 2 7,4 --- --- 6 6 

76 --- --- 1 4,8 --- --- 2 6,7 1 3 1 3,3 5 3,4 

77 --- --- 1 11,1 1 9,1 1 7,7 --- --- --- --- 3 4,4 

78 --- --- --- --- --- --- --- --- 1 7,7 --- --- 1 2,1 

79 --- --- --- --- --- --- 1 5,9 --- --- 1 5,6 2 2,5 

80 --- --- --- --- 1 9,1 --- --- 1 6,3 --- --- 2 5,1 

81 --- --- --- --- 1 4,8 --- --- --- --- 1 4,3 2 1,7 

82 1 100 --- --- --- --- 2 16,7 1 5,3 --- --- 4 6,3 

83 --- --- 2 8 1 3,4 --- --- 1 2,3 2 5,3 6 3,4 

84 --- --- --- --- --- --- 1 6,3 1 2,4 --- --- 2 2,3 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- 1 20 1 5,6 --- --- 1 6,7 --- --- 3 6 

87 --- --- --- --- --- --- 1 5 --- --- --- --- 1 1,5 

88 --- --- --- --- 3 11,5 3 8,6 3 7,7 2 7,7 11 7,1 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- 2 22,2 --- --- --- --- --- --- 2 2,8 

91 --- --- --- --- --- --- 1 11,1 --- --- 3 25 4 8,5 

92 --- --- 1 2,9 1 2,4 1 2 2 3,4 --- --- 5 2,6 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 --- --- --- --- 1 2,6 1 3,3 1 4 --- --- 3 2,1 

95 --- --- --- --- --- --- --- --- 1 5,9 --- --- 1 1,7 

96 --- --- --- --- --- --- --- --- 1 4,5 --- --- 1 1,4 

TOTAL 5 4,6 49 5,7 70 5 44 2,6 72 3 30 3,2 270 3,6 



EuroNeoNet 


6.9.2 Pneumothorax Rate by Gestational Age. 

Table 6.9.2 shows the Pneumothorax distribution according to gestational age 

for each Unit. 

Unit 

Code 

NTX Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- --- --- --- --- 1 4,5 1 3 --- --- 2 2,1 

2 --- --- 1 50 --- --- --- --- 1 7,1 --- --- 2 8 

3 --- --- 3 21,4 --- --- 1 3 1 1,4 --- --- 5 3,2 

4 --- --- --- --- --- --- --- --- 1 3,7 --- --- 1 1,4 

5 --- --- --- --- --- --- 3 10,7 3 4,4 1 9,1 7 4,2 

6 --- --- --- --- --- --- --- --- 1 1,6 --- --- 1 0,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- --- --- --- --- 2 14,3 4 14,3 --- --- 6 9,8 

11 --- --- --- --- --- --- 1 2,7 1 1,9 --- --- 2 1,4 

12 1 100 4 10,8 7 10,4 9 7,8 4 2,3 1 1,2 26 5,4 

13 --- --- 1 100 --- --- --- --- --- --- --- --- 1 4 

14 --- --- 2 12,5 --- --- 3 3,7 7 5,6 1 1,5 13 4 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- 1 4,3 1 3,2 --- --- 2 2,2 

18 --- --- --- --- --- --- 1 6,3 --- --- --- --- 1 1,4 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- --- --- 1 5,9 1 10 1 3,2 --- --- 3 3,8 

21 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 2,4 

22 --- --- 1 14,3 --- --- --- --- --- --- --- --- 1 1,6 

23 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

24 --- --- --- --- 2 4,1 --- --- --- --- --- --- 2 1,2 

25 --- --- --- --- 1 50 --- --- --- --- --- --- 1 4 

26 --- --- 1 10 2 13,3 --- --- 1 5,3 --- --- 4 5,8 

27 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 2,1 

28 --- --- --- --- 1 20 --- --- --- --- --- --- 1 5,3 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 1 50 2 16,7 --- --- --- --- 1 5,6 --- --- 4 5,4 

31 --- --- --- --- --- --- --- --- --- --- 1 20 1 9,1 

32 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

33 --- --- 2 11,8 --- --- --- --- 1 2 --- --- 3 2,1 

34 --- --- 1 16,7 2 16,7 --- --- --- --- --- --- 3 7,1 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- 1 12,5 --- --- --- --- 3 15,8 --- --- 4 5,8 

37 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 2,6 

38 --- --- --- --- 1 14,3 --- --- --- --- --- --- 1 2,4 

39 --- --- --- --- 1 6,7 --- --- 1 10 --- --- 2 3,4 

40 --- --- --- --- 1 33,3 1 10 --- --- --- --- 2 6,5 

41 --- --- --- --- --- --- 2 11,8 --- --- --- --- 2 3,4 

42 --- --- --- --- 1 11,1 1 12,5 --- --- --- --- 2 5,9 

43 --- --- 1 16,7 --- --- --- --- 1 5,9 --- --- 2 3,8 

44 --- --- --- --- --- --- --- --- 2 22,2 --- --- 2 3,8 

45 --- --- --- --- --- --- 1 5,9 --- --- --- --- 1 2,5 



EuroNeoNet 


Unit 

Code 

NTX Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- 2 20 --- --- --- --- 2 6,9 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- 1 14,3 --- --- --- --- 1 3,7 

51 --- --- 6 40 3 16,7 1 3,6 3 7,7 2 11,8 15 12,4 

52 --- --- 2 7,4 1 4,2 1 3,1 --- --- --- --- 4 2,7 

53 --- --- 1 33,3 --- --- --- --- --- --- 1 20 2 6,7 

54 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 15,4 

55 --- --- --- --- --- --- 2 4,5 --- --- 1 3,1 3 1,6 

56 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 5,9 

57 1 33,3 --- --- 1 11,1 1 7,7 --- --- --- --- 3 5,6 

58 --- --- --- --- --- --- --- --- 2 10 --- --- 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- 1 12,5 3 20 --- --- 4 10 

61 --- --- 2 40 --- --- --- --- 1 6,3 --- --- 3 6,7 

62 --- --- 1 20 2 22,2 1 25 --- --- --- --- 4 12,1 

63 --- --- 1 14,3 3 12,5 --- --- --- --- --- --- 4 3,3 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

66 1 50 1 9,1 1 9,1 1 4 --- --- --- --- 4 5,8 

67 --- --- 7 38,9 4 17,4 5 12,5 2 7,4 --- --- 18 14,4 

68 --- --- 1 20 --- --- --- --- --- --- --- --- 1 1,8 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 8,3 --- --- 1 4,3 4 9,1 --- --- 6 5,2 

71 --- --- 1 14,3 --- --- 1 25 --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 1 50 --- --- 1 12,5 --- --- --- --- 2 8 

74 --- --- 4 30,8 1 4,2 4 11,4 1 2 --- --- 10 8,3 

75 --- --- --- --- 3 23,1 --- --- 3 7,9 --- --- 6 6 

76 --- --- 1 5,3 1 4,2 1 3,8 2 3,6 --- --- 5 3,4 

77 --- --- 2 18,2 --- --- 1 5 --- --- --- --- 3 4,4 

78 --- --- --- --- --- --- 1 6,3 --- --- --- --- 1 2,1 

79 --- --- --- --- --- --- 1 5 1 3,3 --- --- 2 2,5 

80 --- --- --- --- 1 10 --- --- --- --- 1 8,3 2 5,1 

81 --- --- --- --- --- --- 1 3,3 1 2,2 --- --- 2 1,7 

82 --- --- --- --- 2 18,2 2 13,3 --- --- --- --- 4 6,3 

83 1 11,1 1 8,3 1 2,9 --- --- 3 4,5 --- --- 6 3,4 

84 --- --- --- --- --- --- --- --- 2 5,7 --- --- 2 2,3 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- 1 14,3 1 9,1 --- --- 1 5,9 --- --- 3 6 

87 --- --- --- --- 1 10 --- --- --- --- --- --- 1 1,5 

88 --- --- 2 8,7 2 6,7 3 9,7 3 6,5 1 4,8 11 7,1 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- 1 20 1 9,1 --- --- --- --- --- --- 2 2,8 

91 --- --- --- --- 1 20 1 7,1 2 11,1 --- --- 4 8,5 

92 1 20 1 3 1 2,3 1 2,1 1 2,7 --- --- 5 2,6 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 --- --- 1 3,1 --- --- 1 2,9 1 3,2 --- --- 3 2,1 

95 --- --- --- --- --- --- --- --- --- --- 1 9,1 1 1,7 

96 --- --- --- --- --- --- --- --- 1 3,2 --- --- 1 1,4 

TOTAL 6 5,2 62 8,4 52 4,1 64 3,7 75 3,1 11 1 270 3,6 



EuroNeoNet 


6.9.3 Pneumothorax Standardized Rate by Perintal Risk Factors. 

Graph 6.9.3, corresponds to the 95% CI for the standardised pneumothorax adjusted rate. 

Graph 6.9.3 

The results for Units 6, 11, 24, 55, 81, 92, 95 and 96 reached statistical significant relevance, being the pneumothorax rate 

for these Units significantly smaller than the one expected according to the standard’s population pneumothorax 

distribution. On the other hand, Units 51 and 67 had a bigger significant pneumothorax rate than the one expected 

according to the standard’s population pneumothorax distribution. 

Units 8, 9, 15, 16, 19, 23, 29, 32, 35, 46, 47, 49, 59, 64, 65, 69, 85, 89 and 93 didn’t register pneumothorax. 

Note 1: Standardization items: Birth weight Z-Score by gestational age, gender, 1-min Apgar 

Score, 5-min apgar Score and multiple gestation. 




EuroNeoNet 


6.10 PIVH (Grades III or IV) Rate. 

Definition: If a cranial imaging was performed, enter grade based on criteria below: 

Grade 0 - No subependymal or intraventricular hemorrhage. 

Grade 1 – Subependymal germinal matrix hemorrhage only. 

Grade 2 – Intraventricular blood, no ventricular dilation. 

Grade 3 - Intraventricular blood, ventricular dilation. 

Grade 4 – Intraparenchymal hemorrhage. 

If multiple ultrasounds were done on or before day 28 record the most severe grade. 

Value calculated only for babies with a cranial imaging done, and grades recorded. 

6.10.1 PIVH (Grades III or IV) Rate by Birth Weight. 

The global PIVH (Grades III or IV) rate for 2010 cohort has been of 7.8%, with a 


PIVH (Grades III or IV) Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- 1 12,5 1 6,7 2 12,5 --- --- --- --- 4 5,5 

2 --- --- --- --- 1 33,3 1 25 1 20 --- --- 3 20 

3 1 100 4 26,7 3 13,6 2 8 --- --- --- --- 10 7,8 

4 1 50 2 28,6 --- --- 1 6,7 --- --- --- --- 4 8 

5 --- --- 3 16,7 1 3,8 1 4,2 1 4,8 1 3,6 7 5,8 

6 1 20 4 26,7 4 13,3 --- --- --- --- 1 2,9 10 6,9 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 16,7 1 16,7 1 20 3 15,8 

9 --- --- --- --- --- --- 1 11,1 1 6,7 --- --- 2 6,1 

10 --- --- --- --- 1 14,3 --- --- --- --- --- --- 1 1,8 

11 --- --- 3 23,1 1 4 3 9,4 2 4,5 2 7,7 11 7,8 

12 2 66,7 16 32 10 13,9 4 4,3 9 6,6 6 7,7 47 10,9 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- 5 17,2 4 8,9 4 6,2 4 3,4 --- --- 17 5,6 

15 --- --- --- --- 1 5,9 --- --- --- --- --- --- 1 1,4 

16 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,8 

17 --- --- 1 12,5 1 7,1 1 4,3 --- --- --- --- 3 3,5 

18 --- --- 1 25 --- --- 1 5 1 4,8 1 8,3 4 6,3 

19 --- --- 2 25 --- --- --- --- --- --- --- --- 2 3,1 

20 --- --- 1 20 1 5,6 --- --- 1 4,2 --- --- 3 3,8 

21 --- --- --- --- 2 50 1 9,1 --- --- --- --- 3 7,5 

22 --- --- --- --- 1 9,1 --- --- 1 5,3 --- --- 2 3,1 

23 --- --- 2 25 7 38,9 4 22,2 2 20 --- --- 15 24,6 

24 --- --- 5 19,2 6 10,5 4 8,3 1 2,6 --- --- 16 9,4 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- 2 11,8 1 7,1 1 7,7 --- --- --- --- 4 6,1 

27 --- --- 1 16,7 2 20 1 14,3 3 16,7 --- --- 7 17,1 

28 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 5,6 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 2 20 6 33,3 1 10 1 3,1 --- --- 10 14,3 


Note: Excluded babies died in Delivery Room and babies without cranial imaging done.Analyzed population: Admitted 

babies with a cranial imaging done.

EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 50 1 16,7 2 28,6 --- --- --- --- --- --- 4 12,5 

33 --- --- 1 6,3 3 10 1 3,1 1 2,2 --- --- 6 4,7 

34 --- --- --- --- 3 25 --- --- --- --- --- --- 3 7,1 

35 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 4 

36 --- --- 1 12,5 2 18,2 1 5,9 1 3,2 --- --- 5 7,5 

37 --- --- 1 33,3 --- --- 1 11,1 1 6,3 --- --- 3 9,4 

38 --- --- 1 20 --- --- --- --- --- --- --- --- 1 2,4 

39 --- --- 1 20 1 5,6 1 8,3 --- --- --- --- 3 5,1 

40 --- --- 1 25 --- --- 1 12,5 --- --- --- --- 2 7,1 

41 --- --- 5 45,5 4 33,3 1 6,7 --- --- 1 100 11 18,6 

42 --- --- --- --- 1 20 1 5,9 --- --- --- --- 2 6,3 

43 --- --- 1 50 3 37,5 --- --- 2 6,7 --- --- 6 11,8 

44 --- --- --- --- 2 22,2 1 8,3 --- --- --- --- 3 5,8 

45 --- --- 2 40 --- --- --- --- --- --- --- --- 2 5,7 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- 1 25 --- --- --- --- --- --- 1 3,8 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- 1 33,3 --- --- --- --- 1 12,5 --- --- 2 7,7 

51 --- --- 2 20 5 21,7 3 8,6 1 3,7 --- --- 11 9,2 

52 1 33,3 4 21,1 12 28,6 2 5,7 1 2,1 --- --- 20 13,6 

53 --- --- 2 33,3 1 16,7 --- --- --- --- --- --- 3 10 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 6 46,2 5 19,2 11 22 --- --- --- --- 22 15,9 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- 2 28,6 1 10 1 8,3 --- --- --- --- 4 7,7 

58 --- --- 2 50 2 15,4 --- --- 1 4,5 --- --- 5 8,8 

59 --- --- 1 50 --- --- --- --- --- --- --- --- 1 7,1 

60 --- --- --- --- --- --- 1 7,7 1 6,3 --- --- 2 5,1 

61 --- --- 2 22,2 --- --- --- --- --- --- --- --- 2 4,8 

62 --- --- 1 16,7 --- --- 2 22,2 --- --- --- --- 3 9,4 

63 --- --- 1 12,5 7 30,4 4 10,3 --- --- --- --- 12 10,2 

64 --- --- --- --- --- --- 1 11,1 --- --- --- --- 1 3,6 

65 --- --- 1 16,7 1 12,5 2 20 --- --- --- --- 4 10,5 

66 --- --- 1 20 1 4,3 1 5 --- --- --- --- 3 4,5 

67 --- --- 5 31,3 6 20,7 --- --- --- --- --- --- 11 9,3 

68 --- --- 3 33,3 1 10 1 5,9 2 14,3 --- --- 7 14 

69 --- --- --- --- --- --- 1 16,7 --- --- --- --- 1 4,8 

70 --- --- 1 20 4 16 --- --- --- --- --- --- 5 4,5 

71 --- --- --- --- 2 33,3 --- --- --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 1 100 1 33,3 --- --- --- --- --- --- 2 22,2 

74 --- --- 6 35,3 1 4,2 1 4,3 1 3,8 1 3,4 10 8,3 

75 --- --- 4 33,3 --- --- 1 3,7 2 7,4 1 5,3 8 8,2 

76 --- --- 5 23,8 3 11,1 2 6,7 1 3,1 1 3,3 12 8,3 

77 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

78 --- --- --- --- --- --- 1 7,1 1 7,7 --- --- 2 4,2 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- 1 33,3 1 9,1 --- --- --- --- --- --- 2 5,1 




EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

81 --- --- --- --- 1 4,8 --- --- 2 4,9 --- --- 3 2,5 

82 --- --- 1 20 --- --- --- --- 1 5,3 1 6,7 3 4,9 

83 3 42,9 3 12 1 3,4 5 15,6 1 2,3 --- --- 13 7,5 

84 1 33,3 3 33,3 3 16,7 1 6,3 --- --- --- --- 8 9,2 

85 --- --- 1 25 1 12,5 1 20 2 15,4 --- --- 5 14,7 

86 --- --- 1 25 4 22,2 --- --- --- --- --- --- 5 10,2 

87 --- --- --- --- --- --- 1 5 --- --- --- --- 1 1,6 

88 1 50 8 30,8 5 20 3 9,4 1 3,6 --- --- 18 13,2 

89 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,4 

90 --- --- --- --- --- --- 1 9,1 --- --- --- --- 1 1,5 

91 --- --- 1 25 --- --- --- --- --- --- 1 12,5 2 5,3 

92 --- --- 5 16,1 5 13,5 4 10,5 2 5,7 --- --- 16 11,2 

93 --- --- 13 39,4 7 20,6 3 6,5 5 8,8 3 6,1 31 14,2 

94 --- --- 3 11,5 2 5,3 1 3,3 --- --- 1 6,7 7 4,8 

96 --- --- 1 50 --- --- 2 15,4 2 9,1 --- --- 5 7,2 

TOTAL 12 14,6 163 21,1 162 12,6 99 6,4 62 2,9 22 2,7 520 7,8 

. 




EuroNeoNet 


6.10.2 PIVH (Grades III or IV) Rate by Gestational Age. 

Table 6.10.2 shows the PIVH (Grades III or IV) distribution according to 


Unit 

Code 

PIVH (Grades III or IV) Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 2 20 2 12,5 --- --- --- --- --- --- 4 5,5 

2 --- --- 1 50 --- --- --- --- 1 16,7 1 33,3 3 20 

3 2 40 4 28,6 3 17,6 1 3,8 --- --- --- --- 10 7,8 

4 --- --- 3 37,5 --- --- 1 7,7 --- --- --- --- 4 8 

5 1 12,5 2 20 2 5,4 --- --- 1 2,3 1 25 7 5,8 

6 1 25 6 35,3 2 7,1 --- --- 1 1,9 --- --- 10 6,9 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 50 2 15,4 --- --- 3 15,8 

9 --- --- --- --- 1 20 1 11,1 --- --- --- --- 2 6,1 

10 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 1,8 

11 --- --- 4 30,8 --- --- 5 13,9 2 4 --- --- 11 7,8 

12 1 100 15 48,4 10 16,9 9 8,2 10 6,3 2 2,7 47 10,9 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- 4 26,7 5 15,6 6 7,5 2 1,7 --- --- 17 5,6 

15 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 1,4 

16 1 100 --- --- --- --- --- --- --- --- --- --- 1 2,8 

17 --- --- --- --- 2 15,4 --- --- --- --- 1 5,9 3 3,5 

18 --- --- --- --- 2 20 1 6,7 1 4 --- --- 4 6,3 

19 --- --- 2 25 --- --- --- --- --- --- --- --- 2 3,1 

20 --- --- 2 25 --- --- --- --- --- --- 1 7,7 3 3,8 

21 --- --- 1 33,3 1 25 1 16,7 --- --- --- --- 3 7,5 

22 --- --- --- --- 1 11,1 1 6,7 --- --- --- --- 2 3,1 

23 --- --- 5 50 2 14,3 2 12,5 4 22,2 2 66,7 15 24,6 

24 1 100 5 33,3 7 14,3 3 5,2 --- --- --- --- 16 9,4 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 1 50 1 11,1 1 6,7 1 7,7 --- --- --- --- 4 6,1 

27 --- --- --- --- 4 40 2 11,1 1 14,3 --- --- 7 17,1 

28 --- --- --- --- 1 20 --- --- --- --- --- --- 1 5,6 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 1 50 6 50 3 20 --- --- --- --- --- --- 10 14,3 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- 3 42,9 1 14,3 --- --- --- --- --- --- 4 12,5 

33 --- --- 2 13,3 3 11,5 --- --- 1 2,3 --- --- 6 4,7 

34 --- --- --- --- 3 25 --- --- --- --- --- --- 3 7,1 

35 --- --- --- --- 1 14,3 --- --- --- --- --- --- 1 4 

36 --- --- 2 25 --- --- 1 6,7 1 5,6 1 5,6 5 7,5 

37 --- --- 1 50 --- --- 2 28,6 --- --- --- --- 3 9,4 

38 --- --- --- --- 1 14,3 --- --- --- --- --- --- 1 2,4 

39 1 50 --- --- --- --- 1 6,3 1 10 --- --- 3 5,1 

40 1 100 --- --- --- --- 1 12,5 --- --- --- --- 2 7,1 

41 --- --- 5 71,4 2 22,2 4 23,5 --- --- --- --- 11 18,6 

42 --- --- --- --- 2 22,2 --- --- --- --- --- --- 2 6,3 

43 --- --- 4 80 1 33,3 --- --- --- --- 1 5 6 11,8 

44 --- --- 1 25 2 25 --- --- --- --- --- --- 3 5,8 

45 --- --- 1 33,3 --- --- 1 6,7 --- --- --- --- 2 5,7 




EuroNeoNet 


Unit 

Code 

PIVH (Grades III or IV) Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- 1 20 --- --- --- --- --- --- 1 3,8 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- 1 20 1 14,3 --- --- --- --- 2 7,7 

51 2 66,7 2 13,3 2 11,1 4 14,3 1 2,6 --- --- 11 9,2 

52 1 50 10 37 7 29,2 2 6,3 --- --- --- --- 20 13,6 

53 --- --- 2 66,7 1 12,5 --- --- --- --- --- --- 3 10 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 1 50 3 30 14 36,8 3 8,8 1 3 --- --- 22 15,9 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 1 50 2 40 1 12,5 --- --- --- --- --- --- 4 7,7 

58 1 100 2 40 1 12,5 1 9,1 --- --- --- --- 5 8,8 

59 --- --- --- --- 1 100 --- --- --- --- --- --- 1 7,1 

60 --- --- --- --- --- --- 1 12,5 1 7,1 --- --- 2 5,1 

61 --- --- 2 40 --- --- --- --- --- --- --- --- 2 4,8 

62 --- --- 1 25 2 22,2 --- --- --- --- --- --- 3 9,4 

63 --- --- 3 42,9 5 22,7 4 16 --- --- --- --- 12 10,2 

64 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,6 

65 --- --- 1 20 3 33,3 --- --- --- --- --- --- 4 10,5 

66 1 50 --- --- 2 18,2 --- --- --- --- --- --- 3 4,5 

67 --- --- 7 43,8 4 20 --- --- --- --- --- --- 11 9,3 

68 1 100 2 50,0 2 13,3 2 15,4 --- --- --- --- 7 14 

69 --- --- --- --- --- --- --- --- --- --- 1 10 1 4,8 

70 --- --- 2 18,2 3 17,6 --- --- --- --- --- --- 5 4,5 

71 --- --- 2 28,6 --- --- --- --- --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 1 50 1 50 --- --- --- --- --- --- 2 22,2 

74 --- --- 6 46,2 1 4,2 2 5,7 1 2 --- --- 10 8,3 

75 --- --- 4 33,3 --- --- --- --- 3 8,1 1 6,7 8 8,2 

76 --- --- 7 36,8 2 8,7 1 3,8 2 3,6 --- --- 12 8,3 

77 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

78 --- --- --- --- --- --- 2 12,5 --- --- --- --- 2 4,2 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- --- --- 2 20 --- --- --- --- --- --- 2 5,1 

81 --- --- --- --- 2 11,8 --- --- --- --- 1 5,6 3 2,5 

82 --- --- --- --- 1 9,1 1 6,7 1 3,8 --- --- 3 4,9 

83 6 66,7 --- --- 1 2,9 4 9,5 2 3 --- --- 13 7,5 

84 --- --- 4 36,4 4 26,7 --- --- --- --- --- --- 8 9,2 

85 --- --- 1 16,7 1 20 2 25 1 8,3 --- --- 5 14,7 

86 --- --- 3 50 1 9,1 1 11,1 --- --- --- --- 5 10,2 

87 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,6 

88 2 50 12 52,2 1 3,4 1 3,4 2 4,7 --- --- 18 13,2 

89 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,4 

90 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 1,5 

91 --- --- 1 25 --- --- --- --- 1 7,7 --- --- 2 5,3 

92 1 25 6 20 6 16,2 3 7,1 --- --- --- --- 16 11,2 

93 3 42,9 10 43,5 8 26,7 8 17,4 2 2,4 --- --- 31 14,2 

94 2 40 3 9,7 --- --- 1 2,9 1 3,2 --- --- 7 4,8 

96 --- --- 1 50 --- --- 2 11,8 1 3,2 1 14,3 5 7,2 

TOTAL 33 39,3 185 28 149 12,9 91 5,7 48 2,2 14 1,4 520 7,8 




EuroNeoNet 


6.10.3 PIVH (Grades III or IV) Standardized Rate by Perinatal Risk Factors. 

Graph 6.10.3, corresponds to the 95% CI for the standardised PIVH (Grades III or IV) rate adjusted. 

Graph 6.10.3 

The results for Units 1, 5, 15, 19, 33, 70, 81 and 94 reached statistical significant relevance, being the PIVH (Grades III or VI) 

rate for these Units significantly smaller than the one expected according to the standard’s population PIVH (Grades III or 

IV) distribution. On the other hand, Units 12, 30 and 35 had a bigger significant PIVH (Grades III or IV) rate than the one 

expected according to the standard’s population PIVH (Grades III or IV) distribution. 

Units 13, 25, 29, 31, 46, 48, 49, 54, 56, 77 and 79 didn’t register PIVH (Grades III or IV). 

Note 1: Standardization items: Gender, Prenatal Steroids use, 1-min Apgar Score, 5-min apgar 

Score. Mode of Delivery and Major Birth Defects. 



Note: Excluded babies died in Delivery Room and babies without cranial imaging done.Analyzed population: Admitted babies with a cranial imaging done.

EuroNeoNet 


6.11 NEC Rate. 

Definition: if the infant had NEC diagnosed at surgery, at postmortem examination or clinically 

and radiographically using the following criteria: 

A. - One or more of the following clinical signs present: 

1. - Bilious gastric aspirate or emesis 

2. - Abdominal distension 

3. - Occult or gross blood in stool (no fissure) 

AND 

B. - One or more of the following radiographic findings present: 

1. - Pneumatosis intestinalis (cystic or linear) 

2. - Hepato-biliary gas 

3. – Pneumoperitoneum 

Note 1: Infants should be coded as having FOCAL GASTROINTESTINAL PERFORATION, not 

as NEC even if satisfying the definition of NEC but, are found at surgery or postmortem 

examination for that episode to have a Focal Gastrointestinal Perforation. 

6.11.1 NEC Rate by Birth Weight. 

The global NEC rate for 2010 cohort has been of 5.5%, with a variation of 0.8% 

and 21.1% within units. 

Unit 

Code 

NEC Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- --- --- 2 13,3 1 4,8 --- --- --- --- 3 3,2 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 --- --- 4 25 8 34,8 2 5,4 --- --- --- --- 14 9 

4 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,4 

5 1 33,3 4 19 --- --- --- --- 1 2,6 --- --- 6 3,6 

6 1 11,1 4 25 1 2,9 1 3,7 --- --- --- --- 7 4,1 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- 1 14,3 --- --- 1 6,3 1 7,1 --- --- 3 4,9 

11 --- --- --- --- 6 24 1 3 1 2,1 --- --- 8 5,5 

12 2 66,7 12 21,4 6 7,4 11 11,1 2 1,3 4 4,6 37 7,7 

13 --- --- --- --- 1 20 --- --- 2 16,7 --- --- 3 12 

14 2 66,7 3 9,1 8 17 5 7,5 2 1,6 1 2 21 6,5 

15 --- --- 3 50 2 9,1 --- --- --- --- --- --- 5 6 

16 --- --- --- --- 1 25 1 25 1 5,3 --- --- 3 7,5 

17 --- --- 1 11,1 1 7,1 --- --- 4 14,3 1 7,7 7 7,8 

18 --- --- --- --- --- --- --- --- 2 9,1 --- --- 2 2,9 

19 --- --- --- --- --- --- 1 6,7 --- --- --- --- 1 1,5 

20 --- --- --- --- --- --- 1 6,3 --- --- --- --- 1 1,3 

21 --- --- --- --- --- --- --- --- --- --- 1 25 1 2,4 

22 --- --- --- --- 1 9,1 --- --- --- --- 1 6,3 2 3,1 

23 --- --- 5 50 2 16,7 3 16,7 1 6,7 2 7,4 13 15,9 

24 --- --- --- --- 2 3,5 4 8,2 --- --- --- --- 6 3,5 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- 1 5,3 --- --- --- --- 1 4,5 --- --- 2 2,9 

27 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 2,1 

28 --- --- --- --- 3 37,5 1 50 --- --- --- --- 4 21,1 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 4 40 2 10 --- --- 1 3 --- --- 7 9,5 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

31 --- --- --- --- --- --- 1 50 --- --- --- --- 1 9,1 

32 1 50 3 50 2 28,6 --- --- --- --- --- --- 6 18,8 

33 --- --- --- --- 1 3,2 1 2,9 3 5,8 --- --- 5 3,6 

34 --- --- 2 33,3 1 9,1 --- --- --- --- --- --- 3 7,3 

35 --- --- 2 33,3 1 12,5 --- --- --- --- --- --- 3 12 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- 1 33,3 1 33,3 --- --- 2 9,5 --- --- 4 10,3 

38 1 100 1 20 --- --- 1 10 --- --- --- --- 3 7,1 

39 --- --- 1 20 1 5,6 2 16,7 --- --- --- --- 4 6,8 

40 --- --- --- --- --- --- 1 12,5 --- --- --- --- 1 3,2 

41 --- --- 2 18,2 1 8,3 --- --- 2 9,5 --- --- 5 8,3 

42 --- --- 1 50 2 33,3 4 22,2 --- --- --- --- 7 20,6 

43 --- --- --- --- --- --- 1 9,1 --- --- --- --- 1 1,9 

44 --- --- 2 33,3 5 55,6 2 16,7 1 4 --- --- 10 19,2 

45 --- --- 1 20 --- --- 1 8,3 1 6,3 --- --- 3 7,5 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 4,5 

50 --- --- --- --- 1 12,5 1 14,3 1 12,5 --- --- 3 11,1 

51 1 50 1 9,1 3 13 1 2,9 1 3,6 1 4,5 8 6,6 

52 --- --- 3 15,8 4 9,5 2 5,4 --- --- --- --- 9 6 

53 --- --- --- --- 1 16,7 --- --- 1 7,7 --- --- 2 6,7 

54 --- --- --- --- --- --- --- --- 1 14,3 --- --- 1 7,7 

55 --- --- 4 20 5 13,9 8 13,3 2 2,9 --- --- 19 10,3 

56 --- --- --- --- --- --- 1 16,7 --- --- --- --- 1 5,9 

57 --- --- --- --- 2 18,2 --- --- 2 8,7 --- --- 4 7,4 

58 --- --- 1 25 1 7,7 1 5,6 --- --- --- --- 3 4,9 

59 --- --- --- --- --- --- --- --- 1 14,3 --- --- 1 7,1 

60 --- --- --- --- --- --- 1 7,7 --- --- --- --- 1 2,5 

61 --- --- 2 22,2 2 22,2 --- --- 1 7,7 --- --- 5 11,1 

62 --- --- --- --- 1 16,7 2 22,2 --- --- --- --- 3 9,1 

63 --- --- 2 25 3 12,5 --- --- --- --- --- --- 5 4,1 

64 --- --- --- --- --- --- 2 16,7 1 4,3 --- --- 3 7,3 

65 --- --- 1 16,7 1 12,5 1 10 --- --- --- --- 3 7,9 

66 --- --- --- --- --- --- 1 4,8 --- --- --- --- 1 1,4 

67 --- --- 4 22,2 4 13,3 4 12,5 1 2,3 --- --- 13 10,4 

68 --- --- --- --- 1 8,3 1 5,6 --- --- --- --- 2 3,6 

69 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 4,5 

70 --- --- --- --- 3 12 --- --- 2 5,3 --- --- 5 4,3 

71 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 1 33,3 1 20 3 23,1 --- --- --- --- 5 20 

74 --- --- 1 5,9 --- --- --- --- --- --- --- --- 1 0,8 

75 --- --- 2 16,7 2 16,7 1 3,6 --- --- --- --- 5 5 

76 1 25 2 9,5 1 3,6 1 3,3 --- --- --- --- 5 3,4 

77 1 33,3 --- --- --- --- --- --- --- --- --- --- 1 1,5 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

81 --- --- --- --- 1 4,8 --- --- --- --- --- --- 1 0,8 

82 --- --- --- --- --- --- --- --- 1 5,3 1 6,7 2 3,2 

83 --- --- 2 8 2 6,9 1 3,1 2 4,7 --- --- 7 4 

84 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- 2 11,1 --- --- --- --- --- --- 2 4 

87 --- --- --- --- 1 25 --- --- 1 4,3 --- --- 2 2,9 

88 --- --- 3 11,1 2 7,7 2 5,7 --- --- 2 7,7 9 5,8 

89 --- --- --- --- 2 66,7 --- --- --- --- --- --- 2 4,3 

90 --- --- --- --- --- --- --- --- --- --- 1 4,5 1 1,4 

91 --- --- 1 20 1 20 1 11,1 2 12,5 2 16,7 7 14,9 

92 --- --- 8 22,9 4 9,5 3 5,9 5 8,5 --- --- 20 10,5 

93 --- --- 9 23,7 1 2,9 2 4,3 1 1,7 2 3,9 15 6,1 

94 1 9,1 1 3,8 --- --- 2 6,7 --- --- 1 6,7 5 3,4 

95 --- --- 1 10 3 25 2 28,6 --- --- --- --- 6 10,3 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 12 11,2 110 13 116 8,5 91 5,4 55 2,3 20 2,1 404 5,5 



EuroNeoNet 


6.11.2 NEC Rate by Gestational Age. 

Table 6.11.2 shows the NEC distribution according to gestational age for each 

Unit. 

Unit 

Code 

NEC Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 2 20 1 5,9 --- --- --- --- --- --- 3 3,2 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 2 40 7 50 2 10,5 2 6,1 1 1,4 --- --- 14 9 

4 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,4 

5 3 33,3 1 9,1 1 2,5 --- --- --- --- 1 9,1 6 3,6 

6 --- --- 4 21,1 2 6,9 --- --- --- --- 1 6,7 7 4,1 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

10 --- --- --- --- 1 25 2 14,3 --- --- --- --- 3 4,9 

11 --- --- 2 15,4 3 15,8 1 2,7 1 1,9 1 4,2 8 5,5 

12 --- --- 10 27 11 16,4 9 7,8 4 2,3 3 3,6 37 7,7 

13 --- --- --- --- 1 50 --- --- 2 22,2 --- --- 3 12 

14 --- --- 3 18,8 9 25,7 5 6,2 2 1,6 2 3,1 21 6,5 

15 --- --- 1 25 1 6,7 2 11,8 1 4 --- --- 5 6 

16 --- --- --- --- 1 25 --- --- --- --- 2 16,7 3 7,5 

17 --- --- --- --- 1 6,3 2 8,7 3 9,7 1 5,9 7 7,8 

18 --- --- --- --- --- --- 1 6,3 1 3,8 --- --- 2 2,9 

19 --- --- --- --- 1 25 --- --- --- --- --- --- 1 1,5 

20 --- --- --- --- --- --- 1 10 --- --- --- --- 1 1,3 

21 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 2,4 

22 --- --- --- --- 1 11,1 --- --- 1 4,3 --- --- 2 3,1 

23 --- --- 3 37,5 5 50 2 11,8 3 9,1 --- --- 13 15,9 

24 --- --- --- --- 3 6,3 2 3,3 1 2,1 --- --- 6 3,5 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 1 50 --- --- --- --- --- --- 1 5,3 --- --- 2 2,9 

27 --- --- --- --- --- --- --- --- 1 12,5 --- --- 1 2,1 

28 --- --- --- --- 2 40 1 25 --- --- 1 25 4 21,1 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 1 50 2 16,7 3 18,8 --- --- 1 5,6 --- --- 7 9,5 

31 --- --- --- --- --- --- --- --- 1 33,3 --- --- 1 9,1 

32 --- --- 3 42,9 2 28,6 1 14,3 --- --- --- --- 6 18,8 

33 --- --- --- --- 1 3,6 1 4,2 2 4 1 5 5 3,6 

34 --- --- --- --- 2 18,2 --- --- 1 14,3 --- --- 3 7,3 

35 --- --- 2 66,7 1 14,3 --- --- --- --- --- --- 3 12 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- 1 33,3 --- --- --- --- 2 13,3 1 10 4 10,3 

38 --- --- --- --- 2 28,6 1 9,1 --- --- --- --- 3 7,1 

39 --- --- --- --- 1 6,7 2 12,5 1 10 --- --- 4 6,8 

40 --- --- --- --- --- --- 1 10 --- --- --- --- 1 3,2 

41 --- --- 1 14,3 1 11,1 --- --- 1 8,3 2 13,3 5 8,3 

42 --- --- 1 50 --- --- 1 12,5 5 55,6 --- --- 7 20,6 

43 --- --- --- --- --- --- --- --- 1 5,9 --- --- 1 1,9 

44 --- --- --- --- 5 62,5 4 33,3 --- --- 1 5,3 10 19,2 

45 --- --- 1 33,3 --- --- 1 5,9 1 14,3 --- --- 3 7,5 



EuroNeoNet 


Unit 

Code 

NEC Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- 1 100 --- --- --- --- --- --- --- --- 1 4,5 

50 --- --- 1 25 --- --- 1 14,3 1 14,3 --- --- 3 11,1 

51 1 25 2 13,3 1 5,6 2 7,1 1 2,6 1 5,9 8 6,6 

52 1 50 3 11,1 4 16,7 1 3,1 --- --- --- --- 9 6 

53 --- --- --- --- 1 12,5 1 20 --- --- --- --- 2 6,7 

54 --- --- --- --- --- --- --- --- 1 20 --- --- 1 7,7 

55 --- --- 3 21,4 8 15,7 6 13,6 --- --- 2 6,3 19 10,3 

56 --- --- --- --- --- --- --- --- 1 33,3 --- --- 1 5,9 

57 --- --- 1 20 --- --- 1 7,7 2 20 --- --- 4 7,4 

58 --- --- 1 20 --- --- --- --- 2 10 --- --- 3 4,9 

59 --- --- --- --- --- --- --- --- --- --- 1 20 1 7,1 

60 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 2,5 

61 --- --- 1 20 1 12,5 3 33,3 --- --- --- --- 5 11,1 

62 --- --- --- --- 2 22,2 1 25 --- --- --- --- 3 9,1 

63 --- --- --- --- 3 12,5 2 8 --- --- --- --- 5 4,1 

64 --- --- --- --- --- --- 1 11,1 1 8,3 1 8,3 3 7,3 

65 --- --- --- --- 2 22,2 1 8,3 --- --- --- --- 3 7,9 

66 --- --- --- --- --- --- 1 4 --- --- --- --- 1 1,4 

67 --- --- 4 22,2 4 17,4 4 10 --- --- 1 5,9 13 10,4 

68 --- --- --- --- 1 5,9 1 7,1 --- --- --- --- 2 3,6 

69 1 100 --- --- --- --- --- --- --- --- --- --- 1 4,5 

70 --- --- 1 8,3 1 5,9 2 8,7 1 2,3 --- --- 5 4,3 

71 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- 5 62,5 --- --- --- --- 5 20 

74 --- --- --- --- --- --- 1 2,9 --- --- --- --- 1 0,8 

75 --- --- 2 16,7 2 15,4 --- --- 1 2,6 --- --- 5 5 

76 --- --- 1 5,3 2 8,3 1 3,8 --- --- 1 4,8 5 3,4 

77 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,5 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- 1 5,6 --- --- --- --- --- --- 1 0,8 

82 --- --- --- --- --- --- --- --- 2 7,7 --- --- 2 3,2 

83 --- --- 1 8,3 3 8,8 1 2,4 2 3 --- --- 7 4 

84 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- 2 18,2 --- --- --- --- --- --- 2 4 

87 --- --- --- --- --- --- 2 16,7 --- --- --- --- 2 2,9 

88 --- --- 2 8,7 2 6,7 4 12,9 1 2,2 --- --- 9 5,8 

89 --- --- --- --- 1 33,3 1 10 --- --- --- --- 2 4,3 

90 --- --- --- --- --- --- --- --- 1 2,7 --- --- 1 1,4 

91 --- --- 1 25 2 40 3 21,4 1 5,6 --- --- 7 14,9 

92 --- --- 6 18,2 4 9,1 8 16,7 2 5,4 --- --- 20 10,5 

93 1 4,8 6 23,1 3 9,7 3 6,3 2 2,3 --- --- 15 6,1 

94 2 40 --- --- 2 6,3 --- --- 1 3,2 --- --- 5 3,4 

95 --- --- 1 11,1 1 50 2 15,4 1 5,3 1 9,1 6 10,3 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 13 11,3 83 11,6 118 9,6 101 6 64 2,6 25 2,2 404 5,5 



EuroNeoNet 


6.11.3 NEC Standardized Rate by Perinatal Firsk Factors. 

Graph 6.11.3 corresponds to the 95% CI for the standardised NEC rate adjusted. 

Graph 6.11.3 

The results for Units 4, 19, 20, 24, 66, 74, 77, 81 and 90 reached statistical significant relevance, being the NEC rate for 

these Units significantly smaller than the one expected according to the standard’s population NEC distribution. On the 

other hand, Unit 44 had a bigger significant NEC rate than the one expected according to the standard’s population NEC 

distribution. 

Units 2, 8, 9, 25, 29, 36, 46, 47, 48, 71, 78, 79, 80, 84, 85 and 96 didn’t register NEC 





EuroNeoNet 


6.12 Focal Gastrointestinal Perforation Rate. 

Definition: if the infant had a Focal Gastrointestinal Perforation separate from NEC. This 

diagnosis will be based on visual inspection of the bowel at the time of surgery or postmortem 

examination that demonstrates a single focal perforation with the remainder of the bowel 

appearing normal. 

6.12.1 Focal Gastrointestinal Perforation Rate by Birth Weight. 

The global Focal Gastrointestinal Perforation rate for 2010 cohort has been of 

1.8%, with a variation of 0.6% and 10.5% within units. 

Focal Gastrointestinal Perforation Rate against Birth Weight by Participating Unit 

Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

4 --- --- --- --- --- --- --- --- 1 4,8 --- --- 1 1,4 

5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

6 --- --- 1 6,3 --- --- --- --- --- --- --- --- 1 0,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- --- --- 2 13,3 --- --- 2 5,6 

10 --- --- --- --- 3 42,9 --- --- --- --- --- --- 3 4,9 

11 --- --- --- --- 2 8 --- --- --- --- --- --- 2 1,4 

12 --- --- 6 10,7 2 2,5 4 4 1 0,6 1 1,1 14 2,9 

13 --- --- --- --- 1 20 --- --- --- --- --- --- 1 4 

14 --- --- 2 6,1 2 4,3 1 1,5 1 0,8 --- --- 6 1,9 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- --- --- 1 3,6 --- --- 1 1,1 

18 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- --- --- 2 11,1 --- --- --- --- --- --- 2 2,5 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

23 --- --- 3 23,1 4 19 --- --- --- --- --- --- 7 6,5 

24 --- --- --- --- 2 3,5 1 2 --- --- --- --- 3 1,7 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- 1 7,1 --- --- --- --- --- --- 1 1,4 

27 --- --- --- --- 1 8,3 1 11,1 1 4,8 --- --- 3 6,3 

28 --- --- --- --- 2 25 --- --- --- --- --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 1 10 2 10 --- --- --- --- --- --- 3 4,1 

31 --- --- --- --- --- --- 1 50 --- --- --- --- 1 9,1 

32 1 50 --- --- --- --- --- --- --- --- --- --- 1 3,1 

33 --- --- --- --- 3 9,7 1 2,9 --- --- --- --- 4 2,9 

34 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 2,4 

35 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 4 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 1 100 --- --- --- --- --- --- --- --- --- --- 1 2,5 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

39 --- --- --- --- --- --- 1 8,3 --- --- --- --- 1 1,7 

40 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

43 --- --- --- --- --- --- 1 9,1 --- --- --- --- 1 1,9 

44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

45 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 3,4 

49 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 4,5 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 1 50 --- --- 1 4,3 2 5,7 1 3,6 1 4,5 6 5 

52 1 33,3 1 5,3 3 7,1 1 2,7 --- --- --- --- 6 4 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 1 100 --- --- --- --- --- --- --- --- --- --- 1 7,7 

55 --- --- 2 10 4 11,1 --- --- --- --- --- --- 6 3,2 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 1,9 

58 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

61 --- --- 1 11,1 --- --- --- --- --- --- --- --- 1 2,2 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- --- --- 3 12,5 1 2,5 1 2 --- --- 5 4,1 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- 1 5,6 2 6,7 2 6,3 --- --- --- --- 5 4 

68 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- --- --- 3 12 1 5 1 2,6 --- --- 5 4,3 

71 --- --- --- --- 1 16,7 1 16,7 --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- 1 5,9 --- --- --- --- --- --- --- --- 1 0,8 

75 --- --- 1 8,3 --- --- --- --- --- --- --- --- 1 1 

76 --- --- 1 4,8 1 3,6 --- --- 1 3 --- --- 3 2,1 

77 1 33,3 --- --- --- --- --- --- --- --- --- --- 1 1,5 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- 1 9,1 --- --- --- --- --- --- --- --- 1 1,2 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

82 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 1,6 

83 --- --- 1 4 --- --- --- --- --- --- --- --- 1 0,6 

84 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

85 --- --- 1 25 --- --- 1 20 --- --- --- --- 2 5,9 

86 --- --- --- --- 1 5,6 --- --- --- --- --- --- 1 2 

87 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

88 --- --- 1 3,7 --- --- 2 5,7 --- --- --- --- 3 1,9 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- 1 20 --- --- --- --- --- --- --- --- 1 2,1 

92 --- --- 2 5,7 3 7,1 --- --- 1 1,7 --- --- 6 3,2 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 1 9,1 1 3,8 --- --- --- --- --- --- --- --- 2 1,4 

95 --- --- 1 10 --- --- 1 14,3 --- --- --- --- 2 3,4 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 7 6,5 32 3,8 51 3,7 23 1,4 14 0,6 2 0,2 129 1,8 



EuroNeoNet 


6.12.2 Focal Gastrointestinal Perforation Rate by Gestational Age. 

Table 6.12.2 shows the Focal Gastrointestinal Perforation distribution 

according to gestational age for each Unit. 

Focal Gastrointestinal Perforation Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

4 --- --- --- --- --- --- 1 7,1 --- --- --- --- 1 1,4 

5 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

6 1 12,5 --- --- --- --- --- --- --- --- --- --- 1 0,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- 1 16,7 1 11,1 --- --- --- --- 2 5,6 

10 --- --- --- --- 3 75 --- --- --- --- --- --- 3 4,9 

11 --- --- 1 7,7 1 5,3 --- --- --- --- --- --- 2 1,4 

12 --- --- 4 10,8 3 4,5 3 2,6 4 2,3 --- --- 14 2,9 

13 --- --- --- --- 1 50 --- --- --- --- --- --- 1 4 

14 --- --- --- --- 4 11,4 1 1,2 1 0,8 --- --- 6 1,9 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- 1 4,3 --- --- --- --- 1 1,1 

18 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- 2 25 --- --- --- --- --- --- --- --- 2 2,5 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

23 --- --- 4 30,8 3 23,1 --- --- --- --- --- --- 7 6,5 

24 --- --- --- --- 3 6,1 --- --- --- --- --- --- 3 1,7 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- 1 6,7 --- --- --- --- --- --- 1 1,4 

27 --- --- --- --- 1 8,3 1 5 1 12,5 --- --- 3 6,3 

28 --- --- --- --- 2 40 --- --- --- --- --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 1 8,3 2 12,5 --- --- --- --- --- --- 3 4,1 

31 --- --- --- --- --- --- --- --- 1 33,3 --- --- 1 9,1 

32 --- --- 1 14,3 --- --- --- --- --- --- --- --- 1 3,1 

33 --- --- --- --- 3 10,7 --- --- 1 2 --- --- 4 2,9 

34 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 2,4 

35 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 4 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 2,5 

39 --- --- --- --- --- --- --- --- 1 10 --- --- 1 1,7 

40 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

43 --- --- --- --- --- --- --- --- 1 5,9 --- --- 1 1,9 

44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

45 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



EuroNeoNet 


Focal Gastrointestinal Perforation Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- 1 14,3 --- --- 1 3,4 

49 --- --- 1 100 --- --- --- --- --- --- --- --- 1 4,5 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 --- --- 1 6,7 --- --- 3 10,7 1 2,6 1 5,9 6 5 

52 --- --- 2 7,4 --- --- 2 6,3 2 5,3 --- --- 6 4 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 7,7 

55 --- --- 2 14,3 2 3,9 2 4,5 --- --- --- --- 6 3,2 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- --- --- --- --- 1 7,7 --- --- --- --- 1 1,9 

58 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

61 --- --- 1 20 --- --- --- --- --- --- --- --- 1 2,2 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- 1 14,3 2 8,3 1 4 --- --- 1 3,3 5 4,1 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- 3 16,7 1 4,3 1 2,5 --- --- --- --- 5 4 

68 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- --- --- 3 17,6 1 4,3 1 2,3 --- --- 5 4,3 

71 --- --- --- --- 1 16,7 --- --- 1 12,5 --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- 1 7,7 --- --- --- --- --- --- --- --- 1 0,8 

75 --- --- 1 8,3 --- --- --- --- --- --- --- --- 1 1 

76 --- --- 1 5,3 1 4,2 --- --- --- --- 1 4,8 3 2,1 

77 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,5 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,2 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

82 --- --- --- --- --- --- --- --- 1 3,8 --- --- 1 1,6 

83 1 11,1 --- --- --- --- --- --- --- --- --- --- 1 0,6 

84 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

85 1 100 --- --- --- --- --- --- 1 8,3 --- --- 2 5,9 

86 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 2 

87 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

88 --- --- --- --- 2 6,7 1 3,2 --- --- --- --- 3 1,9 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- 1 20 --- --- --- --- --- --- 1 2,1 

92 --- --- 3 9,1 1 2,3 2 4,2 --- --- --- --- 6 3,2 

93 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

94 --- --- 1 3,1 1 3,1 --- --- --- --- --- --- 2 1,4 

95 --- --- 1 11,1 --- --- 1 7,7 --- --- --- --- 2 3,4 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 3 2,6 36 5 46 3,7 23 1,4 18 0,7 3 0,3 129 1,8 



EuroNeoNet 


6.12.3 Focal Gastrointestinal Perforation Standardized Rate by Perinatal Risk Factors. 

Graph 6.12.3 corresponds to the 95% CI for the standardised focal gastrointestinal perforation adjusted rate. 

Graph 6.12.3 

The results for Unit 83 reached statistical significant relevance, being the focal gastrointestinal perforation rate for these 

Units significantly smaller than the one expected according to the standard’s population focal gastrointestinal perforation 

distribution. On the other hand none Unit had a bigger significant focal gastrointestinal perforation rate than the one 

expected according to the standard’s population focal gastrointestinal distribution. 

Units 1, 2, 3, 5, 8, 15, 16, 18, 19, 21, 22, 25, 29, 36, 37, 40, 41, 42, 44, 45, 46, 47, 50, 53, 56, 58, 59, 60, 62, 64, 65, 66, 68, 69, 73, 

78, 80, 81, 84, 87, 89, 90, 93 and 96 didn’t register focal gastrointestinal perforarion. 





EuroNeoNet 


6.13 ROP (Grades >=3)Rate. 

Definition: if an indirect ophthalmologic examination for ROP was performed at any time, the 

WORST grade, according to the following classification is registered. 

Grade 0 – No evidence of ROP lesions. 

Grade 1 – White demarcation line between vascular and avascular retina. 

Grade 2 – Elevated demarcation line or ridge. 

Grade 3 – Ridge with extraretinal fibrovascular proliferation. 

Grade 4 – Subtotal retinal detachment. 

Grade 5 – Total retinal detachment. 

6.13.1 ROP (Grades >=3) Rate by Birth Weight. 

The global ROP (Grades >= 3) rate for 2010 cohort has been of 3.4%, with a 

variation of 2.6% and 100% within units. 

ROP (Grades >=III) Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- --- --- 2 15,4 1 6,3 --- --- --- --- 3 4,8 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 --- --- 2 22,2 2 10 --- --- --- --- --- --- 4 3,8 

4 --- --- 3 50 1 14,3 --- --- --- --- --- --- 4 9,8 

5 1 33,3 3 27,3 --- --- --- --- --- --- --- --- 4 3,4 

6 --- --- 2 14,3 4 15,4 --- --- --- --- --- --- 6 4,7 

8 --- --- --- --- --- --- 1 20 --- --- --- --- 1 8,3 

9 --- --- --- --- 1 33,3 1 11,1 1 10 --- --- 3 12 

10 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 4,1 

11 --- --- 3 30 2 9,1 2 8 --- --- --- --- 7 7 

12 --- --- 6 16,7 3 4,7 2 2,6 1 1 --- --- 12 3,6 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- 6 26,1 4 9,5 --- --- 1 1 --- --- 11 4,2 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

18 --- --- 1 33,3 1 14,3 --- --- --- --- --- --- 2 3,8 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- --- --- 1 7,1 --- --- --- --- --- --- 1 1,6 

21 --- --- --- --- 1 33,3 1 10 --- --- --- --- 2 6,3 

22 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

23 --- --- 2 8 --- --- --- --- --- --- --- --- 2 1,4 

24 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

28 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 4 50 2 14,3 --- --- --- --- --- --- 6 10,3 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- 1 25 --- --- --- --- --- --- --- --- 1 3,8 

33 --- --- 3 21,4 3 10 1 3,1 1 2,4 --- --- 8 6,7 

34 1 100 --- --- 1 14,3 --- --- --- --- --- --- 2 8,7 


Note: Excluded babies died in Delivery Room and without reinal exam done. Analyzed population: Admitted babies with 

retinal exam done.

EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

39 --- --- --- --- 1 7,1 1 10 --- --- --- --- 2 4,2 

40 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- --- --- 3 75 --- --- --- --- --- --- 3 12 

43 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

44 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 2,1 

45 --- --- 1 100 --- --- 1 14,3 --- --- --- --- 2 8,7 

46 1 100 --- --- --- --- --- --- --- --- --- --- 1 10 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 --- --- --- --- 2 10,5 1 4,8 --- --- --- --- 3 5,5 

52 --- --- 1 7,1 --- --- --- --- --- --- --- --- 1 0,9 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 3 30 1 4,3 1 2 1 2 --- --- 6 4,5 

56 --- --- --- --- --- --- --- --- 1 16,7 --- --- 1 6,7 

57 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 2,4 

58 --- --- 1 50 1 9,1 --- --- --- --- --- --- 2 4,1 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- 2 28,6 1 7,7 1 6,3 --- --- 4 10 

61 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- 1 25 1 6,7 --- --- --- --- --- --- 2 2,1 

64 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 3,4 

65 --- --- 2 50 1 20 --- --- --- --- --- --- 3 9,7 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- --- --- 1 3,8 --- --- --- --- --- --- 1 0,9 

68 --- --- 1 25 --- --- --- --- --- --- --- --- 1 2,2 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 1,4 

71 --- --- 2 28,6 --- --- --- --- --- --- --- --- 2 8 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- --- --- 3 14,3 --- --- --- --- --- --- 3 3 

75 --- --- --- --- 2 20 --- --- --- --- --- --- 2 2,3 

76 --- --- 3 15,8 2 9,5 --- --- --- --- --- --- 5 4,5 

77 --- --- 1 11,1 2 20 --- --- --- --- --- --- 3 4,7 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- 1 6,3 --- --- --- --- 1 5,9 2 2,4 

82 1 100 --- --- --- --- --- --- --- --- --- --- 1 2 

83 --- --- 3 16,7 1 3,8 --- --- --- --- --- --- 4 2,9 

84 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 1,5 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



retinal exam done.

EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

87 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

88 --- --- 1 9,1 2 15,4 1 5,9 --- --- --- --- 4 5,4 

89 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,9 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- 1 25 --- --- --- --- --- --- 1 3,4 

92 --- --- 4 36,4 5 35,7 --- --- --- --- --- --- 9 25,7 

93 --- --- 3 14,3 5 15,6 --- --- 2 4,2 --- --- 10 5,5 

94 1 12,5 5 38,5 1 4 --- --- --- --- --- --- 7 9,2 

95 --- --- --- --- 3 33,3 1 33,3 1 16,7 2 40 7 30,4 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 45 11,1 75 14,3 69 6,4 16 1,2 11 0,7 3 0,5 179 3,4 



retinal exam done.

EuroNeoNet 


6.13.2 ROP (Grades >=3) Rate by Gestational Age. 

Table 6.13.2 shows the ROP (Grades >= 3) distribution according to gestational 


Unit 

Code 

ROP (Grades >=III) Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 1 14,3 2 11,8 --- --- --- --- --- --- 3 4,8 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 --- --- 4 40 --- --- --- --- --- --- --- --- 4 3,8 

4 --- --- 4 66,7 --- --- --- --- --- --- --- --- 4 9,8 

5 2 40 --- --- 2 5,9 --- --- --- --- --- --- 4 3,4 

6 --- --- 4 33,3 2 8,3 --- --- --- --- --- --- 6 4,7 

8 --- --- --- --- --- --- 1 50 --- --- --- --- 1 8,3 

9 --- --- --- --- 1 20 1 11,1 1 14,3 --- --- 3 12 

10 --- --- 2 40 --- --- --- --- --- --- --- --- 2 4,1 

11 --- --- 3 27,3 --- --- 4 12,5 --- --- --- --- 7 7 

12 --- --- 3 18,8 6 11,3 3 2,9 --- --- --- --- 12 3,6 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- 5 55,6 3 10 2 2,6 1 1 --- --- 11 4,2 

15 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

18 --- --- 1 25 1 14,3 --- --- --- --- --- --- 2 3,8 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 1,6 

21 --- --- 1 100 --- --- --- --- 1 5,9 --- --- 2 6,3 

22 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

23 1 100 --- --- 1 2,9 --- --- --- --- --- --- 2 1,4 

24 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

28 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 4 50 2 15,4 --- --- --- --- --- --- 6 10,3 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 100 --- --- --- --- --- --- --- --- --- --- 1 3,8 

33 --- --- 4 30,8 3 12 --- --- 1 2,2 --- --- 8 6,7 

34 --- --- 2 66,7 --- --- --- --- --- --- --- --- 2 8,7 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

37 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

38 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

39 --- --- --- --- 1 9,1 1 7,1 --- --- --- --- 2 4,2 

40 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- 1 100 2 28,6 --- --- --- --- --- --- 3 12 

43 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

44 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 2,1 



retinal exam done.

EuroNeoNet 


Unit 

Code 

ROP (Grades >=III) Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

45 --- --- 1 100 --- --- 1 7,7 --- --- --- --- 2 8,7 

46 --- --- --- --- 1 100 --- --- --- --- --- --- 1 10 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 --- --- 1 7,7 1 6,3 1 5,6 --- --- --- --- 3 5,5 

52 --- --- 1 5 --- --- --- --- --- --- --- --- 1 0,9 

53 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 3 42,9 2 5,7 --- --- 1 2,7 --- --- 6 4,5 

56 --- --- --- --- --- --- 1 20 --- --- --- --- 1 6,7 

57 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,4 

58 --- --- 1 33,3 1 14,3 --- --- --- --- --- --- 2 4,1 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- 1 25 --- --- 1 12,5 2 13,3 --- --- 4 10 

61 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- --- --- 2 14,3 --- --- --- --- --- --- 2 2,1 

64 --- --- --- --- --- --- --- --- 1 11,1 --- --- 1 3,4 

65 --- --- 1 50 2 28,6 --- --- --- --- --- --- 3 9,7 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- 1 9,1 --- --- --- --- --- --- --- --- 1 0,9 

68 --- --- 1 100 --- --- --- --- --- --- --- --- 1 2,2 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 20 --- --- --- --- --- --- --- --- 1 1,4 

71 --- --- 1 20 1 20 --- --- --- --- --- --- 2 8 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- 1 10 2 9,5 --- --- --- --- --- --- 3 3 

75 --- --- 1 25 1 7,7 --- --- --- --- --- --- 2 2,3 

76 --- --- 4 28,6 1 5,3 --- --- --- --- --- --- 5 4,5 

77 --- --- 1 11,1 2 22,2 --- --- --- --- --- --- 3 4,7 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- 1 7,1 1 3,6 --- --- --- --- 2 2,4 

82 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 2 

83 --- --- 2 20 1 3,2 1 2,9 --- --- --- --- 4 2,9 

84 1 50 --- --- --- --- --- --- --- --- --- --- 1 1,5 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

87 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

88 --- --- 2 25 2 11,1 --- --- --- --- --- --- 4 5,4 

89 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,9 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- 1 50 --- --- --- --- --- --- --- --- 1 3,4 

92 --- --- 6 46,2 2 13,3 1 16,7 --- --- --- --- 9 25,7 

93 --- --- 6 35,3 --- --- 3 7,9 1 1,4 --- --- 10 5,5 

94 2 66,7 5 20,8 --- --- --- --- --- --- --- --- 7 9,2 

95 --- --- --- --- 1 50 4 44,4 1 11,1 1 33,3 7 30,4 

96 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

TOTAL 29 24,1 85 19,8 50 5,1 26 1,9 10 0,6 1 0,1 179 3,4 



retinal exam done.

EuroNeoNet 


6.13.3 ROP (Grades >=3) Standardized Rate by Perinatal Risk Factors. 

Graph 6.13.3 corresponds to the 95% CI for the standardised ROP (Grades >= 3) rate adjusted rate. 

Graph 6.13.3 

The results for Units 12, 20, 23, 52, 63, 67, 75, 81, 83, 84, 91 and 93 reached statistical significant relevance, being the ROP 

(Grades >=3) rate for these Units significantly smaller than the one expected according to the standard’s population rop 

(Grades >=3) distribution. On the other hand none Unit had a bigger significant ROP (Grades >=3) rate than the one 

expected according to the standard’s population ROP (Grades >=3) distribution. 

Units 2, 13, 15, 16, 17, 19, 22, 24, 25, 26, 27, 28, 29, 31, 35, 36, 37, 38, 40, 41, 43, 47, 48, 49, 50, 53, 54, 59, 61, 62, 66, 69, 73, 

78, 79, 80, 85, 86, 87, 90 and 96 didn’t register ROP (Grades >0). 

Note 1: Standardization items: Birth weight Z-Score by gestational age , 1-min Apgar Score, 5- 

min apgar Score and Mode of Delivery. 



Note: Excluded babies died in Delivery Room and without reinal exam done. Analyzed population: Admitted babies with retinal exam done.

EuroNeoNet 


6.14 O 2 on day 28 Rate. 

Definition: if the infant was still in hospital and received any supplemental oxygen on day 28. 

Note 1: if the infant died or was discharged prior to day 28, and was not readmitted on or before 

day 28, the item is Not Applicable, so not listed in these results. 

Note 2: Excluded babies discharged before day 28. 

6.14.1 O 2 on day 28 Rate by Birth Weight. 

The global Supplemental Oxygen on day 28 rate for 2010 cohort has been of 


Supplemental Oxygen on day 28 Rate against Birth Weight by Participating Unit 

Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- 1 100 --- --- --- --- --- --- --- --- 1 100 

3 --- --- 3 75 3 100 --- --- --- --- --- --- 6 85,7 

4 --- --- 3 100 1 100 --- --- --- --- --- --- 4 100 

5 2 100 6 100 1 100 --- --- --- --- --- --- 9 100 

6 1 100 1 100 1 100 --- --- --- --- --- --- 3 100 

8 --- --- --- --- --- --- 1 16,7 1 25 --- --- 2 15,4 

9 --- --- --- --- 1 33,3 5 83,3 4 36,4 1 50 11 50 

10 1 100 5 100 5 83,3 6 46,2 2 20 1 10 20 44,4 

11 1 100 5 62,5 3 14,3 1 6,7 --- --- --- --- 10 15,4 

12 1 100 32 94,1 39 59,1 19 24,7 14 18,2 3 6,8 108 36,1 

13 --- --- --- --- 1 33,3 1 50 --- --- --- --- 2 11,8 

14 1 100 20 83,3 15 38,5 11 18 7 9 --- --- 54 23,9 

15 --- --- 4 80 12 60 1 16,7 5 16,7 --- --- 22 31 

16 --- --- 1 100 2 50 --- --- --- --- --- --- 3 9,4 

17 --- --- 8 100 9 64,3 8 44,4 4 19 --- --- 29 42 

18 --- --- 2 66,7 6 85,7 4 21,1 3 20 2 33,3 17 34 

19 1 100 6 100 3 75 3 25 2 12,5 --- --- 15 29,4 

20 --- --- 4 100 9 60 3 21,4 --- --- --- --- 16 24,6 

21 --- --- 1 100 2 66,7 --- --- --- --- --- --- 3 9,4 

22 --- --- 1 100 3 30 2 16,7 --- --- --- --- 6 12,5 

23 --- --- 25 100 28 80 17 51,5 4 14,8 3 25 77 58,3 

24 --- --- 14 77,8 21 50 10 25,6 --- --- --- --- 45 37,8 

25 --- --- --- --- 2 66,7 2 25 2 25 --- --- 6 31,6 

26 --- --- 10 83,3 10 76,9 2 16,7 --- --- --- --- 22 40,7 

27 --- --- 3 75 6 75 --- --- 1 6,3 --- --- 10 27,8 

28 --- --- --- --- 6 75 --- --- 1 12,5 --- --- 7 41,2 

29 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 6,7 

30 --- --- 7 87,5 7 63,6 1 12,5 2 8,3 --- --- 17 33,3 

31 --- --- --- --- 1 50 --- --- --- --- --- --- 1 20 

32 1 100 3 75 3 60 1 12,5 --- --- --- --- 8 30,8 

33 --- --- 4 28,6 3 10 --- --- --- --- --- --- 7 6,8 

34 1 100 1 50 5 62,5 3 33,3 --- --- --- --- 10 35,7 

35 --- --- 3 100 1 14,3 --- --- 1 20 --- --- 5 29,4 

36 --- --- 4 80 9 81,8 7 41,2 1 6,3 --- --- 21 42,9 

37 --- --- 2 100 2 66,7 2 22,2 --- --- --- --- 6 27,3 

38 1 100 3 75 3 42,9 1 11,1 2 20 --- --- 10 32,3 

39 --- --- 2 100 9 64,3 1 10 1 5,3 --- --- 13 27,7 

40 --- --- 2 100 1 20 2 33,3 --- --- --- --- 5 20,8 


Note: Excluded babies died in Delivery Room and discharged before day 28. Analyzed population: Admitted babies 

discharged after day 28.

EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

41 --- --- 4 66,7 6 75 4 30,8 --- --- --- --- 14 33,3 

42 --- --- 1 100 4 100 8 57,1 1 14,3 --- --- 14 53,8 

43 --- --- --- --- 1 20 3 30 1 5 --- --- 5 14,3 

44 --- --- 2 33,3 1 14,3 --- --- --- --- --- --- 3 6,5 

45 --- --- 2 100 3 60 2 25 1 8,3 --- --- 8 29,6 

46 1 100 1 100 --- --- 3 60 --- --- --- --- 5 55,6 

47 --- --- 2 100 1 33,3 1 20 --- --- --- --- 4 21,1 

48 --- --- 1 100 2 50 1 25 4 22,2 --- --- 8 29,6 

49 --- --- 2 100 2 40 3 30 1 25 --- --- 8 38,1 

50 --- --- 1 100 7 87,5 4 57,1 1 20 --- --- 13 61,9 

51 1 100 8 100 14 73,7 7 22,6 1 4,5 --- --- 31 31,6 

52 2 100 16 100 27 71,1 6 18,2 4 10,3 --- --- 55 43 

53 --- --- 2 66,7 3 75 3 60 2 18,2 --- --- 10 43,5 

54 1 100 1 100 --- --- 1 100 3 75 --- --- 6 85,7 

55 --- --- 7 77,8 18 72 16 31,4 2 4,3 --- --- 43 32,6 

56 --- --- --- --- 1 33,3 1 16,7 --- --- --- --- 2 13,3 

57 --- --- 1 25 3 33,3 3 25 2 8,7 --- --- 9 18,8 

58 --- --- 1 50 5 45,5 2 11,1 2 9,1 --- --- 10 18,9 

59 --- --- 2 100 1 50 --- --- 1 16,7 --- --- 4 33,3 

60 --- --- 4 100 4 57,1 7 53,8 3 20 --- --- 18 46,2 

61 --- --- 5 100 8 88,9 3 25 3 23,1 --- --- 19 48,7 

62 1 100 1 100 1 25 2 25 --- --- --- --- 5 23,8 

63 --- --- 4 100 9 60 7 19,4 3 11,1 --- --- 23 28 

64 --- --- 1 100 2 50 4 40 1 6,7 --- --- 8 26,7 

65 --- --- 4 100 4 80 2 25 --- --- --- --- 10 35,7 

66 --- --- 2 100 21 95,5 10 50 5 29,4 --- --- 38 62,3 

67 --- --- 3 30 11 47,8 7 24,1 --- --- --- --- 21 22,6 

68 --- --- 4 100 7 63,6 6 33,3 2 14,3 --- --- 19 40,4 

69 --- --- 1 100 --- --- --- --- 1 12,5 --- --- 2 13,3 

70 --- --- 5 100 11 61,1 6 31,6 4 17,4 1 6,3 27 33,3 

71 --- --- 3 42,9 --- --- 1 20 1 20 --- --- 5 22,7 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 2 100 2 40 4 30,8 --- --- --- --- 8 36,4 

74 1 100 11 84,6 7 41,2 8 53,3 3 20 --- --- 30 42,9 

75 1 100 4 80 7 63,6 4 17,4 4 26,7 --- --- 20 29,4 

76 1 100 18 94,7 12 70,6 6 28,6 2 12,5 --- --- 39 45,3 

77 1 50 7 77,8 5 55,6 2 16,7 1 6,3 1 16,7 17 31,5 

78 --- --- 5 100 2 66,7 --- --- --- --- --- --- 7 18,4 

79 1 100 8 88,9 2 40 2 14,3 2 16,7 --- --- 15 28,8 

80 --- --- 2 66,7 9 90 3 60 2 18,2 --- --- 16 53,3 

81 1 100 3 75 9 69,2 --- --- 2 20 1 10 16 34 

82 1 100 4 100 7 77,8 6 60 4 28,6 2 18,2 24 49 

83 4 100 18 100 14 51,9 11 39,3 4 12,9 --- --- 51 39,5 

84 2 100 5 83,3 9 56,3 3 18,8 3 8,8 --- --- 22 29,7 

85 1 100 3 75 6 85,7 --- --- 3 25 --- --- 13 41,9 

86 --- --- 3 100 13 76,5 3 50 2 13,3 --- --- 21 44,7 




EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

87 --- --- --- --- 4 100 5 45,5 3 15 2 16,7 14 29,8 

88 1 100 13 100 11 91,7 9 47,4 4 19,0 2 25 40 54,1 

89 --- --- 1 100 2 100 5 41,7 --- --- --- --- 8 21,1 

90 --- --- 2 100 4 57,1 4 44,4 1 9,1 --- --- 11 29,7 

91 --- --- --- --- 4 80 4 44,4 1 9,1 1 16,7 10 32,3 

92 --- --- 18 90 25 83,3 22 73,3 6 22,2 --- --- 71 65,1 

93 --- --- 18 85,7 18 60 16 37,2 6 15 --- --- 58 36 

94 11 100 19 95 19 70,4 2 15,4 --- --- --- --- 51 56 

95 --- --- --- --- 7 77,8 1 33,3 3 27,3 4 80 15 53,6 

96 --- --- 2 100,0 9 56,3 5 41,7 1 6,7 1 9,1 18 32,1 

TOTAL 43 91,5 443 85,4 618 60,1 362 28,6 163 11,2 25 5,9 1654 34,9 




EuroNeoNet 


6.14.2 O 2 on day 28 Rate by Gestational Age. 

Table 6.14.2 shows the Oxygen on day 28 distribution according to gestational 


Supplemental Oxygen on day 28 Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- 1 100 --- --- --- --- --- --- --- --- 1 100 

3 1 100 4 80 1 100 --- --- --- --- --- --- 6 85,7 

4 --- --- 3 100 1 100 --- --- --- --- --- --- 4 100 

5 3 100 4 100 2 100 --- --- --- --- --- --- 9 100 

6 1 100 --- --- 2 100 --- --- --- --- --- --- 3 100 

8 --- --- --- --- --- --- 1 50 1 11,1 --- --- 2 15,4 

9 --- --- 1 50 3 75 4 57,1 3 50 --- --- 11 50 

10 1 100 5 100 3 100 9 75 2 11,1 --- --- 20 44,4 

11 --- --- 5 62,5 2 12,5 3 13,6 --- --- --- --- 10 15,4 

12 --- --- 13 92,9 46 85,2 35 36,5 11 11 3 8,6 108 36,1 

13 --- --- --- --- 1 100 1 14,3 --- --- --- --- 2 11,8 

14 --- --- 8 100 21 70 17 22,7 3 3,6 5 16,7 54 23,9 

15 --- --- 3 100 10 83,3 6 40 3 12,5 --- --- 22 31 

16 --- --- 1 100 2 50 --- --- --- --- --- --- 3 9,4 

17 --- --- 3 100 13 92,9 12 60 --- --- 1 11,1 29 42 

18 --- --- 4 100 6 75 4 28,6 3 17,6 --- --- 17 34 

19 --- --- 4 100 3 75 5 35,7 1 4,5 2 28,6 15 29,4 

20 --- --- 5 83,3 8 53,3 3 33,3 --- --- --- --- 16 24,6 

21 --- --- 1 100 2 66,7 --- --- --- --- --- --- 3 9,4 

22 --- --- 2 50 2 28,6 2 14,3 --- --- --- --- 6 12,5 

23 1 100 19 95 29 87,9 19 54,3 6 18,2 3 30 77 58,3 

24 --- --- 6 100 27 71,1 11 25 1 3,2 --- --- 45 37,8 

25 --- --- --- --- 1 100 5 45,5 --- --- --- --- 6 31,6 

26 1 100 4 80 11 78,6 5 41,7 1 6,7 --- --- 22 40,7 

27 --- --- 1 100 6 100 3 16,7 --- --- --- --- 10 27,8 

28 --- --- --- --- 3 60 1 25 2 33,3 1 50 7 41,2 

29 --- --- 1 100 --- --- --- --- --- --- --- --- 1 6,7 

30 --- --- 6 85,7 8 72,7 1 11,1 1 7,1 1 10 17 33,3 

31 --- --- --- --- 1 100 --- --- --- --- --- --- 1 20 

32 1 100 4 100 2 40 1 14,3 --- --- --- --- 8 30,8 

33 --- --- 5 38,5 2 8 --- --- --- --- --- --- 7 6,8 

34 --- --- 3 75 3 50 2 25 1 20 1 20 10 35,7 

35 --- --- 2 100 1 20 1 25 1 20 --- --- 5 29,4 

36 --- --- 5 100 5 71,4 7 50 4 30,8 --- --- 21 42,9 

37 --- --- 3 100 1 50 1 25 1 9,1 --- --- 6 27,3 

38 --- --- 2 66,7 4 100 4 40 --- --- --- --- 10 32,3 

39 --- --- --- --- 9 75 3 21,4 --- --- 1 9,1 13 27,7 

40 --- --- --- --- 2 100 3 37,5 --- --- --- --- 5 20,8 

41 --- --- 3 100,0 3 50 6 40 2 20 --- --- 14 33,3 

42 --- --- 1 100 6 85,7 6 75 1 20 --- --- 14 53,8 

43 --- --- 1 100 1 50 2 40 1 5,9 --- --- 5 14,3 

44 --- --- --- --- 3 42,9 --- --- --- --- --- --- 3 6,5 

45 --- --- 1 100 2 100 5 38,5 --- --- --- --- 8 29,6 




EuroNeoNet 


Supplemental Oxygen on day 28 Rate against Gestational Age by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

46 --- --- --- --- 1 100 3 60 1 33,3 --- --- 5 55,6 

47 --- --- 1 100 3 75 --- --- --- --- --- --- 4 21,1 

48 --- --- --- --- 4 100 4 40 --- --- --- --- 8 29,6 

49 --- --- --- --- 6 75 1 16,7 1 14,3 --- --- 8 38,1 

50 --- --- 3 100 4 100 5 71,4 1 20 --- --- 13 61,9 

51 1 50 12 92,3 12 75 6 27,3 --- --- --- --- 31 31,6 

52 --- --- 23 95,8 20 87 9 31 1 3 2 10,5 55 43 

53 --- --- 1 100 6 100 2 40 --- --- 1 33,3 10 43,5 

54 --- --- 1 100 1 100 --- --- 2 66,7 2 100 6 85,7 

55 --- --- 8 100 23 63,9 10 26,3 2 5,6 --- --- 43 32,6 

56 --- --- 1 50 --- --- --- --- 1 33,3 --- --- 2 13,3 

57 1 100 1 50 3 37,5 4 30,8 --- --- --- --- 9 18,8 

58 --- --- 3 100 3 42,9 3 30 1 5,6 --- --- 10 18,9 

59 --- --- 1 100 1 100 1 50 1 25 --- --- 4 33,3 

60 --- --- 4 100 5 100 5 62,5 4 26,7 --- --- 18 46,2 

61 --- --- 2 100 8 100 6 75 3 21,4 --- --- 19 48,7 

62 --- --- --- --- 5 71,4 --- --- --- --- --- --- 5 23,8 

63 --- --- 1 100 12 85,7 8 36,4 2 6,7 --- --- 23 28 

64 --- --- --- --- 5 71,4 3 42,9 --- --- --- --- 8 26,7 

65 --- --- 2 100 6 85,7 1 10 1 33,3 --- --- 10 35,7 

66 1 100 8 100 8 100 17 70,8 4 30,8 --- --- 38 62,3 

67 --- --- 7 63,6 9 50 4 11,4 1 5 --- --- 21 22,6 

68 --- --- 1 100 9 64,3 4 28,6 4 28,6 1 25 19 40,4 

69 --- --- --- --- 2 100 --- --- --- --- --- --- 2 13,3 

70 --- --- 7 87,5 10 71,4 8 40 2 6,5 --- --- 27 33,3 

71 --- --- 2 33,3 2 33,3 --- --- 1 14,3 --- --- 5 22,7 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- 2 33,3 5 62,5 1 14,3 --- --- 8 36,4 

74 --- --- 8 100 11 55 9 34,6 2 12,5 --- --- 30 42,9 

75 --- --- 4 100 8 61,5 6 30 2 8,3 --- --- 20 29,4 

76 --- --- 14 100 14 87,5 10 45,5 1 3,4 --- --- 39 45,3 

77 --- --- 8 88,9 6 66,7 2 11,1 1 7,1 --- --- 17 31,5 

78 --- --- --- --- 5 83,3 2 18,2 --- --- --- --- 7 18,4 

79 --- --- 6 85,7 3 42,9 6 40 --- --- --- --- 15 28,8 

80 --- --- 1 100 9 90 5 83,3 1 16,7 --- --- 16 53,3 

81 --- --- 1 100 9 100 6 33,3 --- --- --- --- 16 34 

82 --- --- 4 100 10 90,9 7 50 3 16,7 --- --- 24 49 

83 1 100 9 90 24 75 14 38,9 3 7 --- --- 51 39,5 

84 2 100 7 100 8 61,5 1 8,3 4 11,8 --- --- 22 29,7 

85 1 100 5 83,3 3 75 4 50 --- --- --- --- 13 41,9 

86 1 100 4 100 10 90,9 4 44,4 1 5,9 1 20 21 44,7 

87 --- --- --- --- 6 100 3 30 5 20 --- --- 14 29,8 

88 1 100 6 85,7 19 100 8 47,1 5 25 1 10 40 54,1 

89 --- --- 1 100 2 100 4 50 1 4,8 --- --- 8 21,1 

90 --- --- 2 100 8 88,9 1 14,3 --- --- --- --- 11 29,7 

91 --- --- 2 100 3 100 4 28,6 1 10 --- --- 10 32,3 

92 1 100 21 95,5 27 87,1 15 50,0 5 31,3 2 22,2 71 65,1 

93 2 100 15 93,8 23 79,3 15 37,5 2 3,6 1 5,3 58 36 

94 5 100 26 92,9 14 63,6 5 26,3 1 6,3 --- --- 51 56 

95 --- --- --- --- 2 100 7 77,8 6 54,5 --- --- 15 53,6 

96 --- --- 2 100 9 75 6 37,5 1 4,8 --- --- 18 32,1 

TOTAL 26 96,3 369 88,5 661 72,2 441 33,8 128 8,6 29 5 1654 34,9 




EuroNeoNet 


6.14.3 O 2 on day 28 Standardized Rate by Perinatal Risk Factors. 

Graph 6.14.3 corresponds to the 95% CI for the standardised Oxygen on day 28 adjusted rate. 

Graph 6.14.3 

The results for Units 1, 3, 4, 5, 6, 8, 11, 12, 13, 14, 16, 20, 21, 22, 29, 31, 33, 37, 40, 43, 44, 47, 55, 56, 57, 58, 62, 63, 67, 69, 70, 

71, 75, 78, 79, 81, 87, 88, 89, 90, 91 and 93 reached statistical significant relevance, being the Oxygen on day 28 rate for 

these Units significantly smaller than the one expected according to the standard’s population Oxygen on day 28 

distribution. On the other hand, Unit 66 had a bigger significant Oxygen on day 28 rate than the one expected according to 

the standard’s population Oxygen on day 28 distribution. 

Unit 2 didn’t register Oxygen on day 28. 




Note: Excluded babies died in Delivery Room and discharged before day 28. Analyzed population: Admitted babies discharged after day 28.

EuroNeoNet 


6.15 O 2 on week 36 Rate. 

Definition: if the infant was still in hospital and received any supplemental oxygen on the date 

when the infant was 36 weeks post-conceptional age. 

Note 1: if the infant was not alive in your hospital on the date at which the infant was 36 weeks 

adjusted gestational age or if the infant had a gestational age after rounding off to the nearest 

week, of 36 weeks or more at birth, the item is Not Applicable, so not listed in these results. 

Note 2: Excluded babies discharged before week 36 adjusted to gestational age. 

6.15.1 O 2 on week 36 Rate by Birth weight. 

The global Oxygen at week 36 adjusted to Gestational Age rate for 2010 cohort 

has been of 16.8%, with a variation of 1.3% and 51.2% within units. 

Oxygen at Week 36 Adjusted to Gestational Age Rate against Birth Weight by 

Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

8 --- --- --- --- --- --- 1 16,7 1 12,5 --- --- 2 11,8 

9 --- --- --- --- 1 50 2 100 2 22,2 --- --- 5 38,5 

10 1 100 3 100 1 20 --- --- 1 10 --- --- 6 17,6 

11 --- --- 4 50 --- --- --- --- --- --- --- --- 4 10,3 

12 1 100 16 50 9 17 8 14,3 5 6,8 --- --- 39 16,4 

13 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 7,1 

14 1 100 9 47,4 3 9,7 2 4,8 2 2,8 --- --- 17 10,1 

15 --- --- 2 40 1 6,7 --- --- --- --- --- --- 3 5,2 

16 --- --- 1 100 1 33,3 --- --- --- --- --- --- 2 6,5 

17 --- --- 1 12,5 4 40 1 10 1 4,8 --- --- 7 12,7 

18 --- --- --- --- 1 16,7 --- --- 1 6,7 2 40 4 9,1 

19 --- --- 4 66,7 --- --- 1 10 1 6,3 --- --- 6 13,3 

20 --- --- 2 50 3 21,4 1 7,7 --- --- --- --- 6 10,3 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- 1 100 1 11,1 --- --- --- --- --- --- 2 4,5 

23 --- --- 17 94,4 15 57,7 8 34,8 2 8,3 3 23,1 45 43,3 

24 --- --- 6 40 10 33,3 3 13,6 --- --- --- --- 19 23,8 

25 --- --- --- --- 1 33,3 1 14,3 1 16,7 --- --- 3 18,8 

26 --- --- 7 58,3 5 41,7 --- --- --- --- --- --- 12 26,7 

27 --- --- 3 75 1 16,7 --- --- --- --- --- --- 4 13,3 

28 --- --- --- --- 1 20 --- --- --- --- --- --- 1 6,7 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 5 62,5 4 40 1 14,3 2 8,7 --- --- 12 25 

31 --- --- --- --- 1 100 --- --- --- --- --- --- 1 16,7 

32 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 4,8 

33 --- --- 1 7,1 --- --- --- --- --- --- --- --- 1 1,3 

34 1 100 --- --- 1 14,3 2 25 --- --- --- --- 4 14,8 

35 --- --- --- --- --- --- --- --- 1 20 --- --- 1 6,7 

36 --- --- 1 50 4 40 3 21,4 --- --- --- --- 8 18,2 

37 --- --- 1 100 2 66,7 1 12,5 --- --- --- --- 4 19 

38 --- --- --- --- 1 14,3 1 11,1 --- --- --- --- 2 5,9 

39 --- --- 1 100 5 41,7 2 22,2 1 6,3 --- --- 9 23,7 

40 --- --- --- --- --- --- 2 33,3 --- --- --- --- 2 8,7 


Note: Excluded babies died in Delivery Room and discharged before week 36 adjusted for GA. Analyzed population: 

Admitted babies discharge after week 36 adjusted for GA.

EuroNeoNet 




Unit 

Code 


N % N % N % N % N % N % N % 

41 --- --- 2 40 3 37,5 4 40 --- --- --- --- 9 23,7 

42 --- --- 1 100 2 66,7 6 46,2 2 33,3 --- --- 11 47,8 

43 --- --- --- --- 1 20 2 20 --- --- --- --- 3 7,9 

44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

45 --- --- --- --- 2 66,7 1 14,3 1 11,1 --- --- 4 21,1 

46 1 100 1 100 --- --- 1 33,3 --- --- --- --- 3 42,9 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- 1 25 --- --- --- --- --- --- 1 4,8 

49 --- --- --- --- --- --- 1 14,3 --- --- --- --- 1 6,3 

50 --- --- --- --- 4 50 1 16,7 1 20 --- --- 6 30 

51 --- --- 4 50 6 33,3 1 3,8 --- --- --- --- 11 13,1 

52 1 100 11 78,6 11 31,4 2 8,7 1 3,3 --- --- 26 25,2 

53 --- --- --- --- 2 66,7 3 60 1 14,3 --- --- 6 33,3 

54 --- --- 1 100 --- --- --- --- 1 25 --- --- 2 28,6 

55 --- --- 3 37,5 7 50 6 17,6 2 6,3 --- --- 18 20,5 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 2,4 

58 --- --- 2 100 2 18,2 1 5,9 1 5,6 --- --- 6 12,5 

59 --- --- 2 100 --- --- --- --- --- --- --- --- 2 18,2 

60 --- --- 3 75 1 14,3 --- --- 2 15,4 --- --- 6 17,1 

61 --- --- 3 60 4 44,4 1 9,1 1 9,1 --- --- 9 25 

62 1 100 --- --- --- --- 1 14,3 --- --- --- --- 2 10,5 

63 --- --- 3 75 6 46,2 1 4,5 --- --- --- --- 10 14,3 

64 --- --- 1 100 --- --- 1 14,3 1 10 --- --- 3 14,3 

65 --- --- 1 25 --- --- --- --- --- --- --- --- 1 4,2 

66 --- --- 1 50 8 40 4 21,1 1 6,3 --- --- 14 24,6 

67 --- --- 1 11,1 6 30 1 3,7 --- --- --- --- 8 10,5 

68 --- --- 4 100 6 54,5 2 11,8 1 9,1 --- --- 13 30,2 

69 --- --- 1 100 --- --- --- --- --- --- --- --- 1 5,6 

70 --- --- 5 100 4 28,6 2 20 2 7,1 --- --- 13 19,7 

71 --- --- 1 20 --- --- --- --- 1 10 --- --- 2 9,5 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 2 100 2 40 1 9,1 --- --- --- --- 5 25 

74 --- --- 6 54,5 4 36,4 2 20 1 12,5 --- --- 13 27,1 

75 --- --- 2 66,7 5 45,5 1 4,5 --- --- --- --- 8 11,8 

76 --- --- 7 50 2 20 1 9,1 1 7,1 --- --- 11 19 

77 --- --- 1 12,5 1 12,5 --- --- --- --- --- --- 2 4,2 

78 --- --- 2 50 1 50 --- --- --- --- --- --- 3 9,7 

79 1 100 1 20 --- --- 1 7,1 2 14,3 --- --- 5 10,4 

80 --- --- 2 100 3 33,3 --- --- 2 14,3 --- --- 7 22,6 




EuroNeoNet 




Unit 

Code 


N % N % N % N % N % N % N % 

81 --- --- 1 25 1 9,1 --- --- 1 7,1 --- --- 3 7 

82 1 100 --- --- 3 42,9 1 11,1 2 14,3 2 22,2 9 20,9 

83 3 75 6 33,3 3 15 1 4,3 1 4,5 --- --- 14 14,4 

84 --- --- 1 16,7 --- --- --- --- 1 3,4 --- --- 2 3,2 

85 1 100 2 66,7 2 33,3 --- --- --- --- --- --- 5 17,9 

86 --- --- --- --- 3 17,6 1 16,7 2 13,3 --- --- 6 12,8 

87 --- --- --- --- 3 75 4 40 1 5,3 1 14,3 9 22,5 

88 --- --- 6 75 5 83,3 8 44,4 2 11,8 2 28,6 23 41,1 

89 --- --- 1 100 --- --- 1 11,1 --- --- --- --- 2 6,5 

90 --- --- --- --- 2 50 2 40 1 14,3 --- --- 5 26,3 

91 --- --- --- --- 1 25 3 42,9 1 10 --- --- 5 19,2 

92 --- --- 14 93,3 15 83,3 11 50 2 7,4 --- --- 42 51,2 

93 --- --- 8 44,4 4 21,1 1 5 1 9,1 --- --- 14 20 

94 2 25 4 66,7 2 12,5 --- --- --- --- --- --- 8 13,3 

95 --- --- --- --- 6 85,7 --- --- 2 28,6 2 40 10 45,5 

96 --- --- --- --- 1 10 2 16,7 --- --- 1 11,1 4 8,5 

TOTAL 15 46,9 203 48,8 222 27,8 123 12,6 64 4,9 13 4,8 640 16,8 




EuroNeoNet 


6.15.2 O 2 on week 36 Rate by Gestational Age. 

Table 6.15.2 shows the Oxygen on week 36 distribution according to 


Unit 

Code 

Oxygen at week 36 Adjusted to Gestational Age Rate against Gestational Age by 



N % N % N % N % N % N % N % 

8 --- --- --- --- --- --- 1 50 1 11,1 --- --- 2 11,8 

9 --- --- 1 50 --- --- 2 66,7 2 50 --- --- 5 38,5 

10 --- --- 4 100 --- --- 2 22,2 --- --- --- --- 6 17,6 

11 --- --- 2 66,7 1 33,3 1 11,1 --- --- --- --- 4 10,3 

12 --- --- 5 45,5 17 42,5 11 18,6 3 4,5 3 4,9 39 16,4 

13 --- --- --- --- --- --- 1 25 --- --- --- --- 1 7,1 

14 --- --- 2 40 6 28,6 4 8,5 1 2,2 4 8 17 10,1 

15 --- --- 1 50 1 11,1 1 9,1 --- --- --- --- 3 5,2 

16 --- --- 1 100 1 33,3 --- --- --- --- --- --- 2 6,5 

17 --- --- --- --- 4 40 2 15,4 --- --- 1 7,7 7 12,7 

18 --- --- 1 25 --- --- 1 10 2 14,3 --- --- 4 9,1 

19 --- --- 2 50 --- --- 2 18,2 1 5,6 1 11,1 6 13,3 

20 --- --- 3 50 3 21,4 --- --- --- --- --- --- 6 10,3 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- 1 33,3 1 14,3 --- --- --- --- --- --- 2 4,5 

23 1 100 10 90,9 16 59,3 10 43,5 4 12,9 4 36,4 45 43,3 

24 --- --- 1 33,3 16 55,2 1 3,8 1 4,5 --- --- 19 23,8 

25 --- --- --- --- 1 100 2 22,2 --- --- --- --- 3 18,8 

26 1 100 2 40 7 53,8 1 11,1 1 11,1 --- --- 12 26,7 

27 --- --- --- --- 3 60 1 7,1 --- --- --- --- 4 13,3 

28 --- --- --- --- --- --- --- --- 1 20 --- --- 1 6,7 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 4 57,1 5 55,6 --- --- --- --- 3 21,4 12 25 

31 --- --- --- --- 1 100 --- --- --- --- --- --- 1 16,7 

32 --- --- 1 50 --- --- --- --- --- --- --- --- 1 4,8 

33 --- --- 1 8,3 --- --- --- --- --- --- --- --- 1 1,3 

34 --- --- 1 33,3 1 16,7 1 16,7 --- --- 1 14,3 4 14,8 

35 --- --- --- --- --- --- --- --- 1 20 --- --- 1 6,7 

36 --- --- 2 66,7 1 20 1 12,5 4 33,3 --- --- 8 18,2 

37 --- --- 1 100 1 50 1 33,3 1 10 --- --- 4 19 

38 --- --- --- --- 1 33,3 1 10 --- --- --- --- 2 5,9 

39 --- --- --- --- 5 55,6 1 12,5 1 12,5 2 15,4 9 23,7 

40 --- --- --- --- --- --- 2 25 --- --- --- --- 2 8,7 

41 --- --- --- --- 1 20 6 60 2 22,2 --- --- 9 23,7 

42 --- --- --- --- 5 83,3 4 57,1 --- --- 2 33,3 11 47,8 

43 --- --- 1 100 1 100 --- --- 1 7,1 --- --- 3 7,9 

44 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

45 --- --- --- --- --- --- 4 50 --- --- --- --- 4 21,1 

46 --- --- --- --- 1 100 1 50 1 33,3 --- --- 3 42,9 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- 1 25 --- --- --- --- --- --- 1 4,8 

49 --- --- --- --- --- --- 1 16,7 --- --- --- --- 1 6,3 

50 --- --- 1 33,3 1 25 3 60 1 20 --- --- 6 30 




EuroNeoNet 


Unit 

Code 

N % N % N % N % N % N % N % 

51 1 100 6 50 4 26,7 --- --- --- --- --- --- 11 13,1 

52 --- --- 14 70 9 42,9 1 5,6 --- --- 2 8,3 26 25,2 

53 --- --- --- --- 4 80 1 25 --- --- 1 20 6 33,3 

54 --- --- --- --- 1 100 --- --- --- --- 1 50 2 28,6 

55 --- --- 3 60 9 45 5 25 --- --- 1 4,5 18 20,5 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- --- --- --- --- --- --- 1 10 --- --- 1 2,4 

58 --- --- 2 66,7 2 28,6 --- --- 2 15,4 --- --- 6 12,5 

59 --- --- --- --- 1 100 1 50 --- --- --- --- 2 18,2 

60 --- --- 3 75 --- --- 1 20 2 14,3 --- --- 6 17,1 

61 --- --- 2 100 4 50 3 42,9 --- --- --- --- 9 25 

62 --- --- --- --- 2 50 --- --- --- --- --- --- 2 10,5 

63 --- --- --- --- 5 38,5 3 25 2 11,1 --- --- 10 14,3 

64 --- --- --- --- 1 50 2 66,7 --- --- --- --- 3 14,3 

65 --- --- 1 50 --- --- --- --- --- --- --- --- 1 4,2 

66 --- --- 5 71,4 1 14,3 8 34,8 --- --- --- --- 14 24,6 

67 --- --- 3 33,3 3 18,8 1 4,3 1 6,7 --- --- 8 10,5 

68 --- --- 1 100 6 42,9 1 8,3 4 36,4 1 20 13 30,2 

69 --- --- --- --- 1 50 --- --- --- --- --- --- 1 5,6 

70 --- --- 6 75 5 50 2 22,2 --- --- --- --- 13 19,7 

71 --- --- --- --- 1 25 --- --- 1 12,5 --- --- 2 9,5 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- 2 40 2 28,6 1 14,3 --- --- 5 25 

74 --- --- 4 50 7 58,3 1 7,1 1 7,1 --- --- 13 27,1 

75 --- --- 2 66,7 4 36,4 1 5,6 1 4,3 --- --- 8 11,8 

76 --- --- 4 50 3 27,3 2 20 --- --- 2 22,2 11 19 

77 --- --- --- --- 2 25 --- --- --- --- --- --- 2 4,2 

78 --- --- --- --- 2 40 1 10 --- --- --- --- 3 9,7 

79 --- --- 1 50 1 16,7 2 13,3 --- --- 1 11,1 5 10,4 

80 --- --- 1 100 4 44,4 --- --- 1 16,7 1 10 7 22,6 

81 --- --- --- --- 2 28,6 1 8,3 --- --- --- --- 3 7 

82 --- --- --- --- 3 37,5 3 23,1 3 21,4 --- --- 9 20,9 

83 1 100 5 55,6 4 16,7 3 11,1 1 3,6 --- --- 14 14,4 

84 --- --- 1 14,3 --- --- --- --- 1 3,8 --- --- 2 3,2 

85 1 100 2 40 1 33,3 1 14,3 --- --- --- --- 5 17,9 

86 1 100 1 25 1 9,1 1 11,1 1 5,9 1 20 6 12,8 

87 --- --- --- --- 4 80 1 11,1 4 22,2 --- --- 9 22,5 

88 --- --- 2 100 11 78,6 4 36,4 5 35,7 1 6,7 23 41,1 

89 --- --- 1 100 --- --- --- --- 1 5,6 --- --- 2 6,5 

90 --- --- 1 100 3 60 1 50 --- --- --- --- 5 26,3 

91 --- --- 1 50 1 33,3 2 22,2 1 12,5 --- --- 5 19,2 

92 --- --- 13 100 13 65 10 50 4 33,3 2 11,8 42 51,2 

93 1 50 6 50 4 30,8 2 20 --- --- 1 6,3 14 20 

94 1 100 3 18,8 3 33,3 1 7,7 --- --- --- --- 8 13,3 

95 --- --- --- --- 2 100 5 83,3 3 37,5 --- --- 10 45,5 

96 --- --- --- --- --- --- 3 20 1 5,6 --- --- 4 8,5 

TOTAL 8 61,5 142 47,8 238 35,3 145 16,6 71 6,4 36 4,3 640 16,8 

. 

Oxygen at week 36 Adjusted to Gestational Age Rate against Gestational Age by 






EuroNeoNet 


6.15.3 O 2 on week 36 Standardized Rate by Perinatal Risk Factors. 

Graph 5.16.1 corresponds to the 95% CI for the standardised Oxygen on week 36 rate adjusted. 

Graph 6.15.3 

The results for Units 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 24, 32, 33, 34, 35, 38, 43, 48, 49, 51, 55, 57, 62, 63, 65, 67, 69, 70, 

71, 74, 75, 76, 77, 78, 79, 81, 83, 84, 89, 90, 91, 93, 94 and 96 reached statistical significant relevance, being the Oxygen on 

week 36 rate for these Units significantly smaller than the one expected according to the standard’s population Oxygen on 

week 36 distribution. On the other hand none Unit had a bigger significant Oxygen on week 36 rate than the one expected 

according to the standard’s population Oxygen on week 36 distribution. 

Units 1, 2, 3, 4, 5, 6, 21, 29, 44, 47 and 56 didn’t register Oxygen on week 36. 

Note 1: Standardization items: Birth weight Z-Score by gestational age , 1-min Apgar Score, 5- 

min apgar Score, Mode of Delivery and Major Birth Defects. 



Note: Excluded babies died in Delivery Room and discharged before week 36 adjusted for GA. Analyzed population: Admitted babies discharge after week 36 adjusted for GA.

EuroNeoNet 


6.16 Late Bacterial Sepsis Rate. 

Definition: if a bacterial pathogen from the list in Appendix I (ENS Manual) is recovered from a 

blood and/or cerebrospinal fluid culture obtained after day 3 of life. 

Note 1: The date of birth counts as day 1 regardless of the time of birth. 

6.16.1 Late Bacterial Sepsis Rate by Birth Weight. 

The global Late Sepsis rate for 2010 cohort has been of 23.3%, with a variation 

of 5.7% and 70.4% within units. 

Late Bacterial Sepsis Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- 3 37,5 3 20 4 19 2 6,5 2 10,5 14 14,7 

2 --- --- 1 100 1 33,3 --- --- 1 14,3 2 22,2 5 20 

3 1 100 5 31,3 10 43,5 5 13,5 --- --- 1 2,4 22 14,2 

4 1 33,3 4 50 2 25 1 6,3 --- --- --- --- 8 11,4 

5 1 33,3 10 47,6 15 50 6 18,8 1 2,6 3 7,1 36 21,6 

6 2 22,2 7 43,8 3 8,8 4 14,8 1 2,3 1 2,4 18 10,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- 2 20 4 26,7 2 28,6 8 22,2 

10 1 100 2 28,6 1 14,3 3 18,8 2 14,3 1 6,3 10 16,4 

11 --- --- 5 38,5 11 44 10 30,3 6 12,8 2 7,7 34 23,4 

12 --- --- 25 44,6 28 34,6 28 28,3 21 13,5 7 8 109 22,7 

13 --- --- --- --- --- --- 1 50 1 8,3 --- --- 2 8 

14 3 100 16 48,5 21 44,7 17 25,4 25 20,3 7 13,7 89 27,5 

15 --- --- 2 33,3 4 18,2 1 14,3 1 2,8 --- --- 8 9,6 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- 2 22,2 1 7,1 2 7,7 2 7,1 1 7,7 8 8,9 

18 --- --- 2 50 6 85,7 9 39,1 7 31,8 3 23,1 27 39,1 

19 1 100 5 62,5 1 16,7 3 20 1 5,3 1 5,6 12 17,9 

20 --- --- --- --- 8 44,4 --- --- --- --- 1 6,7 9 11,4 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- 1 20 4 36,4 3 25 --- --- 1 6,3 9 14,1 

23 1 100 22 71 21 41,2 12 21,1 8 16,7 --- --- 64 30 

24 --- --- 13 56,5 25 48,1 10 21,3 1 2,6 --- --- 49 30,4 

25 --- --- --- --- 2 66,7 4 40 1 8,3 --- --- 7 28 

26 --- --- 8 42,1 5 35,7 2 14,3 1 4,5 --- --- 16 23,2 

27 --- --- 4 66,7 5 41,7 2 22,2 3 14,3 --- --- 14 29,2 

28 --- --- --- --- 5 62,5 2 100 1 11,1 --- --- 8 42,1 

29 1 100 --- --- 2 66,7 1 33,3 --- --- --- --- 4 23,5 

30 --- --- 5 50 5 27,8 2 18,2 --- --- --- --- 12 17,1 

31 --- --- --- --- 1 33,3 1 50 1 16,7 --- --- 3 27,3 

32 1 50 3 50 2 28,6 1 12,5 4 44,4 --- --- 11 34,4 

33 1 25 7 41,2 9 29 2 6,1 1 2 --- --- 20 14,7 

34 1 100 3 50 7 58,3 6 60 2 15,4 --- --- 19 45,2 

35 1 100 2 33,3 1 12,5 --- --- 2 28,6 --- --- 6 24 

36 --- --- 4 50 7 58,3 11 61,1 6 19,4 --- --- 28 40,6 

37 --- --- 2 66,7 3 100 3 27,3 9 42,9 --- --- 17 43,6 

38 1 100 1 20 5 62,5 3 30 6 33,3 --- --- 16 38,1 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

39 --- --- 4 80 12 66,7 7 58,3 5 22,7 1 50 29 49,2 

40 --- --- 1 25 --- --- 3 37,5 1 7,7 --- --- 5 16,1 

41 --- --- 8 72,7 7 58,3 9 60 14 66,7 1 100 39 65 

42 --- --- 1 50 4 66,7 9 50 --- --- --- --- 14 41,2 

43 --- --- 1 50 2 22,2 2 18,2 --- --- --- --- 5 9,6 

44 --- --- 2 33,3 4 44,4 2 16,7 1 4 --- --- 9 17,3 

45 --- --- 2 40 1 14,3 4 33,3 6 37,5 --- --- 13 32,5 

46 --- --- 1 50 --- --- --- --- --- --- --- --- 1 9,1 

47 --- --- 1 33,3 --- --- 1 16,7 3 20 --- --- 5 17,9 

48 --- --- 1 100 3 60 2 50 7 36,8 --- --- 13 44,8 

49 --- --- 2 66,7 3 60 3 30 2 50 --- --- 10 45,5 

50 --- --- 1 25 7 87,5 6 85,7 5 62,5 --- --- 19 70,4 

51 --- --- 5 45,5 14 60,9 1 2,9 3 10,7 3 13,6 26 21,5 

52 1 50 14 73,7 19 46,3 6 17,1 5 10,4 --- --- 45 31 

53 --- --- 5 83,3 1 16,7 2 40 --- --- --- --- 8 26,7 

54 1 100 3 100 --- --- 1 50 4 57,1 --- --- 9 69,2 

55 --- --- 12 60 24 66,7 24 40 9 13 --- --- 69 37,3 

56 --- --- --- --- 4 100 4 66,7 1 14,3 --- --- 9 52,9 

57 --- --- 4 50 5 45,5 4 33,3 4 17,4 --- --- 17 31,5 

58 --- --- --- --- 7 53,8 1 5,6 3 11,5 --- --- 11 18 

59 --- --- 1 50 2 100 1 33,3 1 14,3 --- --- 5 35,7 

60 --- --- 4 100 5 71,4 7 53,8 6 37,5 --- --- 22 55 

61 --- --- 6 66,7 5 55,6 6 42,9 2 15,4 --- --- 19 42,2 

62 1 100 4 57,1 3 50 2 22,2 --- --- --- --- 10 30,3 

63 --- --- 5 62,5 18 75 16 40 11 22,4 --- --- 50 41,3 

64 --- --- 1 100 4 80 4 33,3 4 17,4 --- --- 13 31,7 

65 --- --- 4 66,7 6 75 2 20 4 28,6 --- --- 16 42,1 

66 1 100 2 50 14 60,9 10 50 7 41,2 --- --- 34 52,3 

67 --- --- 9 50 14 46,7 11 34,4 9 20,5 --- --- 43 34,4 

68 --- --- 2 18,2 4 33,3 3 16,7 5 33,3 --- --- 14 25 

69 --- --- 3 100 --- --- 1 16,7 --- --- --- --- 4 18,2 

70 --- --- 2 33,3 13 52 1 5 2 5,3 --- --- 18 15,5 

71 --- --- 3 37,5 4 66,7 1 16,7 1 8,3 --- --- 9 28,1 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- 2 66,7 2 40 1 7,7 --- --- --- --- 5 20 

74 1 50 3 17,6 3 12,5 3 13 2 7,7 2 6,9 14 11,6 

75 1 100 4 33,3 4 33,3 4 14,3 --- --- --- --- 13 13 

76 --- --- 6 28,6 4 14,3 4 13,3 --- --- --- --- 14 9,6 

77 1 33,3 2 22,2 --- --- --- --- --- --- 1 12,5 4 5,9 

78 1 100 1 16,7 --- --- --- --- 1 7,7 --- --- 3 6,3 

79 1 100 4 36,4 --- --- --- --- --- --- --- --- 5 6,2 

80 --- --- --- --- 5 45,5 --- --- 2 12,5 1 33,3 8 20,5 



EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

81 1 50 5 50 5 23,8 --- --- 2 4,8 1 4,3 14 11,7 

82 --- --- 2 40 2 18,2 --- --- 2 10,5 2 13,3 8 12,7 

83 1 14,3 12 48 7 24,1 6 18,8 5 11,6 1 2,6 32 18,4 

84 --- --- 1 11,1 3 16,7 1 6,3 --- --- --- --- 5 5,7 

85 --- --- --- --- 4 50 2 40 1 7,7 --- --- 7 20,6 

86 --- --- --- --- 7 38,9 2 33,3 --- --- --- --- 9 18 

87 --- --- --- --- 2 50 4 21,1 5 22,7 2 12,5 13 21,3 

88 1 100 14 58,3 15 65,2 16 48,5 7 18,9 6 24 59 41,3 

89 --- --- 1 50 2 66,7 5 41,7 2 16,7 4 25 14 31,1 

90 --- --- 1 33,3 2 22,2 2 18,2 --- --- --- --- 5 7,1 

91 --- --- 1 33,3 2 40 4 44,4 2 12,5 3 27,3 12 27,3 

92 --- --- 9 25,7 6 14,3 3 5,9 5 8,5 --- --- 23 12,1 

93 --- --- 5 13,5 15 42,9 12 25,5 21 35 10 19,6 63 25,8 

94 --- --- 5 19,2 4 10,3 1 3,3 4 16 --- --- 14 9,6 

95 --- --- 1 10 9 75 3 42,9 10 58,8 6 60 29 50,9 

96 --- --- 1 50 8 47,1 1 7,7 1 4,5 1 6,3 12 17,1 

TOTAL 29 27,9 358 42,1 544 39,1 392 23,1 318 13,3 80 8,6 1721 23,3 



EuroNeoNet 


6.16.2 Late Bacterial Sepsis Rate by Gestational Age. 

Table 6.16.2 shows the Late Bacterial Sepsis distribution according to 


Unit 

Code 

Late Sepsis Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 4 40 5 29,4 3 13,6 2 6,1 --- --- 14 14,7 

2 --- --- 1 50 --- --- --- --- 4 28,6 --- --- 5 20 

3 3 60 10 71,4 4 21,1 5 15,2 --- --- --- --- 22 14,2 

4 1 33,3 5 62,5 1 9,1 1 7,1 --- --- --- --- 8 11,4 

5 4 44,4 5 45,5 16 40 5 17,9 6 8,8 --- --- 36 21,6 

6 2 25 6 31,6 6 20,7 3 7,7 1 1,6 --- --- 18 10,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- 1 16,7 3 33,3 3 23,1 1 20 8 22,2 

10 1 100 2 28,6 1 25 4 28,6 1 3,6 1 14,3 10 16,4 

11 --- --- 5 38,5 9 47,4 9 24,3 8 15,4 3 12,5 34 23,4 

12 --- --- 11 29,7 34 50,7 33 28,4 22 12,5 9 10,7 109 22,7 

13 --- --- --- --- --- --- 1 14,3 1 11,1 --- --- 2 8 

14 --- --- 7 43,8 17 48,6 34 42 21 16,7 10 15,4 89 27,5 

15 --- --- 1 25 4 26,7 2 11,8 --- --- 1 4,5 8 9,6 

16 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

17 --- --- 1 33,3 3 18,8 1 4,3 2 6,5 1 5,9 8 8,9 

18 --- --- 4 100 7 63,6 7 43,8 5 19,2 4 33,3 27 39,1 

19 --- --- 5 62,5 3 75 2 12,5 1 3,6 1 9,1 12 17,9 

20 --- --- 3 37,5 5 29,4 --- --- 1 3,2 --- --- 9 11,4 

21 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

22 --- --- 2 28,6 1 11,1 4 26,7 2 8,7 --- --- 9 14,1 

23 1 100 16 55,2 24 60 13 21 8 12,5 2 11,8 64 30 

24 --- --- 5 50 26 56,5 13 22,8 5 10,6 --- --- 49 30,4 

25 --- --- --- --- 1 50 5 41,7 1 25 --- --- 7 28 

26 1 50 4 40 7 46,7 2 14,3 1 5,3 1 11,1 16 23,2 

27 --- --- 2 100 6 50 4 20 2 25 --- --- 14 29,2 

28 --- --- --- --- 4 80 1 25 1 16,7 2 50 8 42,1 

29 --- --- --- --- 1 50 2 33,3 1 25 --- --- 4 23,5 

30 --- --- 5 45,5 7 43,8 --- --- --- --- --- --- 12 17,1 

31 --- --- --- --- 1 100 --- --- 2 66,7 --- --- 3 27,3 

32 1 100 4 57,1 1 14,3 1 14,3 --- --- 4 80 11 34,4 

33 --- --- 8 50 7 25 2 8,3 3 6,3 --- --- 20 14,7 

34 --- --- 3 50 8 66,7 4 50 3 42,9 1 11,1 19 45,2 

35 --- --- 2 66,7 1 14,3 1 20 2 33,3 --- --- 6 24 

36 --- --- 5 62,5 4 50 6 37,5 10 52,6 3 16,7 28 40,6 

37 --- --- 3 100 1 25 3 42,9 8 53,3 2 20 17 43,6 

38 --- --- 1 33,3 5 71,4 6 54,5 4 36,4 --- --- 16 38,1 

39 1 50 1 50 12 80 7 43,8 2 20 6 42,9 29 49,2 

40 --- --- --- --- 1 33,3 2 20 1 10 1 14,3 5 16,1 

41 --- --- 5 71,4 6 66,7 12 70,6 7 58,3 9 60 39 65 

42 --- --- 1 50 7 77,8 4 50 1 11,1 1 16,7 14 41,2 

43 --- --- 2 33,3 --- --- 2 33,3 1 5,9 --- --- 5 9,6 

44 --- --- 1 25 3 37,5 4 33,3 --- --- 1 5,3 9 17,3 



EuroNeoNet 


Unit 

Code 

Late Sepsis Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

45 --- --- 1 33,3 1 33,3 8 47,1 1 14,3 2 20 13 32,5 

46 1 100 --- --- --- --- --- --- --- --- --- --- 1 9,1 

47 --- --- 1 50 1 20 1 14,3 2 25 --- --- 5 17,9 

48 --- --- --- --- 4 80 7 70 2 28,6 --- --- 13 44,8 

49 --- --- --- --- 5 62,5 1 16,7 4 57,1 --- --- 10 45,5 

50 --- --- 3 75 4 66,7 6 85,7 5 71,4 1 33,3 19 70,4 

51 1 25 9 60 8 44,4 2 7,1 4 10,3 2 11,8 26 21,5 

52 1 50 21 77,8 11 47,8 6 19,4 3 8,3 3 11,5 45 31 

53 --- --- 3 100 3 37,5 1 20 1 11,1 --- --- 8 26,7 

54 --- --- 3 100 1 100 --- --- 3 60 2 50 9 69,2 

55 1 50 9 64,3 28 54,9 17 38,6 9 21,4 5 15,6 69 37,3 

56 --- --- 3 100 2 100 2 40 2 66,7 --- --- 9 52,9 

57 2 66,7 4 80 1 11,1 3 23,1 4 40 3 21,4 17 31,5 

58 --- --- 2 40 3 37,5 3 27,3 1 5 2 12,5 11 18 

59 --- --- 1 100 --- --- 1 33,3 2 50 1 20 5 35,7 

60 --- --- 4 100 5 100 6 75 7 46,7 --- --- 22 55 

61 --- --- 2 40 5 62,5 6 66,7 5 31,3 1 14,3 19 42,2 

62 --- --- 2 40 6 66,7 --- --- 2 25 --- --- 10 30,3 

63 --- --- 3 42,9 17 70,8 13 52 12 34,3 5 16,7 50 41,3 

64 --- --- 1 100 4 57,1 5 55,6 2 16,7 1 8,3 13 31,7 

65 --- --- 3 60 6 66,7 5 41,7 --- --- 2 25 16 42,1 

66 1 50 6 66,7 7 70 12 50 6 46,2 2 28,6 34 52,3 

67 --- --- 11 61,1 9 39,1 10 25 7 25,9 6 35,3 43 34,4 

68 --- --- 1 20 5 29,4 4 28,6 4 28,6 --- --- 14 25 

69 1 100 --- --- 2 50 1 33,3 --- --- --- --- 4 18,2 

70 --- --- 6 50 9 52,9 1 4,3 1 2,3 1 5 18 15,5 

71 --- --- 4 57,1 3 50 1 25 1 12,5 --- --- 9 28,1 

72 --- --- --- --- --- --- 1 100 --- --- --- --- 1 50 

73 --- --- --- --- 1 16,7 4 50 --- --- --- --- 5 20 

74 --- --- 3 23,1 5 20,8 1 2,9 5 10,2 --- --- 14 11,6 

75 --- --- 4 33,3 6 46,2 3 13,6 --- --- --- --- 13 13 

76 --- --- 3 15,8 7 29,2 1 3,8 3 5,4 --- --- 14 9,6 

77 --- --- --- --- 3 33,3 1 5 --- --- --- --- 4 5,9 

78 --- --- 1 50 1 16,7 1 6,3 --- --- --- --- 3 6,3 

79 --- --- 2 25 3 27,3 --- --- --- --- --- --- 5 6,2 

80 --- --- --- --- 3 30 3 42,9 2 22,2 --- --- 8 20,5 

81 --- --- 3 37,5 6 33,3 5 16,7 --- --- --- --- 14 11,7 

82 --- --- 1 14,3 3 27,3 --- --- 4 15,4 --- --- 8 12,7 

83 2 22,2 7 58,3 9 26,5 7 16,7 4 6,1 3 27,3 32 18,4 

84 --- --- 3 27,3 1 6,7 --- --- 1 2,9 --- --- 5 5,7 

85 --- --- 1 16,7 2 40 1 12,5 3 25 --- --- 7 20,6 

86 --- --- 1 14,3 5 45,5 2 22,2 1 5,9 --- --- 9 18 

87 --- --- --- --- 3 37,5 5 41,7 5 15,6 --- --- 13 21,3 

88 3 100 13 65 18 64,3 11 37,9 11 26,2 3 14,3 59 41,3 

89 --- --- 2 100 2 100 3 30 7 30,4 --- --- 14 31,1 

90 --- --- --- --- 5 45,5 --- --- --- --- --- --- 5 7,1 

91 --- --- 1 33,3 4 80 4 28,6 3 17,6 --- --- 12 27,3 

92 3 60 8 24,2 5 11,4 3 6,3 4 10,8 --- --- 23 12,1 

93 --- --- 7 26,9 7 22,6 13 27,7 20 23 16 50 63 25,8 

94 2 40 3 9,4 5 15,6 3 8,6 1 3,2 --- --- 14 9,6 

95 --- --- 2 22,2 2 100 9 69,2 10 55,6 6 54,5 29 50,9 

96 --- --- 2 100 4 30,8 4 23,5 2 6,5 --- --- 12 17,1 

TOTAL 33 30 310 42,9 510 40,8 418 24,3 319 13,1 131 11,5 1721 23,3 



EuroNeoNet 


6.16.3 Late Bacterial Sepsis Standardized Rate by Perinatal Risk Factors. 

Graph 6.16.3 corresponds to the 95% CI for the standardised late bacterial sepsis adjusted rate. 

Graph 6.16.3 

The results for Units 1, 3, 4, 6, 13, 15, 17, 20, 33, 43,70, 74, 75, 76, 77, 78, 79, 81, 82, 83,84, 90, 92 and 94 reached statistical 

significant relevance, being the Late Onset Sepsis (LOS) rate for these Units significantly smaller than the one expected 

according to the standard’s population LOS distribution. On the other hand Units 18, 34, 36, 37, 39, 41, 50 ,55, 60, 66, 67, 88 

and 95 had a bigger significant LOS rate than the one expected according to the standard’s population LOS distribution. 

Units 8, 16 and 21 didn’t register late bacterial sepsis. 

Note 1: Standardization items: Birth weight Z-Score by gestational age and 1-min Apgar Score 




EuroNeoNet 


6.17 Steroids for CLD Rate. 

Definition: if corticosteroids were used after birth to treat or prevent BPD-CLD. 

6.17.1 Steroids for CLD Rate by Birth Weight. 

The global Steroids for CLD rate for 2010 cohort has been of 6.2%, with a 


Unit 

Code 

Steroids for CLD Rate against Birth Weight by Participating Unit 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 --- --- 3 37,5 4 26,7 3 14,3 1 3,2 1 5,3 12 12,6 

2 --- --- 1 100 1 33,3 --- --- --- --- --- --- 2 8 

3 --- --- 8 50 5 21,7 2 5,4 1 2,8 1 2,4 17 11 

4 1 33,3 7 87,5 4 50 2 12,5 1 4,8 --- --- 15 21,4 

5 1 33,3 3 14,3 3 10 1 3,1 --- --- --- --- 8 4,8 

6 3 33,3 7 43,8 6 17,6 2 7,4 2 4,5 --- --- 20 11,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 16,7 2 22,2 --- --- 3 13,6 

9 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 2,8 

10 1 100 3 42,9 2 28,6 --- --- --- --- --- --- 6 9,8 

11 1 100 6 46,2 3 12 2 6,1 --- --- --- --- 12 8,3 

12 1 33,3 12 21,4 5 6,2 5 5,1 3 1,9 1 1,1 27 5,6 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 1 33,3 4 12,1 1 2,1 3 4,5 --- --- --- --- 9 2,8 

15 --- --- 2 33,3 2 9,1 --- --- --- --- --- --- 4 4,8 

16 --- --- 1 50 --- --- --- --- 1 5,3 --- --- 2 5 

17 --- --- 4 44,4 3 21,4 --- --- 1 3,6 --- --- 8 8,9 

18 --- --- 3 75 4 57,1 3 13 4 18,2 2 15,4 16 23,2 

19 --- --- 3 37,5 --- --- 1 6,7 1 5,3 --- --- 5 7,5 

20 --- --- 1 20 2 11,1 --- --- --- --- --- --- 3 3,8 

21 --- --- 1 33,3 1 20 1 9,1 --- --- --- --- 3 7,3 

22 --- --- 1 20 4 36,4 --- --- --- --- 1 6,3 6 9,4 

23 --- --- 6 19,4 2 3,9 1 1,8 --- --- --- --- 9 4,2 

24 --- --- 3 11,5 5 9,3 --- --- --- --- --- --- 8 4,7 

25 --- --- --- --- --- --- 1 10 --- --- --- --- 1 4 

26 --- --- 7 36,8 4 28,6 --- --- --- --- --- --- 11 15,9 

27 --- --- 3 50 3 27,3 --- --- --- --- --- --- 6 12,8 

28 --- --- --- --- 1 12,5 --- --- 1 11,1 --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 3,1 

33 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

34 1 100 --- --- 2 16,7 --- --- --- --- --- --- 3 7,1 

35 --- --- 3 50 1 12,5 --- --- --- --- --- --- 4 16 

36 --- --- 1 12,5 --- --- --- --- --- --- --- --- 1 1,4 

37 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,6 

38 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

39 --- --- --- --- 4 22,2 --- --- --- --- --- --- 4 6,8 

40 --- --- 2 50 --- --- 4 50 --- --- 1 100 7 23,3 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- 1 50 2 33,3 3 16,7 --- --- --- --- 6 17,6 



EuroNeoNet 


Steroids for CLD Rate against Birth Weight by Participating Unit 

Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

43 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,9 

44 --- --- 3 50 1 11,1 --- --- 1 4 --- --- 5 9,6 

45 --- --- 1 20 1 14,3 --- --- --- --- --- --- 2 5 

46 1 100 1 50 --- --- --- --- --- --- --- --- 2 18,2 

47 --- --- 1 33,3 1 25 1 16,7 --- --- --- --- 3 10,7 

48 --- --- --- --- 1 20 --- --- --- --- --- --- 1 3,4 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 3,7 

51 --- --- 1 9,1 3 13,6 --- --- --- --- --- --- 4 3,3 

52 2 66,7 8 42,1 8 19 --- --- --- --- --- --- 18 12 

53 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,3 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 2 10 7 19,4 2 3,3 --- --- --- --- 11 5,9 

56 --- --- --- --- 1 25 --- --- --- --- --- --- 1 5,9 

57 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

58 --- --- 1 25 --- --- --- --- --- --- --- --- 1 1,6 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- 3 75 1 14,3 --- --- --- --- --- --- 4 10 

61 --- --- 1 11,1 2 22,2 --- --- --- --- --- --- 3 6,7 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- 3 37,5 5 20,8 1 2,5 --- --- --- --- 9 7,4 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- 2 33,3 2 25 --- --- --- --- --- --- 4 10,5 

66 --- --- 1 20 2 8 --- --- --- --- --- --- 3 4,3 

67 --- --- --- --- --- --- 1 3,1 --- --- --- --- 1 0,8 

68 --- --- 3 27,3 --- --- 2 11,1 --- --- --- --- 5 8,9 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 16,7 --- --- --- --- 1 2,6 1 3,7 3 2,6 

71 --- --- 2 25 --- --- --- --- --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 1 33,3 --- --- 2 15,4 --- --- --- --- 3 12 

83 1 14,3 5 20 2 6,9 1 3,1 --- --- 1 2,6 10 5,7 

84 --- --- 4 44,4 5 27,8 --- --- 1 2,4 --- --- 10 11,4 

85 1 100 2 50 3 37,5 --- --- 1 7,7 --- --- 7 20,6 

86 --- --- 1 20 4 22,2 1 16,7 1 6,7 --- --- 7 14 

87 --- --- --- --- 1 25 --- --- --- --- --- --- 1 1,5 

88 1 50 2 7,4 1 3,8 --- --- --- --- --- --- 4 2,6 

89 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,2 

90 --- --- 1 25 1 11,1 --- --- --- --- --- --- 2 2,8 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- 4 11,4 3 7,1 2 3,9 --- --- --- --- 9 4,7 

93 --- --- 5 13,5 3 8,6 3 6,4 --- --- --- --- 11 4,5 

94 --- --- 1 3,8 --- --- 1 3,3 --- --- --- --- 2 1,4 

95 --- --- --- --- 6 50 --- --- 1 5,9 4 36,4 11 19 

96 --- --- 1 50 1 5,9 1 7,7 --- --- 1 6,3 4 5,8 

TOTAL 16 17,2 159 20,6 143 11,3 53 3,4 25 1,1 14 1,8 410 6,2 



EuroNeoNet 


6.17.2 Steroids for CLD Rate by Gestational Age. 

Table 6.17.2 shows the Steroids for CLD distribution according to gestational 


Unit 

Code 

Steroids for CLD Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 6 60 5 29,4 --- --- 1 3 --- --- 12 12,6 

2 --- --- 2 100 --- --- --- --- --- --- --- --- 2 8 

3 2 40 8 57,1 2 10,5 3 9,1 1 1,4 1 7,1 17 11 

4 1 33,3 7 87,5 4 36,4 2 14,3 1 3,7 --- --- 15 21,4 

5 1 11,1 2 18,2 5 12,5 --- --- --- --- --- --- 8 4,8 

6 2 25 8 42,1 7 24,1 3 7,7 --- --- --- --- 20 11,6 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- 1 50 2 15,4 --- --- 3 13,6 

9 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 2,8 

10 1 100 4 57,1 1 25 --- --- --- --- --- --- 6 9,8 

11 --- --- 6 46,2 2 10,5 3 8,1 1 1,9 --- --- 12 8,3 

12 --- --- 4 10,8 9 13,4 9 7,8 4 2,3 1 1,2 27 5,6 

13 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

14 --- --- 3 18,8 4 11,4 1 1,2 --- --- 1 1,5 9 2,8 

15 --- --- 1 25 3 20 --- --- --- --- --- --- 4 4,8 

16 --- --- 1 100 --- --- 1 25 --- --- --- --- 2 5 

17 --- --- 2 66,7 5 31,3 1 4,3 --- --- --- --- 8 8,9 

18 --- --- 4 100 3 27,3 2 12,5 7 26,9 --- --- 16 23,2 

19 --- --- 2 25 --- --- 1 6,3 1 3,6 1 9,1 5 7,5 

20 --- --- 1 12,5 2 11,8 --- --- --- --- --- --- 3 3,8 

21 --- --- --- --- 2 40 1 16,7 --- --- --- --- 3 7,3 

22 --- --- 1 14,3 3 33,3 1 6,7 1 4,3 --- --- 6 9,4 

23 --- --- 4 13,8 4 10 1 1,6 --- --- --- --- 9 4,2 

24 --- --- 5 35,7 3 6,3 --- --- --- --- --- --- 8 4,7 

25 --- --- --- --- --- --- 1 8,3 --- --- --- --- 1 4 

26 --- --- 3 30 6 40 1 7,1 1 5,3 --- --- 11 15,9 

27 --- --- 1 50 4 36,4 1 5 --- --- --- --- 6 12,8 

28 --- --- --- --- 1 20 --- --- 1 16,7 --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 1 100 --- --- --- --- --- --- --- --- --- --- 1 3,1 

33 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

34 --- --- 3 50 --- --- --- --- --- --- --- --- 3 7,1 

35 --- --- 2 66,7 2 28,6 --- --- --- --- --- --- 4 16 

36 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 1,4 

37 --- --- --- --- --- --- --- --- 1 6,7 --- --- 1 2,6 

38 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

39 --- --- --- --- 3 20 1 6,3 --- --- --- --- 4 6,8 

40 --- --- --- --- 2 66,7 3 30 1 11,1 1 14,3 7 23,3 

41 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

42 --- --- --- --- 4 44,4 1 12,5 1 11,1 --- --- 6 17,6 

43 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 1,9 

44 --- --- 3 75 1 12,5 --- --- 1 11,1 --- --- 5 9,6 

45 --- --- 1 33,3 --- --- 1 5,9 --- --- --- --- 2 5 

46 --- --- --- --- 1 100 --- --- 1 33,3 --- --- 2 18,2 



EuroNeoNet 


Unit 

Code 

Steroids for CLD Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

47 --- --- 1 50 2 40 --- --- --- --- --- --- 3 10,7 

48 --- --- --- --- 1 20 --- --- --- --- --- --- 1 3,4 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,7 

51 1 25 2 14,3 1 5,6 --- --- --- --- --- --- 4 3,3 

52 --- --- 12 44,4 6 25 --- --- --- --- --- --- 18 12 

53 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 3,3 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- 3 21,4 8 15,7 --- --- --- --- --- --- 11 5,9 

56 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 5,9 

57 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

58 --- --- 1 20 --- --- --- --- --- --- --- --- 1 1,6 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- 4 100 --- --- --- --- --- --- --- --- 4 10 

61 --- --- 1 20 2 25 --- --- --- --- --- --- 3 6,7 

62 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

63 --- --- 1 14,3 5 20,8 3 12 --- --- --- --- 9 7,4 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- 2 40 2 22,2 --- --- --- --- --- --- 4 10,5 

66 --- --- 2 18,2 1 9,1 --- --- --- --- --- --- 3 4,3 

67 --- --- --- --- 1 4,3 --- --- --- --- --- --- 1 0,8 

68 --- --- 1 20 4 23,5 --- --- --- --- --- --- 5 8,9 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- 1 8,3 --- --- --- --- 1 2,3 1 5 3 2,6 

71 --- --- 1 14,3 1 16,7 --- --- --- --- --- --- 2 6,3 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- 2 25 1 14,3 --- --- 3 12 

83 1 11,1 3 25 5 14,7 --- --- 1 1,5 --- --- 10 5,7 

84 2 100 5 45,5 2 13,3 1 7,7 --- --- --- --- 10 11,4 

85 1 100 2 33,3 2 40 2 25 --- --- --- --- 7 20,6 

86 1 100 3 42,9 2 18,2 --- --- --- --- 1 20 7 14 

87 --- --- --- --- 1 10 --- --- --- --- --- --- 1 1,5 

88 --- --- 1 4,3 2 6,7 1 3,2 --- --- --- --- 4 2,6 

89 --- --- --- --- --- --- 1 10 --- --- --- --- 1 2,2 

90 --- --- --- --- 2 18,2 --- --- --- --- --- --- 2 2,8 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- 4 12,1 2 4,5 2 4,2 --- --- 1 4,3 9 4,7 

93 1 4,8 5 19,2 3 9,7 2 4,3 --- --- --- --- 11 4,5 

94 --- --- 1 3,1 --- --- 1 2,9 --- --- --- --- 2 1,4 

95 --- --- --- --- 2 100 5 38,5 4 21,1 --- --- 11 19 

96 --- --- 1 50 --- --- 2 12,5 1 3,2 --- --- 4 5,8 

TOTAL 15 12,9 143 21,8 148 13,1 61 4 35 1,6 8 0,8 410 6,2 



EuroNeoNet 


6.17.3 Steroids for CLD Standardized Rate by Perinatal Risk Factors. 

Graph 6.17.3, corresponds to the 95% CI for the standardised Steroids for CLD rate adjusted. 

Graph 6.17.3 

The results for Units 14, 36, 58, 67, 79, 87, 88 and 94 reached statistical significant relevance, being the Steroids for CLD 

rate for these Units significantly smaller than the one expected according to the standard’s population Steroids for CLD 

distribution. On the other hand Units 4, 6, 18, 52 and 95 had bigger significant Steroids for CLD rate than the one expected 

according to the standard’s population LOS distribution. 

Units 13, 29, 30, 31, 33, 38, 41, 49, 54, 57, 59, 62, 64, 69 and 91 didn’t register Steroids for CLD. 

Units 74, 75, 76, 77, 78, 79, 80, 81 and 82 don’t record Steroids for CLD. 





EuroNeoNet 


6.18 Cystic PVL Rate. 

Definition: If CYSTIC PVL, NON-CYSTIC PVL OR BOTH were diagnosed, please check the 

type as diagnosed by cranial ultrasound or other imaging technique. 

Note 1: To be considered cystic PVL there must be multiple small periventricular cysts 

identified. Periventricular echogenicity without cysts should not be coded as cystic PVL. A 

porencephalic cyst in the area of previously identified intraparenchymal hemorrhage should not 

be coded as cystic PVL. 

6.18.1 Cystic PVL Rate by Birth Weight. 

The global Cystic PVL rate for 2010 cohort has been of 4.4%, with a variation of 

0.9% and 100% within units. 

PVL Rate against Birth Weight by Participating Unit 

Unit 

Code 


N % N % N % N % N % N % N % 

1 --- --- 1 12,5 --- --- 2 9,5 1 3,2 1 5,3 5 5,3 

2 --- --- 1 100 --- --- --- --- 2 28,6 --- --- 3 12 

3 --- --- 1 6,3 5 21,7 2 5,4 5 13,9 4 9,5 17 11 

4 --- --- 2 25 1 12,5 2 12,5 3 14,3 1 7,1 9 12,9 

5 1 33,3 2 9,5 5 16,7 5 15,6 5 12,8 5 11,9 23 13,8 

6 1 11,1 2 12,5 1 2,9 1 3,7 --- --- --- --- 5 2,9 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- --- --- 1 11,1 1 6,7 --- --- 2 6,1 

10 --- --- --- --- 1 14,3 1 6,3 1 7,1 --- --- 3 5 

11 --- --- --- --- 1 4 1 3,2 --- --- --- --- 2 1,4 

12 --- --- 2 3,7 4 5,3 2 2,1 3 2,2 2 2,5 13 2,9 

13 --- --- --- --- 1 25 1 50 1 8,3 1 25 4 17,4 

14 --- --- 3 9,4 --- --- 2 3,1 1 0,9 1 2,1 7 2,3 

15 --- --- --- --- 1 5 --- --- 1 2,8 --- --- 2 2,5 

16 --- --- --- --- --- --- --- --- --- --- 1 9,1 1 2,5 

17 --- --- --- --- --- --- 1 3,8 --- --- 1 7,7 2 2,2 

18 --- --- --- --- --- --- 4 17,4 1 4,5 1 7,7 6 8,7 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- --- --- 2 11,1 --- --- 3 12,5 --- --- 5 6,3 

21 --- --- --- --- --- --- 2 18,2 --- --- --- --- 2 5 

22 --- --- --- --- --- --- --- --- 1 5,3 --- --- 1 1,6 

23 --- --- 3 9,7 2 3,9 4 7,1 1 2,2 --- --- 10 4,9 

24 --- --- --- --- 2 3,6 2 4,2 --- --- --- --- 4 2,4 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

28 --- --- --- --- 1 12,5 --- --- 1 11,1 --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- --- --- 1 5 --- --- 1 3 --- --- 4 5,4 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- --- --- --- --- 1 12,5 --- --- --- --- 1 3,1 

33 --- --- 1 5,6 --- --- 1 2,9 --- --- --- --- 2 1,4 

34 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 2,4 


Note: Excluded babies died in Delivery Room and babies with no cranial ultrasound or other technique done to diagnose 

PVL. Analyzed population: Admitted babies with a cranial ultrasound or other technique done to diagnose PVL done.

EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- --- --- 1 8,3 1 5,6 1 3,2 --- --- 3 4,3 

37 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,9 

38 --- --- --- --- --- --- --- --- 1 5,6 --- --- 1 2,4 

39 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

40 --- --- --- --- --- --- 1 12,5 --- --- --- --- 1 3,2 

41 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 1,7 

42 --- --- 1 50 1 25 2 11,8 1 12,5 --- --- 5 16,1 

43 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,9 

44 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,9 

45 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 --- --- --- --- 1 4,5 --- --- 3 10,7 --- --- 4 3,4 

52 --- --- 1 5,3 3 7,1 1 2,9 1 2 --- --- 6 4,1 

53 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,3 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- --- --- --- --- 3 5,1 1 1,5 --- --- 4 2,2 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- 1 14,3 1 10 --- --- 1 4,3 --- --- 3 5,8 

58 --- --- --- --- 1 7,7 --- --- 1 3,8 --- --- 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- 1 25 --- --- --- --- --- --- --- --- 1 2,5 

61 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

62 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 3,2 

63 --- --- --- --- 1 4,5 --- --- --- --- --- --- 1 0,9 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- 2 25 --- --- --- --- --- --- 2 5,3 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- --- --- 4 13,3 2 6,3 1 2,3 --- --- 7 5,6 

68 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 1,9 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- --- --- 1 4,8 --- --- 1 2,7 1 3,7 3 2,8 

71 --- --- --- --- 1 16,7 --- --- --- --- --- --- 1 3,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- --- --- 2 8,3 1 4,3 4 15,4 3 10,3 10 8,3 

75 --- --- --- --- --- --- --- --- 2 7,4 --- --- 2 2 

76 --- --- 3 14,3 2 7,1 3 10 --- --- 1 3,3 9 6,2 

77 1 33,3 --- --- 1 9,1 --- --- --- --- --- --- 2 2,9 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 1,2 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 




EuroNeoNet 



Unit 

Code 


N % N % N % N % N % N % N % 

81 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

82 --- --- 1 20 --- --- 1 8,3 1 5,3 --- --- 3 4,8 

83 --- --- --- --- --- --- 3 9,4 --- --- --- --- 3 1,8 

84 --- --- --- --- 2 11,1 3 18,8 2 4,8 --- --- 7 8 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- 1 5,6 1 16,7 --- --- --- --- 2 4,1 

87 --- --- --- --- 1 25 --- --- --- --- --- --- 1 1,6 

88 --- --- 1 3,8 --- --- 1 3,1 --- --- --- --- 2 1,5 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- --- --- 3 7,5 1 2,4 3 7,7 --- --- 7 4,6 

93 --- --- 9 29 6 17,6 12 26,1 7 12,5 10 20,4 44 20,4 

94 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

95 --- --- --- --- 2 33,3 --- --- 1 25 --- --- 3 18,8 

96 --- --- --- --- --- --- --- --- 2 9,1 --- --- 2 2,9 

TOTAL 3 3,8 39 5,2 73 5,8 71 4,6 66 3,1 33 4,5 285 4,4 




EuroNeoNet 


6.18.2 Cystic PVL Rate by Gestational Age. 

Table 6.18.2 shows the Cystic PVL distribution according to gestational age for 

each Unit. 

Unit 

Code 

PVL Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 --- --- 1 10 --- --- 1 4,5 3 9,1 --- --- 5 5,3 

2 --- --- 1 50 --- --- --- --- 1 7,1 1 20 3 12 

3 --- --- 2 14,3 2 10,5 3 9,1 8 11,4 2 14,3 17 11 

4 --- --- 2 25 1 9,1 4 28,6 1 3,7 1 14,3 9 12,9 

5 1 11,1 1 9,1 7 17,5 5 17,9 8 11,8 1 9,1 23 13,8 

6 --- --- 1 5,3 4 13,8 --- --- --- --- --- --- 5 2,9 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

9 --- --- --- --- 1 20 1 11,1 --- --- --- --- 2 6,1 

10 --- --- 1 16,7 --- --- 1 7,1 1 3,6 --- --- 3 5 

11 --- --- 1 7,7 1 5,3 --- --- --- --- --- --- 2 1,4 

12 --- --- 1 2,9 4 6,6 4 3,6 4 2,5 --- --- 13 2,9 

13 --- --- --- --- --- --- 2 28,6 2 25 --- --- 4 17,4 

14 --- --- 1 6,3 2 5,9 1 1,3 2 1,7 1 1,6 7 2,3 

15 --- --- --- --- --- --- --- --- 1 4 1 4,5 2 2,5 

16 --- --- --- --- --- --- --- --- 1 5,6 --- --- 1 2,5 

17 --- --- --- --- --- --- 1 4,3 --- --- 1 5,9 2 2,2 

18 --- --- --- --- 2 18,2 3 18,8 1 3,8 --- --- 6 8,7 

19 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

20 --- --- 2 25 1 5,9 --- --- 1 3,2 1 7,7 5 6,3 

21 --- --- --- --- --- --- --- --- 2 9,5 --- --- 2 5 

22 --- --- --- --- --- --- --- --- 1 4,3 --- --- 1 1,6 

23 1 100 1 3,4 4 10 2 3,3 --- --- 2 14,3 10 4,9 

24 --- --- --- --- 1 2,1 1 1,7 2 4,3 --- --- 4 2,4 

25 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

26 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

27 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

28 --- --- --- --- 1 20 --- --- 1 16,7 --- --- 2 10,5 

29 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

30 --- --- 1 8,3 2 12,5 1 10 --- --- --- --- 4 5,4 

31 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

32 --- --- --- --- --- --- --- --- 1 20 --- --- 1 3,1 

33 --- --- --- --- --- --- 2 8,3 --- --- --- --- 2 1,4 

34 --- --- --- --- 1 8,3 --- --- --- --- --- --- 1 2,4 

35 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

36 --- --- 1 12,5 --- --- --- --- 1 5,3 1 5,6 3 4,3 

37 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 2,9 

38 --- --- --- --- --- --- 1 9,1 --- --- --- --- 1 2,4 

39 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

40 --- --- --- --- --- --- --- --- 1 10 --- --- 1 3,2 

41 --- --- --- --- --- --- 1 5,9 --- --- --- --- 1 1,7 

42 --- --- --- --- 3 37,5 1 12,5 --- --- 1 16,7 5 16,1 

43 --- --- 1 16,7 --- --- --- --- --- --- --- --- 1 1,9 

44 --- --- 1 25 --- --- --- --- --- --- --- --- 1 1,9 

45 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

46 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 




EuroNeoNet 


Unit 

Code 

PVL Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

47 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

50 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

51 --- --- --- --- 1 5,6 1 3,6 1 2,6 1 5,9 4 3,4 

52 --- --- 3 11,1 1 4,2 1 3,1 1 2,8 --- --- 6 4,1 

53 --- --- --- --- 1 12,5 --- --- --- --- --- --- 1 3,3 

54 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

55 --- --- --- --- 1 2 2 4,5 1 2,4 --- --- 4 2,2 

56 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

57 --- --- 1 20 --- --- 2 15,4 --- --- --- --- 3 5,8 

58 --- --- 1 20 --- --- 1 9,1 --- --- --- --- 2 3,3 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- 1 25 --- --- --- --- --- --- --- --- 1 2,5 

61 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

62 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 3,2 

63 --- --- --- --- 1 4,5 --- --- --- --- --- --- 1 0,9 

64 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

65 --- --- --- --- 2 22,2 --- --- --- --- --- --- 2 5,3 

66 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

67 --- --- 2 11,1 3 13 1 2,5 1 3,7 --- --- 7 5,6 

68 --- --- --- --- 1 6,3 --- --- --- --- --- --- 1 1,9 

69 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

70 --- --- --- --- 1 7,1 1 4,5 1 2,3 --- --- 3 2,8 

71 --- --- 1 14,3 --- --- --- --- --- --- --- --- 1 3,1 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

74 --- --- --- --- 1 4,2 4 11,4 5 10,2 --- --- 10 8,3 

75 --- --- --- --- --- --- --- --- 1 2,6 1 6,7 2 2 

76 --- --- 2 10,5 2 8,3 4 15,4 1 1,8 --- --- 9 6,2 

77 --- --- --- --- 2 22,2 --- --- --- --- --- --- 2 2,9 

78 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

79 --- --- --- --- 1 9,1 --- --- --- --- --- --- 1 1,2 

80 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

81 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

82 --- --- --- --- 1 9,1 1 6,7 1 3,8 --- --- 3 4,8 

83 --- --- --- --- --- --- 2 4,8 1 1,6 --- --- 3 1,8 

84 --- --- --- --- 4 26,7 3 23,1 --- --- --- --- 7 8 

85 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

86 --- --- --- --- 2 18,2 --- --- --- --- --- --- 2 4,1 

87 --- --- --- --- 1 11,1 --- --- --- --- --- --- 1 1,6 

88 --- --- 1 4,3 --- --- 1 3,4 --- --- --- --- 2 1,5 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

91 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

92 --- --- 1 3,3 3 7,7 2 4,3 1 4,5 --- --- 7 4,6 

93 1 16,7 6 26,1 10 33,3 6 13,3 18 21,4 3 10,7 44 20,4 

94 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

95 --- --- --- --- 1 100 1 20 1 20 --- --- 3 18,8 

96 --- --- --- --- --- --- 1 5,9 1 3,2 --- --- 2 2,9 

TOTAL 3 4,7 38 5,9 79 7,1 69 4,4 78 3,7 18 1,8 285 4,4 




EuroNeoNet 


6.18.3 Cystic PVL Standardized Rate by Perinatal Risk Factors. 

Graph 6.18.3, corresponds to the 95% CI for the standardised Cystic PVL adjusted rate. 

3 

Graph 6.18.3 

Results for Units 11, 12, 14, 22, 24, 33, 41, 55, 63 ,70 ,75, 79, 83, 87 and 88 reached statistical significant relevance, being 

the Cystic PVL rate for these Units significantly smaller than the one expected according to the standard’s population. On 

the other hand Units 3, 5 and 93 had a bigger significant cystic PVL rate. 

Units 8, 19, 25, 26, 27, 29, 31, 35, 39, 45, 46, 47, 48, 49, 50, 54, 56, 59, 61, 64, 66, 69, 73, 78, 80, 81, 85, 89, 90, 91 and 94 didn’t 

register cystic PVL. 




Note: Excluded babies died in Delivery Room and babies with no cranial ultrasound or other technique done to diagnose PVL. Analyzed population: Admitted babies with a cranial ultrasound or other 

technique done to diagnose PVL done.

EuroNeoNet 


6.19 Mortality Rate. 

Definition: if the infant died on or before his/her first birthday at your hospital prior to being 

discharge home or transferred and if the infant died in the delivery room (if your Unit has one). 

6.19.1 Mortality Rate by Birth Weight. 

The global Mortality rate for 2010 cohort has been of 10.3%, with a variation of 

2.2% and 39.7% within units. 

Mortality Rate against Birth Weight by Participating Unit 

Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

1 1 100 2 25 1 6,7 --- --- --- --- 1 5,3 5 5,3 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 1 100 8 50 2 8,7 3 8,1 --- --- --- --- 14 9 

4 2 66,7 4 50 --- --- 1 6,3 --- --- --- --- 7 10 

5 --- --- 7 33,3 1 3,3 1 3,1 --- --- 1 2,4 10 6 

6 6 66,7 5 31,3 4 11,8 1 3,7 1 2,3 1 2,4 18 10,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- --- --- 1 20 1 4,5 

9 1 100 --- --- --- --- 1 10 --- --- --- --- 2 5,6 

10 --- --- 4 57,1 --- --- --- --- 1 7,1 --- --- 5 8,2 

11 --- --- 2 15,4 1 4 1 3 4 8,5 --- --- 8 5,5 

12 1 33,3 17 30,4 15 18,5 2 2 7 4,5 1 1,1 43 8,9 

13 --- --- --- --- 2 40 --- --- --- --- --- --- 2 8 

14 2 66,7 8 24,2 2 4,3 1 1,5 3 2,4 1 2 17 5,2 

15 1 100 --- --- 3 13,6 1 14,3 1 2,8 --- --- 6 7,2 

16 --- --- 1 50 --- --- --- --- --- --- --- --- 1 2,5 

17 --- --- 1 11,1 --- --- 1 3,8 --- --- --- --- 2 2,2 

18 --- --- 1 25 --- --- 2 8,7 --- --- --- --- 3 4,3 

19 --- --- 2 25 2 33,3 --- --- --- --- --- --- 4 6 

20 --- --- 1 20 3 16,7 --- --- 1 4,2 --- --- 5 6,3 

21 --- --- 2 66,7 2 40 1 9,1 --- --- --- --- 5 12,2 

22 --- --- 4 80 1 9,1 --- --- 1 5,3 --- --- 6 9,4 

23 1 100 10 32,3 8 15,7 3 5,3 1 2,1 --- --- 23 10,7 

24 --- --- 10 38,5 10 17,5 4 8,2 3 7,3 --- --- 27 15,6 

25 --- --- --- --- --- --- 1 10 --- --- --- --- 1 4 

26 --- --- 8 42,1 1 7,1 1 7,1 --- --- --- --- 10 14,5 

27 --- --- 1 16,7 3 25 1 11,1 --- --- --- --- 5 10,4 

28 --- --- --- --- 2 25 1 50 --- --- --- --- 3 15,8 

29 1 100 --- --- --- --- --- --- --- --- --- --- 1 5,9 

30 --- --- 2 20 6 30 1 9,1 6 18,2 --- --- 15 20,3 

31 --- --- --- --- 1 33,3 --- --- --- --- --- --- 1 9,1 

32 1 50 3 50 2 28,6 1 12,5 --- --- --- --- 7 21,9 

33 2 50 4 22,2 1 3,2 3 8,8 2 3,8 --- --- 12 8,6 

34 --- --- 4 66,7 5 41,7 1 10 --- --- --- --- 10 23,8 

35 1 100 3 50 1 12,5 --- --- --- --- --- --- 5 20 

36 --- --- 5 62,5 1 8,3 2 11,1 2 6,5 --- --- 10 14,5 

37 --- --- 1 33,3 --- --- --- --- 2 9,5 --- --- 3 7,7 

38 1 100 1 20 1 12,5 2 20 --- --- --- --- 5 11,9 

39 --- --- 4 80 4 22,2 3 25 1 4,5 --- --- 12 20,3 

40 --- --- 2 50 --- --- 2 25 --- --- --- --- 4 12,9 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

41 --- --- 5 45,5 4 33,3 --- --- 1 4,8 --- --- 10 16,7 

42 --- --- --- --- 2 33,3 1 5,6 --- --- --- --- 3 8,8 

43 --- --- 1 50 4 44,4 --- --- 1 3,3 --- --- 6 11,5 

44 --- --- --- --- 2 22,2 --- --- --- --- --- --- 2 3,8 

45 --- --- 4 80 2 28,6 2 16,7 1 6,3 --- --- 9 22,5 

46 --- --- 1 50 --- --- --- --- --- --- --- --- 1 9,1 

47 --- --- 1 33,3 1 25 --- --- --- --- --- --- 2 7,1 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

49 --- --- 2 66,7 1 20 --- --- --- --- --- --- 3 13,6 

50 --- --- 3 75 --- --- --- --- 2 25 --- --- 5 18,5 

51 2 100 3 27,3 3 13 2 5,7 2 7,1 --- --- 12 9,9 

52 2 66,7 5 26,3 7 16,7 5 13,5 3 6,1 --- --- 22 14,7 

53 --- --- 2 33,3 1 16,7 --- --- 1 7,7 --- --- 4 13,3 

54 1 100 2 66,7 --- --- --- --- 1 14,3 --- --- 4 30,8 

55 --- --- 11 55 12 33,3 6 10 --- --- --- --- 29 15,7 

56 --- --- --- --- 1 25 --- --- --- --- --- --- 1 5,9 

57 --- --- 5 62,5 3 27,3 --- --- --- --- --- --- 8 14,8 

58 --- --- 2 50 2 15,4 --- --- 1 3,8 --- --- 5 8,2 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

61 --- --- 3 33,3 --- --- --- --- --- --- --- --- 3 6,7 

62 --- --- 7 100 2 33,3 2 22,2 --- --- --- --- 11 33,3 

63 --- --- 4 50 10 41,7 3 7,5 4 8,2 --- --- 21 17,4 

64 --- --- --- --- 1 20 1 8,3 --- --- --- --- 2 4,9 

65 --- --- 2 33,3 3 37,5 1 10 --- --- --- --- 6 15,8 

66 1 100 3 60 3 12 1 4,8 --- --- --- --- 8 11,6 

67 --- --- 8 44,4 9 30 2 6,3 --- --- --- --- 19 15,2 

68 --- --- 7 63,6 1 8,3 --- --- --- --- --- --- 8 14,3 

69 --- --- 2 66,7 1 100 --- --- --- --- --- --- 3 13,6 

70 --- --- 1 16,7 10 40 --- --- --- --- 1 3,7 12 10,3 

71 --- --- 2 25 3 50 --- --- --- --- --- --- 5 15,6 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 1 100 1 33,3 --- --- --- --- --- --- --- --- 2 8 

74 1 50 4 23,5 3 12,5 --- --- --- --- 1 3,4 9 7,4 

75 --- --- 7 58,3 2 16,7 1 3,6 --- --- 2 10 12 12 

76 2 50 --- --- 1 3,6 1 3,3 1 3 --- --- 5 3,4 

77 2 66,7 --- --- 1 9,1 --- --- 1 4,2 --- --- 4 5,9 

78 1 100 1 16,7 --- --- 2 14,3 --- --- --- --- 4 8,3 

79 1 100 2 18,2 2 25 --- --- 1 3,8 --- --- 6 7,4 

80 --- --- --- --- 1 9,1 --- --- --- --- 1 33,3 2 5,1 



EuroNeoNet 



Unit 

Code 

< 501 gr. 501 - 750 gr. 751 - 1000 gr. 1001 - 1250 gr. 

1251 - 1500 gr. > 1500 gr. 

TOTAL 

N % N % N % N % N % N % N % 

81 1 50 5 50 3 14,3 3 13,6 --- --- --- --- 12 10 

82 --- --- 1 20 2 18,2 --- --- --- --- 1 6,7 4 6,3 

83 3 42,9 7 28 2 6,9 1 3,1 3 7 --- --- 16 9,2 

84 1 33,3 3 33,3 2 11,1 1 6,3 2 4,8 --- --- 9 10,2 

85 --- --- 1 25 2 25 --- --- --- --- --- --- 3 8,8 

86 --- --- 2 40 1 5,6 --- --- --- --- --- --- 3 6 

87 2 100 2 66,7 --- --- 2 10 --- --- --- --- 6 8,8 

88 1 50 10 37 8 30,8 3 8,6 1 2,6 2 7,7 25 16,1 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- 1 25 --- --- --- --- 1 4 --- --- 2 2,8 

91 --- --- 4 80 --- --- --- --- 1 6,3 --- --- 5 10,6 

92 1 100 17 48,6 8 19 6 11,8 2 3,4 --- --- 34 17,9 

93 9 64,3 12 31,6 3 8,6 2 4,3 2 3,3 4 7,8 32 13,1 

94 --- --- 1 3,8 2 5,1 1 3,3 --- --- --- --- 4 2,7 

95 1 100 9 90 5 41,7 3 42,9 1 5,9 4 36,4 23 39,7 

96 --- --- --- --- 1 5,9 --- --- 1 4,5 --- --- 2 2,9 

TOTAL 55 50,9 303 35 222 15,8 94 5,5 70 2,9 22 2,3 766 10,3 



EuroNeoNet 


6.19.2 Mortality Rate by Gestational Age. 

Unit 

Code 

Mortality Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

1 2 100 2 20 --- --- --- --- 1 3 --- --- 5 5,3 

2 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

3 5 100 4 28,6 4 21,1 --- --- --- --- 1 7,1 14 9 

4 2 66,7 4 50 1 9,1 --- --- --- --- --- --- 7 10 

5 3 33,3 4 36,4 2 5 1 3,6 --- --- --- --- 10 6 

6 6 75 7 36,8 1 3,4 3 7,7 --- --- 1 6,7 18 10,5 

7 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

8 --- --- --- --- --- --- --- --- 1 7,7 --- --- 1 4,5 

9 1 100 --- --- 1 16,7 --- --- --- --- --- --- 2 5,6 

10 1 100 2 28,6 1 25 --- --- 1 3,6 --- --- 5 8,2 

11 --- --- 2 15,4 1 5,3 2 5,4 2 3,8 1 4,2 8 5,5 

12 1 100 19 51,4 12 17,9 5 4,3 3 1,7 3 3,6 43 8,9 

13 --- --- 1 100 1 50 --- --- --- --- --- --- 2 8 

14 1 100 7 43,8 3 8,6 1 1,2 3 2,4 2 3,1 17 5,2 

15 --- --- 2 50 3 20 1 5,9 --- --- --- --- 6 7,2 

16 1 100 --- --- --- --- --- --- --- --- --- --- 1 2,5 

17 --- --- --- --- 2 12,5 --- --- --- --- --- --- 2 2,2 

18 --- --- --- --- 3 27,3 --- --- --- --- --- --- 3 4,3 

19 --- --- 4 50 --- --- --- --- --- --- --- --- 4 6 

20 --- --- 2 25 2 11,8 --- --- 1 3,2 --- --- 5 6,3 

21 --- --- 2 66,7 2 40 1 16,7 --- --- --- --- 5 12,2 

22 --- --- 3 42,9 2 22,2 1 6,7 --- --- --- --- 6 9,4 

23 --- --- 9 31 8 20 2 3,2 4 6,1 --- --- 23 10,7 

24 1 100 9 60 11 22,4 5 8,3 1 2,1 --- --- 27 15,6 

25 --- --- --- --- 1 50 --- --- --- --- --- --- 1 4 

26 2 100 5 50 1 6,7 1 7,1 1 5,3 --- --- 10 14,5 

27 --- --- 1 50 4 33,3 --- --- --- --- --- --- 5 10,4 

28 --- --- --- --- 2 40 --- --- --- --- 1 25 3 15,8 

29 --- --- --- --- 1 50 --- --- --- --- --- --- 1 5,9 

30 2 100 5 41,7 2 12,5 1 10 2 11,1 3 18,8 15 20,3 

31 --- --- --- --- --- --- 1 50 --- --- --- --- 1 9,1 

32 --- --- 4 57,1 3 42,9 --- --- --- --- --- --- 7 21,9 

33 1 100 4 23,5 3 10,7 --- --- 3 6 1 5 12 8,6 

34 --- --- 3 50 6 50 --- --- 1 14,3 --- --- 10 23,8 

35 --- --- 3 100 1 14,3 --- --- 1 16,7 --- --- 5 20 

36 --- --- 4 50 1 12,5 3 18,8 2 10,5 --- --- 10 14,5 

37 --- --- --- --- 1 25 1 14,3 1 6,7 --- --- 3 7,7 

38 --- --- --- --- 4 57,1 1 9,1 --- --- --- --- 5 11,9 

39 2 100 1 50 4 26,7 2 12,5 2 20 1 7,1 12 20,3 

40 1 100 --- --- 1 33,3 2 20 --- --- --- --- 4 12,9 

41 --- --- 4 57,1 3 33,3 2 11,8 --- --- 1 6,7 10 16,7 

42 --- --- 1 50 2 22,2 --- --- --- --- --- --- 3 8,8 

43 --- --- 5 83,3 1 33,3 --- --- --- --- --- --- 6 11,5 

44 --- --- 1 25 1 12,5 --- --- --- --- --- --- 2 3,8 

45 --- --- 2 66,7 1 33,3 4 23,5 1 14,3 1 10 9 22,5 

46 1 100 --- --- --- --- --- --- --- --- --- --- 1 9,1 

47 --- --- 1 50 1 20 --- --- --- --- --- --- 2 7,1 

48 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



EuroNeoNet 


Unit 

Code 

Mortality Rate against Gestational Age by Participating Unit 


N % N % N % N % N % N % N % 

49 --- --- 1 100 1 12,5 --- --- 1 14,3 --- --- 3 13,6 

50 --- --- 1 25 2 33,3 --- --- 2 28,6 --- --- 5 18,5 

51 2 50 3 20 --- --- 4 14,3 3 7,7 --- --- 12 9,9 

52 2 100 9 33,3 1 4,2 5 15,6 2 5,3 3 11,1 22 14,7 

53 --- --- 2 66,7 1 12,5 --- --- --- --- 1 20 4 13,3 

54 --- --- 3 100 --- --- --- --- --- --- 1 25 4 30,8 

55 2 100 7 50 13 25,5 5 11,4 1 2,4 1 3,1 29 15,7 

56 --- --- 1 33,3 --- --- --- --- --- --- --- --- 1 5,9 

57 3 100 3 60 1 11,1 1 7,7 --- --- --- --- 8 14,8 

58 1 100 2 40 1 12,5 --- --- 1 5 --- --- 5 8,2 

59 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

60 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

61 --- --- 2 40 --- --- 1 11,1 --- --- --- --- 3 6,7 

62 --- --- 5 100 4 44,4 2 50 --- --- --- --- 11 33,3 

63 --- --- 6 85,7 10 41,7 4 16 1 2,9 --- --- 21 17,4 

64 --- --- 1 100 1 14,3 --- --- --- --- --- --- 2 4,9 

65 --- --- 3 60 2 22,2 1 8,3 --- --- --- --- 6 15,8 

66 1 50 3 27,3 3 27,3 1 4 --- --- --- --- 8 11,6 

67 --- --- 8 44,4 6 26,1 5 12,5 --- --- --- --- 19 15,2 

68 1 100 4 80 3 17,6 --- --- --- --- --- --- 8 14,3 

69 1 100 --- --- 2 50 --- --- --- --- --- --- 3 13,6 

70 --- --- 4 33,3 5 29,4 2 8,7 1 2,3 --- --- 12 10,3 

71 --- --- 3 42,9 1 16,7 1 25 --- --- --- --- 5 15,6 

72 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

73 --- --- 2 100 --- --- --- --- --- --- --- --- 2 8 

74 --- --- 4 30,8 1 4,2 4 11,4 --- --- --- --- 9 7,4 

75 --- --- 8 66,7 --- --- 1 4,5 3 7,9 --- --- 12 12 

76 --- --- 2 10,5 1 4,2 1 3,8 1 1,8 --- --- 5 3,4 

77 --- --- 2 18,2 1 11,1 --- --- 1 5 --- --- 4 5,9 

78 --- --- 2 100 --- --- 1 6,3 --- --- 1 20 4 8,3 

79 --- --- 2 25 3 27,3 --- --- --- --- 1 8,3 6 7,4 

80 --- --- --- --- --- --- 1 14,3 1 11,1 --- --- 2 5,1 

81 --- --- 5 62,5 5 27,8 1 3,3 --- --- 1 5,3 12 10 

82 --- --- 3 42,9 --- --- --- --- 1 3,8 --- --- 4 6,3 

83 8 88,9 2 16,7 2 5,9 4 9,5 --- --- --- --- 16 9,2 

84 --- --- 4 36,4 3 20 --- --- 2 5,7 --- --- 9 10,2 

85 1 100 --- --- 1 20 1 12,5 --- --- --- --- 3 8,8 

86 --- --- 3 42,9 --- --- --- --- --- --- --- --- 3 6 

87 3 100 1 100 2 20 --- --- --- --- --- --- 6 8,8 

88 3 75 12 52,2 2 6,7 5 16,1 3 6,5 --- --- 25 16,1 

89 --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

90 --- --- --- --- 1 9,1 --- --- 1 2,7 --- --- 2 2,8 

91 1 100 2 50 1 20 --- --- --- --- 1 20 5 10,6 

92 5 100 11 33,3 9 20,5 6 12,5 2 5,4 1 4,3 34 17,9 

93 12 57,1 8 30,8 2 6,5 2 4,2 6 6,9 2 6,3 32 13,1 

94 --- --- 3 9,4 1 3,1 --- --- --- --- --- --- 4 2,7 

95 4 100 8 88,9 2 100 3 23,1 5 26,3 1 9,1 23 39,7 

96 --- --- --- --- 1 7,7 --- --- --- --- 1 14,3 2 2,9 

TOTAL 83 71,6 282 38,2 199 15,8 102 5,9 69 2,8 31 2,7 766 10,3 



EuroNeoNet 


6.19.3 Mortality Standardized Rate by Perinatal Risk Factors. 

Graph 6.19.1, corresponds to the 95% CI for the standardised Mortality adjusted rate. 

Graph 6.19.3 

The results for Units 1, 5, 14, 16, 17, 25, 74, 76, 77, 81, 83, 90, 94 and 96 reached statistical significant relevance, being the 

mortality rate for these Units significantly smaller than the one expected according to the standard’s population mortality 

distribution. On the other hand Units 39, 45, 55, 67 and 95 had a bigger significant mortality rate than the one expected 

according to the standard’s population mortality distribution. 

Units 2, 48, 59, 60 and 89 didn’t register mortality. 

Note 1: Standardization items: Birth weight Z-Score by gestational age, Prenatal Steroids use, 1-min 

Apgar Score, 5-min Apgar Score, Multiple Gestation, Mode of Delivery and Major Birth Defects 




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6.19.4 Excess/Defect analysis. 

As the study of mortality is one of the main objectives of the ENS Project, in this 

section we will try to explain in more detail how the different Units behave in 

relation with the standard population. 

Table 6.19.4 shows the observed number of deaths, the expected number of 

deaths according to the sample size in each Unit and the difference between 

these two numbers. All these calculations have been done considering the 

different groups by birth weight. 

The explanation for Table 6.19.4 is the following: 

When SMR is under 1, the table will give us the number of deaths that did not 

appear and should in relation with general population; whereas when the SMR 

is above 1, the table shows the excess number of deaths. 

Table 6.19.4 

Unit Code 

Observed 

nº of deaths 

Expected 

nº of deaths 

by BW 

SMR 

Excess/Defect 

nº of deaths 

76 5 18,3 0,27 -13,3 

14 16 28,6 0,56 -12,6 

83 16 28,1 0,57 -12,1 

94 4 15,4 0,26 -11,4 

93 29 38,8 0,75 -9,8 

81 12 21,6 0,55 -9,6 

1 5 13,0 0,39 -8,0 

5 10 17,7 0,57 -7,7 

17 2 8,7 0,23 -6,7 

74 9 15,4 0,58 -6,4 

96 2 8,3 0,24 -6,3 

33 11 16,7 0,66 -5,7 

89 0 4,5 0,00 -4,5 

77 4 8,0 0,50 -4,0 

19 4 7,7 0,52 -3,7 

90 2 5,5 0,37 -3,5 

48 0 3,4 0,00 -3,4 

11 8 11,1 0,72 -3,1 

75 11 13,8 0,80 -2,8 

25 1 3,7 0,27 -2,7 

82 4 6,6 0,61 -2,6 

16 1 3,5 0,29 -2,5 

79 6 8,3 0,72 -2,3 

18 3 5,3 0,57 -2,3 

86 3 5,3 0,57 -2,3 



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Unit Code 

Observed 

nº of deaths 

Expected 

nº of deaths 

by BW 

SMR 

Excess/Defect 

nº of deaths 

60 0 2,2 0,00 -2,2 

91 5 7,1 0,70 -2,1 

2 0 1,9 0,00 -1,9 

4 5 6,5 0,77 -1,5 

3 13 14,4 0,90 -1,4 

15 6 7,4 0,81 -1,4 

20 5 6,3 0,79 -1,3 

44 2 3,3 0,61 -1,3 

51 12 13,1 0,91 -1,1 

59 0 1,0 0,00 -1,0 

80 2 3,0 0,66 -1,0 

78 3 4,0 0,75 -1,0 

47 2 2,8 0,72 -0,8 

9 2 2,8 0,73 -0,8 

73 2 2,6 0,76 -0,6 

61 3 3,6 0,83 -0,6 

8 1 1,5 0,68 -0,5 

72 0 0,5 0,00 -0,5 

70 12 12,2 0,98 -0,2 

7 0 0,2 0,00 -0,2 

63 6 6,2 0,97 -0,2 

29 1 1,1 0,90 -0,1 

58 4 4,1 0,98 -0,1 

64 2 2,1 0,96 -0,1 

42 3 3,1 0,97 -0,1 

31 1 1,0 1,05 0,0 

22 6 5,9 1,01 0,1 

37 2 1,9 1,05 0,1 

56 1 0,9 1,10 0,1 

53 4 3,8 1,05 0,2 

46 1 0,8 1,24 0,2 

13 2 1,7 1,15 0,3 

6 17 16,7 1,02 0,3 

69 3 2,6 1,16 0,4 

87 6 5,5 1,08 0,5 

21 5 4,4 1,13 0,6 

34 5 4,4 1,15 0,6 

85 3 2,3 1,28 0,7 

49 3 2,3 1,31 0,7 

10 5 4,1 1,21 0,9 

40 3 1,9 1,54 1,1 

26 10 8,7 1,15 1,3 



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Unit Code 

Observed 

nº of deaths 

Expected 

nº of deaths 

by BW 

SMR 

Excess/Defect 

nº of deaths 

23 22 20,3 1,09 1,7 

65 6 4,2 1,43 1,8 

38 5 3,2 1,58 1,8 

71 5 3,1 1,59 1,9 

36 9 7,1 1,27 1,9 

66 8 6,0 1,33 2,0 

28 3 1,0 3,00 2,0 

27 5 3,0 1,67 2,0 

68 8 5,7 1,40 2,3 

43 6 3,7 1,63 2,3 

57 7 4,6 1,52 2,4 

32 5 2,4 2,07 2,6 

12 42 39,4 1,07 2,6 

84 9 6,4 1,41 2,6 

35 5 2,2 2,27 2,8 

54 4 0,9 4,64 3,1 

52 21 17,7 1,19 3,3 

50 5 1,6 3,10 3,4 

24 22 17,4 1,26 4,6 

41 9 4,2 2,12 4,8 

62 9 3,6 2,51 5,4 

88 24 18,2 1,32 5,8 

45 9 2,8 3,21 6,2 

30 14 7,6 1,85 6,4 

39 12 5,0 2,42 7,0 

67 19 10,1 1,87 8,9 

92 30 21,1 1,42 8,9 

95 23 13,4 1,72 9,6 

55 29 12,9 2,25 16,1 



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7 LENGTH OF STAY ANALYSIS FOR VLGAI DISCHARGED TO 

HOME. 

7.1 Sample Size 

In this section the length of stay of VLGAI is going to be analysed. Firstly the 

sample size has to be determined. From the global set of data, infants that died, 

were transferred or are still hospitalised are going to be excluded of the analysis 

in this section. The only infants to be considered in this analysis are those 

dicharged home. The valid sample size is the following: 

Sample Size 

(General Analysis) 

7,437 

Excluded 

(Units 5 

babies admitted) 

N=7,432 

Died 

N=766 

Transferred 

N=1,747 

Home 

N=4,899 

Still Hospitalized 

N=20 

Missing Data 

N=5 

Complete Data 

N=4,894 

In all this section, sample size will exclude: 

1. Deaths in Delivery Room. 

2. Units with 5 or less babies admitted to the NICU 

3. Babies not discharged home (died, transferred or still hospitalized as of first birthday) 


Note: Excluded babies died in Delivery Room, units with 5 or less babies admitted in the NICU and babies not discharged home

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7.2 Lenght of stay (days) description 

The valid sample size finally has been of 4,894 infants because. 

Table 7.2.1 shows the parametric and non-parametric statistics for the Length of 

Stay. The global mean stay for the 94 Units analysed has been of 55.6 days 

with a standard desviation of 30.8 days. 

Note: Missing Age at admission has been considered as 0 days. 

Table 7.2.1 

Length of Stay by Unit Participating in the ENS Project 

Unit Code N 95% CI () Q 2 [Q 1 ,Q 3 ] 

1 60 45.8 ± 21.2 [40.3;51.3] 40 [33;66,75] 

2 17 45.4 ± 19.2 [35.5;55.2] 42 [28;53,5] 

3 127 40.3 ± 25.3 [35.8;44.7] 33 [24;49] 

4 43 58.7 ± 34.3 [48.2;69.3] 49 [37;74] 

5 109 49.5 ± 25.4 [44.7;54.3] 42 [33;56] 

6 128 44.6 ± 26.6 [40;49.3] 37 [27;53,25] 

8 19 41.4 ± 36.2 [24;58.9] 37 [26;46] 

9 20 46.9 ± 21.7 [36.7;57.1] 44,5 [32,75;66] 

10 34 47.1 ± 20.5 [39.9;54.2] 43 [33,5;53,25] 

11 39 42.3 ± 26.7 [35.2;49.3] 36 [26;48] 

12 311 51.2 ± 34.1 [47.4;55] 43 [30;62] 

13 15 46.4 ± 22.7 [33.8;59] 38 [29;71] 

14 229 49.5 ± 28.1 [45.9;53.2] 42 [31,5;59] 

15 52 72.6 ± 51.7 [58.2;87] 60 [48,25;76] 

16 31 59.8 ± 26.5 [50.1;69.6] 51 [42;76] 

17 45 66 ± 24.5 [58.7;73.4] 62 [47;82,5] 

18 37 63 ± 25.1 [54.6;71.4] 61 [45,5;77] 

19 41 59.7 ± 31.4 [49.8;69.6] 52 [38;68] 

20 56 63.7 ± 24.6 [57.1;70.3] 57,5 [43,25;77] 

21 32 50.6 ± 18.7 [43.9;57.4] 45 [38,5;53,75] 

22 16 57.7 ± 20.2 [46.9;68.4] 51 [42,75;66] 

23 84 70.2 ± 32 [63.2;77.1] 66 [44,25;87,5] 

24 67 77.2 ± 25.2 [71.1;83.4] 75 [57;96] 

25 24 46.4 ± 21.7 [37.3;55.6] 47 [29,75;58] 

26 37 62.8 ± 27.7 [53.6;72] 61 [36;83,5] 

27 34 58.5 ± 26.7 [49.1;67.8] 55 [42,75;67,75] 

28 16 54.6 ± 20.7 [43.5;65.6] 56,5 [37;70,75] 

29 15 48.2 ± 11.1 [42.1;54.3] 45 [39;57] 

30 54 65.7 ± 37.5 [55.4;75.9] 56 [36,75;84,25] 

31 9 35.1 ± 20.4 [19.5;50.8] 25 [18,5;48,5] 

32 25 67.3 ± 32.4 [54;80.7] 64 [41;88] 

33 110 53.9 ± 25.7 [49;58.7] 46 [32,75;76,5] 

34 28 68.8 ± 29.9 [57.2;80.4] 67 [54;82,25] 

35 19 68.7 ± 30.3 [54.1;83.3] 63 [47;91] 

36 58 48.9 ± 29.3 [41.2;56.6] 36,5 [27,75;60,5] 

37 29 39.1 ± 21.2 [31;47.1] 37 [19;56] 

38 33 64.4 ± 70.6 [39.3;89.4] 51 [33,5;69] 

39 44 54.9 ± 23.1 [47.9;62] 49,5 [37,25;68,5] 

40 26 57.5 ± 23.2 [48.1;66.8] 51,5 [38,75;67,5] 

41 49 53.5 ± 27.8 [45.2;61.5] 49 [33;67] 

42 27 65.1 ± 37.3 [50.4;79.9] 58 [37;80] 



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Table 7.2.1 

Length of Stay by Unit Participating in the ENS Project 

Unit Code N 95% CI () Q 2 [Q 1 ,Q 3 ] 

43 45 43.2 ± 19.4 [37.3;49] 41 [28,5;50] 

44 48 56.8 ± 27.4 [48.9;64.8] 49,5 [39;72,25] 

45 28 50.3 ± 33.1 [37.4;63.1] 42 [29;59,75] 

46 10 62.3 ± 30.9 [40.2;84.4] 51 [46,75;80] 

47 25 49.8 ± 26.7 [38.7;60.8] 43 [31;62] 

48 28 52.1 ± 19.7 [44.4;59.7] 46 [40,25;57] 

49 19 64.3 ± 17.2 [56;72.6] 66 [52;79] 

50 22 86.4 ± 85.5 [48.4;124.3] 73 [42,5;90,5] 

51 100 64.4 ± 38.7 [56.7;72.1] 50 [37;78] 

52 123 66 ± 41.3 [58.6;73.4] 52 [38;89] 

53 24 55.2 ± 24.2 [45;65.4] 51 [33,25;77] 

54 9 51.6 ± 34 [25.4;77.7] 46 [38;55] 

55 129 51.1 ± 27.2 [46.4;55.9] 43 [33;62] 

56 16 60.4 ± 22.4 [48.4;72.3] 58,5 [48;67] 

57 46 61.5 ± 26.1 [53.8;69.3] 58 [39;76,75] 

58 54 51.7 ± 22.7 [45.5;57.9] 48 [32;68] 

59 14 51.4 ± 25 [36.9;65.8] 41,5 [34,75;65,75] 

60 40 60.7 ± 25.9 [52.4;69] 53,5 [40,5;80,5] 

61 37 60.2 ± 22.5 [52.7;67.8] 53 [44;74] 

62 22 52.2 ± 27.6 [40;64.5] 43,5 [31,5;67,75] 

63 99 46.3 ± 25.4 [41.3;51.4] 38 [31;55] 

64 37 40.1 ± 15 [35.1;45.1] 37 [27,5;50] 

65 30 53.6 ± 25.7 [44;3.2] 45,5 [39,25;65,5] 

66 61 71.8 ± 25.7 [65.2;78.4] 69 [56,5;86] 

67 90 63.8 ± 33.7 [56.7;70.9] 55 [39,75;83,5] 

68 45 70.8 ± 28.1 [62.4;79.3] 67 [48;87] 

69 19 43.1 ± 24.3 [31.4;54.8] 36 [28;49] 

70 98 49.6 ± 31.6 [43.3;56] 44 [27;59,5] 

71 26 55 ± 32.9 [41.7;68.3] 43,5 [30,75;72,5] 

73 21 58.7 ± 18.9 [50.1;67.2] 51 [47;73] 

74 37 73.5 ± 39 [60.5;86.5] 62 [45;93] 

75 71 57.2 ± 26.5 [50.9;63.5] 52 [37;71] 

76 35 65.9 ± 42.3 [51.4;80.4] 58 [39;84] 

77 37 66.4 ± 27.7 [57.2;75.7] 62 [44,5;92,5] 

78 37 51.8 ± 25.2 [43.4;60.2] 45 [34;57,5] 

79 47 59.9 ± 25 [52.5;67.2] 55 [45;78] 

80 27 53.4 ± 19.8 [45.6;61.3] 51 [41;65] 

81 65 43.7 ± 22.9 [38.1;49.4] 37 [26;60,5] 

82 45 70 ± 29.7 [61.1;79] 68 [47,5;91] 

83 129 58.2 ± 25.9 [53.6;62.7] 54 [36;77] 

84 76 58.5 ± 28.4 [52;65] 53 [38,25;74,25] 

85 29 63.9 ± 31.1 [52.1;75.7] 57 [39,5;81] 

86 46 69.1 ± 25.6 [61.5;76.7] 58 [48;86] 

87 46 49.8 ± 20.5 [43.8;55.9] 44 [32;66] 

88 60 50.5 ± 28.6 [43.1;57.8] 45,5 [27,25;69,75] 

89 39 40.8 ± 15.9 [35.6;45.9] 37 [31;50] 

90 43 40.8 ± 24.9 [33.1;48.4] 33 [25;43] 

91 30 50.3 ± 20.2 [42.8;57.8] 48,5 [30,5;65,25] 

92 73 59.9 ± 31.1 [52.6;67.2] 54 [35;74,5] 

93 166 51 ± 24.9 [47.2;54.9] 44,5 [32;64,25] 

94 62 64.3 ± 39.1 [54.4;74.2] 55 [38,75;86,25] 

95 30 50 ± 36.5 [36.4;63.7] 35,5 [27,75;70] 

96 50 59 ± 20.7 [51.1;64.9] 57,5 [42;73,5] 

Total 4894 55.6 ± 30.8 [54.7;56.4] 48 [34;70] 



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Graph 7.2.2 corresponds to the 95% CI for the global stay measured in days. The discontinuos line shows the stay mean for the 

global set of Units. 

Graph 7.2.2 

Kruskal- Wallis test for independent samples has been performed. Showing that the length of stay is statistically different between 

Units (p

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8 ANNEX 

Number of babies reported by Unit 70 that fulfilled ENN data inclusion criteria 

are 120. 

A 3.3% (4 babies) died in delivery room. This will be analysed in section 8.1 and 

then admitted babies (116) will be described in detail in section 8.2 and 8.3. 

Reminder of ENN Data Inclusion Criteria: 

Any infant born alive at your hospital, whether or not was admitted to your NICU, should be reported if his/her: 

Birth Weight (BW) is less than 1501 g 

OR 

Gestational Age (GA) is less than 32 wks (31 + 6 days inclusive). 

All livebirths must be reported, no matter if his/her gestational age is below 22 weeks or the birth weight is below 401g. 

All outborn infants of same BW and GA as above, admitted to any location in your hospital within 28 days of birth should 

also be included, only if the baby has never been discharged home. 

Outborn babies admitted to the Neonatal Unit after the 28th day of life, should not be included in the Database, since by 

international definitions those babies are no longer “newborn” but “infants”. 

EuroNeoNet 2010 147

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8.1 Delivery Romm Deaths Description 

Number of babies died in delivery room is too small to perform tables and 

graphs. 

EuroNeoNet 2010 148

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8.2 Demographic Individual Data 

8.2.1 Birth Weight 

Mean birth weight for Unit 70 in 2010 cohort babies has been of 1,276.9 g. 

Extreme values are those under 725.5 g., and above 1,910.5 g. (Percentile 5 


Birth weight (gr.) 

Mean (SD) 1,276.9 (349.8) 

95% CI (Mean) (1,212.6;1,341.3) 

Med [Q 1 ,Q 3 ] 1,300 [990;1,490] 

Min-Max 610 - 2,170 

P 5 -P 95 725.5 - 1,910.5 



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8.2.2 Gestational Age 

Median gestational age for Unit 70 in 2010 cohort babies has been of 30 weeks. 

Extreme values are those under 25 weeks, and above 34 weeks (Percentile 5 


Gestational 

Age (wks.) 

Mean (SD) 29.5 (2.8) 

95% CI (Mean) (29;30.1) 

Med [Q 1 ,Q 3 ] 30 [27.3;31] 

Min-Max 24 - 36 

P 5 -P 95 25 - 34 



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8.2.3 Apgar Scores 

Admitted babies in Unit 70 for 2010 cohort had an 1-min Apgar Score mean of 

of 5.6, and 5-min score mean of 7.9. 

1-min Apgar Score 

5-min Apgar Score 

Mean (SD) 5.6 (2.3) 7.9 (1.8) 

95% CI (Mean) (5.2;6) (7.6;8.2) 

Med [Q 1 ,Q 3 ] 6 [4;8] 8 [7;9] 

Min-Max 0 - 9 0 - 10 

P 5 -P 95 1 - 9 4 - 10 



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8.2.1 Perinatal Risk Factors 

More than half of the population of admitted babies in unit 70 were male 

(59.5%). A 51.7% of babies were multiple and a 65.5% of admitted babies were 

born by caesarean section. An 81% received at least one cycle of Prenatal 

Steroids and a 93.1% Prenatal Care. A 2.6% of admitted babies presented a 

major birth defect. 

N % 

Male 69 59.5 

Multiple Gestation 60 51.7 

Caesarean Section 76 65.5 

Prenatal Steroids (Inc. + Compl.) 94 81 

Prenatal Care 108 93.1 

Major Birth Defects 3 2.6 



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8.2.2 Standardized Percentiles 

Manoeuvres and Diagnoses: 

Resuscitation in Delivery Room, Surfactant Need, RDS and Early Onset Sepsis 

More than ¾ of the population (77.6%) needed some kind of resuscitation in 

delivery room in addition to Oxygen. A 23.3% of babies needed surfactant at 

any time of its stay, being the rate of surfactant within the fist hour of life a 

12.9%. 

A 38.8% of babies were diagnosed of Respiratory Distress Syndrome and a 

0.9% of admitted babies had an early bacterial sepsis episode. 

N % 

Resuscitation in Delivery Room 90 77.6 

Surfactant at any time 27 23.3 

Surfactant within the 1st hour of life 15 12.9 

Respiratory Distress Syndrome 45 38.8 

Early Onset Sepsis 1 0.9 

Next graph plots, the percentile that the previous results represent in the whole 

year cohort. Results for Surfactant at any time are below the 10 th Percentile. 



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Diagnoses: 

Pneumothorax, Necrotizing Enterocholitis, Focal Gastroinestinal Perforation and Steroids for 

CLD. 

Pneumothorax rate is of 5.2%, Necrotizing Enterocholitis of a 4.3% and a 4.3% 

for Focal Gastrointestinal Perforation.Steroids for CLD rate was of a 2.6%. 

N % 

Pneumothorax 6 5.2 

Necrotizing Enterocholitis 5 4.3 

Focal Gastrointetsinal Perfoartion 5 4.3 

Steroids for CLD 3 2.6 


year cohort. Any of the results were beyond the standard limits (below 10 th 

percentile or above 90 th percentile). 



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Morbi-Mortality: 

Severe PIVH, Rop (Grades >=3), BPD, Late Onset Sepsis, Cystic Leukomalacia and Mortality 

Severe PIVH was diagnosed in a 4.5% of babies admitted in Unit Code 70. A 

1.4% of admitted babies were diagnosed of Rop (Gardes >=3) and Cystic PVL 

was found in a 2.8% of babies. Oxygen on week 36 rate was of a 19.7%. 

A 15.5% of babies had at least one late onset sepsis episode and a 10.3% of 

admitted babies died at discharge. 

N % 

Severe PIVH 5 4.5 

Rop (Grades >= 3) 1 1.4 

BPD 13 19.7 

Late Onset Sepsis 18 15.5 

Cystic Leukomalacia 3 2.8 

Mortality 12 10.3 


year cohort. Any of the results were beyond the standard limits (below 10 th 

percentile or above 90 th percentile). 

. 



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8.3 Main Results 

8.3.1 Percentile Position for Main Results. 

Graphic 8.3.1 shows the percentile position for main results for Unit Code 70 

realted to all Units included in the study. Main results are considerd to be 

Mortality, Pneumothorax diagnose, Oxygen on week 36, Prenatal Steroids 

(Incomplete + Complete), PIVH (Grades III or IV) and Late Bacterial Sepsis. 

The percentage shown represents the position that the Unit has inside the total 

set of Units studied. Unit Code 70 is in percentile 52 for Mortality, in percentile 

66 for Pneumothorax, in percentile 64 for Oxygen on week 36, in percentile 74 

for Prenatal Steroids (Incomplete + Complete), in percentile 26 for PIVH 

(Grades III or IV) and finally in percentile 32 for Late Bacterial Sepsis. For all 

main items a positive result is considered a low percentile. 

*This graphic represents the position that the Unit has inside the whole set, NOT its 

intensity. Intensity is described in 8.3.2 graphic. 



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8.3.2 Typified Scores for Main Results 

Graphic 8.3.2 corresponds to the typified score for the standardised rate 

adjusted by Birth Weight for items considered as main results. 

A score above 0 means a positive result and its intensity is given by the score 

itself. As larger the score is, the better is the result (when positive) and when 

negative; as larger it is, the worse is the result. If the stick crosses the 

discontinuous linem the result will be statistically significant. 

Results for PIVH (Grades III or IV) and Late Sepsis can be considered as 

positive. Any of the results reached statistical significance. 

Graph 8.3.2 



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General Contact Information 

For The ENN Project 

Hospital de Cruces 

Unidad Neonatal 5-D 

Plaza de Cruces s/n 

48903 Barakaldo 

Bizkaia (Spain) 

Phone: +34 94 600 63 94 

Fax: +34 94 600 60 76 

e-mail: info.euroneonet@euskalnet.net

Standard Annual Report - Neonatal European Information System

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