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Koh KK, et al. Circulation. 2004

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PDGF<br />

complement<br />

thromboxane A 2<br />

m<strong>et</strong><strong>al</strong>loproteinases<br />

tissue factor<br />

PAI-1<br />

oxygen free radic<strong>al</strong>s<br />

Adhesion<br />

Molecule<br />

Expression<br />

IL-1<br />

TNF<br />

Lymphocyte<br />

Activation<br />

IL-6<br />

IL-11<br />

Cytokines Initiate<br />

Hepatic Synthesis of<br />

Some Proteins<br />

(Acute Phase Reactants<br />

C-reactive protein<br />

amyloid A<br />

haptoglobin<br />

ceruloplasmin<br />

C3, C4<br />

fibrinogen<br />

vWF<br />

PAI-1<br />

Lp(a)<br />

+<br />

-<br />

<strong>al</strong>bumin<br />

transferrin<br />

A-I, A-II<br />

+<br />

C3<br />

amyloid A<br />

a 1 -acid glycoprotein<br />

<strong>Koh</strong> <strong>KK</strong>. Cardiovasc Res.<br />

2002;55:714. (Review)

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