Koh KK, et al. Circulation. 2004
Koh KK, et al. Circulation. 2004
Koh KK, et al. Circulation. 2004
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Fenofibrate<br />
• Peroxisome Proliferator-Activated Receptors<br />
Transcription factors belonging to nuclear<br />
receptor superfamily<br />
PPARa, PPARb/d, PPARγ<br />
• Fibrates<br />
Synth<strong>et</strong>ic ligands for PPARa<br />
• PPARa<br />
1. Anti-inflammatory function<br />
2. Reduce oxidative stress<br />
3. Expression of inhibitory protein IkBa<br />
Inhibit NF-kB activation