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Cancer Pharmacogenomics Development, Science, Translation

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Gemcitabine “Pathway”<br />

Gemcitabine<br />

SLC28A1,A2 and A3<br />

SLC29A1 and A2<br />

Deamination<br />

P<br />

CDA<br />

NDPs<br />

Gemcitabine<br />

RRM1<br />

RRM2<br />

Gemcitabine<br />

UMP-CMPK<br />

P P<br />

Gemcitabine<br />

RRM2B<br />

dNDPs<br />

dNTPs<br />

P<br />

P P P<br />

Gemcitabine<br />

P P<br />

dNTPs<br />

P<br />

Nucleus

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