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Calcium Microcrystalline Hydroxyapatite - Douglas Laboratories

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<strong>Douglas</strong><br />

<strong>Laboratories</strong> ®<br />

Product Data<br />

<strong>Calcium</strong> <strong>Microcrystalline</strong><br />

<strong>Hydroxyapatite</strong><br />

DESCRIPTION<br />

<strong>Calcium</strong> <strong>Microcrystalline</strong> <strong>Hydroxyapatite</strong>, provided<br />

by <strong>Douglas</strong> <strong>Laboratories</strong> ® , supplies 250 mg of<br />

elemental calcium from 1,000 mg of microcrystalline<br />

hydroxyapatite(MCHC), a bioavailable source of<br />

calcium derived from whole bone.<br />

FUNCTIONS<br />

The adult human body contains approximately 1,200 g<br />

of calcium, about 99% of which is present in the<br />

skeleton. Bone is constantly turning over, a continuous<br />

process of formation and resorption. In children and<br />

adolescents, the rate of formation of bone mineral<br />

predominates over the rate of resorption. In later life,<br />

resorption predominates over formation. Therefore, in<br />

normal aging, there is a gradual loss of bone.<br />

Osteoporosis, a condition of reduced bone mineral<br />

density that can increase risk of fractures, affects a large<br />

proportion of the elderly in developed countries.<br />

Caucasian and Asian women typically have low peak<br />

bone densities, and therefore, are at the greatest risk of<br />

developing osteoporosis. It is generally accepted that<br />

obtaining enough dietary calcium throughout life can<br />

significantly decrease the risk of developing<br />

osteoporosis. Among other factors, such as regular<br />

exercise, gender and race, calcium supplementation<br />

during childhood and adolescence appears to be a<br />

prerequisite for maintaining adequate bone density later<br />

in life. But even elderly osteoporotic patients can benefit<br />

significantly from supplementation with dietary<br />

calcium.<br />

<strong>Calcium</strong> <strong>Microcrystalline</strong> <strong>Hydroxyapatite</strong> provides a<br />

highly beneficial source of dietary calcium together with<br />

other nutrients that assist in the maintenance of healthy<br />

bone structure and function. For example, boron affects<br />

the composition, structure, and strength of bone. It<br />

appears to be necessary for calcium and magnesium<br />

absorption, their adequate renal reabsorption, and their<br />

incorporation into the bone matrix. Boron is absorbed at<br />

about 90% efficiency and is rapidly distributed among<br />

the tissues.<br />

INDICATIONS<br />

<strong>Calcium</strong> <strong>Microcrystalline</strong> <strong>Hydroxyapatite</strong> tablets may<br />

be a useful dietary supplement for individuals who wish<br />

to increase their intake of calcium and other nutritional<br />

factors for the maintaining of healthy bone function.<br />

FORMULA (#83018)<br />

Each Tablet Contains:<br />

<strong>Calcium</strong> <strong>Microcrystalline</strong> <strong>Hydroxyapatite</strong>1,000 mg<br />

Yielding:<br />

<strong>Calcium</strong> ........................................................250 mg<br />

Phosphorus ...................................................130 mg<br />

Protein ..........................................................250 mg<br />

(as Collagen Glycosaminoglycans and Substituent<br />

Amino Acids)<br />

Boron(as Boron Aspartate) ...........................2.5 mg<br />

SUGGESTED USE<br />

Adults take 2-4 tablets daily with meals or as directed<br />

by a physician.<br />

SIDE EFFECTS<br />

No adverse side effects reported.<br />

STORAGE<br />

Store in a cool, dry place, away from direct light.<br />

Keep out of reach of children.<br />

REFERENCES<br />

Barger-Lux MJ, Heaney RP. The role of calcium intake in preventing bone<br />

fragility, hypertension, and certain cancers. J Nutr 1994;124:1406S-1411S.<br />

Benderdour M, Bui-Van T, Dicko A, Belleville F. In vivo and in vitro effects of<br />

boron and boronated compounds. J Trace Elem Med Biol 1998;12:2-7.<br />

O’Brien KO. Combined calcium and vitamin D supplementation reduces bone<br />

loss and fracture incidence in older men and women. Nutr Rev 1998;56:148-50.<br />

Pines A, Raafat H, Lynn AH, Whittington J. Clinical trial of microcrystalline<br />

hydroxyapatite compound (‘Ossopan’) in the prevention of osteoporosis due to<br />

cortcosteroid therapy. Curr Med Res Opin 1984;8:734-42.Uusi-Rasi K, Sievanen<br />

H, Pasanen M, Oja P, Vuori I. Maintenance of body weight, physical activity and<br />

calcium intake helps preserve one mass in elderly women. Osteoporos Int<br />

2001;12(5):373-9.<br />

(continued on reverse)


These statements have not been evaluated by the Food and Drug Administration.<br />

This product is not intended to diagnose, treat, cure, or prevent any disease.<br />

Distributed by<br />

<strong>Douglas</strong> <strong>Laboratories</strong><br />

552 Newbold St., London, Ontario N6E 2S5<br />

Phone: 866.856.9954 Fax: 888.220.9441<br />

Email: info@douglaslabs.ca Website: www.douglaslabs.ca<br />

2003 <strong>Douglas</strong> <strong>Laboratories</strong>, INC. All Rights Reserved

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