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Management of Extravasation of Cytotoxic Drugs in Children

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Appendix 2: Non- <strong>Cytotoxic</strong> <strong>Extravasation</strong><br />

Determ<strong>in</strong>e which type <strong>of</strong> drug has extravasated, then us<strong>in</strong>g the table; follow the<br />

treatment procedure for that class <strong>of</strong> extravasated drug.<br />

IRRITANTS<br />

Adrenal<strong>in</strong>e<br />

(H)<br />

Amiodarone<br />

(C)<br />

Clarithromyc<strong>in</strong><br />

(C)<br />

Diazemuls<br />

(C)<br />

Dobutam<strong>in</strong>e<br />

(H)<br />

Dopam<strong>in</strong>e<br />

(H)<br />

Erythromyc<strong>in</strong><br />

(C)<br />

Foscarnet<br />

(C)<br />

Noradrenal<strong>in</strong>e<br />

(H)<br />

Phenobarbitone<br />

(C)<br />

Promethaz<strong>in</strong>e<br />

(C)<br />

Vancomyc<strong>in</strong><br />

(C)<br />

VESICANTS<br />

Aciclovir<br />

(C)<br />

Am<strong>in</strong>ophyll<strong>in</strong>e<br />

(H)<br />

Amphoteric<strong>in</strong><br />

(C)<br />

Calcium Chloride<br />

(H)<br />

Calcium Gluconate<br />

(H)<br />

Cefotaxime<br />

(C)<br />

Diazepam<br />

(C)<br />

Digox<strong>in</strong><br />

(C)<br />

Fluoresce<strong>in</strong><br />

(C)<br />

Ganciclovir<br />

(C)<br />

Hypertonic NaCl sol n > 5% (H)<br />

Phentolam<strong>in</strong>e<br />

(C)<br />

Parentral Nutrition<br />

(H)<br />

Phenyto<strong>in</strong><br />

(H)<br />

Potassium Chloride<br />

(>40mmols/l) (H)<br />

Sodium Bicarbonate<br />

(H)<br />

Ven<strong>of</strong>er<br />

(C)<br />

<strong>Management</strong> <strong>of</strong> <strong>Extravasation</strong> <strong>of</strong> <strong>Cytotoxic</strong> <strong>Drugs</strong> <strong>in</strong> <strong>Children</strong><br />

Ratified: Review: 16

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