RIDL; What Is It? How Does It Work? Does It Work? And What's In ...

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OX513A Life Table comparison to WT Parameter Strain Average Mean Rank p-Value Eggs laid per female RIDL 74.86 ± 16.94 16.03 0.740 wild type 63.07 ± 6.855 14.97 Larvae hatched per egg batch. Sterile eggs per egg batch RIDL 49.86 ± 8.306 17.70 0.171 wild type 31.60 ± 5.237 13.30 RIDL 25.00 ± 3.349 14.33 0.468 wild type 31.47 ± 5.57 16.67 Days spent in L4 RIDL 2.59 ± 0.06 142.84 0.851 wild type 2.57 ± 0.58 141.20 Days spent at pupal stage Days from hatching to adult RIDL 2.29 ± 0.042 133.52 0.141 wild type 2.36 ± 0.40 144.99 RIDL 7.85 ± 0.071 130.19 0.200 wild type 7.49 ± 0.055 141.28 Study performed by IMR
OX513A Gene stability Stable for over 60 generations as a homozygous line • Molecular and marker expression analysis Re-exposure to transposase does not cause movement at detectable levels Penetrance of phenotype unchanged
Page 1 and 2: RIDL; What Is It How Does It Work D
Page 3 and 4: What is RIDL
Page 5 and 6: Pest control using GM insects Popu
Page 7 and 8: Success of SIT SIT has been succes
Page 9 and 10: A Genetic Solution for mosquito con
Page 11 and 12: OX513 - structure drosomycin 3' UTR
Page 14 and 15: Microinjection Produce RIDL line M
Page 16 and 17: RIDL gene function Bi-sex RIDL is
Page 18 and 19: RIDL; summary of mode of action Ac
Page 20 and 21: Traditional approaches Fogging - ar
Page 22 and 23: Integrated Vector Control Strategy
Page 24 and 25: Filter colony UK - overview Stabili
Page 26 and 27: 2010 suppression trial; methods Mas
Page 28 and 29: Trial process: Monitoring Monitori
Page 30 and 31: Does it work
Page 32 and 33: OX513A molecular characterisation
Page 34 and 35: Contained mating trials results Pe
Page 38 and 39: OX513A strain background Insectici
Page 40 and 41: 2010 Cayman Suppression Trial Aims
Page 42 and 43: Results - Fluorescent score % Fluor
Page 44 and 45: Cayman field trial summary Trial w
Page 46 and 47: Itaberaba - Field site N C T1 T2 20
Page 48 and 49: RIDL ® bringing new technology to
Page 50 and 51: Community Engagement Community eng
Page 52 and 53: What’s in the future
Page 54 and 55: On-going control programmes Curren
Page 56 and 57: New species (mosquitoes) Culex sp.
Page 58 and 59: Bi-sex RIDL technology Design of t
Page 60 and 61: OX3604C Cage suppression trial resu
Page 62 and 63: Acknowledgments USDA/CMAVE (Gary C

RIDL; What Is It? How Does It Work? Does It Work? And What's In ...

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