RIDL; What Is It? How Does It Work? Does It Work? And What's In ...

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Background: SIT and mosquitoes >20 trials in 1970’s – 1980’s [Reviewed by Mark Benedict and Alan Robinson (2003) Trends Parasitol. 19:349] • Variable success • Some problems revealed: Immigration of pre-mated females Poor competitiveness of irradiated/chemosterilised males Breakdown and semi-sterility of strains using translocations or other chromosomal rearangments.
A Genetic Solution for mosquito control Based on Sterile <strong>In</strong>sect Technique Uses modern molecular biology techniques to insert a lethal gene into insects Sterile transgenic insects can be used to control a range of pests. “birth control for mosquitoes”
Page 1 and 2: RIDL; What Is It How Does It Work D
Page 3 and 4: What is RIDL
Page 5 and 6: Pest control using GM insects Popu
Page 7: Success of SIT SIT has been succes
Page 11 and 12: OX513 - structure drosomycin 3' UTR
Page 14 and 15: Microinjection Produce RIDL line M
Page 16 and 17: RIDL gene function Bi-sex RIDL is
Page 18 and 19: RIDL; summary of mode of action Ac
Page 20 and 21: Traditional approaches Fogging - ar
Page 22 and 23: Integrated Vector Control Strategy
Page 24 and 25: Filter colony UK - overview Stabili
Page 26 and 27: 2010 suppression trial; methods Mas
Page 28 and 29: Trial process: Monitoring Monitori
Page 30 and 31: Does it work
Page 32 and 33: OX513A molecular characterisation
Page 34 and 35: Contained mating trials results Pe
Page 36 and 37: OX513A Life Table comparison to WT
Page 38 and 39: OX513A strain background Insectici
Page 40 and 41: 2010 Cayman Suppression Trial Aims
Page 42 and 43: Results - Fluorescent score % Fluor
Page 44 and 45: Cayman field trial summary Trial w
Page 46 and 47: Itaberaba - Field site N C T1 T2 20
Page 48 and 49: RIDL ® bringing new technology to
Page 50 and 51: Community Engagement Community eng
Page 52 and 53: What’s in the future
Page 54 and 55: On-going control programmes Curren
Page 56 and 57: New species (mosquitoes) Culex sp.
Page 58 and 59:
Bi-sex RIDL technology Design of t
Page 60 and 61:
OX3604C Cage suppression trial resu
Page 62 and 63:
Acknowledgments USDA/CMAVE (Gary C
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RIDL; What Is It? How Does It Work? Does It Work? And What's In ...

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