University of Paris, CNRS Department of Epigenetics and Cell Fate

Recent publications from the lab:
A new family of human proteins that bind methylated DNA and repress transcription.
Filion et al, Molecular and Cellular Biology, (2006)
Assessment of sera for Chromatin-Immunoprecipitation.
Nguyen J., et al BioTechniques (2008)
ZBTB4 represses transcription of p21CIP1 and controls the cellular response to p53.
Weber et al EMBO J, (2008)
The cell biology of DNA methylation
Prokhortchouk E. and Defossez P.A.
Biochim Biophys Acta. (2008)
Many paths to one goal The proteins that bind methylated DNA in eukaryotes
Sasai et al Int. J. Dev. Biol., (2009)
The human protein kinase HIPK2 phosphorylates and downregulates the methylbinding
transcription factor ZBTB4.
Yamada et al Oncogene, (2009)
Sequence-specific recognition of methylated by human Zinc finger proteins.
Sasai et al Nucleic Acids Research, (2010).
The human proteins MBD5 and MBD6 associate with heterochromatin but do not
bind methylated DNA.
Laget et al, PLoS ONE (2010).
Mammalian Methyl-Binding Proteins: what might they do
Joulie et al BioEssays, in press.