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Acute ischemic stroke treatment in a nutshell

Acute ischemic stroke treatment in a nutshell

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WARFARIN<br />

Secondary prevention: Prior TIA or m<strong>in</strong>or <strong>stroke</strong> (EAFT)<br />

• Warfar<strong>in</strong> (INR 2.5 to 4.0) vs placebo<br />

Effective NNT over 2 y = 6-7<br />

• Aspir<strong>in</strong> 300 mg om vs placebo<br />

Safe alternative NNT over 2 y = 50<br />

• Warfar<strong>in</strong> vs Aspir<strong>in</strong><br />

Warfar<strong>in</strong> superior NNT over 2 y =7-8<br />

At 28<br />

months<br />

Warfar<strong>in</strong><br />

Placebo<br />

P value<br />

Aspir<strong>in</strong><br />

Placebo<br />

P value<br />

Stroke<br />

8.9%<br />

23.4%<br />

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