- Page 1: Evidence Report/Technology Assessme
- Page 6 and 7: • Appropriate use of antibiotic p
- Page 8 and 9: Chapter 17. Prevention of Ventilato
- Page 10 and 11: PART V. ANALYZING THE PRACTICES ...
- Page 12 and 13: This evidence-based review also foc
- Page 14 and 15: iases of these studies. Authors wer
- Page 16 and 17: Clear Opportunities for Safety Impr
- Page 18 and 19: Conclusions This report represents
- Page 21: PART I. OVERVIEW Chapter 1. An Intr
- Page 24 and 25: patient will receive the wrong medi
- Page 26 and 27: coordinated efforts of multiple mem
- Page 28 and 29: inevitably missed some of both. Mor
- Page 30 and 31: Clinicians and trainees will, we ho
- Page 32 and 33: 5. Meltzer DO, Manning WG, Shah M,
- Page 35 and 36: Chapter 2. Drawing on Safety Practi
- Page 37 and 38: sciences” of organizational theor
- Page 39 and 40: Chapter 3. Evidence-based Review Me
- Page 41 and 42: The Editors also performed independ
- Page 43 and 44: Evaluation of Safety Practices For
- Page 45 and 46: Review Process Authors submitted wo
- Page 47: 20. Juni P, Witschi A, Bloch R, Egg
- Page 51 and 52: Chapter 4. Incident Reporting Heidi
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In 1995, hospital-based surveillanc
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prove to be particularly useful in
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Table 4.1. Examples of events repor
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21. Hart G, Baldwin I, Gutteridge G
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Chapter 5. Root Cause Analysis Heid
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complaints, media stories and other
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investigation in the name of qualit
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PART III. PATIENT SAFETY PRACTICES
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Chapter 6. Computerized Physician O
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Study Outcomes Adverse drug events
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Potential for Harm Faulty decision
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Table 6.1. Studies of computerized
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References 1. Barker KN, Mikeal RL,
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28. Evans RS, Pestotnik SL, Classen
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Hospital pharmacies provide support
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Comment At present, one study provi
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References 1. Dyer CC, Oles KS, Dav
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Chapter 8. Computer Adverse Drug Ev
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Evidence for Effectiveness of the P
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Table 8.1. Included studies of comp
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19. Kuperman GJ, Teich JM, Tanasije
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• Outpatient anticoagulation clin
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of aggressive anticoagulation, it i
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Table 9.1. Studies focused primaril
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Table 9.2. Inpatient anticoagulatio
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Table 9.3. Outpatient self-manageme
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17. Elliott CG, Hiltunen SJ, Suchyt
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100
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eplaced by a fresh and updated medi
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Lastly, we were unable to obtain on
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Table 10.1. Studies evaluating the
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References 1. Bates DW, Cullen DJ,
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110
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drug is ejected into a strip-packin
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Costs and Implementation The cost o
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References 1. Perini VJ, Vermeulen
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Section B. Infection Control Chapte
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Prevalence and Severity of the Targ
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Comment While many studies have inv
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Table 12.1. Fourteen studies of pra
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20. McGuckin M, Waterman R, Porten
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Prevalence and Severity of the Targ
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effect. In the third study, 32 rout
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Table 13.1. Studies of multifaceted
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Table 13.1. Studies of multifaceted
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Table 13.3. Studies of use of dedic
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epidemiology in hospitals: a consen
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140
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Prevalence and Severity of the Targ
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Costs and Implementation The costs
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References 1. Kunin CM, Tupasi T, C
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38. Archer GL. Staphylococcus aureu
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hospital-acquired symptomatic cathe
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Of note, catheters coated with anti
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equiring catheterization for >3 day
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to catheterization via the urethra.
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underlie the development of urethra
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Bergman, 1987 21 Level 1, Level 2 A
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24. Hammarsten J, Lindqvist K. Supr
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then colonize the distal tip. 12,13
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Study Outcomes Both studies evaluat
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Meta-analysis of 12 RCTs (918 patie
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concern. Although there have been n
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Table 16.2.1. Characteristics of tr
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Table 16.2.2. Results of trials com
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venous catheters and to use of CHG
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Table 16.3.2. Results of Studies Co
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14. Sitges Serra A, Puig P, Linares
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48. Maki DG, Ringer M, Alvarado CJ.
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184
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Semi-recumbent positioning Practice
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Potential for Harm There were no si
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References 1. Craven DE, Steger KA.
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significant). The third trial showe
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Opportunities for Impact SDD is not
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Table 17.3.1. Meta-analyses of sele
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digestive tract in critically ill i
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use of H 2 -blockers seems preferab
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Table 17.4.1. Studies of stress ulc
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Section C. Surgery, Anesthesia, and
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quartile to those in the highest wo
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Several of these concerns have been
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Table 18.1. Summary of findings fro
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21. Mennemeyer ST, Morrisey MA, How
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Prevalence and Severity of the Targ
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Because the study relied on surveys
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18. Dashow L, Friedman I, Kempner R
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59. Fowler DL, Hogle N. The impact
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Study Designs and Outcomes As previ
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Table 20.1.1. Meta-analyses examini
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Table 20.1.2. Systematic reviews of
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References 1. Mangram AJ, Horan TC,
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35. Kreter B, Woods M. Antibiotic p
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Study Designs and Outcomes We ident
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4. Kurz A, Kurz M, Poeschl G, Faryn
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Comment Administration of periopera
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Perioperative management of glucose
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intervention group, the number of D
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11. Mowat A, Baum J. Chemotaxis of
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244
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technology. 6,8-10 The non-Doppler
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significance for at least one of th
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Table 21.1. Ultrasound and Doppler
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18. Scherhag A, Klein A, Jantzen J.
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254
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Prevalence and Severity of the Targ
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258
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Opportunities for Impact The FDA ch
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Table 23.1. Evaluations of the FDA
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264
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anesthetic complication, intraopera
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Figure 24.1. ASA standards for basi
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21. Moller JT, Johannessen NW, Espe
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Opportunities for Impact As a relat
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Costs and Implementation The costs
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Table 25.1. Randomized controlled t
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10. Smulyan H, Weinberg SE, Howanit
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Section D. Safety Practices for Hos
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instrumental activities of daily li
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diverse inpatient settings, appropr
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16. Shumway-Cook A, Baldwin M, Poli
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use of a restraint is initiated, wi
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Table 26.2.1. Studies of physical r
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Practice Description A sensor devic
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Study Designs and Outcomes We ident
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Practice Description External hip p
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Table 26.5.1. Hip protectors to pre
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300
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fabricated from elastic polymers) s
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In terms of the feasibility of impl
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with hip fractures in a District Ge
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evidence of dehydration received st
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Table 28.1. Six studies of delirium
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20. Foreman MD. Confusion in the ho
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(eg, limitations in bathing, feedin
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note, the large trial (n=2353) by R
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Table 29.1. Studies of multidiscipl
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References 1. A profile of older Am
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322
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Prevalence and Severity of the Targ
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Comment Reasonable evidence support
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Rubenstei n, 1984 17 123 patients i
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20. Counsell SR, Holder CM, Liebena
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332
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Opportunities for Impact Despite th
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Orthopedic Patients All studies inc
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Trauma Trauma patients, especially
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no prophylaxis, but no difference b
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the most effective means of impleme
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Table 31.2. Summary of DVT risk and
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References 1. US Bureau of the Cens
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34. Green D, Chen D, Chmiel JS. Pre
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Prevalence and Severity of the Targ
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(GFR) or creatinine clearance (CrCl
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Table 32.1. Studies of strategies f
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16. Tepel M, van der Giet M, Schwar
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358
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malnutrition has been defined as a
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10%) in those patients receiving TP
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mortality rates may also have a dim
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References 1. Cerra FB, Benitez MR,
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Chapter 34. Prevention of Clinicall
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The 2000 meta-analysis found no sta
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Table 34.1. Studies evaluating effe
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374
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Chapter 35. Reducing Errors in the
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adiograph misinterpretation. 53 The
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Potential for Harm There is a poten
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10. Goh KY, Tsang KY, Poon WS. Does
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50. Fleisher G, Ludwig S, McSorley
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Prevalence and Severity of the Targ
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overall or in high-risk patients (i
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optimistic assumptions about vaccin
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Table 36.2. 1. Vaccine delivery Stu
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24. Jha P, Deboer D, Sykora K, Nayl
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Chapter 37. Pain Management Erica B
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LoVecchio et al 7 documented change
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References 1. Silen W. Cope’s ear
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fragmentation of care among multipl
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References 1. AHCPR. Acute pain man
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Potential for Harm With placebo, th
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Study Outcomes All studies reported
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References 1. AHCPR Pain Management
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412
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Mixed ICU models—In practice, the
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prognoses, and less futile care for
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Table 38.1. Intensivist management
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References 1. Zimmerman JE, Shortel
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37. Wachter, RM. An introduction to
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Practice Description The availabili
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Level 2 or 3 designs. Mitchell et a
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Comment The studies evaluated in th
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Table 39.1. Measures of nurse staff
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4. 42 inpatient units in one 880- L
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11. Data were collected form Level
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Review article: MEDLINE from Level
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All urinary catheter-patient-days L
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31. Dodd MJ, Dibble SL, Miaskowski
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69. ter Riet G, Kessels AG, Knipsch
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117. Hunt J, Hagen S. Occasional pa
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158. Amaravadi RK, Dimick JB, Prono
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eliability industries have applied
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Subsequently, four Patient Safety C
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unexplored in health care settings,
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‰ All supervisors/managers assist
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21. Vaughn D. The Challenger Launch
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Section G. Systems Issues and Human
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Manufacturing Practice Regulation,
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Ongoing Device Evaluation Devices a
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cases, with subjects serving as the
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motion-detection testing to the ide
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12. Brown SL, Bogner MS, Parmentier
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52. Cooper JB, Newbower RS, Long CD
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no controlled studies are currently
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group and the loss to follow-up gro
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13. Dvorak SR, McCoy RA, Voss GD. C
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Potential for Harm The study report
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Prevalence and Severity of the Targ
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6. Rawal J, Barnett P, Lloyd BW. Us
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The primary outcome was adherence w
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Final Comment to Chapter 42 Faulty
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procedure or treatment can occur un
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donor having blood group compatibil
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The limitations of these studies ar
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23. Arenson RL, London JW. Comprehe
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period 3 times longer. 13 This sugg
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Comment While “signing the site
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500
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level, CRM includes training on how
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Comparison to Medicine Sexton and c
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training methods with reviews of li
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4. Cooper GE, White MD, Lauber JK.
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510
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follow-up) by which performance is
- Page 524 and 525:
a 30-day period. At the end of the
- Page 526 and 527:
4. Dunn D. Malignant hyperthermia.
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45. Champagne MT, Harrell JS, Fried
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alert and at some point general per
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performance are in non-medical sett
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inventory assessed at one-month fol
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effects, addiction, and performance
- Page 538 and 539:
34. Majidian AM, Brinker MR, Rice J
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76. Tucker P, Smith L, Macdonald I,
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116. Bruck D, Pisani DL. The effect
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Chapter 47. Safety During Transport
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sickness and intensity of therapy c
- Page 548 and 549:
Subchapter 47.2. Intrahospital Tran
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Table 47.1. Specialized transport t
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References 1. Pollack MM, Alexander
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Section H. Role of the Patient Chap
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Chapter 48. Procedures For Obtainin
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forms, and benefits appeared in 37%
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done, list complications, and state
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8-item knowledge examination coveri
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22. Hopper KD, TenHave TR, Tully DA
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Chapter 49. Advance Planning For En
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was inconsistent with their previou
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Administrative Initiatives to Ascer
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hours prior to death (57% vs. 75%).
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Figure 49.1. POLST Wallet Card inst
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18. Donaldson M, Field, MJ. Measuri
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568
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medical mistakes. 17 Dr. Robert Arn
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14. Robinson JL, Nash DB. Consumers
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574
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Study Design There are no well-desi
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Potential for Harm It has been theo
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21. Smith WR. Evidence for the effe
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Study Design There is a dearth of w
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effect of a pathway on the treatmen
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References 1. Every NR, Hochman J,
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588
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Prevalence and Severity of the Targ
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dosing, and more significantly, 4 o
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10. Walton R, Dovey S, Harvey E, Fr
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eceive appropriate care. 6, 7 Physi
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Costs and Implementation Although t
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References 1. Smith WR. Evidence fo
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their effect on patient safety is l
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administration. 24, 25 It is antici
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Table 55.1. New JCAHO safety standa
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References 1. Kohn LT, Corrigan JM,
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610
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612
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function of the prevalence and seve
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concern for harm based on the level
- Page 628 and 629:
Chapter 57 summarizes the overall r
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Table 57.1. Patient Safety Practice
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Table 57.3 Patient Safety Practices
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Table 57.4 Patient Safety Practices
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626
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12 Hospital-acquired infections Imp
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Table 58.2 Further Research Likely
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632
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Ch. # Patient Safety Target Patient
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Ch. # Patient Safety Target Patient
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Ch. # Patient Safety Target 37.4 In
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Ch. # Patient Safety Target 47 Adve
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15 Unclear effect size due to mixed
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42 Insufficient information about r
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69 Most evidence available outside
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648
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Contributors Joseph V. Agostini, MD
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Harvey J. Murff, MD Fellow, Divisio
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654
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calorimetry, 359 Candida species in
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studies, 88, 92 high reliability th
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acute pain services, studies, 404,
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transurethral resection of the pros