Conference PPT (5 MB) - Institute for Oral Health
Conference PPT (5 MB) - Institute for Oral Health
Conference PPT (5 MB) - Institute for Oral Health
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Johnson JT,et al. <strong>Oral</strong> pilocarpine in post-irradiation xerostomia in patients<br />
with head and neck cancer. New Engl J Med, 329:390, 1993<br />
Prescription Medications<br />
• Pilocarpine<br />
(Salagen®)<br />
– 5 mg. tid (not to<br />
exceed 30 mg/day)<br />
– Treat <strong>for</strong> minimum<br />
of 90 days<br />
– Contraindications:<br />
Asthma, glaucoma<br />
– Side effects:<br />
sweating<br />
• Cevimeline<br />
(Evoxac)<br />
– 30-60 mg. Tid (not<br />
to exceed 180<br />
mg/day)<br />
– Contraindications:<br />
asthma, glaucoma,<br />
severe COPD<br />
– Side effects:<br />
sweating
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