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cancer.uchicago.edu VOL. 4, ISSUE 10 OCTOBER 2011<br />
Find Us on<br />
Facebook<br />
and Twitter<br />
Funding Opportunities<br />
Funding opportunities for cancer<br />
research with internal or agency<br />
deadlines from Oct. 11–Nov. 10:<br />
UCCCC<br />
• American Cancer Society<br />
Institutional Research Grant<br />
Request for Applications from<br />
Junior Faculty<br />
American Cancer Society<br />
• Mentored Research Scholarship<br />
Grants in Applied and Clinical<br />
Research<br />
• Research Scholar Grants in<br />
Cancer Control: Health Policy<br />
and Health Services Research<br />
American Lung Association<br />
• Clinical Patient Care Research<br />
Grant<br />
• Biomedical Research Grant<br />
Leukemia and Lymphoma Society<br />
• Specialized Center <strong>of</strong> Research<br />
Award<br />
Melanoma Research Foundation<br />
• Career Development Award<br />
National Institutes <strong>of</strong> Health<br />
• Translational Scholar Career<br />
Awards in Pharmacogenomics<br />
and Personalized <strong>Medicine</strong><br />
• NIH Director’s New Innovator<br />
Award Program<br />
Pancreatic Cancer Action Network<br />
• Pathway to Leadership Grant<br />
• Fellowship Awards<br />
For a complete listing, visit the<br />
Funding Opportunities section <strong>of</strong> the<br />
UCCCC website.<br />
<strong>Member</strong> <strong>News</strong> & <strong>Updates</strong><br />
Salgia to Enhance Translational<br />
<strong>Medicine</strong> at U<strong>Chicago</strong><br />
Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> Ravi Salgia, MD, PhD, has been named<br />
the associate director for translational science for the UCCCC<br />
and the new vice chair for<br />
translational research for the<br />
Department <strong>of</strong> <strong>Medicine</strong> (DOM)<br />
to bolster U<strong>Chicago</strong>’s cancer<br />
research and translational<br />
medicine programs. His<br />
responsibilities as vice chair<br />
for translational research will<br />
include: helping recruit translational researchers; promoting<br />
translational research across the DOM; reorganizing the DOM<br />
Research Advisory Committee; and facilitating the development<br />
<strong>of</strong> new scientific programs. As the new associate director for<br />
translational science for the UCCCC, Dr. Salgia will work closely<br />
with UCCCC leaders to promote translational research within<br />
the UCCCC and across <strong>The</strong> <strong>University</strong> <strong>of</strong> <strong>Chicago</strong> Medical Center<br />
cancer programs.<br />
Artz, Zimmerman Serve as Interim<br />
Transplant Program Directors<br />
Andrew Artz, MD, assistant pr<strong>of</strong>essor <strong>of</strong> medicine, has<br />
assumed responsibilities as interim director <strong>of</strong> the Bone Marrow<br />
Transplant (BMT) Program<br />
and will have oversight<br />
and responsibility for all<br />
clinical, administrative,<br />
and research aspects <strong>of</strong><br />
the program. Dr. Artz<br />
is joined by Associate<br />
Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong> Todd<br />
From left: Andrew Artz, MD, Todd Zimmerman, MD<br />
Zimmerman, MD, who<br />
will assume responsibilities<br />
as interim director <strong>of</strong> Autologous Blood and Marrow<br />
Transplantation. In this role, Dr. Zimmerman will work closely<br />
with Dr. Artz to supervise and enhance autologous transplant<br />
activities.<br />
Continued on Page 2<br />
At the Forefront <strong>of</strong> Discovery ®
<strong>Member</strong> <strong>News</strong> OCTOBER 2011<br />
Continued from Page 1<br />
Armato Selected for Research<br />
Fellowship in Japan<br />
Samuel Armato, PhD, associate<br />
pr<strong>of</strong>essor <strong>of</strong> radiology, was invited<br />
by the Japanese Society for the<br />
Promotion <strong>of</strong> Science to visit Japan<br />
as a research fellow for 2 weeks in<br />
March. He will travel to five Japanese<br />
universities to deliver lectures on his<br />
research, including his leadership<br />
with the National Cancer Institutefunded<br />
Lung Image Database Consortium <strong>of</strong> thoracic<br />
CT scans with nodules. During his visits, he will also<br />
provide guidance to the Japanese research groups on<br />
their research methodology.<br />
Weichselbaum Earns Award<br />
Ralph Weichselbaum, MD,<br />
pr<strong>of</strong>essor <strong>of</strong> radiation and<br />
cellular oncology, and colleagues<br />
have received $50,000 from<br />
U<strong>Chicago</strong>Tech’s Innovation Fund<br />
to validate the gene signature<br />
that predicts individual benefit<br />
from radiation therapy for early<br />
stage, localized breast cancer. <strong>The</strong><br />
Innovation Fund, which supports pro<strong>of</strong>-<strong>of</strong>-concept<br />
projects, will allow Dr. Weichselbaum and colleagues<br />
to potentially develop a test that can identify which<br />
patients will benefit from radiation and chemotherapy<br />
for many types <strong>of</strong> cancer, including head and neck,<br />
breast, lung, prostate, and high-grade glioma.<br />
Olopade Delivers Distinguished<br />
Lecture on Cancer Health<br />
Disparities<br />
<strong>The</strong> American Association for Cancer Research<br />
(AACR) awarded Olufunmilayo Olopade, MBBS,<br />
Walter L. Palmer Distinguished<br />
Service Pr<strong>of</strong>essor <strong>of</strong> <strong>Medicine</strong><br />
and Human Genetics, with the<br />
2011 AACR Distinguished Lecture<br />
on the Science <strong>of</strong> Cancer Health<br />
Disparities, funded by Susan G.<br />
Komen for the Cure®. A member<br />
<strong>of</strong> the Komen Scholars scientific<br />
advisory panel, Dr. Olopade was<br />
honored for her work in the study<br />
<strong>of</strong> breast cancer genetics. She delivered a lecture,<br />
“Closing the Knowledge Disparity Gap: From Molecular<br />
Mechanisms to Interventions and Back,” during the<br />
AACR Conference on <strong>The</strong> Science <strong>of</strong> Cancer Health<br />
Disparities, held Sept. 18-21 in Washington, D.C.<br />
Welcome, Newly Hired Faculty<br />
<strong>The</strong> UCCCC is proud to have the following individuals join<br />
our efforts to diagnose, treat, and prevent cancer.<br />
<strong>Member</strong> <strong>News</strong><br />
Vol. 4, Issue 10 October 2011<br />
<strong>The</strong> UCCCC’s monthly <strong>Member</strong> <strong>News</strong><br />
e-newsletter features recent accomplishments<br />
and member highlights. It also showcases<br />
services and tools <strong>of</strong>fered by the UCCCC<br />
and provides information on upcoming<br />
seminars, events, and funding and educational<br />
opportunities.<br />
To submit a story, e-mail feedback@bsd.uchicago.edu<br />
or call 1-773-702-2806.<br />
Find Us on<br />
Facebook<br />
and Twitter<br />
Jonas de Souza, MD, is an instructor <strong>of</strong> medicine<br />
in the Section <strong>of</strong> Hematology/Oncology.<br />
His research focuses on malignancies <strong>of</strong> the upper<br />
aerodigestive tract, especially head and neck<br />
cancers.<br />
Hongtao Liu, MD, PhD, joined the Section<br />
<strong>of</strong> Hematology/Oncology as an instructor. His<br />
research efforts focus on therapeutic strategies<br />
for acute myeloid leukemia, stem cell transplantation,<br />
and other hematological malignancies.<br />
Gordana Raca, MD, PhD, joins Michelle M. Le<br />
Beau, PhD, as a co-director <strong>of</strong> the Cancer Cytogenetics<br />
Laboratory. Dr. Raca’s research includes<br />
molecular and cytogenetic mechanisms <strong>of</strong> genetic<br />
diseases and diagnostics.<br />
cancer.uchicago.edu 2
<strong>Member</strong> <strong>News</strong> OCTOBER 2011<br />
FOCUS ON<br />
CORE FACILITIES<br />
MRIS<br />
<strong>The</strong> Magnetic Resonance<br />
Imaging and Spectroscopy<br />
Facility (MRIS) utilizes a 9.4T<br />
scanner to provide highquality<br />
MR images and<br />
analyzation techniques for studies <strong>of</strong> both animal models<br />
and clinical research involving human subjects.<br />
Services Provided:<br />
• Scans <strong>of</strong> tissues, cells, materials, animal models <strong>of</strong><br />
cancer, and patients to provide information such as<br />
detailed 3D anatomy, blood volume, energy<br />
metabolism, changes in tumor oxygenation during<br />
therapy, calcium dynamics, and pancreatic function<br />
• Development and functional MR imaging (fMRI)<br />
measurements <strong>of</strong> the brain<br />
• Molecular imaging and correlation with gene<br />
expression<br />
• Multimodality imaging including optical, micropositron<br />
emission tomography (microPET)/single<br />
photon emission computed tomography (SPECT)/CT<br />
and electron paramagnetic resonance (EPR)<br />
• Development and testing <strong>of</strong> new contrast agents and<br />
imaging methods<br />
• Data analysis and consultation<br />
• Veterinary services, including the preparation <strong>of</strong><br />
animals for MRI experiments, anesthesia and<br />
respiration, physiological monitoring, catheter<br />
implantation, and tumor implantation<br />
• MRI components <strong>of</strong> clinical trials ( e.g., use <strong>of</strong> MRI to<br />
evaluate response to experimental therapies)<br />
To learn more about the MRIS Core Facility, visit<br />
mris.bsd.uchicago.edu.<br />
Upcoming Seminars<br />
Tuesday, Oct. 4<br />
4:00–5:00 p.m., KCBD 1103<br />
<strong>The</strong> <strong>University</strong> <strong>of</strong> <strong>Chicago</strong> Breast Cancer SPORE<br />
Breast Tissue Composition and Susceptibility to Breast Cancer<br />
Norman F. Boyd, MD, pr<strong>of</strong>essor <strong>of</strong> medicine<br />
<strong>University</strong> <strong>of</strong> Toronto<br />
Monday, Oct. 10<br />
7:30 a.m.–2:30 p.m., Gleacher Center, 450 N. Cityfront Plaza Dr.<br />
<strong>The</strong> <strong>University</strong> <strong>of</strong> <strong>Chicago</strong> Department <strong>of</strong> <strong>Medicine</strong><br />
<strong>The</strong> Inaugural Francis L. Lederer Foundation Symposium on<br />
Esophageal Cancer Research<br />
Friday, Oct. 21<br />
12:00–1:00 p.m., KCBD 1103<br />
UCCCC Seminar Series<br />
Cancer and Aging: Rival Demons<br />
Judith Campisi, PhD, pr<strong>of</strong>essor <strong>of</strong> cell & molecular biology<br />
Lawrence Berkeley National Laboratory, <strong>University</strong> <strong>of</strong> California<br />
Pritzker School <strong>of</strong><br />
<strong>Medicine</strong> Receives<br />
High Rankings<br />
Congratulations to <strong>The</strong><br />
<strong>University</strong> <strong>of</strong> <strong>Chicago</strong> Pritzker<br />
School <strong>of</strong> <strong>Medicine</strong> for being<br />
ranked #5 in the U.S. <strong>News</strong> &<br />
World Report’s Best Graduate<br />
Schools survey. Pritzker also<br />
ranked #12 in the Medical<br />
Research category.<br />
SAVE THE DATE<br />
Monday, May 21<br />
Shubitz Lecture<br />
<strong>The</strong> prestigious 2012 Simon M. Shubitz Cancer Prize will be bestowed<br />
upon Joe Gray, PhD, a renowned genomics expert at Oregon Health<br />
& Science <strong>University</strong>’s Knight Cancer Institute, who is taking a lead on<br />
making personalized cancer medicine a reality for all patients.<br />
cancer.uchicago.edu 3
<strong>Member</strong> <strong>News</strong> OCTOBER 2011<br />
Upcoming Activities<br />
October 4, 14, and 25<br />
ED-U-CATE Sessions<br />
Exelon, Catholic Charities, and<br />
<strong>Chicago</strong> Public Schools<br />
October 14<br />
ENRICH’D Program<br />
Percy L. Julian High School<br />
<strong>The</strong> OCECD will help students<br />
develop a prostate cancer<br />
screening campaign<br />
October 17<br />
ENRICH’D Town Hall Meeting<br />
on Breast Cancer<br />
Chinese American Service<br />
League<br />
Breast cancer screening education<br />
delivered in Cantonese<br />
and mammography sign-ups<br />
Clockwise from top left: NASCAR driver Max Papis brightens the day for Danita Williams, a survivor<br />
<strong>of</strong> uterine cancer; <strong>University</strong> <strong>of</strong> <strong>Chicago</strong> Pritzker School <strong>of</strong> <strong>Medicine</strong> student David Bluhm<br />
administers a flu shot to a soccer player at the “¡Gol...A Tú Salud!” health fair; Pamela Cratic,<br />
Arlean Pleasant, and Dr. Deborah Beasley get ready to watch an advance screening <strong>of</strong> the<br />
movie “50/50,” presented by the UCCCC and LIVESTRONG; Ursula Redmond, OCECD program<br />
outreach manager, and OCECD Director Karen Kim, MD, MS, are thanked by members <strong>of</strong><br />
the Army Reserve Teen Panel after Dr. Kim spoke to the group about cancer prevention.<br />
October 25<br />
Cancer Transitions<br />
Apostolic Faith Church<br />
A program for cancer survivors<br />
developed by LIVESTRONG<br />
<strong>News</strong> from the<br />
OCECD<br />
<strong>The</strong> UCCCC Office <strong>of</strong> Community<br />
Engagement and Cancer Disparities<br />
(OCECD) serves local communities<br />
through research, education, and<br />
outreach programs. In this section,<br />
we highlight recent and upcoming<br />
OCECD activities. Visit cancer.<br />
uchicago.edu/community for more<br />
information.<br />
Recent Activities<br />
NASCAR Driver Visits Cancer<br />
Survivors<br />
Massimiliano “Max” Papis,<br />
NASCAR’s first Italian driver, visited<br />
U<strong>Chicago</strong> in September as an<br />
ambassador from LIVESTRONG,<br />
the Lance Armstrong Foundation.<br />
He ate lunch with four adult cancer<br />
survivors and spent time with<br />
pediatric cancer patients during<br />
their infusion treatments. He also<br />
shared his personal experiences<br />
with cancer and donated a steering<br />
wheel to U<strong>Chicago</strong>’s sports<br />
memorabilia collection.<br />
Army Reserve Teen Leaders<br />
Learn About Cancer Prevention<br />
In September, OCECD Director<br />
Karen E. Kim, MD, MS, associate<br />
pr<strong>of</strong>essor <strong>of</strong> medicine, met with 21<br />
teens from the U.S. Army Reserve<br />
Teen Panel to discuss cancer<br />
prevention. <strong>The</strong> teens were children<br />
<strong>of</strong> Army reservists who have been<br />
selected from all over the country<br />
to develop effective strategies and<br />
implement solutions for issues they<br />
face as military youth.<br />
Health Fair Promotes Cancer<br />
Awareness for Hispanics<br />
<strong>The</strong> OCECD and the American<br />
Cancer Society hosted a health<br />
fair, “¡Gol...A Tú Salud!” (Goal...<br />
To Your Health!), at Luther South<br />
High School in September during<br />
the <strong>Chicago</strong> Latin American Soccer<br />
Association’s championship games,<br />
attended by nearly 3,000 people<br />
that weekend. Visitors to OCECD’s<br />
tent were <strong>of</strong>fered blood pressure<br />
screenings, fresh fruit and water, as<br />
well as information about cancer<br />
screening services. Additionally,<br />
students from Pritzker School <strong>of</strong><br />
<strong>Medicine</strong> helped administer 163<br />
flu shots provided by the <strong>Chicago</strong><br />
Department <strong>of</strong> Public Health.<br />
<strong>The</strong> event coincided with Prostate<br />
Cancer Awareness Month and<br />
Hispanic Heritage Month.<br />
cancer.uchicago.edu 4
<strong>Member</strong> <strong>News</strong> OCTOBER 2011<br />
<strong>Member</strong>s in the Media<br />
<strong>The</strong> following news stories feature UCCCC members.<br />
To submit a story, e-mail feedback@bsd.uchicago.edu.<br />
Mark Ratain, MD, provided commentary in <strong>The</strong><br />
Cancer Letter about the possibility <strong>of</strong> creating a nonpr<strong>of</strong>it<br />
drug company to alleviate drug shortages.<br />
(UCCCC members have free access to this newsletter.<br />
Contact feedback@bsd.uchicago.edu for information.)<br />
Dr. Ratain also received coverage in New Drugs Info<br />
magazine about a commentary he wrote for the Journal<br />
<strong>of</strong> Clinical Oncology speaking out against oral cancer<br />
drugs being taken without food.<br />
Kenneth Alexander, MD, PhD, was quoted in<br />
New York magazine for a story about Rep. Michele<br />
Bachmann’s (R-Minn.) comment that suggested a<br />
link between the human papilloma virus vaccine and<br />
mental retardation. He warned that misled parents<br />
could avoid getting their daughters immunized, putting<br />
them at risk for developing cervical cancer.<br />
During September, which is Leukemia and Lymphoma<br />
Awareness Month, the <strong>Chicago</strong> Blood Cancer<br />
Foundation posted an episode <strong>of</strong> “Battling and Beating<br />
Cancer” with Michelle Le Beau, PhD, who discussed<br />
progress in treating leukemia and in understanding the<br />
biology <strong>of</strong> the disease.<br />
Richard Schilsky, MD, commented in a Medscape<br />
Medical <strong>News</strong> article about the American Association<br />
for Cancer Research’s cancer progress report that<br />
urges Congress to continue to increase funding for<br />
biomedical research.<br />
Susan Cohn, MD, was mentioned or quoted in several<br />
news clips this month:<br />
<strong>The</strong> Daily Herald reported about a H<strong>of</strong>fman Estates<br />
family that donated 100% <strong>of</strong> its proceeds from a 5K<br />
run to help neuroblastoma research led by Dr. Cohn at<br />
Comer Children’s Hospital.<br />
Dr. Cohn was featured in the “Conversations with...”<br />
video series by MedPage Today about progress made<br />
over the past several decades in pediatric oncology.<br />
Dr. Cohn received coverage in a <strong>Chicago</strong> Health<br />
story about an 8-year-old cancer survivor whose<br />
neuroblastoma was treated at Comer with<br />
immunotherapy.<br />
U<strong>Chicago</strong> in the Media<br />
<strong>The</strong> Daily Herald reported on an event held by TV<br />
celebrity Dina Manzo’s charity fund, Atia’s Project<br />
Ladybug, to raise money to support pediatric cancer<br />
patients and their families at Comer Children’s<br />
Hospital. <strong>The</strong> event featured a life-sized Candy Land<br />
game and raised $8,500.<br />
Comer received coverage in a Berwyn Life article<br />
about a 7-year-old girl undergoing treatment for<br />
medulloblastoma.<br />
<strong>The</strong> Daily Herald described the Libertyville High<br />
School football coach’s experiences with cancer during<br />
his last season before retirement. <strong>The</strong> coach was treated<br />
with radiation and chemotherapy at U<strong>Chicago</strong> for<br />
squamous cell carcinoma.<br />
U<strong>Chicago</strong> received coverage in Health Day <strong>News</strong> for a<br />
tailored hepatitis C therapy that may halve the length<br />
<strong>of</strong> treatment.<br />
<strong>The</strong> Elmhurst Patch wrote a story about a group <strong>of</strong> third<br />
graders that organized a lemonade stand to help their<br />
classmate who is being treated for neuroblastoma at<br />
U<strong>Chicago</strong>.<br />
U<strong>Chicago</strong> was mentioned in the Winston-Salem<br />
Journal as one <strong>of</strong> the participating sites <strong>of</strong> a clinical trial<br />
for a neo-urinary conduit implanted in patients with<br />
bladder cancer.<br />
<strong>The</strong> <strong>Chicago</strong> Tribune covered a story about the long<br />
political career <strong>of</strong> U.S. Representative Bobby Rush<br />
(D-Ill.), mentioning that he was treated by U<strong>Chicago</strong><br />
doctors for cancer <strong>of</strong> the salivary gland.<br />
A photo <strong>of</strong> a U<strong>Chicago</strong> physician using the da Vinci<br />
Surgical System was featured in a Columbia Daily<br />
Tribune article about early detection <strong>of</strong> prostate cancer.<br />
<strong>The</strong> <strong>Chicago</strong> Tribune reported on U<strong>Chicago</strong>’s plans<br />
to help fund the new James C. Tyree Charitable<br />
Foundation in memory <strong>of</strong> the Sun-Times chairman who<br />
was passionate about healthcare.<br />
Science Daily reported on a study by U<strong>Chicago</strong><br />
physician Navin Pinto, MD, that found common genetic<br />
variants were linked to high-risk neuroblatoma.<br />
cancer.uchicago.edu 5