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<strong>Div<strong>in</strong>g</strong> <strong>Medic<strong>in</strong>e</strong> <strong>in</strong> <strong>Malaysia</strong><br />

Lt Kol (Dr) Halim Mohamed<br />

Institute <strong>of</strong> Underwater <strong>and</strong> Hyperbaric <strong>Medic<strong>in</strong>e</strong><br />

Armed Forces Hospital Lumut<br />

1


Scope<br />

• Introduction<br />

• Development <strong>of</strong> IUHM<br />

• Decompression Illness (DCI) <strong>in</strong> <strong>Malaysia</strong><br />

– Demography<br />

– Presentation<br />

– Treatment <strong>and</strong> Outcomes<br />

• Conclusion<br />

2


Decompression Illness<br />

6


Cerebral Arterial Gas Embolism (CAGE)<br />

8


CAGE<br />

• Symptoms usually start dur<strong>in</strong>g or<br />

immediately after surfac<strong>in</strong>g (85% < 5<br />

m<strong>in</strong>utes <strong>of</strong> surfac<strong>in</strong>g)<br />

• Symptoms<br />

– LOC<br />

– Paralysis or weakness<br />

– Numbness<br />

– Dizz<strong>in</strong>ess<br />

– Blurred vision<br />

– Disorientation<br />

– +/- symptoms <strong>of</strong> Pneumothorax,<br />

Pneumomediast<strong>in</strong>um, Subcutaneous<br />

Emphysema<br />

9


Henry’s s Law<br />

<strong>The</strong> amount <strong>of</strong> gas that will dissolve <strong>in</strong> a liquid<br />

is directly proportional to the partial pressure <strong>of</strong> that gas.<br />

pN 2<br />

pN 2<br />

pN 2<br />

pN 2<br />

pN 2<br />

<strong>in</strong>gass<strong>in</strong>g<br />

pN 2<br />

pN 2<br />

Equilibrium (Saturation)<br />

pN 2<br />

Outgass<strong>in</strong>g<br />

(supersaturation)<br />

12


Decompression Sickness (DCS)<br />

• <strong>The</strong> formation <strong>of</strong> <strong>in</strong>ert gas bubbles <strong>in</strong> blood <strong>and</strong> body<br />

tissues when a diver returns to a lower pressure<br />

environment.<br />

13


DCS - Pathophysiology<br />

• Direct bubble effects<br />

– blockage - tissue hypoxia, venous<br />

congestion, direct pressure,<br />

• Indirect bubble effects<br />

– leaky capillaries, sludg<strong>in</strong>g, , activation <strong>of</strong><br />

platelets, coagulation, fat emboli from<br />

damaged tissues, histam<strong>in</strong>e release.<br />

14


DCS – Symptoms <strong>and</strong> Signs<br />

• 90% with<strong>in</strong> 15 m<strong>in</strong>utes to 12 hours after surfac<strong>in</strong>g<br />

• Symptoms <strong>and</strong> Signs<br />

– Pa<strong>in</strong>, <strong>in</strong> the jo<strong>in</strong>ts <strong>of</strong> arms, legs or trunk<br />

– Paralysis or Weakness<br />

– Numbness or paraesthesia<br />

– Tiredness, Nausea, Headache, Dizz<strong>in</strong>ess, Unusual Fatigue<br />

– Rash & Itch<strong>in</strong>g<br />

– Chest tightness or shortness <strong>of</strong> breath<br />

– LOC, altered level <strong>of</strong> consciousness.<br />

– Loss <strong>of</strong> balance<br />

– Change <strong>in</strong> Personality<br />

– Visual disturbance, Speech disturbance<br />

– Convulsions<br />

– Hear<strong>in</strong>g Loss / T<strong>in</strong>nitus<br />

– SOB, Haemoptysis<br />

16


17<br />

Loss <strong>of</strong> consciousness<br />

Headache<br />

Fatigue<br />

Ur<strong>in</strong>ary retention<br />

Visual symptoms<br />

Shortness <strong>of</strong> breath<br />

Rash/Itch<br />

Convulsions<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Symptoms <strong>and</strong> Signs<br />

(Source: Institute <strong>of</strong> Underwater <strong>and</strong> Hyperbaric <strong>Medic<strong>in</strong>e</strong> Jan 1996-Dec 2004)<br />

Numbness/Paraesthesia<br />

Pa<strong>in</strong><br />

Weakness/Paralysis<br />

Dizz<strong>in</strong>ess/Vertigo/Nausea/Vomit<strong>in</strong>g<br />

Number <strong>of</strong> Cases


Oxygen Recompression <strong>The</strong>rapy<br />

• Mechanism:<br />

– Decrease bubble size (Boyle’s s Law)<br />

– Hasten nitrogen elim<strong>in</strong>ation (Henry’s s Law)<br />

– Increase oxygenation to hypoxic areas<br />

– Reduces secondary bubble effects<br />

20


Dept <strong>of</strong> <strong>Div<strong>in</strong>g</strong> <strong>and</strong> Hyperbaric <strong>Medic<strong>in</strong>e</strong><br />

21


Demography<br />

(N=159)<br />

DCI cases treated at Dept <strong>of</strong> <strong>Div<strong>in</strong>g</strong> <strong>Medic<strong>in</strong>e</strong>, AFH Lumut<br />

between 1st October 1996 <strong>and</strong> 31st December 2003<br />

25


Incidence<br />

50<br />

45<br />

40<br />

35<br />

30<br />

Cases<br />

25<br />

20<br />

15<br />

1<br />

5<br />

1<br />

45<br />

2<br />

10<br />

5<br />

17<br />

20<br />

1<br />

7<br />

21<br />

16<br />

1<br />

11<br />

4<br />

7<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003<br />

Year<br />

Arterial Gas Embolism<br />

Decompression illness<br />

26<br />

(Source: IUHM Jan 1996 - Dec 2003)


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

0 - 33<br />

27


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

Dive:<br />

Depth (m) 28.3 (17.5)<br />

No <strong>of</strong> dives<br />

Dive Pr<strong>of</strong>ile<br />

2 (median)<br />

Non-Provocative: 56 (35)%<br />

Provocative: 103 (65%)<br />

0 - 33<br />

5 – 75<br />

1 - 10<br />

28


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

Dive:<br />

Depth (m) 28.3 (17.5)<br />

No <strong>of</strong> dives<br />

Dive Pr<strong>of</strong>ile<br />

Delay to Initial Emergency<br />

Treatment (hours)<br />

2 (median)<br />

Non-Provocative: 56 (35)%<br />

Provocative: 103 (65%)<br />

3.3 (2.7)<br />

Delay to Recompression (hours) 12.3 (9.7)<br />

0 - 33<br />

5 – 75<br />

1 - 10<br />

1 - 12<br />

5 – 48<br />

29


Incidence<br />

Commercial -<br />

Others<br />

13%<br />

21 8<br />

Military<br />

5%<br />

75 55<br />

Commercial - UW<br />

Loggers<br />

47%<br />

Recreational<br />

35%<br />

30


Underwater Logg<strong>in</strong>g<br />

32


Convulsions<br />

Rash/Itch<br />

33<br />

Shortness <strong>of</strong> breath<br />

Headache<br />

Fatigue<br />

Ur<strong>in</strong>ary retention<br />

Visual symptoms<br />

Loss <strong>of</strong> consciousness<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Symptoms <strong>and</strong> Signs<br />

N = 158<br />

Numbness/Paraesthesia<br />

Pa<strong>in</strong><br />

Weakness/Paralysis<br />

Dizz<strong>in</strong>ess/Vertigo/Nausea/Vomit<strong>in</strong>g<br />

Number <strong>of</strong> Cases


Sp<strong>in</strong>al/Cerebral<br />

Symptoms <strong>and</strong> Signs<br />

Cerebral<br />

32%<br />

Miss<strong>in</strong>g<br />

Neurological (66%)<br />

N = 158<br />

9%<br />

Periph<br />

1%<br />

Sp<strong>in</strong>al<br />

57%<br />

94<br />

51<br />

3<br />

Musculoskeletal (32%)<br />

CVS / RS (2%)<br />

Miss<strong>in</strong>g<br />

4.8%<br />

Others<br />

9.5%<br />

Site <strong>of</strong> Pa<strong>in</strong><br />

Upper Limb<br />

23.8%<br />

Sp<strong>in</strong>e/Trunk<br />

33.3%<br />

Lower Limb<br />

34<br />

28.6%


Treatment Outcomes<br />

Mild Residual<br />

Symptoms<br />

17%<br />

Severe<br />

Residual<br />

Symptoms<br />

15%<br />

27<br />

23<br />

108<br />

Full Recovery<br />

68%<br />

35


Other Complications<br />

• Cranial diabetes <strong>in</strong>sipidus (3 cases)<br />

• Lobar pneumonia (2 cases)<br />

• Pulmonary oxygen toxicity - nil<br />

36


Residual Paraplegia / Paraparesis<br />

Results<br />

37


Outcomes<br />

SEVERE RESIDUAL DEFICITS<br />

(N=14)<br />

Results<br />

Residual Numbness/P<br />

16.7%<br />

Res Ur<strong>in</strong>ary Incont<strong>in</strong><br />

16.7%<br />

Residual Paralysis<br />

66.7%<br />

39


DCI Incidence <strong>and</strong> Mortality Rates<br />

• Oil rig divers <strong>of</strong> Gulf <strong>of</strong> Mexico:<br />

– Incidence <strong>of</strong> DCI:<br />

• 9.6 per 100,000 dives<br />

– <strong>Div<strong>in</strong>g</strong> Deaths:<br />

• 2.49 per 1000 diver per year.<br />

• UW Loggers <strong>in</strong> Tasik B<strong>and</strong><strong>in</strong>g:<br />

– Incidence <strong>of</strong> DCI:<br />

• 76 cases for 5-yr 5<br />

period Jan<br />

97-Dec 02<br />

• = 15.2 cases / yr<br />

• = 27.8 per 100,000 dives*<br />

– <strong>Div<strong>in</strong>g</strong> deaths:<br />

• 6 cases for 5-yr 5<br />

period Jan 97-<br />

Dec 02<br />

• = 20 deaths per 1000 diver per<br />

year*<br />

*Based on 2.5 dives / diver / day; 60 work<strong>in</strong>g 42 divers<br />

each day at Tasik B<strong>and</strong><strong>in</strong>g throughout the year.


Workplace Assessment<br />

• All untra<strong>in</strong>ed divers<br />

• Inappropriate div<strong>in</strong>g equipment<br />

• Inappropriate div<strong>in</strong>g techniques /<br />

procedures<br />

• No oxygen / safety equipment / first aid<br />

equipment on board<br />

• <strong>Div<strong>in</strong>g</strong> at Altitude 1300ft ASL<br />

• Repetitive, multi-day div<strong>in</strong>g<br />

• Strenuous dives<br />

• Cold water temperatures<br />

43


Workplace Assessment<br />

44


Prevention<br />

45


Tra<strong>in</strong><strong>in</strong>g<br />

46


Tra<strong>in</strong><strong>in</strong>g<br />

47


Medical Assessment Prior to <strong>Div<strong>in</strong>g</strong><br />

800<br />

700<br />

668 656<br />

Jumlah Pemeriksaan<br />

Activities<br />

600<br />

500<br />

400<br />

300<br />

200<br />

328<br />

452<br />

534<br />

408<br />

547<br />

502<br />

545<br />

100<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003 2004<br />

Tahun<br />

Source: IUHM Annual Returns Nov 1996 - Dec 2004<br />

48


Medical Assessment Prior to <strong>Div<strong>in</strong>g</strong><br />

800<br />

700<br />

668 656<br />

Jumlah Pemeriksaan<br />

Activities<br />

600<br />

500<br />

400<br />

300<br />

200<br />

328<br />

452<br />

534<br />

408<br />

547<br />

502<br />

545<br />

100<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003 2004<br />

Tahun<br />

Source: IUHM Annual Returns Nov 1996 - Dec 2004<br />

49


Field Medical Support for <strong>Div<strong>in</strong>g</strong> Ops<br />

50


<strong>Malaysia</strong>n <strong>Div<strong>in</strong>g</strong> Emergency Hotl<strong>in</strong>e<br />

51


Wound Cl<strong>in</strong>ic<br />

Hyperbaric Chamber<br />

<strong>Department</strong> <strong>of</strong> <strong>Div<strong>in</strong>g</strong> <strong>and</strong> Hyperbaric <strong>Medic<strong>in</strong>e</strong><br />

Compressor, Air Banks, Air Dryers <strong>and</strong> Filters<br />

LOX<br />

58


Submar<strong>in</strong>e <strong>Medic<strong>in</strong>e</strong><br />

60


0.5 ATM<br />

Pressure<br />

6000 m<br />

62


Cerebral Arterial Gas Embolism<br />

(CAGE)<br />

63


Boyle’s s Law<br />

“Pressure is <strong>in</strong>versely<br />

related to Volume”<br />

P ∝ 1/V<br />

P1V1 = P2V2<br />

64


Barotrauma<br />

• Damage to tissues <strong>of</strong> gas-conta<strong>in</strong><strong>in</strong>g organs due to<br />

changes <strong>in</strong> ambient pressure<br />

65


Pulmonary Barotrauma<br />

67


Pulmonary Barotrauma<br />

68


Cerebral Arterial Gas Embolism (CAGE)<br />

69


CAGE<br />

• Symptoms usually start dur<strong>in</strong>g or<br />

immediately after surfac<strong>in</strong>g (85% < 5<br />

m<strong>in</strong>utes <strong>of</strong> surfac<strong>in</strong>g)<br />

• Symptoms<br />

– LOC<br />

– Paralysis or weakness<br />

– Numbness<br />

– Dizz<strong>in</strong>ess<br />

– Blurred vision<br />

– Personality change<br />

– Disorientation<br />

– +/- symptoms <strong>of</strong> Pneumothorax,<br />

Pneumomediast<strong>in</strong>um, Subcutaneous<br />

Emphysema<br />

70


Decompression Sickness (DCS)<br />

72


Decompression Sickness (DCS)<br />

• “Formation <strong>of</strong> bubbles <strong>in</strong> blood or body tissues on return<strong>in</strong>g<br />

to a lower pressure environment, due to <strong>in</strong>adequate<br />

elim<strong>in</strong>ation <strong>in</strong>ert gas dissolved <strong>in</strong> body tissues”<br />

73


DCS - Pathophysiology<br />

• Direct bubble effects<br />

– blockage - tissue hypoxia, venous<br />

congestion, direct pressure,<br />

• Indirect bubble effects<br />

– leaky capillaries, sludg<strong>in</strong>g, , activation <strong>of</strong><br />

platelets, coagulation, fat emboli from<br />

damaged tissues, histam<strong>in</strong>e release.<br />

74


DCS – Symptoms <strong>and</strong> Signs<br />

• 90% with<strong>in</strong> 15 m<strong>in</strong>utes to 12 hours after surfac<strong>in</strong>g<br />

• Symptoms <strong>and</strong> Signs<br />

– Pa<strong>in</strong>, <strong>in</strong> the jo<strong>in</strong>ts <strong>of</strong> arms, legs or trunk<br />

– Paralysis or Weakness<br />

– Numbness or paraesthesia<br />

– Tiredness, Nausea, Headache, Dizz<strong>in</strong>ess, Unusual Fatigue<br />

– Rash & Itch<strong>in</strong>g<br />

– Chest tightness or shortness <strong>of</strong> breath<br />

– LOC, altered level <strong>of</strong> consciousness.<br />

– Loss <strong>of</strong> balance<br />

– Change <strong>in</strong> Personality<br />

– Visual disturbance, Speech disturbance<br />

– Convulsions<br />

– Hear<strong>in</strong>g Loss / T<strong>in</strong>nitus<br />

– SOB, Haemoptysis<br />

75


DCS – Types / Classification<br />

Traditional:<br />

– Type I - Sk<strong>in</strong>, Lymph-node, Muscle, Jo<strong>in</strong>t<br />

– Type II – Neurological, CardioRespiratory, , Inner Ear<br />

76


DCS versus CAGE<br />

• Diagnostic confusion<br />

• Same treatment modality<br />

• Decompression Illness = DCS + CAGE<br />

– Descriptive classification (e.g. Acute Neurological<br />

Decompression Illness)<br />

79


Oxygen Recompression <strong>The</strong>rapy<br />

• Mechanism:<br />

– Decrease bubble size (Boyle’s s Law)<br />

– Hasten nitrogen elim<strong>in</strong>ation (Henry’s s Law)<br />

– Increase oxygenation to hypoxic areas<br />

– Reduces secondary bubble effects<br />

80


Demography<br />

(N=159)<br />

DCI cases treated at Dept <strong>of</strong> <strong>Div<strong>in</strong>g</strong> <strong>Medic<strong>in</strong>e</strong>, AFH Lumut<br />

between 1st October 1996 <strong>and</strong> 31st December 2003<br />

82


Incidence<br />

50<br />

45<br />

40<br />

35<br />

30<br />

Cases<br />

25<br />

20<br />

15<br />

1<br />

5<br />

1<br />

45<br />

2<br />

10<br />

5<br />

17<br />

20<br />

1<br />

7<br />

21<br />

16<br />

1<br />

11<br />

4<br />

7<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003<br />

Year<br />

Arterial Gas Embolism<br />

Decompression illness<br />

83<br />

(Sumber: Statistik Jabatan Perubatan Selam 1996-2004)


Incidence<br />

Commercial -<br />

Others<br />

13%<br />

21 8<br />

Military<br />

5%<br />

75 55<br />

Commercial - UW<br />

Loggers<br />

47%<br />

Recreational<br />

35%<br />

84


Underwater Logg<strong>in</strong>g<br />

86


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

0 - 33<br />

87


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

Dive:<br />

Depth (m) 28.3 (17.5)<br />

No <strong>of</strong> dives<br />

Dive Pr<strong>of</strong>ile<br />

2 (median)<br />

Non-Provocative: 56 (35)%<br />

Provocative: 103 (65%)<br />

0 - 33<br />

5 – 75<br />

1 - 10<br />

88


Demography <strong>and</strong> Dive Characteristics<br />

Mean<br />

(SD)<br />

Range<br />

Age (years) 31.5 (8.4) 15 - 57<br />

Gender Male: 141 Female: 18<br />

Dive Experience (years) 3.2 (5.3)<br />

Dive:<br />

Depth (m) 28.3 (17.5)<br />

No <strong>of</strong> dives<br />

Dive Pr<strong>of</strong>ile<br />

Delay to Initial Emergency<br />

Treatment (hours)<br />

2 (median)<br />

Non-Provocative: 56 (35)%<br />

Provocative: 103 (65%)<br />

3.3 (2.7)<br />

Delay to Recompression (hours) 12.3 (9.7)<br />

0 - 33<br />

5 – 75<br />

1 - 10<br />

1 - 12<br />

5 – 48<br />

89


Convulsions<br />

Rash/Itch<br />

90<br />

Shortness <strong>of</strong> breath<br />

Headache<br />

Fatigue<br />

Ur<strong>in</strong>ary retention<br />

Visual symptoms<br />

Loss <strong>of</strong> consciousness<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Symptoms <strong>and</strong> Signs<br />

N = 158<br />

Numbness/Paraesthesia<br />

Pa<strong>in</strong><br />

Weakness/Paralysis<br />

Dizz<strong>in</strong>ess/Vertigo/Nausea/Vomit<strong>in</strong>g<br />

Number <strong>of</strong> Cases


Sp<strong>in</strong>al/Cerebral<br />

Symptoms <strong>and</strong> Signs<br />

Cerebral<br />

32%<br />

Miss<strong>in</strong>g<br />

Neurological (66%)<br />

N = 158<br />

9%<br />

Periph<br />

1%<br />

Sp<strong>in</strong>al<br />

57%<br />

94<br />

51<br />

3<br />

Musculoskeletal (32%)<br />

CVS / RS (2%)<br />

Miss<strong>in</strong>g<br />

4.8%<br />

Others<br />

9.5%<br />

Site <strong>of</strong> Pa<strong>in</strong><br />

Upper Limb<br />

23.8%<br />

Sp<strong>in</strong>e/Trunk<br />

33.3%<br />

Lower Limb<br />

91<br />

28.6%


Treatment Outcomes<br />

Mild Residual<br />

Symptoms<br />

17%<br />

Severe<br />

Residual<br />

Symptoms<br />

15%<br />

27<br />

23<br />

108<br />

Full Recovery<br />

68%<br />

92


Other Complications<br />

• Cranial diabetes <strong>in</strong>sipidus (3 cases)<br />

• Lobar pneumonia (2 cases)<br />

• Pulmonary oxygen toxicity - nil<br />

93


Prevention<br />

97


Tra<strong>in</strong><strong>in</strong>g<br />

98


Tra<strong>in</strong><strong>in</strong>g<br />

99


<strong>Div<strong>in</strong>g</strong> Medical Exam<strong>in</strong>ations<br />

800<br />

700<br />

668<br />

Jumlah Pemeriksaan<br />

Activities<br />

600<br />

500<br />

400<br />

300<br />

200<br />

328<br />

452<br />

534<br />

408<br />

547<br />

502<br />

545<br />

100<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003<br />

Tahun<br />

Source: DDHM Annual Returns Nov 1996 - Dec 2002<br />

100


<strong>Div<strong>in</strong>g</strong> Medical Exam<strong>in</strong>ations<br />

800<br />

700<br />

668<br />

Jumlah Pemeriksaan<br />

Activities<br />

600<br />

500<br />

400<br />

300<br />

200<br />

328<br />

452<br />

534<br />

408<br />

547<br />

502<br />

545<br />

100<br />

0<br />

1996 1997 1998 1999 2000 2001 2002 2003<br />

Tahun<br />

Source: DDHM Annual Returns Nov 1996 - Dec 2002<br />

101


Field Medical Support for <strong>Div<strong>in</strong>g</strong> Ops<br />

102


<strong>Malaysia</strong>n <strong>Div<strong>in</strong>g</strong> Emergency Hotl<strong>in</strong>e<br />

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