Advanced Wound Modalities Options for Complex, Chronic Wounds

Wound Healing:
Proliferation
• Proliferation of cells, granulation of wound
bed and constriction of wound
• Pebbled red tissue forms in wound bed
– Fibroblasts- start framework of new
dermis
– Pericytes- regenerate capillaries
– Endothelial cells- product lining of
vessels
– Keratinocytes- epithelialization of
wound
• Wound contracts
• “Building crews putting frame of house
together”