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Preventive role of Cactus (Opuntia ficus-indica) cladodes on the ...

Preventive role of Cactus (Opuntia ficus-indica) cladodes on the ...

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I- Protective effect <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>Cactus</str<strong>on</strong>g> cladode<br />

against <strong>the</strong> oxidative stress induced by<br />

Zéaralén<strong>on</strong>e<br />

• Balb/c mice: 25 g<br />

• 6 groups : 5 mices<br />

• Administrati<strong>on</strong> intra-péritoral <str<strong>on</strong>g>of</str<strong>on</strong>g>:<br />

Experimental c<strong>on</strong>diti<strong>on</strong>s<br />

• Gpe 1:100 µl Éthanol/H2O: c<strong>on</strong>trol 1<br />

• Gpe 2: 100 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> cladode extract : c<strong>on</strong>trol 2<br />

• Gpe 3: 40 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> Zearalen<strong>on</strong>e ( ZEN)<br />

• Gpe 4: 40 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> ZEN + 25 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> cladode extract<br />

• Gpe 5: 40 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> ZEN + 50 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> cladode extract<br />

• Gpe 6: 40 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> ZEN + 100 mg/Kg <str<strong>on</strong>g>of</str<strong>on</strong>g> cladode extract<br />

• Sacrificed after 24 heures :liver, Kidney, blood, b<strong>on</strong>e marow…

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