Selective Laser Trabeculoplasty as Primary Therapy in Patients with ...
Selective Laser Trabeculoplasty as Primary Therapy in Patients with ...
Selective Laser Trabeculoplasty as Primary Therapy in Patients with ...
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Introduc%on <br />
Ø Selec%ve <strong>L<strong>as</strong>er</strong> <strong>Trabeculopl<strong>as</strong>ty</strong> (SLT) uses a Q-‐Switched frequency-‐doubled <br />
(532 nm), low energy Nd:YAG l<strong>as</strong>er, which targets melanocytes <strong>in</strong> the <br />
trabecular meshwork 1,2 . <br />
Ø SLT treatment <strong>in</strong>duces a biologic response <strong>in</strong> the trabecular meshwork, <br />
which <strong>in</strong>volves the rele<strong>as</strong>e of cytok<strong>in</strong>es that trigger macrophage recruitment <br />
and other changes, lead<strong>in</strong>g to reduc%on <strong>in</strong> <strong>in</strong>traocular pressure (IOP). <br />
Ø SLT treats the trabecular meshwork <strong>with</strong>out caus<strong>in</strong>g thermal nor coagula%ve <br />
damage to surround<strong>in</strong>g structures. <br />
1. La%na MA, et al. Selec%ve targe%ng of trabecular meshwork cells: <strong>in</strong> vitro studies of pulsed and CW l<strong>as</strong>er <strong>in</strong>terac%ons. <br />
. <br />
Exp Eye Res. 1995;60:359-‐372. <br />
2. La%na MA, et al. Q-‐switched 532-‐nm Nd:YAG l<strong>as</strong>er trabeculopl<strong>as</strong>ty (selec%ve l<strong>as</strong>er trabeculopl<strong>as</strong>ty): a mul%center, pilot, <br />
cl<strong>in</strong>ical study. Ophthalmology. 1998;105:2082-‐2090.
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