Abstract Book - Ira A. Fulton Schools of Engineering - Arizona State ...

Lytic Peptides as Cancer Therapeutics
Jennifer Gamboa, Chemical Engineering
Graduation: May 2011 Hometown: Centennial, Colorado
Mentor: Dr. Kaushal Rege, Chemical Engineering
Grand Challenge: Engineer better medicines
KLA, a lytic peptide, can sensitize prostate cancer cells to apoptosis induced by death receptor agonistic
antibodies. This research involves an investigation into gold nanorod-mediated delivery of the KLA peptide, since
peptides by themselves are easily degraded and rapidly cleared in vivo. Gold nanorods, with light absorption
properties, were conjugated with methoxy (polyethylene glycol)-thiol for stabilization and then KLA was attached
and tested with PC3 TR prostate cancer cells. Results have shown the stability and effectiveness of gold nanorod-
KLA complexes in inducing cancer cell death, indicating the potential of the nanoparticle-mediated approach for
combined imaging and delivery of peptides.
Fully-Autonomous Modular Flight Control System
Mark Garrison, Electrical Engineering
Graduation: May 2011 Hometown: Glendale, Arizona
Mentor: Dr. Michael Goryll, Electrical Engineering
Grand Challenge: Prevent nuclear terror
The goal of this project is to produce an autonomous flight control system for small, inexpensive remote control
helicopters. To this end, a circuit board has been designed and built to fly a 13” helicopter. This board employs
an accelerometer and flash to record data from flight which will be used to develop the control algorithm. So far,
minor flaws in the board assembly are preventing the device from recording data. Currently, these problems are
being fixed and firmware is being developed to record the flight data. Once installed on the helicopter, different
control algorithms will be tested during flight.
Development of a Rocket Deployed UAV
Bradley Goodman, Aerospace Engineering
Graduation: May 2010 Hometown: Great Falls, Montana
Mentor: Dr. Marion Vance and Mr. James Villarreal, Mechanical and Aerospace
Engineering
Grand Challenge: Engineer the tools of scientific discovery
Current Unmanned Aerial Vehicles (UAVs) being used by the military have one major drawback, they are relatively
slow to deploy. To address this issue, research is being carried out into the development of a rocket launched
UAV known as the Rapid Ascent Reconnaissance Vehicle (RAR-V). With the design of the airframe completed
and construction underway, the majority of research done this semester has gone towards high fidelity flight
simulation and performance estimation.
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Arizona State University u FURI Research Symposium