Parsol 1789 - GreenCupboards
Parsol 1789 - GreenCupboards
Parsol 1789 - GreenCupboards
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PARSOL ® <strong>1789</strong><br />
DSM Nutritional Products
Description<br />
PARSOL ® <strong>1789</strong> is an oil-soluble UV-A filter.<br />
Chemical structure<br />
Comparative UV absorption spectra of<br />
PARSOL ® <strong>1789</strong> vs. Benzophenone-3<br />
(1 0 mg/ L in absolute ethanol)<br />
Absorbance<br />
1.5 Benzophenone-3<br />
PARSOL ® <strong>1789</strong><br />
1<br />
0.5<br />
C 20<br />
H 22<br />
O 3<br />
M r<br />
310.4<br />
CAS No.: 70356-09-1<br />
EINECS No.: 274-581-6<br />
INCI name: butyl methoxydibenzolymethane<br />
Chemical name: 1-(4-tert-butylphenyl)-3- (4-<br />
methoxyphenyl)-propane-1, 3-dione<br />
USAN nomenclature: avobenzone<br />
Physical and chemical properties<br />
Appearance:<br />
Odour:<br />
Melting point: 81.0–86.0 °C<br />
Assay (HPLC): min. 95.0%<br />
UV specific extinction<br />
(E 1%, 1 cm at 357 ±2 nm<br />
white to pale yellow powder<br />
slightly aromatic<br />
in absolute ethanol): 1100–1180<br />
Flash point (liquid): > 100 °C (212 °F)<br />
UV absorption spectra<br />
PARSOL ® <strong>1789</strong><br />
Absorbance Absorbtion (%)<br />
2.5<br />
2<br />
1.5<br />
1<br />
0.5<br />
5 mg/ L<br />
10 mg/L<br />
20 mg/ L<br />
0<br />
250 300 350 400<br />
Wavelength (nm)<br />
Blend of PARSOL ® <strong>1789</strong> and PARSOL ® MCX<br />
50/5 0 w/ w<br />
99.7<br />
99.0<br />
96.8<br />
90.0<br />
68.4<br />
Absorbance Absorbtion (%)<br />
2.5<br />
2<br />
10 mg/L<br />
20 mg/ L<br />
40 mg/L<br />
0<br />
99.7<br />
99.0<br />
Stability and storage<br />
PARSOL ® <strong>1789</strong> is incompatible with formaldehyde,<br />
formaldehyde donor preservatives and heavy<br />
metals (pink-orange colour with iron). A sequestering<br />
agent is recommended. Formulations with<br />
PABA and its esters develop a yellow colour.<br />
Can form complexes with aluminium above pH 7,<br />
with free aluminium resulting from the coating of<br />
some grades of microfine pigments.<br />
The product may be stored for 24 months from the<br />
date of manufacture in the unopened original<br />
container and at a temperature below 25 °C. The<br />
‘best used before’ date is printed on the label.<br />
Store in tight containers protected from light.<br />
Suitable materials for containers are stainless<br />
steel, dark glass, polyethylene and enamel.<br />
Uses<br />
0<br />
250 300 350 400<br />
Wavelength (nm)<br />
Instrument: Uvikon 941<br />
Cell thickness: 1 cm<br />
Solvent: absolute ethanol<br />
PARSOL ® <strong>1789</strong>, combined with recognized safe<br />
and effective UV-B filters, provides broad-spectrum<br />
protection in skin and sun-care preparations.<br />
PARSOL ® <strong>1789</strong> can be used for the formulation of<br />
protective hair-care, medicated skin-care and<br />
protective skin-tone preparations.<br />
It can be used to quench phototoxic skin reactions<br />
initiated by weak phototoxic materials.<br />
1.5<br />
1<br />
0.5<br />
0<br />
250 300 350 400<br />
Wavelength (nm)<br />
96.8<br />
90.0<br />
68.4<br />
0
Solubility<br />
Solvent<br />
Solubility<br />
(% w/w, 20 °C)<br />
Best results are obtained when part of the Na2<br />
EDTA is added to the oil phase. Preservative<br />
agents must be selected carefully (see table<br />
below). Avoid formaldehyde donors.<br />
PARSOL MCX (octyl methoxycinnamate) 25<br />
Crodamol DA (diisopropyl adipate) 19<br />
Miglyol 812 (caprylic/capric triglyceride) 14<br />
Finsolv TN (C12-C15 alkyl benzoate) 14<br />
Cetiol HE (peg-7 glyceryl cocoate) 12<br />
Cetiol A (hexyl laurate) 11<br />
Finsolv SB (isostearyl benzoate) 11<br />
Deltyl Extra (isopropyl myristate) 10<br />
Estol 1517 IPP (isopropyl palmitate) 10<br />
Finsolv BOD (octyldodecyl benzoate) 10<br />
Dermol 105 (isodecyl neopentanoate) 9<br />
Cetiol LC (coco-caprylate/ caprate) 9<br />
Hetester FAO (C12-C15 alkyl octanoate 9<br />
Finsolv P (PPG-15 stearyl ether benzoate) 9<br />
Arlamol E (PPG-stearyl benzoate) 8<br />
Cetiol 868 (octyl stearate) 8<br />
Cetiol V (decyl oleate) 8<br />
Crodamol cap (cetearyl octanoate) 7<br />
Elefac I-205 (octyldodecyl neopentanoate) 6<br />
Isopropyl alcohol (99%) (isopropanol) 2<br />
Ethyl alcohol 96% vol.(ethanol) 2<br />
Light mineral oil (mineral oil) 1<br />
Propylene glycol (propylene glycol) 0.2<br />
Silicone 344 fluid (cyclomethicone) 0.2<br />
Glycerin 0.1<br />
Water<br />
Insoluble<br />
Recommended use levels<br />
Formulate according to local regulations. See also<br />
Regulatory status.<br />
In sunscreen products: 2–3%<br />
In everyday skin-care products: 1–2%.<br />
Formulating techniques and handling<br />
tips<br />
PARSOL ® <strong>1789</strong> is oil-soluble and should be<br />
incorporated into the heated oil phase.<br />
Consult the table Solubility to ensure that<br />
PARSOL ® <strong>1789</strong> is properly dissolved, in order to<br />
avoid the formation of crystals.<br />
To avoid the formation of complexes of PARSOL ®<br />
<strong>1789</strong> with metals, it is recommended to add<br />
0.05–0.1% of disodium EDTA.<br />
Stabilizing additives<br />
• Chelating materials to prevent coloration with<br />
metallic ions<br />
• Antioxidants<br />
Recommended preservative agents<br />
Commercial name INCI name<br />
Phenonip Phenoxyethanol &<br />
methylparaben &<br />
ethylparaben &<br />
propylparaben<br />
& butylparaben<br />
Nipagin<br />
M Methylparaben<br />
Phenoxetol Phenoxyethanol<br />
Kathon CG Methylchloroisothiazolinone<br />
& methylisothiazolinone<br />
Irgasan DP 300 Triclosan<br />
Glycacil-L Iodopropynyl<br />
butylcarbamate<br />
Nipaguard DCB Methyldibromo glutaronitrile<br />
Benzoic acid Benzoic acid<br />
Materials to be avoided<br />
• Iron and ferric salts<br />
• Heavy metals<br />
Regulatory status<br />
• Formaldehyde donors<br />
• PABA and PABA<br />
esters<br />
TSCA/EEC: registered<br />
USA: approved, at levels of maximum 3%<br />
alone (at least SPF 2) and 2–3% in<br />
combination with other<br />
UV sunscreens. See Federal<br />
Register Vol.62, No.83, April 30,<br />
1997 /Rules and Regulations,<br />
outlining conditions under which<br />
PARSOL ® <strong>1789</strong> can be marketed in<br />
the USA.<br />
EU: listed in Council Directive<br />
76/768/EEC, Annex VII,<br />
Part I: max. 5%.<br />
Japan: JSCI/JCID listed.
The Science In Beauty<br />
Many of the leading cosmetics and personal care companies have realized the synergy<br />
between vitamins, sunscreens, omega-6 oils and phospholipid emulsifiers, and are<br />
incorporating them into their products at the proper levels, utilizing innovative delivery<br />
systems and technologies to develop functional, high performance cosmetics.<br />
In addition to having invented the synthesis of many of these ingredients, at DSM Nutritional<br />
Products we have explored the science behind the activity of these ingredients and<br />
developed concepts, addressing specific global and especially Asian trends in hair care,<br />
skin care and oral care.<br />
Unlimited. Cosmetics<br />
Area North America<br />
DSM Nutritional Products Inc.<br />
45 Waterview Boulevard<br />
Parsippany, NJ 07054-1298<br />
USA<br />
Tel. + 1 800 526 0189<br />
Fax + 1 973 257 8420<br />
www.nutraaccess.com<br />
Area Asia Pacific<br />
DSM Nutritional Products Asia Pacific Pte. Ltd.<br />
Shenton Way # 21-00<br />
MCL Building<br />
Singapore 079 120<br />
Tel. + 65 6325 6200<br />
Fax + 65 6220 1976<br />
www.dsmnutritionalproducts.com<br />
Area China<br />
DSM China<br />
Ocean Tower 22/F<br />
No. 550 Yan An East Road<br />
Shanghai 200001<br />
P. R. China<br />
Tel. + 86 21 3310 4988<br />
Fax + 86 21 6352 5511<br />
www.roche.com.cn/vitamin.htm<br />
Area Latin America<br />
DSM Nutritional Products Latin America<br />
Av. Eng. Billings, 1729 – Prédio 9<br />
05321-900 São Paulo – SP<br />
Brasil<br />
Tel. + 55 11 3719 4601<br />
Fax + 55 11 3719 4684<br />
www.dsmnutritionalproducts.com<br />
Area Europe, Middle East and Africa<br />
DSM Nutritional Products Europe Ltd<br />
P.O. Box 3255<br />
CH-4002 Basel<br />
Switzerland<br />
Tel. + 41 61 687 17 77<br />
Fax + 41 61 687 20 82<br />
www.dsmnutritionalproducts.com<br />
The information given in this leaflet is based on our current knowledge<br />
and experience, and may be used at your discretion and risk. It does<br />
not relieve you from carrying out your own precautions and tests.<br />
We do not assume liability in connection with your product or its use.<br />
You must comply with all applicable laws and regulations, and<br />
observe all third-party rights.<br />
DSM Nutritional Products Europe Ltd<br />
P.O. Box 3255<br />
CH-4002 Basel<br />
Switzerland<br />
www.dsmnutritionalproducts.com<br />
05/2005 · designed by: GAS.Grenzach@t-online.de · Printed in Germany