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Pure, liquid fish oil, used in clinical study involving
Rett syndrome patients published March, 2012.
One step ahead for your health
In this brochure you can read some
details about the study.
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Omega-3 fish oil in your daily diet
It has long since been established that Omega-3 is good
for everyone. It is necessary for optimal function of many of
our organs, and our own body just doesn’t produce it. While
some Omega-3 can be obtained through a balanced diet,
it is in most cases useful to take a dietary supplement that
provides sufficient polyunsaturated fatty acids or Omega-3.
Your skin, your joints, your eye-sight, your brain and your
immune system will work at their best when given Omega-3,
and your heart will simply love you for it. Omega-3 is great for
your health. This is a health fact which has been documented
in clinical studies around the world again and again.
Rett syndrome and fatty acids
In a recent pilot study published in March 2012 on the International peerreviewed
journal “Genes and Nutrition”, a group of scientists and clinicians
headed by the Italian dr Claudio de
Felice, points out some important
positive effects achieved in patients
with Rett syndrome in the earliest
stage of this genetic disease by using
Norwegian Fish Oil Liquid Omega-3 at
high dosage.
www.mamut.net/TransformaEurope
Liquid Omega-3

Partial rescue of Rett syndrome by ω-3 polyunsaturated
fatty acids (PUFAs) oil
Claudio De Felice, Cinzia Signorini, Thierry Durand, Lucia Ciccoli, Silvia
Leoncini, Maurizio D’Esposito, Stefania Filosa, Camille Oger, Alexandre Guy
and Valérie Bultel-Poncé, et al.
Published in Genes & Nutrition.
March, 2012.
www.springerlink.com
...”A significant reduction in the clinical severity (in particular,
motor-related signs, nonverbal communication deficits,
and breathing abnormalities) together with a significant
decrease in all the examined oxidative stress markers was observed in
the ω-3 PUFAs supplemented patients, whereas no significant
changes were evidenced in the untreated group.”
.... “For the first time, these findings strongly suggest that a dietary
intervention in this genetic disease at an early stage of its natural
history can lead to a partial clinical and biochemical
rescue.”
Clinical severity score (CSS) changes following 6month
ω-3 PUFAs supplementation in stage I RTT
patients (individual items)
Clinical manifestation Severity score P value
Before ω-3
PUFAs
supplementation
After ω-3
PUFAs
supplementation
(6 months)
Age of onset of regression 4 [4-4] 4 [4-4] 1.0
Somatic growth 1.5 [1-2] 1 [1-2] 0.8182
Head growth 3 [3-3] 3 [3-3] 1.0
Motor/independent sitting 4 [4-4] 0 [0-1] 0.0087
Ambulation 5 [5-5] 1 [1-4] 0.0152
Hand use 4 [4-4] 2 [2-2] 0.0022
Scoliosis 0 [0-0] 0 [0-0] 1.0
Language 4 [4-4] 3 [3-4] 0.0649
Nonverbal communication 5 [5-5] 0 [0-1] 0.0022
Respiratory dysfunction 4 [4-4] 1 [0-1]