Liposuction
Liposuction
Liposuction
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<strong>Liposuction</strong>: A Gynecologist’s Perspective<br />
evaluation of very subjective surgical results<br />
(Figures 1-3, page 00).<br />
Anesthesia<br />
Tumescent anesthesia revolutionized<br />
liposuction as compared to the earlier<br />
techniques performed under general<br />
anesthesia. The local approach to anesthesia<br />
has brought liposuction out of<br />
the operating room and into the office<br />
in carefully selected cases. To achieve<br />
FOCUSPOINT‣<br />
Safety with tumescent anesthesia<br />
is well established but requires<br />
careful attention to dose.<br />
tumescent anesthesia, a dilute solution<br />
of lidocaine, epinephrine, and sodium<br />
bicarbonate is introduced by needle or<br />
cannula into the tissue to be treated.<br />
This infiltration anesthetizes the tissue,<br />
constricts blood vessels for improved<br />
hemostasis, expands the adipose treatment<br />
area for improved safety, and provides<br />
postoperative analgesia.<br />
In vitro evidence demonstrates that<br />
lidocaine is actually bactericidal for<br />
organisms isolated from skin lesions. 5-7<br />
Lidocaine appears to have antibacterial<br />
effects for both gram-negative and grampositive<br />
bacteria, and in gram-negative<br />
bacteria, such as Escherichia coli and<br />
Pseudomonas aeruginosa, lidocaine appears<br />
to act synergistically with antibiotics<br />
by depolarizing the bacterial cell<br />
membrane and increasing cell membrane<br />
permeability. 6 Though in vivo<br />
studies have been mixed, supportive<br />
findings in vitro may explain the very<br />
low rate of infection associated with<br />
procedures utilizing this technique.<br />
Safety with tumescent anesthesia is<br />
well established but requires careful<br />
attention to dose. The lipophilic properties<br />
of lidocaine and the vasoconstriction<br />
of epinephrine facilitate the<br />
recovery of much of the administered<br />
dose with the aspirated adipose tissue.<br />
An infiltration of up to 45 to 50 mg/kg of<br />
lidocaine is generally considered a safe<br />
threshold for dosing tumescent anesthesia.<br />
The mixture used is typically 1000<br />
mg of lidocaine (2 x 50-cc bottles), 1 mg<br />
of epinephrine (1 ampule of 1:1000), and<br />
10 mEq sodium bicarbonate per liter. 8,9<br />
Lidocaine toxicity is rare, but includes<br />
cardiac arrhythmias and central nervous<br />
system effects including seizures.<br />
Surgical complications associated with<br />
liposuction include hematoma, seroma,<br />
infection, embolic events, tissue necrosis,<br />
and contour irregularities. Any office<br />
or facility providing liposuction<br />
must be fully prepared for such complications.<br />
Despite the potential risk, a<br />
2002 review of 66,000 cases using tumescent<br />
anesthesia identified a complication<br />
rate of 0.68 per thousand and<br />
no deaths. 10 Another review including<br />
15,336 patients undergoing tumescent<br />
liposuction did not identify any serious<br />
complications. 11<br />
The Procedure<br />
Preparation for a liposuction procedure<br />
begins with the patient selection process<br />
and thorough counseling about<br />
risks and expectations. Laboratory testing<br />
varies but often includes a complete<br />
blood count, prothrombin time, partial<br />
thromboplastin time, hepatitis panel,<br />
and HIV screening. Vitamin K is sometimes<br />
administered preoperatively to<br />
limit ecchymosis.<br />
Perioperative antibiotic prophylaxis<br />
is typical and may be continued for several<br />
days postoperatively. In addition<br />
to tumescent anesthesia, the surgeon’s<br />
choice of narcotic and anxiolytic may<br />
be administered. We use oral dosing and<br />
do not establish intravenous access.<br />
Patients are marked prior to infiltration<br />
of tumescent fluid to highlight focal<br />
areas of adipose tissue to guide aspiration<br />
efforts. Skin preparation and<br />
draping are performed as per standard<br />
surgical aseptic technique. Small 1- to<br />
42 The Female Patient | VOL 37 MARCH 2012