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1/30/2013<br />

<strong><strong>Cell</strong>s</strong>: <strong>The</strong> <strong>Living</strong> <strong>Units</strong><br />

<strong>Cell</strong> <strong>The</strong>ory<br />

• 1) <strong><strong>Cell</strong>s</strong> = basic functional & structural units of<br />

the body<br />

• 2) All cells come from pre-existing cells<br />

• 3) All cells have the same DNA<br />

• 4) Maintain homeostasis<br />

<strong>Cell</strong><br />

Division<br />

<strong>Cytology</strong><br />

US Debt =<br />

16 trillions <strong>Cell</strong>ular <strong>Diversity</strong><br />

• 1) <strong><strong>Cell</strong>s</strong> = basic structural and functional units<br />

of all living things<br />

– A) 30-75 trillion cells<br />

– B) <strong>Cell</strong>ular diversity = 200 different types<br />

• diverse in size, shape, and function<br />

Figure 2.18b<br />

<strong>Cell</strong>ular <strong>Diversity</strong><br />

3 principal parts of a cell<br />

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1/30/2013<br />

Plasma Membrane<br />

• 1) defines the extent of the cell<br />

• 2) Structure<br />

– A) lipid bilayer<br />

– B) membrane proteins<br />

• Integral proteins<br />

• Peripheral proteins<br />

Plasma Membrane<br />

• 1) Functions<br />

– A) act as receptors<br />

– B) Separates two major fluid compartments<br />

– C) Semi-permeable<br />

• Selective transport across membrane<br />

• 2) Membrane Transport Mechanisms<br />

– A) Passive transport: simple vs. facilitated diffusion<br />

– B) Active transport<br />

• Small molecules: primary vs. secondary active transport<br />

• Macromolecules: vesicular transport (endocytosis vs.<br />

exocytosis)<br />

Osmosis<br />

Vesicular Transport<br />

Cytoplasm<br />

A<br />

• major elements<br />

– 1) Cytosol<br />

• Consists of water, ions, and enzymes<br />

– 2) Organelles<br />

– 3) inclusions<br />

• Melanin<br />

• Lipid droplets<br />

B<br />

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1/30/2013<br />

organelles<br />

Hereditary Information<br />

• 1) Mitochondria<br />

• 2) Endoplasmic<br />

reticulum<br />

– Protein synthesis<br />

– lipid metabolism<br />

– detoxify poisons & drugs<br />

• 3) Golgi apparatus<br />

• 4) Lysosomes<br />

• 5) peroxisomes<br />

– neutralize free radicals<br />

• 6) Ribosomes<br />

• 7) Centrosomes =<br />

Microtubule-organizing<br />

center<br />

– Centrioles - cylindrical<br />

bodies<br />

• 8) Cytoskeleton<br />

– Maintains cell shape<br />

– <strong>Cell</strong> transport<br />

• 1) Genome = hereditary<br />

information<br />

– 30,000 genes<br />

• 2) 46 chromosomes<br />

• 3) DNA<br />

– Chromatin<br />

– Chromosome<br />

Central Dogma of Biology<br />

• DNA => RNA => Protein<br />

– Transcription<br />

– Translation<br />

• Modification &<br />

Processing<br />

• Export<br />

<strong>Cell</strong> Division<br />

• 1) Meiosis – sex cells<br />

• 2) Mitosis – somatic cells<br />

– A) Interphase: Preparation<br />

– B) Mitotic phase: cell<br />

division<br />

• 1) Mitosis: duplication<br />

of DNA and division of<br />

the nucleus<br />

– Chromosomes<br />

distributed to 2 daughter<br />

nuclei<br />

• 2) Cytokinesis: division<br />

of the cytoplasm<br />

Mitotic phase<br />

3

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