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LUCIE YANG, MD-PhD - ANSIR Laboratory

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CURRICULUM VITÆ<br />

<strong>LUCIE</strong> <strong>YANG</strong>, <strong>MD</strong>-<strong>PhD</strong><br />

Postdoctoral Fellow<br />

Department of Radiology<br />

<strong>ANSIR</strong> lab, PP1, 7 th floor<br />

Wake Forest University School of Medicine<br />

Medical Center Blvd., Winston-Salem, NC 27157 USA<br />

Phone: (336) 716-0473 Fax: (336) 716-0798<br />

Email: yanglucie@yahoo.com<br />

Education<br />

Present Post-Doctoral Fellowship<br />

Dept of Radiology, Wake Forest University School of Medicine<br />

Mentors: Paul Laurienti, <strong>MD</strong>-<strong>PhD</strong> and Joseph Maldjian, <strong>MD</strong><br />

2006 Radiology Residency<br />

Dept of Radiology, Wake Forest University School of Medicine<br />

Program Director: Rita Freimanis, <strong>MD</strong><br />

2005 General Surgery Internship<br />

Dept of Surgery, University of California, San Francisco<br />

Program Director: Linda Reilly, <strong>MD</strong><br />

2004 Doctor of Medicine<br />

University of California, San Francisco<br />

2002 Doctor of Philosophy<br />

Biochemistry and Molecular Biology, University of California, San Francisco<br />

Mentor: Cynthia Kenyon, <strong>PhD</strong><br />

1994 Bachelor of Science<br />

Chemistry, Summa Cum Laude, University of Maryland, College Park<br />

Mentor: Daniel Falvey, <strong>PhD</strong><br />

Professional Experiences / Other Research Experiences<br />

2007-present Small Group Facilitator (Scientific Integrity and Professionalism)<br />

Graduate School, Wake Forest University School of Medicine<br />

2003-2005 Neuroradiology Research Fellow<br />

Mentors: Soonmee Cha, <strong>MD</strong> and William Dillon, <strong>MD</strong><br />

University of California, San Francisco<br />

2001-2002 Science Educator (Fourth Grade Students)<br />

Science and Health Education Partnership<br />

University of California, San Francisco / San Francisco Unified School District<br />

1998-1999 Teaching Assistant (Biochemistry)<br />

School of Medicine, University of California, San Francisco<br />

<strong>YANG</strong>, Page 1 of 6


1992-1994 Undergraduate Research Scholar<br />

Mentor: Daniel Falvey, <strong>PhD</strong><br />

Department of Chemistry, University of Maryland, College Park<br />

Summer 1993 Research Fellow<br />

Mentor: Bernardo Nadal-Ginard, <strong>MD</strong><br />

Department of Cardiology, Harvard Medical School<br />

Summer 1992 Cold Spring Harbor Undergraduate Research Program Scholar<br />

Mentor: David Helfman, <strong>PhD</strong><br />

Cold Spring Harbor <strong>Laboratory</strong><br />

Summer 1991 NIH Foundation for Advanced Education in the Sciences Research Scholar<br />

Mentor: David Davies, <strong>PhD</strong><br />

National Institute of Diabetic, Digestive, and Kidney Diseases, NIH<br />

Summer 1990 NIH Sobel-Howard Hughes Medical Institute Summer Research Scholar.<br />

Mentor: Dinah Singer, <strong>PhD</strong><br />

National Cancer Institute, NIH<br />

Honors and Awards<br />

2008 Voted “Best presentation” Statistical Parametric Mapping Course,<br />

(representative for Connectivity group, 10 total groups covering various topics),<br />

University College London, London<br />

2007 Accepted for participation in Multimodal Imaging Course (competitive<br />

application process, limited to 24 international attendees), Harvard-MIT-MGH<br />

Athinoula Martinos Center for Biomedical Imaging, Charlestown, MA<br />

2004 Trainee Travel Award International Society for Magnetic Resonance in<br />

Medicine Conference, Kyoto, Japan<br />

1994-2004 Medical Scientist Training Program Scholar (full stipend and tuition<br />

<strong>MD</strong>-<strong>PhD</strong> merit scholarship supported by the National Institutes of Health),<br />

Univ. of California, San Francisco<br />

1990-1994 Francis Scott Key Scholar (full tuition, books, room and board merit<br />

Scholarship), Univ. of Maryland, College Park<br />

1990-1994 Maryland Distinguished Scholarship.<br />

1990-1994 Omicron Delta Kappa and Mortar Board Honor Societies, Univ. of<br />

Maryland, College Park<br />

1994 Spirit of Maryland Award (presented to two senior class members for<br />

outstanding scholarship, leadership, campus involvement, and community<br />

service), Univ. of Maryland, College Park<br />

1993 Woman of Influence Leadership Award, Univ. of Maryland, College Park<br />

1993 College Chemistry Achievement Award, American Chemical Society.<br />

1993 American Institute of Chemists Award<br />

1992-1993 Barry Goldwater Scholarship (for independent study)<br />

1992 John Leidy Scholarship for Excellence in Chemistry Award.<br />

1991 Outstanding Freshman Chemical Rubber Company Chemistry Award<br />

1989 National Merit Commended Scholar<br />

1989 Summer Engineering Institute Scholarship, Northeastern Univ., Boston, MA<br />

1989 Bausch and Lomb Award in Science<br />

1989 American Computer Science League All-Star Contest High Scorer,<br />

Toronto, Ontario<br />

<strong>YANG</strong>, Page 2 of 6


Professional Licensure<br />

United States Medical License Examination<br />

Passed USMLE Parts I, II, and III<br />

North Carolina Medical License (#2007-00131)<br />

Passed American Board of Radiology Radiologic Physics Examination<br />

Professional Memberships<br />

American Medical Association (AMA)<br />

Cognitive Neuroscience Society (CNS)<br />

International Society for Magnetic Resonance in Medicine (ISMRM)<br />

Organization for Human Brain Mapping (OHBM)<br />

Radiological Society of North America (RSNA)<br />

Society for Neuroscience (SFN)<br />

Western North Carolina Society for Neuroscience (WNCSFN)<br />

Professional Services<br />

Committees:<br />

2008 Abstract Selection Committee for Human Brain Mapping Meeting<br />

Postdoctoral Representative<br />

Organization for Human Brain Mapping<br />

2006 Graduate Medical Education Internal Review Committee<br />

Resident Representative<br />

Wake Forest University Baptist Medical Center<br />

2005-2006 Conference Committee, Radiology Residency<br />

Wake Forest University Baptist Medical Center<br />

1995-1996 Brain and Behavior Subject Area Committee<br />

Student Representative<br />

School of Medicine, University of California, San Francisco<br />

1995-1996 7 th Annual AIDS Forum Organizing Committee (Chair)<br />

University of California, San Francisco<br />

1993-1994 Search Committee for Dean for Undergraduate Studies<br />

Student Representative<br />

University of Maryland, College Park<br />

1992-1994 Dean’s Committee on Undergraduate Education (to improve teaching)<br />

<strong>YANG</strong>, Page 3 of 6


Chair, 1993-1994<br />

University of Maryland, College Park<br />

1990-1994 Stamp Union Program Council, Issues and Answers Committee<br />

Chair, 1992-1993 (Outstanding committee of the year);<br />

Vice-chair, 1991-1992; Treasurer 1990-1991<br />

University of Maryland, College Park<br />

1991-1994 Student Honor Council (decided on cheating and plagiarism allegations)<br />

Presiding Officer, 1992-1994<br />

University of Maryland, College Park<br />

1991-1992 Honors Program Admissions (Co-chair) and Francis Scott Key<br />

Scholarship Selection Committees<br />

University of Maryland, College Park<br />

1990-1991 Student Parking Appeals Board<br />

University of Maryland, College Park<br />

1990-1991 President’s Colloquium Planning Committee<br />

University of Maryland, College Park<br />

Other Services:<br />

2008 Various service activities, including Habitat for Humanity<br />

2007 Various service activities, including Brain Awareness Week<br />

1994-2005 Various service activities, including Habitat for Humanity, San Francisco<br />

Homeless Clinic, Mission Neighborhood Health Fair<br />

1995-1996 Science Article Writer, University of California, San Francisco campus<br />

newspaper, Synapse<br />

1993 U.S. Senate Intern, Senator Barbara Mikulski, Maryland<br />

1990-1994 Various service activities including Washington, D.C. St. Elizabeth’s<br />

Psychiatric Hospital volunteer, University Community Concerts Usher<br />

Publications<br />

Peer-Reviewed Journal Articles:<br />

• Anderson G, Yang L, Falvey D. Photogenerated Arylnitrenium Ions:<br />

Photoisomerization of N-tert-Butyl-3-methylanthranilium Ion and Spin-Selective<br />

<strong>YANG</strong>, Page 4 of 6


Reactivity of the Isomeric Arylnitrenium Ion. Journal of the American Chemical<br />

Society. 115: 7254-7262 (1993)<br />

• Robbins R, Yang L, Anderson G, Falvey D. Photogenerated Arylnitrenium Ions:<br />

Reactions of N-tert-Butyl (2-Acetyl-4-substituted) phenyl Nitrenium Ions with<br />

Alcohols and Water Studied by Laser Flash Photolysis. Journal of the American<br />

Chemical Society. 117: 6544-6552 (1995)<br />

• Yang L, Sym M, Kenyon C. The roles of Two C. elegans HOX Co-factor Orthologs<br />

in Cell Migration and Vulva Development. Development. 132: 1413-1428 (2005)<br />

• Cha S, Yang L, Johnson G, Lai A, Chen M, Tihan R, Wendland MF, Dillon WP.<br />

Comparison of Microvascular Permeability Measurements, K trans , Determined with<br />

Conventional Steady-State T1-Weighted and First-Pass T2*-Weighted MR Imaging<br />

Methods in Gliomas and Meningiomas. American Journal of Neuroradiology. 27:<br />

409-417 (2006)<br />

• Casanova R, Ryali S, Serences J, Yang L, Kraft R, Laurienti PJ, Maldjian JA. The<br />

Impact of Temporal Regularization on Estimates of the BOLD Hemodynamic<br />

Response Function: A Comparative Analysis. Neuroimage, 40(4): 1606-18 (2008)<br />

• Addicott M, Yang L, Peiffer A, Burnett L, Burdette J, Chen M, Hayasaka S, Kraft R,<br />

Maldjian JA, Laurienti PJ. The Effect of Daily Caffeine Use on Cerebral Blood Flow:<br />

How Much Caffeine Can We Tolerate? Human Brain Mapping (in press).<br />

• Casanova R, Yang L, Hairston D, Laurienti PJ, Maldjian JA. Evaluating the impact<br />

of spatio-temporal smoothness constraints on the BOLD hemodynamic response<br />

function estimation: an analysis based on Tikhonov regularization. submitted to<br />

Neuroimage.<br />

• Addicott M, Yang L, Laurienti PJ. Caffeine and Blood Pressure: Acute effects in a<br />

"native" caffeinated state. submitted to Psychosomatic Medicine.<br />

• Addicott M, Yang L, Peiffer A, Laurienti PJ. Methodological Considerations for the<br />

Quantification of Self-Reported Caffeine Use. submitted to Psychopharmacology.<br />

• Tan H, Maldjian JA, Pollock J, Burdette J, Deibler A, Yang L, Kraft R. A Fast,<br />

Effective Filtering Method for Improving Clinical Pulsed Arterial Spin Labeling MRI.<br />

submitted to JMRI.<br />

• Yang L and Laurienti PJ. Caffeine and cerebral perfusion: implications for research<br />

and clinical imaging. submitted to J Cereb Blood Flow & Metabolism.<br />

Presentations<br />

Conferences:<br />

• Yang L, Kenyon C. Two New Genes Required for Positioning QR Descendants<br />

Along the Anterior-Posterior Body Axis. West Coast Worm Meeting, Berkeley, CA,<br />

USA. June 1998 (Poster)<br />

• Yang L, Sym M, Ch’ng Q, Kenyon C. Two New Genes Regulating Neuroblast<br />

Migration in C. elegans. West Coast Worm Meeting, Los Angeles, CA, USA. June<br />

2000 (Poster)<br />

• Yang L, Sym M, Kenyon C. Hox Cofactors CEH-20 and UNC-62 Regulate<br />

Neuroblast Migration in C. elegans. Santa Cruz Conference on Developmental<br />

Biology, Santa Cruz, CA, USA. 2000 (Poster)<br />

<strong>YANG</strong>, Page 5 of 6


• Yang L, Sym M, Kenyon C. Hox Cofactors CEH-20 and UNC-62 Regulate<br />

Neuroblast Migration in C. elegans. Cold Spring Harbor Symposium on Cell<br />

Migration and Axon Guidance, Cold Spring Harbor, NY, USA. 2000 (Poster)<br />

• Yang L, Cha S, Johnson G, Lai A, Wendland MF, Dillon WP. Comparison of<br />

Endothelial Permeability Surface Area Product, K trans , Derived by Steady-State T1<br />

and First-Pass T2* Methods for Brain Tumors. American Society for Neuroradiology<br />

Meeting, Seattle, WA, USA. June 2004 (Oral)<br />

• Yang L, Cha S, Johnson G, Lai A, Wendland MF, Dillon WP. Comparison of<br />

Endothelial Permeability Surface Area Product, K trans , Derived by Steady-State T1<br />

and First-Pass T2* Methods for Brain Tumors. International Society for Magnetic<br />

Resonance in Medicine Meeting, Kyoto, Japan. May 2004 (Oral)<br />

• Yang L, Lupo J, Oh J, Mayo M, Chang J, Han ET, Pelletier D, Nelson S, Cha S.<br />

Quantitative 3.0 Tesla Perfusion MRI of Deep Gray Matter in Multiple Sclerosis<br />

Patients: Correlation with Disease Status. International Society for Magnetic<br />

Resonance in Medicine Meeting, Miami Beach, FL, USA. May 2005 (Poster)<br />

• Burnett L, Kraft R, Maldjian J, Burdette J, Chen M, Yang L, Laurienti P. Caffeine<br />

Induces BOLD Signal Decreases in Subjects Without Pre-scan Withdrawal.<br />

Organization for Human Brain Mapping Conference, Florence, Italy. June 2006<br />

(Poster)<br />

• Addicott M, Peiffer A, Yang L, Kraft R, Maldjian J, Burdette J, Burnett L, Chen M,<br />

Laurienti P. The Effects of Caffeine on Cerebral Perfusion in Withdrawal and Native<br />

States. Organization for Human Brain Mapping Conference, Chicago, IL, USA. June<br />

2007 (Poster)<br />

• Yang L, Peiffer A, Addicott M, Kraft R, Maldjian J, Burdette J, Burnett L, Chen M,<br />

Laurienti P. BOLD Signal Decreases Following Caffeine Challenge in Individuals<br />

Who Intake High Daily Doses of Caffeine. Organization for Human Brain Mapping<br />

Conference, Chicago, IL, USA. June 2007 (Poster)<br />

• Yang L, Casanova R, Peiffer A, Addicott M, Kraft R, Maldjian J, Burdette J,<br />

Hayasaka S, Burnett L, Chen M, Laurienti P. Evaluating BOLD Signal Time Course<br />

in Pharmacological Functional MRI. Society for Neuroscience Meeting, San Diego,<br />

CA, USA. November 2007 (Oral)<br />

• Addicott M, Yang L, Peiffer A, Kraft RA, Maldjian JA, Burdette JH, Hayasaka S,<br />

Burnett L, Chen M, Laurienti PJ. The effects of chronic caffeine use on the temporal<br />

dynamics of the BOLD signal. Organization for Human Brain Mapping Conference,<br />

Melbourne, Australia. June 2008 (Poster)<br />

• Yang L, Addicott M, Peiffer A, Kraft RA, Maldjian JA, Burdette JH, Burnett L, Chen<br />

M, Laurienti PJ. Caffeine is not a universal BOLD contrast booster. Organization for<br />

Human Brain Mapping Conference, Melbourne, Australia. June 2008 (Poster)<br />

• Yang L, Wilson T, Leuthold A, Casanova R, Pardo P, Laurienti P, Lewis S,<br />

Georgopoulos A. Spatiotemporal gamma frequency activations distinguish semantic<br />

processes engaged by words and pseudowords. International Conference on<br />

Biomagnetism, Sapporo, Japan. August 2008 (Poster)<br />

Invited Lecture:<br />

• Yang L. Visualizing the effects of caffeine on the brain. Center for Design<br />

Innovation, Winston-Salem, NC, USA. Sept 2007.<br />

<strong>YANG</strong>, Page 6 of 6

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