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Curriculum vitae Igor Jurak, Ph.D.

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<strong>Curriculum</strong> <strong>vitae</strong> <strong>Igor</strong> <strong>Jurak</strong>, <strong>Ph</strong>.D. 2010<br />

<strong>Igor</strong> <strong>Jurak</strong>, <strong>Ph</strong>.D.<br />

Harvard Medical School<br />

Department of Biological Chemistry<br />

and Molecular <strong>Ph</strong>armacology<br />

250 Longwood Avenue, SGM 309<br />

02115 Boston MA, USA<br />

tel: +1 617 432 1789<br />

igor_jurak@hms.harvard.edu<br />

Education<br />

<strong>Ph</strong>.D. University of Wuerzburg, Germany, September 2006<br />

Graduate school Target proteins, 2002-2006<br />

Dissertation “The Molecular Mechanism of Cytomegalovirus species<br />

specificity”.<br />

Graduate school, University of Zagreb, 1999-2002<br />

Molecular and cellular biology<br />

University of Zagreb, 1993-1998<br />

Faculty of Biology, Molecular biology<br />

Professional<br />

Experience<br />

Harvard Medical School ; 2007 -<br />

Biological Chemistry and Molecular <strong>Ph</strong>armacology Department<br />

Postdoctoral fellow in Don Coen’s laboratory – research in the area of herpesviruses<br />

and microRNAs.<br />

Robert Koch Institute, Berlin, Germany; 2006-2007<br />

Division of Viral Infections<br />

Postdoctoral fellow in Wolfram Brune’s laboratory – specific interest in the molecular<br />

mechanisms of inhibition of apoptosis by cytomegalovirus.<br />

Rudolf Virchow Center for Experimental Biomedicine, Wuerzburg,<br />

Germany; 2002-2006<br />

Graduate student in Wolfram Brune’s laboratory – investigating molecular mechanisms<br />

of the cytomegalovirus species specificity.<br />

Rudjer Boskovic Institute, Zagreb, Croatia; 1999-2002<br />

Division of Molecular Medicine<br />

Graduate student in Koraljka Gall-Troselj and Oliver Vugrek groups – development of<br />

a diagnostic test for detection of pathogenic bacteria in periodontal pockets.<br />

Implementation of the recombinant technology into molecular medicine.


<strong>Curriculum</strong> <strong>vitae</strong> <strong>Igor</strong> <strong>Jurak</strong>, <strong>Ph</strong>.D. 2010<br />

Mentoring<br />

Experience<br />

Leah Silverstein (2009), Harvard Program in Biological and Biomedical<br />

Sciences<br />

- graduate student rotation (3 months)<br />

Hui Jun Lim (2008), Harvard Program in Virology.<br />

- graduate student rotation (3 months)<br />

Xiu-Jie Wang (2008), Harvard Program in Virology.<br />

- graduate student rotation (3 months)<br />

Margarita Krivitski (2008), Harvard College.<br />

- undergraduate student summer fellowship (3 months)<br />

Kerstin Heyl (2006), Humboldt University of Berlin, Germany.<br />

- undergraduate student pre-thesis (6 months)<br />

Susanne Yung (2004), University of Wuerzburg, Germany.<br />

- B.C. thesis in Biomedicine (6 months)<br />

Professional<br />

Awards<br />

The best presentation at 2 nd Croatian Congress of Microbiology<br />

With International Participation; Brijuni, Croatia, 2000.<br />

Languages<br />

Croatian<br />

English<br />

Speaking and writing knowledge of German


<strong>Curriculum</strong> <strong>vitae</strong> <strong>Igor</strong> <strong>Jurak</strong>, <strong>Ph</strong>.D. 2010<br />

Peer-review publications<br />

13. Kramer MF, <strong>Jurak</strong> I, Boissel S, Pesola JM, Knipe DM, Coen DM. Expression of herpes simplex virus 1<br />

microRNAs miR-H1 - miR-H6 during productive and latent infection. Submited.<br />

12. Schumacher U, Handke W, <strong>Jurak</strong> I, Brune W. Mutations in the M112/M113-coding region facilitate murine<br />

cytomegalovirus replication in human cells.<br />

J Virol. 2010 Aug;84(16):7994-8006.<br />

11. <strong>Jurak</strong> I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM.<br />

Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. J Virol. 2010<br />

May;84(9):4659-72.<br />

10. Kamil JP, Hume AJ, <strong>Jurak</strong> I, Münger K, Kalejta RF, Coen DM.<br />

Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human<br />

cytomegalovirus lacking UL97 protein kinase. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16823-8.<br />

9. Umbach JL, Kramer MF, <strong>Jurak</strong> I, Karnowski HW, Coen DM, Cullen BR.<br />

MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. Nature. 2008<br />

Aug 7;454(7205):780-3.<br />

8. <strong>Jurak</strong> I, Schumacher U, Simic H, Voigt S, Brune W.<br />

Murine cytomegalovirus m38.5 protein inhibits Bax-mediated cell death.<br />

J Virol. 2008 May;82(10):4812-22.<br />

7. Beluzić R, Cuk M, Pavkov T, Fumić K, Barić I, Mudd SH, <strong>Jurak</strong> I, Vugrek O.<br />

A single mutation at Tyr143 of human S-adenosylhomocysteine hydrolase renders the enzyme<br />

thermosensitive and affects the oxidation state of bound cofactor nicotinamide-adenine dinucleotide. Biochem<br />

J. 2006 Dec 1;400(2):245-53.<br />

6. <strong>Jurak</strong> I, Brune W.<br />

Induction of apoptosis limits cytomegalovirus cross-species infection.<br />

EMBO J. 2006 Jun 7;25(11):2634-42.<br />

5. Gall-Troselj K, Mravak-Stipetić M, <strong>Jurak</strong> I, Ragland WL, Pavelić J.<br />

Helicobacter pylori colonization of tongue mucosa--increased incidence in atrophic glossitis and burning<br />

mouth syndrome (BMS). J Oral Pathol Med. 2001 Oct;30(9):560-3.<br />

4. <strong>Jurak</strong> I, Ivic-Kardum M, Pavelic J, Gall-Troselj K<br />

Polymerase chain reaction (PCR) based detection of Streptococcus mitis and Leptotrichia buccalis from<br />

periodontal pockets. Periodicum Biologorum. 2001; 103:175-178.<br />

3. Gall-Troselj K, <strong>Jurak</strong> I, Mravak-Stipetic M, Pavelic J<br />

Importance of changed tongue mucosa for Helicobacter pylori colonization. Periodicum Biologorum.<br />

2001;103:149-151.<br />

2. Ivic-Kardum M, <strong>Jurak</strong> I, Gall-Troselj K, Pavelic K<br />

The effect of scaling and root planning on the clinical and microbiological parameters of periodontal diseases.<br />

Acta stomatologica Croatica. 2001;35:33-42.<br />

1. Pavelić J, Gall-Troselj K, <strong>Jurak</strong> I, Mravak-Stipetić M.<br />

Helicobacter pylori in oral aphthous ulcers. J Oral Pathol Med. 2000 Nov;29(10):523-5

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