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February 2012 Drug Update Information - Pharmacy Benefits ...

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1 mg/mL, 4 mL vial (NDC 25021-0781-04)<br />

Granisetron Hydrochloride Injection, Teva<br />

0.1 mg/mL, 1 mL vial (NDC 00703-7891-01)<br />

1 mg/mL, 1 mL vial (NDC 00703-7971-03)<br />

1 mg/mL, 4 mL vial (NDC 00703-7973-01)<br />

Granisetron Hydrochloride Injection, Wockhardt<br />

1 mg/mL, 1 mL vial (NDC 64679-0661-03)<br />

1 mg/mL, 4 mL vial (NDC 64679-0661-02)<br />

Kytril Injection, Roche<br />

1 mg/mL, 4 mL vial (NDC 00004-0240-09) - discontinued<br />

Reason for the Shortage<br />

Akorn discontinued granisetron 0.1 mg/mL 1 mL vials inn August, 2011. NDC codes changed<br />

for<br />

the 1 mg/ /mL presentations during this time period as well.<br />

Apotex, Baxter and Sandoz discontinued their granisetron hydrochloride presentations.<br />

APP states the shortage is due to manufacturing delays.<br />

Bedford discontinuedd granisetronn in May, 2011 to concentrate on the<br />

manufacturing of other<br />

products.<br />

Roche discontinued Kytril 0.1 mg/mL and 1 mg/mL 1 mL vials in October, 2009. They<br />

discontinued the 1 mg/mL 4 mL vials in July<br />

2010.<br />

Teva states the shortage is due to<br />

manufacturing delays.<br />

Wockhardt discontinued granisetron hydrochloride injection 0.1 mg/ /mL 1 mL vials in early,<br />

2010.<br />

Sagent cannot provide a reason for the shortage.<br />

Article link: http://www.ashp.org/<strong>Drug</strong>Shortages/Current/Bulletin.aspx?id=633<br />

Source: http://www.a<br />

ashp.org<br />

Diazepam<br />

Injectionn<br />

<strong>February</strong><br />

3, <strong>2012</strong><br />

Products Affected - Description<br />

Diazepam<br />

injection 5 mg/mL, Hospira<br />

2 mL Carpuject Luer-Lock syringes, package<br />

of 10 (NDC<br />

00409-1273-32)<br />

2 mL iSecure syringes, package of 10 (NDC 00409-1273-05)<br />

10 mL vials, package<br />

of 10 (NDC<br />

00409-3213-12)<br />

Reason for the Shortage<br />

Hospira has diazepam<br />

on back order due to manufacturin<br />

ng delays.<br />

Hospira is the sole supplier of diazepam injection.<br />

Article link: http://www.ashp.org/<strong>Drug</strong>Shortages/Current/Bulletin.aspx?id=492<br />

Source: http://www.a<br />

ashp.org<br />

Bumetanide Injection<br />

<strong>February</strong><br />

3, <strong>2012</strong><br />

Products Affected - Description<br />

Bumetanide 0.25 mg/mL, West-Ward<br />

2mL vial<br />

(NDC 10019-0506-45)<br />

Bumetanide 0.25 mg/mL, Bedford<br />

2 mL vial (NDC 55390-0500-02)<br />

4 mL vial (NDC 55390-0500-05)<br />

10 mL vial (NDC 55390-0500-10)<br />

Bumetanide 0.25 mg/mL, Hospira<br />

4 mL vial (NDC 00409-1412-04)<br />

53

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