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Pharmacoengineering Program - UNC/NCSU Joint Department of ...

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Sam Lai<br />

Philip Smith<br />

Assistant Pr<strong>of</strong>essor<br />

Associate Pr<strong>of</strong>essor<br />

Infectious diseases; drug delivery to and<br />

imaging <strong>of</strong> metastatic tumors<br />

Division Director <strong>of</strong> Graduate<br />

Admission and Graduate Studies<br />

Division Vice Chair<br />

pharmacy.unc.edu/<br />

samlai<br />

pharmacy.unc.edu/<br />

philipsmith<br />

Pharmacokinetics and drug metabolism,<br />

primarily glucuronidation. Study <strong>of</strong> quantitative<br />

proteomic LC-MS methods <strong>of</strong> proteins<br />

involved in drug disposition<br />

Weili Lin<br />

Andrew Wang<br />

pharmacy.unc.edu/<br />

weililin<br />

pharmacy.unc.edu/<br />

russellmumper<br />

Director, Biomedical Research<br />

Imaging Center<br />

Dixie Lee Boney Soo Distinguished<br />

Pr<strong>of</strong>essor <strong>of</strong> Neurological Medicine<br />

Non-invasive multi-modality imaging for<br />

guiding and monitoring therapeutic<br />

interventions.<br />

Russell Mumper<br />

John A. McNeill Distinguished Pr<strong>of</strong>essor<br />

Vice Dean<br />

Nanoparticles and other novel drug delivery<br />

technologies to treat or prevent cancer and<br />

infectious diseases<br />

nccancerhospital.<br />

org/members/<br />

andrew-wang<br />

pharmacy.unc.edu/<br />

xiaoxiao<br />

Assistant Pr<strong>of</strong>essor <strong>of</strong> Radiation<br />

Oncology<br />

Development and application <strong>of</strong> nanoparticle<br />

therapeutics in cancer treatment; development<br />

<strong>of</strong> 3D in vitro tumor models <strong>of</strong> cancer<br />

metastasis that reflects organ specificity<br />

Xiao Xiao<br />

Fred Eshelman Distinguished Pr<strong>of</strong>essor<br />

Molecular medicine, specifically gene<br />

delivery and therapy for various genetic<br />

and acquired diseases<br />

Admissions<br />

Admission is competitive. Over the last five years,<br />

GRE scores for those accepted average in the<br />

eighty-fifth and eighty-eighth percentiles for the<br />

verbal and quantitative sections, respectively.<br />

Teaching and research assistantships provide an<br />

annual stipend <strong>of</strong> $27,500 plus in-state tuition<br />

and health-insurance coverage.<br />

Qualified applicants will also receive the Molecular<br />

Pharmaceutics Scholar Fellowship, which provides<br />

a $3,000 supplement to the first-year stipend and<br />

may be extended to the second year.<br />

Molecular<br />

Pharmaceutics<br />

including an emphasis on<br />

<strong>Pharmacoengineering</strong><br />

Facilities<br />

• MOPH faculty and students work in 22,000<br />

square feet <strong>of</strong> lab space, most <strong>of</strong> it newly<br />

constructed or renovated since 2008.<br />

• Genetic Medicine Building: Completed in 2008 and<br />

shared with the <strong>UNC</strong> School <strong>of</strong> Medicine, the GMB<br />

contains 75,000 square feet <strong>of</strong> the School’s lab space.<br />

• Image Research Building: Scheduled to open in<br />

2014 across the street from the GMB, the IRB will<br />

add an additional 75,000 square feet <strong>of</strong> lab space<br />

to the <strong>UNC</strong> Eshelman School <strong>of</strong> Pharmacy, bringing<br />

the total to approximately 225,000 square feet.<br />

• Carolina <strong>of</strong>fers outstanding shared instruments<br />

and state-<strong>of</strong>-the-art core facilities.<br />

Contact<br />

Admissions information at<br />

go.unc.edu/pharmdoc<br />

Philip Smith, PhD<br />

Division Director <strong>of</strong> Graduate Studies<br />

pcs@email.unc.edu<br />

919-962-0095<br />

Division <strong>of</strong> Molecular Pharmaceutics<br />

pharmacy.unc.edu/moph/phd-program


Our Faculty Sets Us Apart<br />

Elena Batrakova<br />

Zhen Gu<br />

Rudy Juliano<br />

The MOPH faculty includes developers <strong>of</strong> a number <strong>of</strong> novel, patented<br />

drug-delivery systems; NIH study section members; entrepreneurs;<br />

editorial board members; and authors <strong>of</strong> hundreds <strong>of</strong> scholarly works.<br />

Our faculty is highly collaborative and entrepreneurial, having applied<br />

for eighteen patents based on their research and establishing seven<br />

new pharmaceutical and biotech companies in recent years.<br />

Associate Pr<strong>of</strong>essor<br />

Living cells as drug delivery vehicles for<br />

treatment <strong>of</strong> neurodegenerative disorders<br />

Assistant Pr<strong>of</strong>essor<br />

Integrating biomaterials design, biomolecular<br />

engineering and micro/nan<strong>of</strong>abrication<br />

toward on-demand drug delivery focused on<br />

cancer, diabetes, and regenerative medicine<br />

Boshamer Distinguished Pr<strong>of</strong>essor<br />

Regulation <strong>of</strong> signal transduction and cell<br />

growth by integrin-mediated cell adhesion,<br />

therapeutic drug design and delivery<br />

The faculty comprises eleven tenure-track faculty and ten research<br />

faculty. Our tenure-track faculty members have averaged more than<br />

$800,000 each in annual research funding over the last four years.<br />

pharmacy.unc.edu/<br />

elenabatrakova<br />

www.bme.unc.edu/<br />

labs/gulab<br />

pharmacy.unc.edu/<br />

rudyjuliano<br />

Michael Jay<br />

Paul Dayton<br />

Shawn Hingtgen<br />

Alexander Kabanov<br />

pharmacy.unc.edu/<br />

michaeljay<br />

Fred Eshelman Distinguished Pr<strong>of</strong>essor<br />

Division Chair<br />

Solving problems in nuclear imaging and<br />

therapy and in the development <strong>of</strong> novel<br />

formulations and drug delivery systems<br />

pharmacy.unc.edu/<br />

pauldayton<br />

Pr<strong>of</strong>essor, <strong>UNC</strong>/<strong>NCSU</strong> <strong>Joint</strong> <strong>Department</strong><br />

<strong>of</strong> Biomedical Engineering<br />

Associate Director for Education, <strong>UNC</strong><br />

Biomedical Research Imaging Center<br />

Developing new technologies for imaging<br />

blood flow, microvasculature and molecular<br />

markers using ultrasound and microbubble<br />

contrast agents<br />

pharmacy.unc.edu/<br />

shawnhingtgen<br />

Assistant Pr<strong>of</strong>essor<br />

Harnessing the power <strong>of</strong> stem cells and<br />

molecular imaging to develop and translate<br />

innovative cancer therapies<br />

pharmacy.unc.edu/<br />

alexanderkabanov<br />

Mescal S. Ferguson Distinguished<br />

Pr<strong>of</strong>essor<br />

Director, Center for Nanotechnology<br />

in Drug Delivery<br />

Enabling technologies using polymers,<br />

magnets, small drugs and biotherapeutics<br />

to treat cancer, brain and other diseases<br />

Nancy Allbritton<br />

Joseph DeSimone<br />

Leaf Huang<br />

Richard Kowalsky<br />

chem.unc.edu/<br />

people/faculty/<br />

allbritton<br />

Debreczeny Distinguished Pr<strong>of</strong>essor<br />

Pr<strong>of</strong>essor and Chair, <strong>UNC</strong>/<strong>NCSU</strong> <strong>Joint</strong><br />

<strong>Department</strong> <strong>of</strong> Biomedical Engineering<br />

Director, Curriculum <strong>of</strong> Applied<br />

Science and Engineering<br />

Signaling in single cells, micr<strong>of</strong>abricated<br />

systems for cellular analysis<br />

pharmacy.unc.edu/<br />

josephdesimone<br />

Director, Frank Hawkins Kenan Institute<br />

<strong>of</strong> Private Enterprise<br />

Chancellor’s Eminent Pr<strong>of</strong>essor <strong>of</strong><br />

Chemistry, <strong>UNC</strong><br />

William R. Kenan, Jr. Distinguished Pr<strong>of</strong>essor<br />

<strong>of</strong> Chemical Engineering, <strong>NCSU</strong><br />

New medicines and vaccines; nanomedicine;<br />

medical devices; entrepreneurship<br />

pharmacy.unc.edu/<br />

leafhuang<br />

Fred Eshelman Distinguished Pr<strong>of</strong>essor<br />

Development <strong>of</strong> non-viral vectors for gene<br />

(including oligonucleotides) therapy; receptor<br />

mediated drug and vaccine targeting<br />

using self-assembled nanoparticles<br />

pharmacy.unc.edu/<br />

richardkowalsky<br />

Associate Pr<strong>of</strong>essor<br />

Application <strong>of</strong> radioactivity and radioactive<br />

drugs to solve clinical research problems<br />

Molecular Pharmaceutics at Carolina<br />

Molecular pharmaceutics deals with delivering<br />

and maintaining the desired amount <strong>of</strong> a therapeutic<br />

agent at a target site for a specific period<br />

<strong>of</strong> time. This discipline is crucial to turning new<br />

molecular entities into safe and effective drugs.<br />

<strong>Pharmacoengineering</strong><br />

In collaboration with the <strong>UNC</strong>-<strong>NCSU</strong> <strong>Joint</strong> <strong>Department</strong><br />

<strong>of</strong> Biomedical Engineering, MOPH <strong>of</strong>fers the<br />

PhD program in pharmaceutical sciences with an emphasis<br />

on pharmacoengineering, which integrates engineering<br />

methods with pharmaceutical sciences.<br />

pharmacy.unc.edu/pharmacoengineering<br />

Center for Nanotechnology<br />

in Drug Delivery<br />

MOPH is home to the Center for Nanotechnology in<br />

Drug Delivery directed by Mescal S. Ferguson Distinguished<br />

Pr<strong>of</strong>essor Alexander “Sasha” Kabanov, PhD.<br />

The center focuses on improving human health by<br />

safely and effectively translating new drug and imaging<br />

discoveries into clinical trials using nanotechnology.<br />

The center creates and develops cutting-edge,<br />

nanotechnology-based drug- and imaging-delivery<br />

systems; facilitates drug discovery and identification<br />

<strong>of</strong> drug leads; and formulates and characterizes the<br />

identified preclinical and clinical leads for testing.<br />

pharmacy.unc.edu/cndd

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