Strategies for the Prevention of Postherpetic Neuralgia - immpact
Strategies for the Prevention of Postherpetic Neuralgia - immpact
Strategies for the Prevention of Postherpetic Neuralgia - immpact
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Preventing PHN by attenuating nerve<br />
damage and acute pain in herpes zoster<br />
VZV<br />
reactivation<br />
Peripheral nerve damage and dysfunction<br />
Acute neuropathic pain<br />
VZV<br />
replication<br />
ANTIVIRAL<br />
THERAPY<br />
ANALGESIA<br />
Acute nociceptive pain<br />
Central<br />
functional and<br />
structural<br />
changes (e.g.,<br />
central<br />
sensitization,<br />
damage from<br />
excitotoxicity)<br />
PHN<br />
Tissue damage and inflammation<br />
VZV = varicella-zoster virus<br />
Dworkin RH, et al. Clinical Journal <strong>of</strong> Pain, 2000;16:S90-S100.