DETERGENTS AND THEIR PROPERTIES BEN HANKAMER ... - 2dx

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FROM TISSUE TO PROTEIN SEIBERT ET AL 1987 J CELL BIOL 105:2257
DETERGENT DEFINITION DETERGENTS ARE AMPHIPATHIC MOLECULES THAT CONTAIN BOTH A POLAR (HEADGROUP) AND HYDROPHOBIC REGIONS (TAIL). PLAY AN IMPORTANT ROLE IN: 1. POLAR HEADGROUPS FORM HYDROGEN BONDS WITH WATER. 2. HYDROPHOBIC TAILS DO NOT FORM H-BONDS WITH H 2 O….THEREFORE AGGREGATE INTO MICELLES. 3. DETERGENTS REPLACE LIPIDS DURING SOLUBILIZATION AND STABILIZE TRANS-MEMBRANE DOMAINS IN SOLUTION. PURIFICATION STABILIZATION CRYSTALLIZATION SEIBERT ET AL 1987 J CELL BIOL 105:2257
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DETERGENTS AND THEIR PROPERTIES BEN HANKAMER ... - 2dx

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