Global Sequence Alignment: the Needleman-âWunsch Algorithm
Global Sequence Alignment: the Needleman-âWunsch Algorithm
Global Sequence Alignment: the Needleman-âWunsch Algorithm
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Implicit Column Scoring FuncLon <br />
• 1, match <br />
• 0, mismatch (mutaLon) <br />
• 0, gap (inserLon, deleLon) <br />
ASLVN-DK!<br />
A-LVNKDK!<br />
10111011=6!<br />
• Sum <strong>the</strong> score over all columns of alignment. <br />
Deriving more complex scoring schemes will be a main <br />
topic of my next lecture.