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73 Albinism and Other Genetic Disorders of Pigmentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 781 Thomas J. Hornyak, MD, PhD 85 Disorders of the Apocrine Sweat Glands . . . . . . 947 Christos C. Zouboulis, MD, PhD & Fragkiski Tsatsou, MD, MSc, BSc Contents 74 Vitiligo . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 792 Stanca A. Birlea, MD, PhD, Richard A. Spritz, MD & David A. Norris, MD 75 Hypomelanoses and Hypermelanoses . . . . . . . 804 Hilde Lapeere, MD, PhD, Barbara Boone, MD, PhD, Sofie De Schepper, MD, PhD, Evelien Verhaeghe, MD, Mireille Van Gele, PhD, Katia Ongenae, MD, PhD, Nanja Van Geel, MD, PhD, Jo Lambert, MD, PhD, & Lieve Brochez, MD, PhD Section 12. Disorders of the Oral and Genital Integument 76 Biology and Pathology of the Oral Cavity . . . . . 827 Sook-Bin Woo, DMD 77 Diseases and Disorders of the Male Genitalia . . 852 Christopher B. Bunker, MD, FRCP Section 15. Disorders of the Hair and Nails 86 Biology of Hair Follicles . . . . . . . . . . . . . . . . . . . . .960 George Cotsarelis, MD & Vladimir Botchkarev, MD, PhD 87 Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes . . . . . . . . . . . . . . .973 Paradi Mirmirani, MD & Maureen Rogers, MBBS, FACD 88 Hair Growth Disorders . . . . . . . . . . . . . . . . . . . . . 979 Nina Otberg, MD & Jerry Shapiro, MD, FRCPC, FAAD 89 Biology of Nails and Nail Disorders . . . . . . . . . 1009 Antonella Tosti, MD & Bianca Maria Piraccini, MD, PhD viii 78 Diseases and Disorders of the Female Genitalia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 878 Lynette J. Margesson, MD, FRCPC & F. William Danby, MD, FRCPC, FAAD PART 3 Disorders of the Skin Appendages Section 13. Disorders of the Sebaceous Glands 79 Biology of Sebaceous Glands . . . . . . . . . . . . . . . . .893 Amanda M. Nelson, PhD & Diane M. Thiboutot, MD 80 Acne Vulgaris and Acneiform Eruptions . . . . . . 897 Andrea L. Zaenglein, MD, Emmy M. Graber, MD, & Diane M. Thiboutot, MD 81 Rosacea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 918 Michelle T. Pelle, MD 82 Perioral Dermatitis . . . . . . . . . . . . . . . . . . . . . . . . . 925 Leslie P. Lawley, MD & Sareeta R.S. Parker, MD Section 14. Disorders of the Eccrine and Apocrine Glands 83 Biology of Eccrine and Apocrine Glands . . . . . . 929 Theodora M. Mauro, MD 84 Disorders of the Eccrine Sweat Glands and Sweating . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 936 Robert D. Fealey, MD & Adelaide A. Hebert, MD PART 4 Disorders Due to the Environment Section 16. Disorders Due to Ultraviolet Radiation 90 Fundamentals of Cutaneous Photobiology and Photoimmunology . . . . . . . . . . . . . . . . . . . . . . . . 1031 Irene E. Kochevar, PhD, Charles R. Taylor, MD, & Jean Krutmann, MD 91 Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and Photoexacerbated . . . . . . . . . . . . . . . . . . . . . . . . . 1049 Travis W. Vandergriff, MD & Paul R. Bergstresser, MD 92 Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents . . . . . . . . . . . . . . . . . . . . . . . . 1066 Henry W. Lim, MD Section 17. Skin Changes Due to Other Physical and Chemical Factors 93 Thermoregulation . . . . . . . . . . . . . . . . . . . . . . . . 1075 Dean L. Kellogg, Jr., MD, PhD 94 Cold Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1079 Gérald E. Piérard, MD, PhD, Pascale Quatresooz, MD, PhD, & Claudine Piérard-Franchimont, MD, PhD
95 Thermal Injuries . . . . . . . . . . . . . . . . . . . . . . . . . . 1089 Robert L. Sheridan, MD 96 Skin Problems in Amputees . . . . . . . . . . . . . . . . 1095 Calum C. Lyon, MA, FRCP & Michael H. Beck, FRCP, MBChB 108 Skin Changes and Diseases in Pregnancy . . . . 1204 Julie K. Karen, MD & Miriam Keltz Pomeranz, MD 109 Aging of Skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1213 Mina Yaar, MD & Barbara A. Gilchrest, MD 97 Skin Problems in Ostomates . . . . . . . . . . . . . . . 1104 Calum C. Lyon, MA, FRCP & Michael H. Beck, FRCP, MBChB 98 Corns and Calluses . . . . . . . . . . . . . . . . . . . . . . . . 1111 Thomas M. DeLauro, DPM & Nicole M. DeLauro, DPM 99 Sports Dermatology . . . . . . . . . . . . . . . . . . . . . . . 1115 Dirk M. Elston, MD 100 Decubitus (Pressure) Ulcers . . . . . . . . . . . . . . . 1121 Jennifer G. Powers, MD, Lillian Odo, MD, & Tania J. Phillips, MD, FRCP, FRCPC 101 Body Art . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1129 Anne Laumann, MBChB, MRCP(UK), FAAD PART 5 Neurocutaneous and Psychocutaneous Aspects of Skin Disease PART 7 NEOPLASIA Section 20. Carcinogenesis 110 Genome Instability, DNA Repair, and Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1227 Thomas M. Rünger, MD, PhD & Kenneth H. Kraemer, MD 111 Chemical Carcinogenesis . . . . . . . . . . . . . . . . . . 1239 Adam B. Glick, PhD & Andrzej A. Dlugosz, MD 112 Ultraviolet Radiation Carcinogenesis . . . . . . . 1251 Masaoki Kawasumi, MD, PhD & Paul Nghiem, MD, PhD Section 21. Epidermal and Appendageal Tumors 113 Epithelial Precancerous Lesions . . . . . . . . . . . . 1261 Karynne O. Duncan, MD, John K. Geisse, MD & David J. Leffell, MD Contents Section 18. Neurocutaneous and Psychocutaneous Skin Disease 102 Neurobiology of the Skin . . . . . . . . . . . . . . . . . . 1137 Martin Steinhoff, MD, PhD & Thomas A. Luger, MD 103 Pathophysiology and Clinical Aspects of Pruritus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1146 Gil Yosipovitch, MD & Tejesh S. Patel, MBBS (Lon), BSc (Hons) 104 Psychocutaneous Skin Disease . . . . . . . . . . . . . 1158 Evan Rieder, MD & Francisco A. Tausk, MD 105 Cutaneous Manifestations of Drug Abuse . . . . 1166 Haley Naik, MD & Richard Allen Johnson, MDCM 106 Skin Signs of Physical Abuse . . . . . . . . . . . . . . . 1177 Howard B. Pride, MD PART 6 SKIN CHANGES ACROSS THE SPAN OF LIFE Section 19. From Birth to Old Age 107 Neonatal, Pediatric, and Adolescent Dermatology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1185 Mary Wu Chang, MD 114 Squamous Cell Carcinoma . . . . . . . . . . . . . . . . . 1283 Douglas Grossman, MD, PhD & David J. Leffell, MD 115 Basal Cell Carcinoma . . . . . . . . . . . . . . . . . . . . . 1294 John A. Carucci, MD, PhD, David J. Leffell, MD & Julia S. Pettersen, MD 116 Basal Cell Nevus Syndrome . . . . . . . . . . . . . . . 1304 Anthony E. Oro, MD, PhD & Jean Y. Tang, MD, PhD 117 Keratoacanthoma . . . . . . . . . . . . . . . . . . . . . . . . . 1312 Lorenzo Cerroni, MD & Helmut Kerl, MD 118 Benign Epithelial Tumors, Hamartomas, and Hyperplasias . . . . . . . . . . . . 1319 Valencia D. Thomas, MD, Nicholas R. Snavely, MD, Ken K. Lee, MD & Neil A. Swanson, MD 119 Appendage Tumors and Hamartomas of the Skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1337 Divya Srivastava, MD & R. Stan Taylor, MD 120 Merkel Cell Carcinoma . . . . . . . . . . . . . . . . . . . . 1362 Andrew Tegeder, MS, Olga Afanasiev, BA, & Paul Nghiem, MD, PhD 121 Mammary and Extramammary Paget’s Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . 1371 Sherrif F. Ibrahim, MD, PhD, Roy C. Grekin, MD, & Isaac M. Neuhaus, MD ix
Page 1 and 2: Contents Contributors .. . . . . .
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Page 7 and 8: 149 Mastocytosis . . . . . . . . .
Page 9 and 10: SECTION 32. Sexually Transmitted Di
Page 11: SECTION 41. Cosmetic Dermatology 25

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