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Hyperuricemia & Gout - Rhode Island Medical Society

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UNDER THE JOINT<br />

EDITORIAL SPONSORSHIP OF:<br />

The Warren Alpert <strong>Medical</strong> School of<br />

Brown University<br />

Edward J. Wing, MD, Dean of Medicine<br />

& Biological Science<br />

<strong>Rhode</strong> <strong>Island</strong> Department of Health<br />

David R. Gifford, MD, MPH, Director<br />

Quality Partners of <strong>Rhode</strong> <strong>Island</strong><br />

Richard W. Besdine, MD, Chief<br />

<strong>Medical</strong> Officer<br />

<strong>Rhode</strong> <strong>Island</strong> <strong>Medical</strong> <strong>Society</strong><br />

Vera A. DePalo, MD, President<br />

EDITORIAL STAFF<br />

Joseph H. Friedman, MD<br />

Editor-in-Chief<br />

Joan M. Retsinas, PhD<br />

Managing Editor<br />

Stanley M. Aronson, MD, MPH<br />

Editor Emeritus<br />

EDITORIAL BOARD<br />

Stanley M. Aronson, MD, MPH<br />

John J. Cronan, MD<br />

James P. Crowley, MD<br />

Edward R. Feller, MD<br />

John P. Fulton, PhD<br />

Peter A. Hollmann, MD<br />

Anthony E. Mega, MD<br />

Marguerite A. Neill, MD<br />

Frank J. Schaberg, Jr., MD<br />

Lawrence W. Vernaglia, JD, MPH<br />

Newell E. Warde, PhD<br />

OFFICERS<br />

Vera A. DePalo, MD<br />

President<br />

Gary Bubly, MD<br />

President-Elect<br />

Nitin S. Damle, MD<br />

Vice President<br />

Alyn L. Adrain, MD<br />

Secretary<br />

Jerald C. Fingerhut, MD<br />

Treasurer<br />

Diane R. Siedlecki, MD<br />

Immediate Past President<br />

DISTRICT & COUNTY PRESIDENTS<br />

Geoffrey R. Hamilton, MD<br />

Bristol County <strong>Medical</strong> <strong>Society</strong><br />

Robert G. Dinwoodie, DO<br />

Kent County <strong>Medical</strong> <strong>Society</strong><br />

Rafael E. Padilla, MD<br />

Pawtucket <strong>Medical</strong> Association<br />

Patrick J. Sweeney, MD, MPH, PhD<br />

Providence <strong>Medical</strong> Association<br />

Nitin S. Damle, MD<br />

Washington County <strong>Medical</strong> <strong>Society</strong><br />

Cover: Monosodium urate crystals aspirated<br />

from the subcutaneous tissue of a patient with<br />

cutaneous manifestations of gout and viewed<br />

with a polarized light microscope, by Bernard<br />

Zimmermann, MD, and Peter Libbey, MD<br />

Medicine Health<br />

VOLUME 92 NO. 11 November 2009<br />

R HODE I SLAND<br />

PUBLICATION OF THE RHODE ISLAND MEDICAL SOCIETY<br />

COMMENTARIES<br />

350 Medication Trials: In an Imperfect World: <strong>Gout</strong> and Parkinson’s Disease<br />

Joseph H. Friedman, MD<br />

351 An Ailment for the Royally Nourished<br />

Stanley M. Aronson, MD<br />

CONTRIBUTIONS<br />

SPECIAL ISSUE: <strong>Hyperuricemia</strong> and <strong>Gout</strong><br />

Guest Editor: Bernard Zimmermann, MD<br />

352 Introduction: <strong>Hyperuricemia</strong> and <strong>Gout</strong><br />

Bernard Zimmermann, MD<br />

353 <strong>Medical</strong> Implications of <strong>Hyperuricemia</strong><br />

Larissa Sachs, MD, Kerri L. Batra, MD, and Bernard Zimmermann, MD<br />

356 Diagnosis and Management of Acute <strong>Gout</strong><br />

Nazli Conway, MD, and Stuart Schwartz, MD<br />

359 Approach To the Treatment of <strong>Hyperuricemia</strong><br />

Samuel H. Poon, MD, Harald A. Hall, MD, and Bernard Zimmermann, MD<br />

363 <strong>Gout</strong> In Women<br />

Jill McClory, MD, and Nuha Said, MD<br />

369 Treatment Failure <strong>Gout</strong><br />

Saman Ali, MD, and Edward V. Lally, MD<br />

COLUMNS<br />

372 IMAGES IN MEDICINE: Intranasal Mucosal Malignant Melanoma<br />

Robert Bagdasaryan, MD, and Mark Andreozzi, DO<br />

373 ADVANCES IN PHARMACOLOGY: Use of Angiotensin-Converting Enzyme Inhibitors/<br />

Angiotensin Receptor Blockers and Lipid-lowering Therapies Among <strong>Rhode</strong><br />

<strong>Island</strong> With Diabetes Enrolled In Medicare Part D Plans in 2006 and 2007<br />

Stephen Kogut, PhD, MBA, RPh, Aisling Caffrey, PhD, and Lynn Pezzullo, RPh<br />

377 GERIATRICS FOR THE PRACTICING PHYSICIAN: Asymptomatic Versus Symptomatic<br />

Urinary Tract Infections In Long-Term-Care-Facility Residents<br />

Porpon Rotjanapan, MD, and David Dosa, MD, MPH<br />

379 PHYSICIAN’S LEXICON: The Wanderings of the Vagus Nerve<br />

Stanley M. Aronson, MD<br />

380 HEALTH BY NUMBERS: Diabetes Prevention and Control: Progress Towards Healthy<br />

People 2010 Goals<br />

Annie Gjelsvik, PhD, Dona Goldman, RN, MPH, and Marilyn Moy, RN, MSW<br />

382 POINT OF VIEW: Prevention of Relapsing Mediocrity: How To Maintain Performance<br />

Improvement In Hospitals<br />

John S. Coldiron, MD, MPH<br />

385 November Heritage<br />

Medicine and Health/<strong>Rhode</strong> <strong>Island</strong> (USPS 464-820), a monthly publication, is owned and published by the <strong>Rhode</strong> <strong>Island</strong> <strong>Medical</strong> <strong>Society</strong>, 235<br />

Promenade St., Suite 500, Providence, RI 02908, Phone: (401) 331-3207. Single copies $5.00, individual subscriptions $50.00 per year, and $100<br />

per year for institutional subscriptions. Published articles represent opinions of the authors and do not necessarily reflect the official policy of the <strong>Rhode</strong> <strong>Island</strong><br />

<strong>Medical</strong> <strong>Society</strong>, unless clearly specified. Advertisements do not imply sponsorship or endorsement by the <strong>Rhode</strong> <strong>Island</strong> <strong>Medical</strong> <strong>Society</strong>. Periodicals postage<br />

paid at Providence, <strong>Rhode</strong> <strong>Island</strong>. ISSN 1086-5462. POSTMASTER: Send address changes to Medicine and Health/<strong>Rhode</strong> <strong>Island</strong>, 235 Promenade St.,<br />

Suite 500, Providence, RI 02908. Classified Information: RI <strong>Medical</strong> Journal Marketing Department, P.O. Box 91055, Johnston, RI 02919,<br />

phone: (401) 383-4711, fax: (401) 383-4477, e-mail: rimj@cox.net. Production/Layout Design: John Teehan, e-mail: jdteehan@sff.net.<br />

VOLUME 92 NO. 11 NOVEMBER 2009<br />

349

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