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Volume Targeted Ventilation in Preterm Infants

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<strong>Volume</strong> <strong>Targeted</strong>-SIMV on Spontaneous<br />

Episodes of Hypoxemia <strong>in</strong> <strong>Preterm</strong> <strong>Infants</strong><br />

Polimeni et al. Biol Neonate 2006<br />

Crossover trial SIMV vs. VT-SIMV<br />

32 <strong>in</strong>fants with frequent episodes of hypoxemia<br />

GA 25 ± 1 wks, Age 38 ± 17 d<br />

Initial phase (n=12)<br />

SIMV vs. VG-SIMV with V T @ 45 4.5 ml/Kg<br />

‣ No effect on hypoxemia episodes<br />

Second phase (n=20)<br />

SIMV vs. VG-SIMV with V T @ 6.0 ml/Kg<br />

T

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