Autonomic Nervous System (ANS)

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4- Dopamine -It is immediate metabolic precursor of N.A occurs naturally in C.N.S in basal ganglia (function as N.T) and in adrenal medulla. - - Dopamine activates: 1- β1 Receptors (and at higher dose activate also a R.), 2- D1 & D2 R occur in peripheral mesenteric & renal vascular bed lead to vasodilatation.
Actions of Dopamine 1- C.V.S: Dopamine lead to increase force & rate of contraction of heart (β1 effect). 2- Renal and visceral: Dilatation of renal & splanchnic arterioles (D1,D2 agonist effect), which lead to increase blood flow to kidney & other viscera. Uses: Dopamine drug of choice (over A) in shock as A cause decrease renal blood supply & may cause renal shutdown. Overdose: Nausea, hypertension, arrhythmia.
Page 1 and 2: Autonomic Nervous System (ANS) د.
Page 3 and 4: Classifications of Adrenergic Agoni
Page 5 and 6: II- Indirect acting adrenergic agon
Page 7 and 8: I- Direct acting adrenergic agonist
Page 9 and 10: C.V.S effect of Adrenaline (Epineph
Page 11 and 12: Clinical uses of Adrenaline 1- Acut
Page 13 and 14: 5- Drug interaction with Adrenaline
Page 15 and 16: Action of Nor adrenaline (NA) C.V.S
Page 17 and 18: Notes: 1- Due to powerful vasoconst
Page 19: Action of Isoproterenol (Isoprenoli

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Autonomic Nervous System (ANS)