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Issue #2: Fall 2007 (pdf) - KU Endowment

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“Just running into each other in the hall, you share ideas. You have<br />

a problem, and you get it fixed in the hallway at the water cooler.”<br />

LISA STEHNO-BITTEL on the collaborative working environment at the Kansas Life Sciences Innovation Center<br />

LISA SCHELLER<br />

The Kansas Life Sciences Innovation Center, which opened<br />

in January, houses more than 300 researchers and staff. They<br />

collaborate in their research as they seek ways to prevent,<br />

treat and cure many serious diseases and medical conditions.<br />

Synergy at work<br />

To understand how diseases and the environment affect<br />

reproductive success, Michael Wolfe studies functions at the<br />

cellular and molecular levels. His laboratory is designed for<br />

many types of research — so scientists with related goals can<br />

work together easily.<br />

Broad view<br />

Diabetes is just one area of research at the life sciences<br />

innovation center, which opened in January in Kansas City,<br />

Kan. Every day, more than 300 researchers and staff are<br />

looking for ways to treat, cure or prevent serious diseases<br />

and medical conditions.<br />

At the corner of 39th Street and Rainbow Boulevard,<br />

the center stands tall and filled with light. It’s the newest<br />

addition to the <strong>KU</strong> Medical Center complex, symbolizing<br />

the Medical Center’s commitment to establishing itself as a<br />

world-class research center.<br />

The new building also symbolizes a partnership<br />

among the state of Kansas, the Medical Center and private<br />

philanthropy. Funding of the $57-million, 205,000-squarefoot<br />

facility resulted from an agreement between the state<br />

and the Medical Center. In addition, the Hall Family<br />

Foundation of Kansas City, Mo., donated $27 million for<br />

state-of-the-art laboratory equipment.<br />

Paul Terranova, the Medical Center’s vice chancellor<br />

for research, said the life sciences innovation center<br />

Joyce Slusser directs the Flow Cytometry Laboratory, one of the<br />

center’s research cores. Above, she uses laser light to analyze<br />

and detect differences between cells. The technology has many<br />

applications, including detection of cancer. A gift from the Hall<br />

Family Foundation provided the lab’s high-tech equipment.<br />

includes established programs, such as those in liver<br />

research, reproductive sciences and neuroscience, that<br />

draw significant grant funding. The building also houses<br />

emerging programs in diabetes management and in<br />

proteomics, the study of proteins and their functions.<br />

The center’s exceptional laboratory spaces and<br />

technology have enhanced recruitment efforts. Terranova<br />

estimated more than a third of the researchers are<br />

new. Moreover, the center was designed to increase<br />

communication among researchers by designating a<br />

separate research focus for each floor.<br />

“We thought if we had people together who could talk<br />

to each other, share research, share ideas, we could develop<br />

a certain degree of synergy so that the whole would be<br />

greater than the sum of its parts,” Terranova said.<br />

Though research is ongoing, it’s difficult to predict<br />

when the results of the findings will make it into<br />

mainstream medicine.<br />

“You never know,” Terranova said. “You could make a<br />

major discovery tomorrow, and it could have a major impact.”<br />

Designed to foster interaction, the center’s interior architecture<br />

includes conference rooms and informal seating areas as well as space<br />

for impromptu meetings. Here, Paul Terranova, <strong>KU</strong> Medical Center<br />

vice chancellor for research, confers with Yvonne Wan, one of the<br />

Medical Center’s leading liver researchers.<br />

Better lives<br />

This research eventually will make a difference in the lives<br />

of those diagnosed with many diseases, including diabetes.<br />

“Research today has already led me to a new drug that<br />

allows me to be free from insulin completely,” Butler Payne<br />

said. “I feel great and, with exercise, can manage my diabetes<br />

easily; think how far research can lead us in the future.”<br />

Stehno-Bittel appreciates how the life sciences center’s<br />

design helps researchers work together. “There is so much<br />

more collaboration among the groups here,” she said. “Just<br />

running into each other in the hall, you share ideas. You<br />

have a problem, and you get it fixed in the hallway at the<br />

water cooler.”<br />

HELP FIND A CURE<br />

To support any area of research at the Kansas Life Sciences<br />

Innovation Center, give online at kuendowment.org/medcenter<br />

or contact Stephanie Grinage at <strong>KU</strong> <strong>Endowment</strong>’s office at<br />

<strong>KU</strong> Medical Center, 1-888-588-5249.<br />

Fourth floor: Yvonne Wan leads researchers who study<br />

factors that control liver functions. Their work will lead<br />

to treatment and prevention of diseases such as alcoholic<br />

hepatitis, gallstones, liver cancer and diabetes.<br />

Third floor: Investigators led by Paul Terranova<br />

study male and female reproductive function as well as<br />

pregnancy. They also search for causes and treatments for<br />

diseases that cause infertility and ovarian cancer.<br />

Second floor: In the neuroscience center, directed<br />

by Peter Smith, researchers study the nervous system.<br />

Research is aimed at areas such as diabetes, disorders<br />

affecting hearing and balance, and female pain syndromes<br />

associated with estrogen (including migraine and<br />

fibromyalgia).<br />

First floor: Investigators in the proteomics program, led<br />

by Gerald Carlson, study proteins that make up the body<br />

and regulate cell function. Their work relates to various<br />

diseases, including cancer and Alzheimer’s.<br />

Ground floor: Dr. David Robbins directs the Diabetes<br />

Institute, where outpatients learn about nutrition and<br />

exercise in preventing and managing diabetes.<br />

Research cores: Twelve specialized laboratories provide<br />

the latest technology to all Medical Center researchers<br />

and other area research institutions.<br />

14 <strong>KU</strong> GIVING FALL <strong>2007</strong> kuendowment.org 15

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