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<strong>2.3.2009</strong><br />

<strong>CURRICULUM</strong> <strong>VITAE</strong><br />

Name: Mohammad Mehdi Aslani<br />

Address: Bacteriology Department, Pasteur Institute of Iran,<br />

Tehran 1316943551, Iran<br />

Tel: (+98-21) 6640 5535<br />

Fax: (+98-2) 6640 5535<br />

E-mail: mmaslani@pasteur.ac.ir<br />

mmaslani@Yahoo.com<br />

Nationality: Iranian<br />

Date of Birth: 24 Sep 1961<br />

Status: Married<br />

Position: Associated professor<br />

Education:<br />

1979 -1986: Bs in Biology, Tarbit Moalem University Tehran, Iran<br />

1986-1988: Military Service<br />

1989 to 1991: MSPH in Bacteriology,Tehran Medical Science University, Tehran,Iran<br />

1992 to 1998: Ph.D. of Medical Microbiology, Tehran Medical Science University, Tehran,Iran<br />

2000-2001: Bacteries Pathogen's Emergentes, Unite Biodiversite des Institute Pasteur of<br />

Paris,France, (Fellowship)<br />

1


Theses:<br />

1. MSPH Thesis: Rapid identification of group A streptococci by L-pyrolidonyl –B- naphtyl amide<br />

Hydrolysis. Tehran Medical University / Tehran/ Iran/ 1990-1991.<br />

2. PhD Thesis: Determination of verocytotoxin producing Escherichia coli in Mazandaran and Ilam<br />

provinces and the adherence pattern of isolated strains. Tehran Medical University /Tehran/Iran/<br />

1996-1998.<br />

Projects:<br />

1. 2007-2008: Molecular characterization and ribotyping of Pseudomonas spp isolated from inpatient<br />

of hospitals .Pasteur Institute of Iran.<br />

2. 2007-2008: Molecular characterization of Shigella spp isolated from diarrheal cases and<br />

asymptomatic persons. Pasteur Institute of Iran.<br />

3. 2005-2006: Prevalence of Diarrhoeal Diseases due to Bacterial Agents in Children less than 5 years<br />

old in Ardebil province and their resistance to antimicrobial agents. Pasture Institute of Iran.<br />

4. 2004-2005: Molecular typing of Shigella spp and E.coli isolated from diarrhea cases and healthy<br />

asymptomatic persons by rRNA gene restriction patterns (ribotyping). Pasture Institute of Iran.<br />

5. 2002-2004: Molecular characterization of Enteropathogenic E.coli isolated from diarrhea and healthy<br />

cases. Pasture Institute of Iran.<br />

6. 1998-1999: Molecular epidemiology of Salmonella enteritidis serotype typhi. Pasture Institute of<br />

Iran.<br />

7. 1995-1998: Preparation and purification of steroptolysin O from Beta hemolytic streptolysin A.<br />

Pasture Institute of Iran.<br />

8. 1994-1998: Survey on prevalence of gastroenteritis due to Salmonella, Shigella and Enteropathogenic<br />

E.coli in Iran and their resistance to antimicrobial agents. Pasteur Institute of Iran.<br />

2


9. 1992-1993: A study on the prevalence rate of Legionella pneumophila in patients with pneumonia in<br />

Tehran Hospitals. Pasteur Institute of Iran.<br />

10. 1994-1998: Survey on prevalence of gastroenteritis due to Salmonella, Shigella and Enteropathogenic<br />

E.coli in Iran and their resistance to antimicrobial agents. Pasteur Institute of Iran.<br />

11. 1998-1999: Molecular epidemiology of Salmonella enteritidis serotype typhi. Pasture Institute of<br />

Iran.<br />

Supervision of Graduate Students :<br />

1. 2004-2005: Ali Sadegh (Msc Thesis).A study of correlation of Shiga toxin producing E.coli with<br />

hemorrhagic colitis in referring patients to Tehran Hospitals. Sadeghian S, Aslani M.M, Alikhani Y.<br />

Microbiology Dept. Pasture Institute of Iran.<br />

2. 2004-2005: Mohammad Reza Asdi( Msc thesis).Determination and typing of intimin genes in<br />

diarrheagenic Escherichia coli. Jafari A, Bouzari S, Olomi M, Aslani M.M. Molecular Biology Dept.<br />

Pasture Institute of Iran.<br />

3. 2002-2003: (Kherkha Maryam , Msc Thesis). Study of correlation between Enteropathogeni E.coli<br />

serotypes and virulence factors. Aslani M.M, Bouzari s. Jafari A. Microbiology Dept. Pasture Institute<br />

of Iran.<br />

4. 1999-2000: (Bahador Abbas Msc Thesis). A study on the prevalence of Vero toxin-producing E.coli in<br />

cattle of Mazandaran province. Badami N, Aslani M.M. Tehran university o Medical science.<br />

5. 1999-2000: (Seyed hamzeh Hassan Msc Thesis). Determination of Heat-labile and Heat-stable toxins<br />

in 50 strains of Aeromonas hydrophila isolated from Ilam and Mazandaran provinces. Aslani M.M,<br />

Assmar M. Azad university, Lahijan Branch.<br />

3


6. 1999-2000.( Barri Hossien Msc Thesis) A study on the prevalence rate of Vero toxin –producing<br />

E.coli in unpasturized milks of Mazandaran province. Badami N, Aslani M.M. Azad university,<br />

Ghom Branch.<br />

7. 1997-1998. (Valiey Kambiz, MD Thesis).The seroprevalence of listeria<br />

monocytogenes in mothers with aborted children by indirect immunofluoresence technique in East-<br />

Azarbijan. Aslani MM, Farajnia S. Rahimi A. Azad University. Tabriz Branch. Veterinary faculty.<br />

8. 1997-1998: (Pouri Parham, MD thesis) A study on the relation between infertility of women and<br />

infection by Mycoplasma hominis and ureaplasma urealyticum . Aslani MM. Farajnia S. Azad<br />

University Tabriz Branch. Veterinary faculty.<br />

9. 1997-1998: (Zendehdaman Mohammad Reza, MD Thesis). Production and Evaluation of antibody of<br />

streptococci group A and group B co-agglutination method. Aslani MM, Farjnia S, Rahimi A. Azad<br />

University, Tabriz Branch. Veterinary faculty<br />

10. 1997-1998: ( Abdolrahemi R, Msc thesis). Prevalence of Vero toxin-producing Escherichia coli<br />

(VTEC) in a randomly selected population of Mazandaran province. Pourmensour M, Aslani M.M.<br />

Azad University. Lahijan Branch.<br />

11. 1995-1996: (Mr Norkhoda Sadegifar,Msc Thesis), Diagnosis of Helicobacter pylori by culture<br />

Histopathological section and urease test, Institute Pasteur of Iran. Bahermand A,Vaziri M, Aslani<br />

MM<br />

12. 1995-1996:(Youesf Alikhani, MSc Thesis),Rapid identification of Mycobacterium tuberculosis bovis<br />

complex by nested PCR. Bahermand A, Aslani MM. Institute Pasteur of Iran.<br />

13. 1995-1996:(Farzaneh Hossieni, MSc Thesis) Preparation and Purification of Streptolysin O From Beta<br />

hemolytic Streptococci Khatami S, Maleckzadeh P, Aslani MM,Azad university. Thesis<br />

4


Publications:<br />

1. Baghaei K, Shokrzadeh L, Jafari F, Dabiri H, Yamaoka Y, Bolfion M, Zojaji H, Aslani MM, Zali<br />

MR. Determination of Helicobacter pylori virulence by analysis of the cag pathogenicity island<br />

isolated from Iranian patients. Dig Liver Dis. (2009)<br />

2. Jafari F, Garcia-Gil LJ, Salmanzadeh-Ahrabi S, Shokrzadeh L, Aslani MM, Pourhoseingholi MA,<br />

Derakhshan F, Zali MR. Diagnosis and prevalence of enteropathogenic bacteria in children less<br />

than 5 years of age with acute diarrhea in Tehran children's hospitals. J Infect.(2009)Jan;58(1):21-7.<br />

3. Aslani MM, Bouzari S. Characterization of virulence genes of non-O157 Shiga toxin-producing<br />

Escherichia coli isolates from two provinces of Iran. Jpn J Infect Dis. 2009 Jan;62(1):16-9.<br />

4. Aslani M.M, Salmanzadeh-ahrabi S, Alikhani MY, Jafari F, Zali MR and Mani ,M. Molecular<br />

detection and antimicrobial resistance of diarrheagenic Escherichia coli strains isolated from<br />

diarrheal cases. Saudi Med J .; Vol 29(3) : 388-392 ., (2008)<br />

5. Salmanzadeh-ahrabi S, Jafari F, Habibi E, Irajian GR, Aslani M.M, Baghbani-Arani F, Zali MR.<br />

Seroypes distribution and antimicrobial resistance rates of Shigella Spp isolates in Tehran, Iran.<br />

Mikrobiyol Bul.; Jul; 41(3): 453-7., (2007)<br />

6. Asadi-karam M, Aslani M.M, Habibi M, Oloomi M. A comparative Evolution study of eae Genes<br />

of the LEE loci in E.coli Strains in Iran with Different countries. Daneshvar ( Scientific –research<br />

Journal of Shahed university, 69 :17-23, (2007)<br />

5


7. Ghaemi E, Aslani M.M, Moradi A V, Dadgar T, Livani S, Mansourian Azad R, Nosrat S B,<br />

Ahmadi A .<br />

Epidemiology of Shigella-associated diarrhea in Gorgan, north of Iran. Saudi J<br />

Gastroenterol. :13:129-132., (2007)<br />

8. Alikhani MY, Mirsalehian A, Fatollahzadeh B, Pourshafie MR, Aslani M.M. Prevalence of<br />

enteropathogenic and shiga toxin-producing Escherichia coli among children with and without<br />

diarrhoea in Iran. J Health Popul Nutr. Mar;25(1):88-93. (2007)<br />

9. Alikhani M.Y, Mirsalehian A and Aslani M.M, HeLa-Cell Adherence Patterns of<br />

Enteropathogenic Escherichia coli (EPEC) Strains Isolated from Faecal Samples .Pakistan J.bio<br />

Sci.9(8).1465-69.,(2006)<br />

10. Sadeghifar N, Aslani M.M., Ghasemi A. Comparison of different laboratory methods for<br />

diagnosis of Helicobacter pylori. Pakistan J bio Sci. 6(6).1146-1149.(2006)<br />

11. Alikhani M.Y, Mirsalehian A and Aslani M.M., Detection of typical and atypical<br />

enteropathogenic Escherichia coli (EPEC) in Iranian children with and without Diarrhea. J Med<br />

Microbio.55:1159-1163., (2006)<br />

12. Ranjbar R, Soltan dallal MM, pourshafie MR, Aslani M.M, Majdzadeh R, Khorramizadeh MR.<br />

Serogroup Distribution of Shigella of in Tehran. Iranian Journal public Health. 33(3):32-35.(2004)<br />

13. Vahdani p, Saifi M, Aslani M.M, Asarian AA, Sharafi K.A . Antibiotics Resistance patterns in<br />

MRSA Isolates from patients admitted in ICU and infectious Ward Tanaffos .3(11), 34-44, (2004)<br />

6


14. Aslani,M.M, Syed hamzeh.H. Characterization and Distribution of Virulence factors in<br />

Aeromonas hydrophila strains isolated from fecal samples of diarrheal and Asymptomatic Healthy<br />

persons, in Ilam, Iran. Iranian Biomedical Journal 8(4):199-203. (2004)<br />

15. Aslani,M.M., Alikhani M.Y .The Role of Aeromonas hydrophila in Diarrhea. Iranian Journal<br />

public Health. 33(3):54-9.(2004)<br />

16. Aslani,M.M., and S.Bouzari. An epidemiological study on Verotoxin-producing Escherichia coli<br />

(VTEC) infection among population of northern region of Iran (Mazandaran and Golestan<br />

provinces). EJEP. 04:345-349, (2003)<br />

17. Katami Sh, Aslani M.M, Pourfallah F. One step purification of sterptolysin O from Streptococci<br />

beta-hemolytic group A (Richard Strains). Journal of Shahid Sadoughi university of Medical<br />

Sciences & Health services (Farsi).10 (4):62-68. (2003)<br />

18. Sadeghifard NK, Aslani M.M ,Azizi Jaliliane F, Shikhiane A. Isolation ,Verotoxin assay and<br />

serogrouping of enterohemorrhagic E.oli (EHEC) strains in Ilam province (Autumn ,1999). Journal<br />

9of Shahid Sadoughi university of Medical Sciences & Health services (Farsi).10 (1):54-59.(2002)<br />

19. Alikhani y, Bahermand A, Zeinali S, Aslani M.M .Clinical trials of PCR for diagnosis of M<br />

.tuberculosis in sterile body fluid. Iranian J infect Dis Trop Med. 7:(18):51-53.(2002)<br />

7


20. Katami Sh, Zamani Z , Hosseini F, Aslani M.M. Comparison of 11 selective media for<br />

sterptolysin O production by group A beta-hemolytic Streptococci (Richard Strains). Hakim<br />

research Journal ( Farsi). 4 (3).193-200. (2001)<br />

21. Aslani. M.M., N Badami. The role of cycloheximide in increasing the sensivity of vero cell to<br />

cytotoxin of verocytotoxin producing Escherichia coli.Yakheth (the cell).2.6:85-89.Summer (2000)<br />

22. Aslani. M.M., N.Badami , and S. Bouzari. Adherence patterns of Verotoxigenic Escherichia coli<br />

(VTEC) non-O157 strains isolated from fecal samples in Iran. Iranian Biomedical Journal 3(3&<br />

4):71-75, (1999)<br />

23. Aslani. M.M., N.Badami, M.Mahmoodi and S.Bouzari. Verotoxigenic-producing Escherichia coli<br />

(VTEC) infection in randomly selected population of Ilam Province (Iran ). Scand J Infect Dis.<br />

30:473-476, (1998)<br />

24. Pourshafie , M.Saifi , M.A. Vahdani. A.Shafie, Aslani. M.M., An outbreak of food–borne<br />

botulism associated with contaminated locally-made cheese in Iran, Scand J Infect Dis. 30:92-<br />

94,(1998)<br />

25. Badami, N. M. Marefatpoor., M.Mohammadi., Aslani M.M, Increase of resistance to Penicillin<br />

and Gentamycin of Enterococci isolated from urine and stool of Tehran hospitalized patients.<br />

Iranian J infect Dis Trop Med. 2:(5):38-43.(1998)<br />

8


26. Shirvani F, Momenzadh A, Aslani M.M ,Torabi J ,Khaleghi R, Sharokhi N. Prevalence of vaginal<br />

colonization of group B Streptococcus in Tehran’s women and its relationship to colonization in<br />

newborns. Pejouhandeh .(farsi).2(4).(1998)<br />

27. Aslani M.M. M.Pourmansour, M.Motavalian Isolation of Legionella pneumophila from Tehran<br />

Hospital water samples. Iranian Biomedical Journal 1(1):65-67,(1997)<br />

28. Sadegifar N,M. Vaziri Khashani, A.R. Bahremand. M.M.Aslani. Comparison of culture and rapid<br />

Urease test in diagnosis of Helicobacter pylori. Scientific J Ilam University Med Sci. 14:15-<br />

19,(1997)<br />

29. Aslani, M.M. R, Ghargozlo. Rapid identification of Group A Streptococci by L-pyrolidonyl-bnaphtylamide<br />

Hydrolysis. MJIRI, Vol.9, No3, 243-245, (1995)<br />

Books:<br />

1. Aslani M.M, Aslani Hamid Reza. Genetics in medicine , First , Second & Third Edition<br />

,Daneshpajo Medical Publication. Tehran ,Iran, 1368(1989) Farsi.(Translated from English: Genetics<br />

in on Medicine , Thompson & Thompson forth Edition)<br />

2. Aslani M.M, Akbarzadeh A , Genetics in medicine , First Edition , Noor-e - Danesh Medical<br />

Publication. Tehran ,Iran,1381(2002) Farsi. ( Translated from English: Genetics in on Medicine ,<br />

Thompson & Thompson Sixth Edition)<br />

3. Aslani M.M, Staining methods in microbiology First Edition ,Noor-e -Danesh Medical Publication.<br />

Tehran ,Iran , 1383( 2004) Farsi<br />

9


Congress :<br />

1. Aslani,M.M , Shoraj F,Rehisi. Presence of virulence genes and antimicrobial resistance in shiga<br />

toxin producing E.coli (STEC) and Enteropathogenic E.coli(EPEC). World conference on magic<br />

bullets .Celebrating Paul Ehrich’s 150 rd brith day, Nurnberg , Germany, Sep ,(2005)<br />

2. Aslani,M.M , Syedhamzeh. H, Shoraj F PCR detection and distribution of virulence genes in<br />

Aeromonas hydrophila isolated Iran. 6 rd<br />

International Meeting on Microbial Epidemiological<br />

Markers ,Switzerland ,Aug , (2003)<br />

3. Aslani,M.M, Shoraj F Syedhamzeh. H, Determination virulence factors of Aeromonas<br />

hydrophila isolated from Mazndran and Ilam provinces (Iran). 5 rd microbiology congress, Ahwas ,<br />

Iran, Jan , (2003)<br />

4. Alikhani MY, Bahremand AR, Aslani,M.M, Norkhoda Sadegifar. Evaluation of Mycobacterum<br />

tuberculosis DNA Extraction methods in clinical specimens and Mycobacteria safe for PCR . 4 th<br />

microbiology congress, Tehran, Iran, Nov, (2001)<br />

5. Bahador A, Barri H, N.Badami Aslani, M.M, Prevalence of Verotoxin producing E.coli in milks<br />

of Golestan’S Cows. 4 th microbiology congress, Tehran, Iran, Nov,(2001)<br />

6. Aslani,M.M, Norkhoda Sadegifar. Isolation of Verotoxin producing E.coli at Ilam province<br />

(autumn 1998). 4 th microbiology congress, Tehran, Iran, Nov,(2001)<br />

7. Aslani, M.M, N.Badami, and S.Bouzari. An Epidemiological study on Shiga toxin producing<br />

Escherichia coli (STEC) infection among population of northern region of Iran (Mazandaran and<br />

Golestan provinces) .10 th<br />

international congress of Bacteriology and applied microbiology. Paris<br />

July( 2002)<br />

10


8. Aslani, M.M, N.Badami, and S.Bouzari. Adherence patterns of Verotoxigenic Escherichia coli<br />

(VTEC) non-O157 strains isolated from fecal samples in Iran. 3 rd<br />

microbiology congress,<br />

Hamedan, Iran, Aug (2000)<br />

9. Bahador A,N.Badami, and Aslani, M.M. Prevalence of Verotoxigenic Escherichia coli (VTEC) in<br />

cattle of Mazandaran province (Iran). 3 rd microbiology congress, Hamedan, Iran,Aug, (2000)<br />

10. Syedhamzeh. H, Aslani,M.M. Enterotoxin production among Aeromonas hydrophila isolated from<br />

Mazndran and Ilam provinces (Iran). 3 rd microbiology congress,Hamedan , Iran, Aug, (2000)<br />

11. Aslani, M.M, N.Badami, M.Mahmoodi, s.Bouzari, F.Shoraj, E.Shafie. Verotoxigenic-producing<br />

Escherichia coli (VTEC) infection in rural and urban areas of Ilam Province. 4 th national congress<br />

of zoo noses in Iran , Tehran, April (2000)<br />

12. Alikhani M.Y., A.R.Bahrmand , S.Zienali., Aslani, M.M, Inhibitors in polymerase chain reaction.<br />

14 th Nationwide congress on tuberculosis. Kashan , Iran , Oct ,(1998)<br />

13. Alikhani M.Y., A.R.Bahrmand, S.Zienali., Aslani, M.M, Rapid identification of Mycobacterium<br />

tuberculosis menigitidis by PCR. 7 th Iranian congress on infectious disease and tropical medicine ,<br />

Babolsar , Iran , Oct , (1998)<br />

14. -Aslani M.M, Opportunistic Bacterial Infection in immune–deficient patients, Tabriz university of<br />

medical sciences (Iran),The Third Iranian Congress of biochemistry & Laboratory Sciences.Oct,<br />

(1995)<br />

15. Malkov I.G., Bahrmand A.R., Saifi M., Aslani M.M., Ardekani A.M. The PCR indentification and<br />

differentiation of M.tuberculosis –bovis complex from atypical mycobacterium strains. Abst. 28 th<br />

World Conference of international Union Against Tuberculosis and Lung Disease.<br />

(Germany).(1994)<br />

11


16. Aslani, M.M. R, Ghargozlo. Rapid Identification of Group A Streptococci by pyrolidonyl –Bnaphtylamide<br />

Hydrolysis. Mazandaran Medical Sciences University (Iran). First Microbiology<br />

congress Nov., (1992)<br />

17. Aslani M.M. M.Pourmansour , M.Motavalian Isolation of legionella sp from water supply<br />

samples of Tehran hospital , Mazandaran Medical Science University. (Iran). First Microbiology<br />

Congress Nov., (1992)<br />

Test & Techniques:<br />

1. Isolation and Identification of Legionella pneumophila, Microbiology Depatement/Iran/1990<br />

2. PCR Technique for diagnosis of Mycobacterium tuberculosis, Mycobacteriology Department<br />

/Iran/1993<br />

3. Identification of bacteria by sequencing rrs gene (coding for 16s rRNA)/ Unite Biodiversite des<br />

Bacteries Pathogen's Emergentes , Institute Pasteur of Paris , France ,2000-2001<br />

4. Pulsed Field Gel Electrophoresis / Unite Biodiversite des Bacteries Pathogen's Emergentes ,<br />

Institute Pasteur of Paris , France ,2000-2001<br />

5. Molecular Serotyping of E.coli by restriction of amplified flagellin genes and rfb gene cluster/.<br />

Microbiology Department/ Iran/ 2004<br />

6. Ribotyping/ Microbiology Department/Iran/ 2005<br />

Professional membership:<br />

1. Iranian Society for Microbiology, Iran ,Since 1996<br />

2. American society for Microbiology ,USA, Since 1992<br />

12


Position Held:<br />

1. Head Enterobacteriaceae laboratory, since 1995<br />

2. Head of Microbiology Department, from June 2004 to Sep 2005<br />

Professional Experience:<br />

1. PCR Technique for diagnosis of Mycobacterium tuberculosis<br />

2. Isolation and Identification of Legionella pneumophila<br />

3. DNA-fingerprinting by UP-PCR<br />

4. Salmonella , Shigella and Enteropatogenic E.coli<br />

5. Enterotoxigenic E.coli (LT, ST and Verotoxigenic E.coli)<br />

6. Identification of pathogenicity gene of bacteria<br />

7. Molecular Serotyping of E.coli by restriction of amplified flagellin genes and rfb gene cluster.<br />

8. RLFP<br />

9. Ribotyping<br />

10. Identification of bacteria by sequencing rrs gene (coding for 16s rRNA)<br />

11. Pulsed Field Gel Electrophoresis<br />

Language :<br />

English<br />

French<br />

13

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