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Cover and table of contents - British Thoracic Society

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AN INTERNATIONAL JOURNAL OFRESPIRATORY MEDICINEJournal <strong>of</strong> the<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>Editor-in-ChiefJ A Wedzicha (UK)EditorS L Johnston (UK)Associate EditorsJ S Brown (UK)P M A Calverley (UK)M Dusmet (UK)J S Elborn (N Irel<strong>and</strong>)A J Fisher (UK)J M FitzGerald (Canada)J A Fleetham (Canada)N M Foley (UK)I Hall (UK)J R Hurst (UK)R Hubbard (UK)D A Lomas (UK)D M Mannino (USA)F D Martinez (USA)C Robertson (Australia)B Schonh<strong>of</strong>er (Germany)G A Silvestri (USA)G I Town (New Zeal<strong>and</strong>)M K B Whyte (UK)Statistical EditorsJ Gibson (UK)L Tata (UK)Images EditorsJ M FitzGerald (Canada)J R Mayo (Canada)J C Hogg (Canada)Letters EditorJ R Hurst (UK)Lung Alert EditorsA Bhowmik (UK)J Quint (UK)President, <strong>British</strong> <strong>Thoracic</strong><strong>Society</strong>P CorrisProduction EditorJulia DimitriouJournal ManagerClaire FolkesPublisherJulie SolomonGuidelines for Authors <strong>and</strong>ReviewersFull instructions are available onlineat http://thorax.bmj.com/ifora.Articles must be submittedelectronically http://submit-thorax.bmj.com. Authors retain copyrightbut are required to grant Thorax anexclusive licence to publish http://thorax.bmj.com/ifora/licence.dtlImpact Factor: 7.04Aims <strong>and</strong> Scope: Thorax enjoys an enviable<strong>and</strong> longst<strong>and</strong>ing reputation for publishingclinical <strong>and</strong> experimental research articlescovering many disciplines, includingpathology, immunology <strong>and</strong> surgeryInternational Advisory BoardN Ambrosino (Italy)J N Baraniuk (USA)P J Barnes (UK)C R W Beasley (New Zeal<strong>and</strong>)J R Britton (UK)A S Buist (USA)E R Chilvers (UK)S-H Cho (Korea)S-E Dahlen (Sweden)G C Donaldson (UK)M W Elliott (UK)Y Fukuchi (Japan)D M Geddes (UK)P Goldstraw (UK)R Goldstein (Canada)C Griffiths (UK)J C Hogg (Canada)S T Holgate (UK)P Hopewell (USA)M Ichinose (Japan)A Kendrick (UK)T King (USA)A J Knox (UK)C K W Lai (China)G J Laurent (UK)P LeSouef (Australia)W MacNee (UK)C Mayaud (France)J Moore-Gillon (UK)Subscription InformationThorax is published monthly (subscribers receive all supplements)Institutional Rates2010Print£491; US$957; 663OnlineSite licences are priced on FTEbasis <strong>and</strong> allow access by thewhole institution. Print isavailable at deeply discountedrates for online subscribers;details available online at http://group.bmj.com/group/subssales/subscriptionsor contactthe Subscription Manager in theUK (see above right).A Morice (UK)R Panettieri (USA)A Papi (Italy)N G Papadopoulos (Greece)M R Partridge (UK)I D Pavord (UK)M G Pearson (UK)T A E Platts Mills (USA)L Restrick (UK)D S Robinson (UK)R M Rudd (UK)T A R Seemungal (Trinidad & Tobago)S Sethi (USA)T Sethi (UK)A K Simonds (UK)P Sliwinski (Pol<strong>and</strong>)R A Stockley (UK)J K Stoller (USA)M J Tobin (USA)A Torres (Spain)J Vestbo (Denmark)E H Walters (Australia)S T Weiss (USA)A Wells (UK)JW Wilson (Australia)A A Woodcock (UK)M Woodhead (UK)R Zuwallack (USA)Editor, BMJPersonal Rates2010Print (includes online access atno additional cost)£209; US$408; 282Online only£115; US$224; 155ISSN 0040-6376 (print)ISSN 1468-3296 (online)Personal print or online only <strong>and</strong> institutional print subscriptions may bepurchased online at http://group.bmj.com/group/subs-sales/subscriptions(payment by (MasterCard/Visa only).Residents <strong>of</strong> some EC countries must pay VAT; for details call us or visithttp://group.bmj.com/group/subs-sales/subscriptions/subs-vatContact DetailsEditorial OfficeBMJ Publishing Group Ltd, BMA House, TavistockSquare London, WC1H 9JR, UKT: +44 (0)20 7383 6168F: +44 (0)20 7383 6668E: thorax@bmjgroup.comPermissionsSee http://journals.bmj.com/misc/permissions.dtlSupplement EnquiriesT: +44 (0)20 7383 6057F: +44 (0)20 7554 6795E: cfolkes@bmjgroup.comFor ALL subscription enquiries <strong>and</strong> ordersT: +44 (0)20 7383 6270F: +44 (0)20 7383 6402E: support@bmjgroup.comhttp://group.bmj.com/group/customerservice/journalhelp/journalhelpAdvertisingT: +44 (0)20 7383 6386F: +44 (0)20 7383 6556E: ngray@bmjgroup.comhttp://group.bmj.com/group/advertisingAuthor ReprintsReprints AdministratorT: +44 (0)20 7383 6305F: +44 (0)207 554 6185E: admin.reprints@bmjgroup.comCommercial Reprints (except USA & Canada)Nadia Gurney-R<strong>and</strong>allT: +44 (0)20 8445 5825M: +44 (0)7866 262344F: +44 (0)20 8445 5870E: ngurneyr<strong>and</strong>all@bmjgroup.comCommercial Reprints (USA & Canada)Marsha FoglerT: +1 800 482 1450 (toll free in the USA)T: +1 856 489 4446 (outside the USA)F: +1 856 489 4449E: mfogler@medicalreprints.com<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>17 Doughty StreetLondon WC1N 2PL, UKT: +44 (0)20 7831 8778F: +44 (0)20 7831 8766E: bts@brit-thoracic.org.ukhttp://www.brit-thoracic.org.uk/index.html


BTS Pleural Disease Guideline 2010<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>Pleural Disease Guideline Group:a sub-group <strong>of</strong> the <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>St<strong>and</strong>ards <strong>of</strong> Care Committee


The BTS Pleural Disease Guideline is endorsed by:Royal College <strong>of</strong> Physicians, LondonRoyal College <strong>of</strong> Surgeons <strong>of</strong> Engl<strong>and</strong>Royal College <strong>of</strong> Physicians <strong>of</strong> EdinburghRoyal College <strong>of</strong> Surgeons <strong>of</strong> EdinburghRoyal College <strong>of</strong> Physicians <strong>and</strong> Surgeons <strong>of</strong> GlasgowRoyal College <strong>of</strong> RadiologistsRoyal College <strong>of</strong> AnaesthetistsRoyal College <strong>of</strong> PathologistsCollege <strong>of</strong> Emergency Medicine<strong>Society</strong> for Acute MedicineAssociation for Clinical Biochemistry<strong>British</strong> <strong>Society</strong> <strong>of</strong> Clinical Cytology


Contents Volume 65 Suppl II | THORAX August 2010BTS Pleural Disease Guideline 2010Journal <strong>of</strong> the <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>Impact Factor: 7.04Editor-in-ChiefJ A Wedzicha (UK)EditorS L Johnston (UK)Associate EditorsJ S Brown (UK) J R Hurst (UK)P M A Calverley (UK) D A Lomas (UK)M Dusmet (UK) D M Mannino (USA)J S Elborn (N Irel<strong>and</strong>) F D Martinez (USA)A J Fisher (UK) C Robertson (Australia)J M FitzGerald (Canada) B Schonh<strong>of</strong>er (Germany)J A Fleetham (Canada) G A Silvestri (USA)N M Foley (UK) G I Town (New Zeal<strong>and</strong>)I Hall (UK)M K B Whyte (UK)R Hubbard (UK)Statistical EditorsL Tata (UK)J Gibson (UK)Images EditorsJ M FitzGerald (Canada)J R Mayo (Canada)J C Hogg (Canada)Letters EditorJ R Hurst (UK)Lung Alert EditorsA Bhowmik (UK)J Quint (UK)President, <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>P CorrisEditorial OfficeBMJ Publishing Group Ltd, BMA House,Tavistock Square, London WC1H 9JR, UKT: +44 (0)20 7383 6147F: +44 (0)20 7383 6668E: thorax@bmjgroup.comISSN: 0040-6376 (print)ISSN: 1468-3296 (online)ii1ii4ii18ii32Introduction <strong>and</strong> methods: <strong>British</strong> <strong>Thoracic</strong><strong>Society</strong> pleural disease guideline 2010I Du R<strong>and</strong>, N MaskellInvestigation <strong>of</strong> a unilateral pleural effusion inadults: <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010C Hooper, Y C G Lee, N Maskell, on behalf <strong>of</strong> theBTS Pleural Guideline GroupManagement <strong>of</strong> spontaneous pneumothorax:<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010A MacDuff, A Arnold, J Harvey, on behalf <strong>of</strong> theBTS Pleural Disease Guideline GroupManagement <strong>of</strong> a malignant pleural effusion:<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010M E Roberts, E Neville, R G Berrisford,G Antunes, N J Ali, on behalf <strong>of</strong> the BTS PleuralDisease Guideline GroupOnline supporting documentation is available atwww.brit-thoracic.org.ukii41ii54ii61Management <strong>of</strong> pleural infection in adults:<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010H E Davies, R J O Davies, C W H Davies,on behalf <strong>of</strong> the BTS Pleural Disease GuidelineGroupLocal anaesthetic thoracoscopy:<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010N M Rahman, N J Ali, G Brown, S J Chapman,R J O Davies, N J Downer, F V Gleeson,T Q Howes, T Treasure, S Singh, G D Phillips,on behalf <strong>of</strong> the <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> PleuralDisease Guideline GroupPleural procedures <strong>and</strong> thoracic ultrasound:<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> pleural diseaseguideline 2010T Havelock, R Teoh, D Laws, F Gleeson, on behalf<strong>of</strong> the BTS Pleural Disease Guideline GroupDisclaimer: Thorax is owned <strong>and</strong> published by the<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> <strong>and</strong> BMJ Publishing GroupLtd, a wholly owned subsidiary <strong>of</strong> the <strong>British</strong> MedicalAssociation. The owners grant editorial freedom tothe Editor <strong>of</strong> Thorax.Thorax follows guidelines on editorialindependence produced by the World Association<strong>of</strong> Medical Editors <strong>and</strong> the code on goodpublication practice <strong>of</strong> the Committee onPublication Ethics.Thorax is intended for medical pr<strong>of</strong>essionals <strong>and</strong> isprovided without warranty, express or implied.Statements in the Journal are there sponsibility <strong>of</strong>their authors <strong>and</strong> advertisers <strong>and</strong> not authors’institutions, the BMJ Publishing Group Ltd, the<strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong> or the BMA unless otherwisespecified or determined by law. Acceptance <strong>of</strong>advertising does not imply endorsement.To the fullest extent permitted by law, the BMJPublishing Group Ltd shall not be liable for any loss,injury or damage resulting from the use <strong>of</strong> Thoraxor any information in it whether based on contract,tort or otherwise. Readers are advised to verify anyinformation they choose to rely on.Copyright: Ó 2010 BMJ Publishing Group Ltd <strong>and</strong>the <strong>British</strong> <strong>Thoracic</strong> <strong>Society</strong>. All rights reserved; nopart <strong>of</strong> this publication may be reproduced, stored ina retrieval system or transmitted in any form or byany means, electronic, mechanical, photocopying,recording or otherwise without the prior permission<strong>of</strong> Thorax.Thorax is published by BMJ Publishing Group Ltd,typeset by TNQ Books & Journals, Chennai, India<strong>and</strong> printed in the UK on acid-free paper by BuxtonPress, Buxton, UK.Thorax (ISSN No: 0040–6376) is publishedmonthly by BMJ Publishing Group <strong>and</strong> distributedin the USA by Mercury International Ltd.Periodicals postage paid at Rahway, NJ.POSTMASTER: send address changes to Thorax,Mercury International Ltd, 365 Blair Road, Avenel,NJ, 07001, USA.

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