Pathology of Head and Neck Malignancies - Aroi.org

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• Genetic susceptibility:HLA-A2, B17, Bw46, BW58• EBV 75-100%Salted fish, poor hygiene,smoke, tobacco, chemicalfumes, harbal medicineA. Keratinizing: WD, MD,PD25% <strong>of</strong> all NPCrare under 40 yrs <strong>of</strong> ageB. Non-keratinizing– Differentiated– Undifferentiated
• Non-keratinizing– differentiated 12%– Undifferentiated type60%• D/D: NHL• Treat: RT• Prog: clinical stage, sex,age, genetic factor
Page 3 and 4: Tumors of the upper respiratory tra
Page 5 and 6: Malignant epithelial and neuroectod
Page 7 and 8: Squamous cell carcinoma ofsinonasal
Page 9 and 10: • Secondary malignancyeither at a
Page 11 and 12: Verrucous carcinoma• WD locally d
Page 13 and 14: Basaloid Squamous cell carcinoma•
Page 15: Nasopharyngeal Carcinoma• Age ran
Page 19 and 20: Olfactory neuroblastoma• Upper1/3
Page 21 and 22: CGNFSynS100
Page 23 and 24: Treat: complete surgical eradicatio
Page 25 and 26: Mucosal malignant melanoma• 0.5-3
Page 27 and 28: EM: melanosome &premelanosome• Ag
Page 29 and 30: • Intestinal/colonic types:papill
Page 31 and 32: Non-epithelial malignant neoplasm
Page 33 and 34: Extramedullary plasmacytoma• 3-5%
Page 36 and 37: • With surgical excision 5-yr sur
Page 38 and 39: Osteosarcoma• 10% of OS occur in
Page 40 and 41: Chondrosarcoma• 5-12%• 4 th -7
Page 42 and 43: Tumors of oral cavity• Squamous c
Page 44 and 45: ME carcinoma• Most common maligtu
Page 46 and 47: Adenoid cystic carcinoma• 4 Th -6
Page 48 and 49: Thyroid and parathyroid malignancie
Page 50 and 51: Follicular carcinoma• Uncommon•
Page 52 and 53: Anaplastic carcinoma of thyroid•
Page 54 and 55: Orbital malignancies• Basal cell

Pathology of Head and Neck Malignancies - Aroi.org

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