Introduction to Arvs - Botswana Teen Club
Introduction to Arvs - Botswana Teen Club
Introduction to Arvs - Botswana Teen Club
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With ARVs, People With HIV Can Live<br />
Long, Healthy Lives<br />
The child on ARVs<br />
can have a<br />
normal, healthy<br />
life<br />
How should ARVs be taken?<br />
� The patient must take three different ARV<br />
drugs. The medicines do not work well if<br />
you take only one or two.<br />
� ARVs usually work in combination because<br />
of the nature of the replication cycle of the<br />
HIV.<br />
� If the ARV that operates at a particular site<br />
of the CD4 cell fail <strong>to</strong> s<strong>to</strong>p some of the<br />
virus, the other ARVs in the combination<br />
will operate at the other sites <strong>to</strong> make the<br />
virus inactive.<br />
� Another way <strong>to</strong><br />
explain the<br />
importance of taking<br />
all three ARVs is <strong>to</strong><br />
compare the ARVs <strong>to</strong><br />
the three legs of a<br />
cooking pot.<br />
� If a pot is balancing<br />
on three s<strong>to</strong>nes and<br />
you take one away,<br />
the pot will spill.<br />
What do ARVS do?<br />
� They keep the virus<br />
from multiplying<br />
� A good way <strong>to</strong> think<br />
about how ARVs<br />
work is that they<br />
keep the virus<br />
“sleeping”<br />
How <strong>to</strong> educate caregivers and children on<br />
taking all the three drugs!<br />
Look at the soldier in the<br />
picture.<br />
He is wearing three things:<br />
a hat, a shirt and pants<br />
You can tell young patients<br />
that ARVs are like the<br />
soldier’s hat, shirt and<br />
pants. If the soldier lost his<br />
pants, it would be harder<br />
for him <strong>to</strong> work!<br />
How should ARVs be taken?<br />
HAART refers <strong>to</strong> taking three effective<br />
antiretroviral medicines <strong>to</strong>gether<br />
The classes of ARV drugs are:<br />
� Nucleoside Reverse Transcriptase<br />
Inhibi<strong>to</strong>rs (NRTIs),<br />
� Non-Nucleoside Reverse<br />
Transcriptase Inhibi<strong>to</strong>rs (NNRTIs)<br />
� Protease Inhibi<strong>to</strong>rs (PIs).<br />
� Fusion Inhibi<strong>to</strong>rs<br />
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