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Introduction to Arvs - Botswana Teen Club

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With ARVs, People With HIV Can Live<br />

Long, Healthy Lives<br />

The child on ARVs<br />

can have a<br />

normal, healthy<br />

life<br />

How should ARVs be taken?<br />

� The patient must take three different ARV<br />

drugs. The medicines do not work well if<br />

you take only one or two.<br />

� ARVs usually work in combination because<br />

of the nature of the replication cycle of the<br />

HIV.<br />

� If the ARV that operates at a particular site<br />

of the CD4 cell fail <strong>to</strong> s<strong>to</strong>p some of the<br />

virus, the other ARVs in the combination<br />

will operate at the other sites <strong>to</strong> make the<br />

virus inactive.<br />

� Another way <strong>to</strong><br />

explain the<br />

importance of taking<br />

all three ARVs is <strong>to</strong><br />

compare the ARVs <strong>to</strong><br />

the three legs of a<br />

cooking pot.<br />

� If a pot is balancing<br />

on three s<strong>to</strong>nes and<br />

you take one away,<br />

the pot will spill.<br />

What do ARVS do?<br />

� They keep the virus<br />

from multiplying<br />

� A good way <strong>to</strong> think<br />

about how ARVs<br />

work is that they<br />

keep the virus<br />

“sleeping”<br />

How <strong>to</strong> educate caregivers and children on<br />

taking all the three drugs!<br />

Look at the soldier in the<br />

picture.<br />

He is wearing three things:<br />

a hat, a shirt and pants<br />

You can tell young patients<br />

that ARVs are like the<br />

soldier’s hat, shirt and<br />

pants. If the soldier lost his<br />

pants, it would be harder<br />

for him <strong>to</strong> work!<br />

How should ARVs be taken?<br />

HAART refers <strong>to</strong> taking three effective<br />

antiretroviral medicines <strong>to</strong>gether<br />

The classes of ARV drugs are:<br />

� Nucleoside Reverse Transcriptase<br />

Inhibi<strong>to</strong>rs (NRTIs),<br />

� Non-Nucleoside Reverse<br />

Transcriptase Inhibi<strong>to</strong>rs (NNRTIs)<br />

� Protease Inhibi<strong>to</strong>rs (PIs).<br />

� Fusion Inhibi<strong>to</strong>rs<br />

2

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