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Perception • Active process • Involves selection, organization and ...

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Why the high responsiveness to expectationof pain relief?<strong>•</strong> Evidence that expectation of pain relief activatesmu-opioid neurotransmitter system (“endorphins”)Red & orangeindicate regions ofheightened muopioidactivitywhen P reportspositive effect ofplaceboZubieta et al - Placebo Effects Mediated by Endogenous Opioid Activity on µ-Opioid Receptors (2005)

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