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3. Proposal for an integrated life science SR ... - EMBL Hamburg

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<strong>3.</strong>2.2. <strong>Proposal</strong><br />

28<br />

<strong>Proposal</strong> by <strong>EMBL</strong>-<strong>Hamburg</strong><br />

<strong>for</strong> <strong>an</strong> Integrated Life Science Centre at PETRA-III<br />

The proposed BioSAXS beamline will be built in the framework of the general <strong>EMBL</strong> concept<br />

of <strong>life</strong> <strong>science</strong> applications at PETRA-III. The modular design of the proposed BioSAXS<br />

beamline will facilitate the straight<strong>for</strong>ward switching between different modes of operation<br />

(Figure 5):<br />

C<strong>an</strong>ted* 1<br />

undulator<br />

Primary Slit<br />

System with<br />

white beam<br />

monitor<br />

Fixed exit* 2<br />

Si (111)<br />

double monochromator<br />

Optional :<br />

Multilayer<br />

monochromator<br />

Slit System<br />

with beam<br />

monitor<br />

KB focusing<br />

mirror system* 3 * 4<br />

Beam<br />

monitor<br />

* 1 X-ray beam originating from 2 nd undulator is separated by 5 mrad<br />

*2 Offset is 30 mm.<br />

*3 Option <strong>for</strong> pink beam: N2 cooled vertically focusing mirror<br />

* 4 Option <strong>for</strong> supplementary X-ray refractive lenses<br />

Figure 5: Schematic design of the SAXS beamline <strong>for</strong> biological applications.<br />

• High-precision scattering experiments using the high energy resolution of a double<br />

crystal monochromator system, with its ability to tune the energy in a large energy r<strong>an</strong>ge<br />

from 4 to 20 keV (Δλ/λ = 1 x 10 -4 <strong>an</strong>d 2 x 10 13 ph/s at 8 keV);<br />

• Increased flux with a lower energy resolution of a multi-layer monochromator system <strong>for</strong><br />

fast kinetic experiments (Δλ/λ=1 x 10 -2 <strong>an</strong>d 3 x 10 15 ph/s at 8 keV);<br />

Slit<br />

Systems<br />

with beam<br />

monitors<br />

WAXS/SAXS<br />

detectors (in<br />

focus) with<br />

beam monitor<br />

Sample<br />

Front end Optical hutch<br />

Experimental<br />

hutch

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