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Attachment A –Biographical Sketches of the PanelistsDr. Penny Fenner-CrispDr. Fenner-Crisp served as the ExecutiveDirector of the ILSI Risk Science Institute (RSI)from December 2000 until August 2004,following a 22-year career at US EPA. Herduties at EPA included nearly 12 years servingin several capacities as the Senior ScienceAdvisor, Deputy Director and Director of theHealth Effects Division of the Office of PesticidePrograms. Earlier assignments included servingas the Director of the Health and EnvironmentalReview Division (HERD) of the Office ofPollution Prevention and Toxics (OPPT) andSenior Toxicologist in the Health Effects Branchof the Office of Drinking Water (ODW). Sheplayed key roles in the development of manyEPA risk assessment policies and practicesprimarily related to human health and wasinvolved in the activities of several internationalorganizations as an expert on several WHOIPCS working groups, as a member of the WHOExpert Panel of the Joint Meeting on PesticideResidues for nine years and as the lead U.S.Delegate to several workgroups of the OECDtest guidelines program. In April, 2000, s<strong>here</strong>ceived the Agency’s highest award, theFitzhugh Green Award, for her contributions onbehalf of EPA to its international activities.Dr. Fenner-Crisp received her Ph.D. inPharmacology from the University of TexasMedical Branch in Galveston and is a memberand former officer of several professionalscientific societies including of the Society ofToxicology and the Society for Risk Analysis.She has been a Diplomate of the AmericanBoard of Toxicology since 1984 and served onits Board of Directors from 2001-2005. Sheserved on EPA’s Endocrine Disruptor MethodsValidation Subcommittee from 2001-2004 andthe Strategic Science Team of the AmericanChemistry Council’s Long-range ResearchInitiative from 2002-2005. Currently, she is amember of the Board of Directors of theMidwest Center for Environmental Science andPublic Policy, the Drinking Water Committee ofEPA’s Science Advisory Board and EPA’s NationalPollution Prevention and Toxics AdvisoryCommittee. She also is a member of theNational Academies of Sciences expert groupcharged with conducting a review of the Workerand Public Health Activities Programadministered by the Department of Energy andthe Department of Health and HumanServices.Dr. Carl L. KeenDr. Carl L. Keen is the Mars Chair inDevelopmental Nutrition, Professor of Nutrition& Internal Medicine, and a Nutritionist in theAgricultural Experiment Station at the Universityof California at Davis. Dr. Keen received hisB.S. and Ph.D. degrees in Nutrition from theUniversity of California, Davis. Dr. Keen´sresearch group has four main areas of focus.The first concerns the influence of diet onembryonic and fetal development. A significantproportion of birth defects are the consequenceof embryonic and fetal malnutrition. A thesis inthe laboratory is that the correction of suboptimalnutritional deficiencies during earlydevelopment should result in a markedreduction in pregnancy complications. Thesecond research theme in the group is the studyof gene-nutrient interactions, with an emphasison how subtle changes in cell nutrientconcentrations can influence the expression ofselect genes. The third major research theme inthe group is the study of how diet influencesoxidant defense systems and cellular oxidativedamage. The fourth area of research in thelaboratory is on the effects of diet on thedevelopment and progression of vasculardisease. A current hypothesis in the laboratoryis that the putative cardiovascular healthbenefits associated with plant food-rich dietscan be attributed in part to their flavanolcontent. Dr. Keen’s group has over 600 peerreviewedscientific papers in the above areas.15

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