The pathology of malaria

More documents

Recommendations

Info

Cerebral malaria• Stasis leads to anaerobic glycolysis with lacticacidosis• The cause of the coma is unknown• Cerebral oedema is no longer considered tobe the cause in most cases• Age , geographical location & genotype• Rare cases of intra cranial haemorrage arereported (at least one case of subdural haem.in a young man (21 years old) with severemalaria
Cerebral Malaria• Possible pathogenesis includes:-Vascular causes-Mechanical causes-Metabolic causes(ICAM,CD36,PfEMP1)-Immunopathological causes-Breakdown of blood brain barrier-TNF,IL1,IL6 & IL8(Lack of IL10)
Page 1 and 2: ProfessorAhmed A.Mohamedani
Page 4 and 5: Introduction• The pigment is then
Page 6 and 7: Changes in the RBCS• The parasite
Page 8 and 9: Sequestration• Caused by P. falci
Page 10 and 11: Several Parasite Proteins Are Assoc
Page 12 and 13: Sequestrationand cytoadherenceSourc
Page 14 and 15: Prolonged shock
Page 16 and 17: Hyperparasitesaemia
Page 18 and 19: WHO definitions for severe malaria
Page 20 and 21: Pathogenesis of Falciparum malaria
Page 22: Cerebral malaria• Occurs with fal
Page 27 and 28: Malaria & Blood Changes-Anaemia•
Page 29 and 30: Severe anemiaSource: Essential mala
Page 31 and 32: Malaria & Blood Changes• Coagulat
Page 33 and 34: Black Water Fever• It is more com
Page 35 and 36: Black Water Fever• Therefore the
Page 38 and 39: Some Biochemical Derangements• Hy
Page 40: The liver in malaria• Enlarged &
Page 43 and 44: The Spleen in Malaria• Enlarges ,
Page 45 and 46: scarringcryoglobulinemia25°C 4°Cw
Page 47 and 48: The Kidneys & Quartan Malaria• Qu
Page 49 and 50: The lungs & MalariaCauses pulmonary
Page 51 and 52: Adrenals ,GIT, Pancreas & Heart in
Page 53 and 54: Who:Laboratory indicators of poor p
Page 55 and 56: 4. A. A. Mohamedani, O. Khalafalla
Page 57 and 58: 8. BAKRI Y. M. NOUR*,MD, PÈTRA F.

The pathology of malaria

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?