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Vol.25 Num(6) - Program in Neuroscience, University of Toronto

Vol.25 Num(6) - Program in Neuroscience, University of Toronto

Vol.25 Num(6) - Program in Neuroscience, University of Toronto

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<strong>University</strong> <strong>of</strong> <strong>Toronto</strong> <strong>Neuroscience</strong> <strong>Program</strong>NEUROSCIENCENEWSLETTERPROGRAM NEWSNEWS FROM THE PIN OFFICE:Dear PIN members:Due to the creation <strong>of</strong> UTNP and the result<strong>in</strong>g reorganization here, Iwill be leav<strong>in</strong>g my position <strong>in</strong> the <strong>Program</strong> as <strong>of</strong> February 12, 2009.Over the past 10 years, I have enjoyed work<strong>in</strong>g with everyone verymuch and I send my best wishes for your future successes. As <strong>of</strong>February 12 th , please send all <strong>of</strong> your correspondence top.neuroscience@utoronto.ca and not to pat.reed@utoronto.ca.Thank you,Pat ReedNEW PIN STUDENTS:We would like to welcome the follow<strong>in</strong>g students to the <strong>Neuroscience</strong><strong>Program</strong>:Student’s Name Degree Supervisor DepartmentMatthew Dub<strong>in</strong>s PhD Laura-Ann PetittoDaniel Lee MA Adam AndersonPsychologyPsychologyEsther Lee MSc John Yeomans CSBIska Moxon-Emre MSc Lyanne Schlichter PhysiologyRyan Salewski PhD Michael Fehl<strong>in</strong>gs IMSNatalya Shulyakova PhD L<strong>in</strong>da Mills PhysiologyGRADUATING STUDENTS:We would like to congratulate the follow<strong>in</strong>g PIN graduates:Student’s Name Degree Supervisor DepartmentLimor Avivi-Arber PhD Barry Sessle DentistryThesis title: "Face Motor Cortex Neuroplasticity Associated with Alterations<strong>in</strong> the Oral Environment <strong>of</strong> the Adult Rat"Volume 25 <strong>Num</strong>ber 6 February 2009<strong>Program</strong> Committee MembersD.R. Hampson / PHARM. SCI. (Dir)J.O. Dostrovsky /PHYSIOLOGY (Advisor)W.M. Burnham / PHARMACOLOGYP. Carlen / INST. MED. SCIENCEL.F.De Nil / SPEECH LANG. PATHOL.Z. Jia / PHYSIOLOGYM. Lewis / HUMAN DEVELOPMENTAND APPLIED PSYCHOLOGYS. Nag / LAB. MED. PATHOBIOL.Kev<strong>in</strong> Da Silva PhD JoAnne McLaur<strong>in</strong> Lab. Med.Path.Thesis title: "Novel adjuvants for Alzheimer's Immunotherapy"Jean Hum MSc Pascal van Lieshout Sp-Lang PathThesis title: "The relationship between diet and the severity <strong>of</strong> stutter<strong>in</strong>g <strong>in</strong>people who stutter"Vladyslav Kushnir MSc Usoa Busto PharmacologyThesis title: "Investigat<strong>in</strong>g Smok<strong>in</strong>g Cue Salience <strong>in</strong> Individuals withComorbid Nicot<strong>in</strong>e Dependence and Major Depressive Disorder: An fMRIStudy"SPECIAL LECTUREJ. Peever / CELL AND SYSTEMSBIOLOGYJ. Roder / MOL. GENETICSB.J. Sessle / DENTISTRYM. Shoichet / INST. BIOMAT. &BIOMED. ENG.B. Stefanovic / MEDICAL BIOPHYSICSW. Trimble / BIOCHEMISTRYJ.W. Wells / PHARMACYJ.S. Yeomans / PSYCHOLOGYK. Zabjek / REHAB. SCI.UTNP/PIN Office: Room 102, Tanz <strong>Neuroscience</strong> Build<strong>in</strong>g,M5S 3H2.Telephone: 416-978-4894 Fax: 416-978-1878e-mail: p.neuroscience@utoronto.ca.http://www.utoronto.ca/neurosciSpecial lecture jo<strong>in</strong>tly hosted by UTNP and the Krembil<strong>Neuroscience</strong> Centre:Monday, March 2, 2009 5pmBRANKO KOPJAR, <strong>University</strong> <strong>of</strong> Wash<strong>in</strong>gton“Application <strong>of</strong> Adaptive Statistical Design <strong>in</strong> RandomizedControlled Trials <strong>of</strong> Sp<strong>in</strong>e Surgery: Theoretical Background andExample from Practice”<strong>Toronto</strong> Western Hospital, 399 Bathurst Street, Auditorium (WestW<strong>in</strong>g, 2nd Floor, Rm 2W-401)- 1 -


UPCOMING PIN DISTINGUISHED LECTURESPlease check http://www.utoronto.ca/neurosci for updates.RESCHEDULED - Wednesday, February 25, 2009 1pmMAIKEN NEDERGAARD, <strong>University</strong> <strong>of</strong> Rochester, Rochester, NY"Astrocytes Alive!"Medical Sciences Build<strong>in</strong>g, Rm 3153Wednesday, March 25, 2009 Time: TBAERIC NESTLER, Mt. S<strong>in</strong>ai School <strong>of</strong> Medic<strong>in</strong>e, New York, NYTitle: TBALocation: TBAThe Eighth Sackler Dist<strong>in</strong>guished Visit<strong>in</strong>g NeuroscientistThursday, April 2, 2009 Time: TBAERWIN NEHER, Max Planck Institute, Gött<strong>in</strong>gen Germany, 1991Nobel Prize W<strong>in</strong>ner In Physiology and Medic<strong>in</strong>eTitle: TBALocation: TBAThursday, April 16, 2009 Time: TBACHRIS McBAIN, National Institutes <strong>of</strong> Health, Bethesda, MDTitle: TBALocation: TBAThursday, May 7, 2009 Time: TBAMAY-BRITT MOSER, Norwegian <strong>University</strong> <strong>of</strong> Science andTechnology, Trondheim, NorwayTitle: TBALocation: TBAWednesday, June 24, 2009 Time: TBABITA MOGHADDAM, <strong>University</strong> <strong>of</strong> PittsburghTitle: TBALocation: TBANOTICE TO GRADUATING STUDENTSPlease notify the PIN <strong>of</strong>fice upon your graduation to ensure that youwill receive the notation "completed Collaborative <strong>Program</strong> <strong>in</strong><strong>Neuroscience</strong>" on your degree transcript as well as a separatecertificate suitable for fram<strong>in</strong>g from the PIN <strong>of</strong>fice to <strong>in</strong>dicate that youhave completed the program's requirements. Please let the <strong>of</strong>ficeknow the address you wish your certificate sent to and please also sendus your thesis title. If you have transferred from a Master’s degree toa Ph.D., please notify the PIN <strong>of</strong>fice.<strong>Neuroscience</strong>s & Mental Health (NMH) Research<strong>Program</strong> at The Hospital for Sick Children presents:Nurtur<strong>in</strong>g the Develop<strong>in</strong>g Bra<strong>in</strong>Friday, February 6th, 2009Hollywood Theatre (SickKids Auditorium)Rm 1246 – Elm W<strong>in</strong>g, 555 <strong>University</strong> Ave8:30 am – 8:55 amRegistration & C<strong>of</strong>fee <strong>in</strong> the Rotunda8:55 am – 9:00 amWelcome by Michael Salter, MD, PhD & Elizabeth Pang, PhD9:00 am – 9:50 am“Beyond early attachment: Issues <strong>in</strong> the design and dissem<strong>in</strong>ation <strong>of</strong>relationship build<strong>in</strong>g programs for parents <strong>of</strong> children andadolescents with mental health problems.”Charles E. Cunn<strong>in</strong>gham, PhD Psychologist, McMaster Children’sHospital, Offord Centre for Child Studies, Jack Laidlaw Chair &Pr<strong>of</strong>essor, Department <strong>of</strong> Psychiatry & Behavioural <strong>Neuroscience</strong>s,McMaster <strong>University</strong>, Hamilton9:50 am – 10:20 am“Maternal early adversity and the parent<strong>in</strong>g <strong>of</strong> sibl<strong>in</strong>gs: shared andnon-shared risks <strong>in</strong> development”Jennifer Jenk<strong>in</strong>s, PhD, CPsych Human Development & AppliedPsychology, OISE, <strong>University</strong> <strong>of</strong> <strong>Toronto</strong>10:20 am – 10:40 amC<strong>of</strong>fee Break <strong>in</strong> the Rotunda10:40 am – 11:10 am“Infant-caregiver attachment and later behaviour problems: Areview and meta-analysis.”Sheri Madigan, PhD <strong>Neuroscience</strong>s & Mental Health11:10 am – 11:40 am“Current parent<strong>in</strong>g stress moderates maternal maltreatment historyto <strong>in</strong>fluence cortisol reactivity <strong>in</strong> the <strong>in</strong>fant.”Leslie Atk<strong>in</strong>son, PhD Department <strong>of</strong> Psychology, Ryerson<strong>University</strong>, <strong>Toronto</strong>11:40 am – 12:30 pmOTHER NEUROSCIENCE NEWS“Maternal programm<strong>in</strong>g <strong>of</strong> neuroendocr<strong>in</strong>e systems throughepigenetic mechanisms.”Michael J. Meaney, PhD, CQ, FRSC Associate Director, DouglasInstitute Research Centre, James McGill Pr<strong>of</strong>essor, Depts <strong>of</strong>- 2 -


Psychiatry & Neurology/Neurosurgery, Director, <strong>Program</strong> for Study <strong>of</strong>Behaviour, Genes & Environment, McGill <strong>University</strong>, Montreal12:30 pm – 1:30 pmLunch <strong>in</strong> the Garden Terrace, Atrium, The Hospital for Sick ChildrenPlease contact Sharon Quilop to RSVP by February 3rd, 2009Phone: (416) 813-5756 Email: nmh.events@sickkids.caThe Ottawa Institute <strong>of</strong> Systems Biology, <strong>University</strong> <strong>of</strong>Ottawa And The National Research Council <strong>of</strong> CanadaPresent:Progress <strong>in</strong> Systems Biology Symposium“The Bra<strong>in</strong> and M<strong>in</strong>d”April 23-24, 2009Location: National Research Council <strong>of</strong> Canada, 100 Sussex Drive,Ottawa, CanadaKeynote Speakers:Dr. Seth GrantWellcome Trust Sanger Institute, Cambridge, EnglandDr. Hanfa ZouNational Chromatographic R&A Center, Dalian, Ch<strong>in</strong>aDr. Arturas Petronis<strong>University</strong> <strong>of</strong> <strong>Toronto</strong>, <strong>Toronto</strong>, CanadaDr. Alexandra GolbyHarvard Medical School, Boston, USADr. Frank Sharp<strong>University</strong> <strong>of</strong> California, Davis, USADr. Freda Miller<strong>University</strong> <strong>of</strong> <strong>Toronto</strong>, <strong>Toronto</strong>, CanadaEarly Bird Registration Deadl<strong>in</strong>e and Poster Submission: March 1,2009For more <strong>in</strong>formation and to register, please visit: www.oisb.caContact <strong>in</strong>formation: sysbio@uottawa.ca or phone (613) 562-5800 ext.8073Announc<strong>in</strong>g the 2009 Wiscons<strong>in</strong> Symposium on Emotion"Adolescence, Bra<strong>in</strong> Plasticity and Psychopathology"April 23-24, 2009Monona Terrace, Madison WIPlease see www.healthemotions.org/symposium for more <strong>in</strong>formationand to register.XXXIst International Symposium <strong>of</strong> the GRSNC"Breathe, Walk and Chew – The neural challenge"May 4-5, 2009Université de MontréalWe are pleased to announce that the XXXIst InternationalSymposium <strong>of</strong> the Groupe de recherche sur le système nerveuxcentral, entitled "Breathe, Walk and Chew – The neural challenge"will be held on May 4-5, 2009 at Pavillon 3200 Jean-Brillant, RoomB-2245 at the Université de Montréal.The symposium is organized by Dr Arlette Kolta, Dr Réjean Dubucand Dr Jean-Pierre Gossard. This will be a symposium on theneuronal mechanisms, circuits and networks underly<strong>in</strong>g genesis <strong>of</strong>three rhythmic movements <strong>in</strong> vertebrates: mastication, respirationand locomotion. The symposium will focus on recent developmentsmade at three levels <strong>of</strong> <strong>in</strong>vestigation:1) The molecular and genetic factors determ<strong>in</strong><strong>in</strong>g the functionalorganization <strong>of</strong> the circuits controll<strong>in</strong>g these three movements;2) The ionic and neuronal mechanisms responsible forrhythmogenesis <strong>in</strong> these circuits;3) The control and modulation <strong>of</strong> the circuits by descend<strong>in</strong>g <strong>in</strong>putsand sensory <strong>in</strong>formation.The last session will present retrospective and future perspectives <strong>of</strong>the work <strong>of</strong> Serge Rossignol, James P. Lund, and Jack Feldman allthree pioneers <strong>in</strong> their own field, locomotion, mastication andrespiration respectively.Registration is now open. Please visithttp://www.grsnc.umontreal.ca/31s/ for <strong>in</strong>formation.The poster is available athttp://www.grsnc.umontreal.ca/31s/31s_poster.pdfSubmissions are <strong>in</strong>vited for a limited number <strong>of</strong> poster presentations.A selection will be made from the submitted abstracts.Deadl<strong>in</strong>e for poster submissions: Tuesday, March 31, 2009.POSITIONS AVAILABLEUNIVERSITY OF TORONTO ANDAFFILIATED INSTITUTIONSRESEARCH TECHNICIAN ORRESEARCH ASSOCIATE POSITIONPosition open - February 2009<strong>University</strong> <strong>of</strong> <strong>Toronto</strong>Molecular biologist or biochemist research technician (M.Sc.degree), or Research Associate (Ph.D. degree) wanted for a position<strong>in</strong> a neurobiology/molecular pharmacology research laboratory at- 3 -


the <strong>University</strong> <strong>of</strong> <strong>Toronto</strong>. This position requires someone withexpertise <strong>in</strong> molecular biology and biochemical (prote<strong>in</strong>) techniqueswith at least 1 year experience (post degree). Expertise <strong>in</strong> DNAclon<strong>in</strong>g and manipulation <strong>in</strong>clud<strong>in</strong>g PCR is required. Experience withcell culture, prote<strong>in</strong> purification, radioligand b<strong>in</strong>d<strong>in</strong>g techniques,and/or work<strong>in</strong>g with mutant mice is also desirable. Previousexperience <strong>in</strong> organiz<strong>in</strong>g and runn<strong>in</strong>g a research laboratory is a plus.Salary range = $45-60K depend<strong>in</strong>g on qualifications. Please refer toJOB #9 and send CV to: sam.dalfonso@utoronto.ca.POSTDOCTORAL POSITIONPostdoctoral Fellow Sp<strong>in</strong>al Cord Injury Rehabilitation(Canada)Rehabilitation Eng<strong>in</strong>eer<strong>in</strong>g Laboratory, <strong>Toronto</strong>Rehabilitation Institute and Restorative Motor ControlLaboratory, Department <strong>of</strong> Physical Therapy, <strong>University</strong> <strong>of</strong><strong>Toronto</strong>, <strong>Toronto</strong> CanadaPr<strong>of</strong>. Molly Verrier is an Associate Pr<strong>of</strong>essor <strong>in</strong> the Department <strong>of</strong>Physical Therapy and Rehabilitation Science at the <strong>University</strong> <strong>of</strong><strong>Toronto</strong> www.physicaltherapy.utoronto.ca and Senior Scientist at theSp<strong>in</strong>al Cord Injury Lyndhurst Centre <strong>of</strong> the <strong>Toronto</strong> RehabilitationInstitute (<strong>Toronto</strong> Rehab) www.torontorehab.on.ca. Dr Milos Popovicis a Pr<strong>of</strong>essor <strong>in</strong> the Institute <strong>of</strong> Biomaterials and BiomedicalEng<strong>in</strong>eer<strong>in</strong>g at the <strong>University</strong> <strong>of</strong> <strong>Toronto</strong> and the <strong>Toronto</strong> Rehab Chair<strong>in</strong> Sp<strong>in</strong>al Cord Injury Research www.toronto-fes.ca.Description: One postdoctoral position for two to three years isavailable <strong>in</strong> the Rehabilitation Eng<strong>in</strong>eer<strong>in</strong>g Laboratory, LyndhurstCentre and the Restorative Motor Control Laboratory, RehabilitativeSciences, <strong>University</strong> <strong>of</strong> <strong>Toronto</strong>. The position will <strong>in</strong>volve exam<strong>in</strong><strong>in</strong>gcomponents <strong>of</strong> restorative motor control <strong>in</strong>clud<strong>in</strong>g recovery andresponse to new <strong>in</strong>terventions <strong>in</strong> sp<strong>in</strong>al cord <strong>in</strong>jury (SCI), <strong>in</strong> cl<strong>in</strong>icalstudies. The applicant will be required to have a PhD as well asexperience <strong>in</strong> Neurorehabilitation and/or Rehabilitation Eng<strong>in</strong>eer<strong>in</strong>g.Requirements: A PhD is required along with excellent researchtra<strong>in</strong><strong>in</strong>g. An understand<strong>in</strong>g <strong>of</strong> rehabilitation and SCI will beconsidered a def<strong>in</strong>ite advantage. The candidate must also becommitted to develop<strong>in</strong>g funded research projects that <strong>in</strong>volvegraduate students and apply for post doctoral fund<strong>in</strong>g dur<strong>in</strong>g thecourse <strong>of</strong> the award. As well candidates should consider currentfund<strong>in</strong>g opportunities available from the Ontario NeurotraumaFoundation SCI - 2009 Graduate and Post-doctoral FellowshipAwards www.onf.org .Environment: Important cl<strong>in</strong>ical resources <strong>in</strong>clude; <strong>in</strong>patient andoutpatient SCI population, a specialized SCI neurorehabilitationprogram, a cl<strong>in</strong>ical SCI data base as well as neurophysiologylaboratories for electrophysiological, k<strong>in</strong>ematic, k<strong>in</strong>etic, upper limb,locomotion and postural control test<strong>in</strong>g. Physical therapy, physiatry,rehabilitation eng<strong>in</strong>eer<strong>in</strong>g and occupational therapy are all strongservices, each l<strong>in</strong>ked to the <strong>University</strong> <strong>of</strong> <strong>Toronto</strong> an exemplarydesignated teach<strong>in</strong>g-tra<strong>in</strong><strong>in</strong>g location. The sp<strong>in</strong>al cord rehabilitationresearch program has a group <strong>of</strong> dist<strong>in</strong>guished SCI scientists fundedfrom Canadian Institute <strong>of</strong> Health Research, Natural Sciences andEng<strong>in</strong>eer<strong>in</strong>g Research Council <strong>of</strong> Canada, the Ontario NeurotraumaFoundation, Heart and Stroke Foundation, Christopher and DanaReeve Foundation, The Physicians' Services IncorporatedFoundation and the SCI-Solutions Network. The environment is one<strong>of</strong> enquiry <strong>in</strong> association with other <strong>in</strong>vestigators, Cl<strong>in</strong>ical Fellows,postdoctoral fellows, Master’s and PhD students from Canada andabroad. Presently the team has 14 pr<strong>in</strong>cipal <strong>in</strong>vestigators and morethan 70 team members. More <strong>in</strong>formation about the presentactivities <strong>of</strong> the group can be found at www.toronto-fes.ca andwww.torontorehab.on.ca/research/<strong>in</strong>dex.htmApplication: Send (email preferred) CV and brief statements aboutyour research <strong>in</strong>terests to:Molly Verrier, Associate Pr<strong>of</strong>essor, Department <strong>of</strong> Physical Therapy160-500 <strong>University</strong> Avenue <strong>Toronto</strong>, Ontario M5G 1V7 Tel: (416)978-5935 Fax (416)946-8643 m.verrier@utoronto.caOVERSEASPOSTDOCTORAL POSITIONSSydney, Australia3 Post doctoral Positions Available- Mathematical Model<strong>in</strong>g- Cell Biology- Cellular ElectrophysiologyApplications are <strong>in</strong>vited for three Post-doctoral Research Scientiststo jo<strong>in</strong> the Mark Cowley Lidwill Research <strong>Program</strong> <strong>in</strong> CardiacElectrophysiology at the VCCRI and to work on the biology <strong>of</strong>hERG K+ channels and genotype-phenotype relationships <strong>in</strong> LongQT syndrome type 2.Please refer to our website www.victorchang.edu.au for furtherdetails on the <strong>in</strong>stitute and the positions available.Applicants should send a curriculum vitae and the names <strong>of</strong> threereferees to:Ms Carla Northam, HR Manager,Victor Chang Cardiac Research Institute,405 Liverpool Street, Darl<strong>in</strong>ghurst, Sydney, NSW 2010, Australia.Or Email: c.northam@victorchang.edu.auSUMM ER POSI TI ON WANTEDMy name is Graham Mazereeuw and I am a 3 rd year IntegratedScience student at Carleton <strong>University</strong>. I am really keen to cont<strong>in</strong>uewith research over the summer and, more specifically, I would liketo cont<strong>in</strong>ue my research <strong>in</strong> neuroscience. Currently, I am work<strong>in</strong>g onmy Honours Thesis at the Department <strong>of</strong> <strong>Neuroscience</strong> with Dr.Holahan where I study levels <strong>of</strong> hippocampal BDNF geneexpression <strong>in</strong> rats after acute noise stress. I hope to further myresearch experience with a volunteer position at the Institute <strong>of</strong>Mental Health Research at the Royal Ottawa Hospital <strong>in</strong> the com<strong>in</strong>g- 4 -


weeks, and eventually apply to medical school. I am open to any type<strong>of</strong> research position and I am certa<strong>in</strong>ly will<strong>in</strong>g to experience any newarea <strong>of</strong> study. If I seem like a good fit for your lab, please contactme anytime at: gmazeree@connect.carleton.ca or 613-697-8036.- 5 -

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