Annual Report of Activities CNC 2011 - Center for Neuroscience and ...

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“O papel da adenosina e do receptor A2A na resposta imunitária a Candida albicans.” FCT Refª: 01/06/2011 To 49.832,00 19.943,81 Coordinator: Teresa Maria Gonçalves PTDC/SAU-‐MIC/115598/2009 31/05/2013 "Nanoquimica de compósitos magnéticos/luminescentes para aplicações de diagnóstico médico in vitro" Coordinator: António Guiomar FCT Refª: PTDC/QUI/67712/2006 01/01/2008 to 31/03/2011 15.300,00 2558,03 Participants: Universidade de Aveiro "Reconstrução e análise sistémica da rede reaccional de espécies reactivas de oxigénio, azoto e enxofre em sistemas fisiológicos representativos." FCT Refª: PTDC/QUI/70523/2006 01/01/2008 to 31/12/2010 162.752,00 17.954,88 Coordinator: Armindo Salvador Participants: Fundação da Faculdade de Ciências, Universitat de Lleida. "BIOINK -‐ Aprendizagem incremental de Kernel Machines para análise de dados em bioinformática" Coordinator: Paula Verissimo FCT Refª: PTDC/EIA/71770/2006 01/01/2008 to 31/12/2011 4.200,00 838,85 Participants: Faculdade de Ciências e Tecnologia da Universidade de Coimbra, Instituto Superior de Engenharia de Coimbra. "Proteases de Polens, relevância nas doenças alérgicas." Coordinator: Paula Verissimo FCT Refª: PTDC/SAU-‐ESA/72571/2006 01/05/2008 to 22/05/2012 199.850,00 68.656,83 164“Papel do ATP e dos seus receptores P2Y1 na neuroprotecção” Coordinator: Rodrigo Cunha FCT Refª: PTDC/SAU-‐FCF/100423/2008 18/03/2010 to 17/09/2012 189.697,00 66.660,79 “Acoplamento neurovascular entre a actividade neuronal e o fluxo sanguineo no encéfalo mediado pelo óxido nítrico” Coordinator: João Laranjinha FCT Refª: PTDC/SAU-‐NEU/108992/2008 01/05/2010 to 30/04/2013 100.000,00 42.435,51
“Perfis dinâmicos do óxido nítrico no cérebro: regulação da respiração celular com implicações para a doença de Alzeheimer e para o envelhecimento” Coordinator: João Laranjinha FCT Refª: PTDC/SAU-‐NEU/103538/2008 01/06/2010 to 31/05/2013 100.000,00 51.676,66 “HotMetal-‐Estratégias de resistência a metais pesados e disseminação de resistências a antibióticos nas fontes marinhas hidrotermais” Coordinator: Milton Costa FCT Refª: PTDC/MAR/109057/2008 01/06/2010 to 31/05/2013 9.000,00 1.200,44 Participants: IMAR “Análise das alterações da transcrição em modelos cerebrais e periféricos da doença de Huntington -‐ influência da modulação das desacetilases das histonas” FCT Refª: PTDC/SAU-‐FCF/108056/2008 05/02/2010 to 04/02/2013 199.999,00 74.350,77 Coordinator: Ana Cristina Rego “Papel da proteólise da ataxina-‐3 mediada por calpaínas na doença de Machado-‐Joseph: terapia molecular com vectores virais” Coordinator: Luis de Almeida FCT Refª: PTDC/SAU-‐NEU/099307/2008 05/02/2010 to 04/02/2013 107.000,00 38.660,68 “Genes FKS, CHS e de sintese de melanina em Alternaria infectoria: a combinação para o oportunismo” FCT Refª: 01/03/2010 to 100.000,00 39.051,96 Coordinator: Teresa Gonçalves PTDC/SAU-‐ESA/108636/2008 28/02/2012 Papel da Fisiologia Mitocondrial na Resistência das Células Estaminais Tumorais à Quimioterapia FCT Refª: 01/04/2010 to 143.016,00 33.473,16 Coordinator: Paulo Oliveira PTDC/QUI-‐BIQ/101052/2008 31/03/2013 165“Biorstimul -‐ Desenvolvimento e construção de um novo conceito de bioreactor para a caracterização biomecânica e bioquíma de tecidos de cartilagem desenvolvidos in-vitro”FCT Refª: PTDC/EME-‐PME/103578/2008 16/03/2010 to 15/03/2013 41.600,00 7.324,54 Coordinator: Celeste Lopes Participants: Universidade Aveiro
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Center for Neuroscience and Cell Bi
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Introduction |General Objectives5CN
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OrganizationThe Center for Neurosci
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Neuroscience and Disease AreaCoordi
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Mitochondrial Dysfunction and Si
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Glutamatergic Synapses GroupHead: A
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Neuroprotection and Neurogenesis in
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Neuronal Cell Death and Neuroprotec
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Mitochondrial Dysfunction and Signa
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Molecular Mechanisms of Disease Gro
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26fluoxetine promotes the prolif
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28Project 3: B cells against C
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Finley, L.W., Carracedo, A., Le
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Santos, S.D., Iuliano, O., Ribe
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Molecular Biotechnology Group Vec
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Molecular Biotechnology GroupHead:
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Molecular Systems Biology GroupHead
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Structural and Computational Biolog
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Vectors and Gene Therapy GroupHead:
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Biomaterials and Stem Cell-Based Th
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Pharmacometrics GroupHead: Amílcar
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4919 (from retinal pigment epit
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Khadem, M., Camacho, R., Nóbre
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IN PRESS Correia, S., Vinhas, R
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Mitochondrial Toxicology and Dis
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Redox Biology in Health and Disease
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(2011) Changes in glucose uptak
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6223. Duarte, F.V., Teodoro, J.S
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Microbiology of Extreme Environm
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Medical Mycology - Yeast Research G
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IN PRESS Anjos, J., Fernandes,
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Inorganic Biochemistry and Molec
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72Main Achievements A) New Gd(II
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appearance. Insulin and c-‐p
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IN PRESS Barosa, C., Silva, C.,
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78Cellular Immunology and Oncobi
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inhibiting TNF-‐α and CCL5
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Infection, Phagocytosis and Pathoge
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84metabolism as well as on gen
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Ramalho-‐Santos, J. (2011) H
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1. Psychiatry Research Carlos Pa
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Fanous, A.H., Middleton, F., Ge
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PUBLICATIONS Santos, M.J., Marque
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Andrade, P., Gonçalo, M. (2011
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PUBLICATIONS Costa, A.L., Silva,
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InternationalizationInternationaliz
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Role of difusible and contact
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Retroviral-‐like membrane-
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Harvard Medical School), Mª Ot
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5 th Annual Meeting on Cell Sig
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Graduate Studies ProgrammeThe Cent
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Excitotoxic Signaling October 19
Page 113 and 114: FEBRUARY 3.2.2011 Peripheral nervo
Page 115 and 116: 11.11.2011 Keeping mitochondria i
Page 117 and 118: Ana Raquel Santos Calhôa Mano
Page 119 and 120: Paula Cristina Cardoso Ramos Mo
Page 121 and 122: Master thesis Ana Isabel Reis S
Page 123 and 124: Marta Maria Vieira Matutino Fal
Page 125 and 126: Outreach ProgrammeThe Outreach Pr
Page 127 and 128: Technology TransferTranslational r
Page 129 and 130: Core FacilitiesCNC research Core
Page 131 and 132: FLOW CYTOMETRY UNITHead of Unit: Is
Page 133 and 134: MASS SPECTROSCOPY UNITHead of Unit:
Page 135 and 136: ServicesCNC Laboratório Associad
Page 137 and 138: 137Mitochondrial DNA (mtDNA) and
Page 139 and 140: Neuro-Ophthalmology Genetics Labora
Page 141 and 142: AIBILI Report of Activities2011141
Page 143 and 144: 1433 genes will be analysed by
Page 145 and 146: 8. A multicenter, masked, random
Page 147 and 148: 147decarboxylase inhibitor (DDCI)
Page 149 and 150: 4. Publications (2011) 1. Alves
Page 151 and 152: 46. Ribeiro ML, Figueira J, Cun
Page 153 and 154: 153Funding
Page 155 and 156: Introduction In 2011 funding of
Page 157 and 158: ONGOING PROJECTSTitle Financing A
Page 159 and 160: “A restrição calórica aumen
Page 161 and 162: "Planctomyces -‐ uma linhage
Page 163: “A enigmática maltocinase de
Page 167 and 168: “Mecanismos Moleculares do Trá
Page 169 and 170: QREN-‐Amilotera: 021622 Agênc
Page 171 and 172: 171List of Staff and Research Stude
Page 173 and 174: List of Staff and Research Students
Page 175 and 176: Mª Carmen Alpoim (Associate Prof.,
Page 177 and 178: Manuella Kaster 30Marco André Coel
Page 179 and 180: Diana Dinis Azenha 100Diana Jurado
Page 181 and 182: Miranda Melle 100Nélio Gonçalves
Page 183 and 184: Diana Matias 100Dina Farinha 100Dio
Page 185 and 186: MDAntónio MacedoCollaboratorCristi
Page 187 and 188: Research Staff and Students | Resea
Page 189 and 190: Carla Maria Nunes Lopes 100Carlos A
Page 191 and 192: Grant TechnicianBruno Carreira 100C
Page 193 and 194: Post-Doc MembersAkhilesh Rai 10Ana
Page 195 and 196: MSc StudentsAlbert Rafels Ybern 30A
Page 197 and 198: Diana Jurado S. Serra 100Filipa Lib
Page 199 and 200: Grant TechnicianAlexandra M. Abrunh
Page 201 and 202: MSc StudentsAdriana Branco 100Andre
Page 203 and 204: Paula Mota 100Sandra Catarina G. Am
Page 205 and 206: 205
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