Plenary Oral Presentations - Macquarie University Hospital

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16 th International Meeting of the Leksell Gamma Knife ® SocietyMarch 2012, Sydney, AustraliaMA-68A retrospective study of GKRS-treated MET patients:Tumor numbers of two-four versus five or moreMasaaki Tamamoto, Takuya Kawabe, Bierta E. Barfod, Yoichi UrakawaKatsuta Hospital Mito GammaHouseObjective: The role of stereotactic radiosurgery for brain MET patients with tumor numbers (TNs) offive or more is not fully understood.Methods: Among our consecutive series of 2502 patients with brain METs, who underwent GKRSduring the 1998-2011 period, 1775 (740 females, 1035 males, mean age; 65 [range; 19-92] years)with TNs of two or more (median; 5, maximum; 89) were chosen for this retrospective study. Originaltumor most-commonly stemmed from the lung (1183 patients, 66.6%), followed by breast (214,12.1%), lower alimentary tract (109, 6.1%), upper alimentary tract (67, 3.6%), kidney (60, 3.9%),other organs (110, 6.2%) and unknown (34, 2.0%). Among the 1775 patients, 796 had TNs of twofour(group-A) and the other 975 of five or more (group-B).Results: Median survival time (MST) after GKRS was significantly longer in group-A (7.4 months)than in group-B (5.9, p
16 th International Meeting of the Leksell Gamma Knife ® SocietyMarch 2012, Sydney, AustraliaMA-73What is the best grading system in stereotactic radiosurgeryfor brain metastases, RTOG-RPA, SIR, BSBM, GPA or a modified RPA?1Toru Serizawa, 2 Osamu Nagano, 3 Yoshinori Higuchi, 2 Shinji Mastuda, 2 Junichi Ono,3Naokatsu Saeki, 1 Tatsuo Hirai, 4 Msaaki Yamamoto1Tokyo Gamma Unit Center, Tsukiji Neurological Clinic, Tokyo, Japan2Gamma Knife House, Chiba Cardiovascular Center, Ichihara, Japan3Department of Neurological Surgery, Chiba University, Chiba, Japan4Katsuta Hospital Mito GammaHouse, Hitachinaka, JapanObjective: A new index for Recursive Partitioning Analysis (RPA) classification of patients with brainmetastases proposed by Masaaki Yamamoto was applied to our patient series for comparison withpreviously established systems including the original RPA, score index for SRS (SIR), basic scorefor brain metastases (BSBM) and graded prognostic assessment (GPA), in order to ascertain whichgrading system is the best for gamma knife surgery (GKS).Methods: Twenty-two hundred and forty-six patients with brain metastases, treated by the first authorwith GKS during the 1998-2010 period at Chiba Cardiovascular Center and Tsukiji NeurologicalClinic, were analyzed.Results: There were 1341 men and 895 women. Median age was 65, range 7-94. Extracranial diseasestatus was judged to be “controlled” in 281. Median tumor numbers were 3, range 1-100. The mostcommon primary site was the lung (1490 cases), followed by gastro-intestine (277), breast (230),uro-genital (136) and others (113). There were 133 (MST 24.8Mo) RPA class I, 1812 (7.8) II and301 (3.6) III cases, with statistically significant differences (p
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RRadatz Matthias 12, 16Radatz Matth
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Plenary Oral Presentations - Macquarie University Hospital

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