Kamini Nagandran Nagandran1, Chua Kien Hui3, Nor Hamdan Md ...

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Induction with HMG and EHMGextracts compared to control0.5%HMG 1.62-folds1%HMG 2.13-folds0.5%EHMG 05%EHMG3.67-folds367 1%EHMG 2.84-foldsSOX-9 is a domain transcription factor,been identified as a key molecule inchondrocytes differentiation duringchondrogenesis.The expression of SOX-9 increased in the EBN extract treatedchondrocytes (significant in EHMG induction) that the phenotype ofchondroyctes were maintained better by EBN extract.
Induction with HMG and EHMGextracts compared to control0.5%HMG 1.22-folds1%HMG 1.49-folds0.5%EHMG 1.27-folds1%EHMG 1.08-foldsProteoglycan a major component ofextracellular matrix, essential forcartilage rigidity and mechanical loadfunction (IozzoIozzo, 1998).HMG showed better enhancement of major proteoglycan encoding geneexpression (ACP) compared to the control and EHMG as well.
Page 1: Kamini Nagandran 1 , Chua Kien Hui
Page 5 and 6: Type II collagen is a cartilage spe
Page 9 and 10: EBN known as Yan Wo by the Chinese
Page 11: Traditional Chinese Medicine believ
Page 17 and 18: Fig 2(a): The cells are polygonal i
Page 19 and 20: Induction with HMG and EHMG extract
Page 21: CONTROL 0.5% HMG 1% HMG 0.5% EHMG 1
Page 25: In this study the changes on chondr
Page 30 and 31: (Odaet al., 1998; Goh et al., 2000)
Page 32 and 33: (Boileauet al.,2007; Chua et al., 2
Page 34: Preparation of master mix:•2X RT

Kamini Nagandran Nagandran1, Chua Kien Hui3, Nor Hamdan Md ...

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