Breast Cancer - Department of Surgery at SUNY Downstate Medical ...
Breast Cancer - Department of Surgery at SUNY Downstate Medical ...
Breast Cancer - Department of Surgery at SUNY Downstate Medical ...
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Stage 0 – TisDuctal lC Carcinoma In Situ (DCIS)• Excision and Radi<strong>at</strong>ion Therapy (RT) vsExcision alone• Prospective randomized trials• N<strong>at</strong>ional Surgical Adjuvant <strong>Breast</strong> Project (NSABP) B17• European Organiz<strong>at</strong>ion for Research and Tre<strong>at</strong>ment <strong>of</strong> <strong>Cancer</strong> (EORTC)• United Kingdom Trial• RT reduced ipsil<strong>at</strong>eral breast tumor recurrence by 50-60%.• Recurrence with excision 32% vs 16% in excision and RT <strong>at</strong> 10yrs• 50% <strong>of</strong> recurrences were invasive ca in both groups.• No survival lb benefit from RT.
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